Amol Sahebrao Suryawanshi

Corneal Immunology, Immunopathology, Keratitis, Th17, IL-17A, Treg, Immunoregulation

Works (52)

Updated: February 19th, 2026 16:49

2025 article

Injectable PLGA-based In Situ Forming Subconjunctival Implant for Sustained Ocular Delivery of Ketotifen Fumarate: Formulation, Drug Release, and Biocompatibility Studies

Mita, N., Kang, X., Chen, P., Fasina, O., Howard, S., Bowden, A.-C., … Babu, R. J. (2025, June 2). AAPS PharmSciTech, Vol. 26.

By: N. Mita*, X. Kang*, P. Chen*, O. Fasina*, S. Howard*, A. Bowden*, R. McMullen*, A. Suryawanshi n, R. Babu

author keywords: in situ forming subconjunctival implant; ketotifen fumarate; PLGA
MeSH headings : Ketotifen / administration & dosage; Ketotifen / chemistry; Polylactic Acid-Polyglycolic Acid Copolymer / chemistry; Humans; Drug Liberation; Animals; Delayed-Action Preparations / chemistry; Delayed-Action Preparations / administration & dosage; Cell Line; Viscosity; Biocompatible Materials / chemistry; Biocompatible Materials / administration & dosage; Lactic Acid / chemistry; Polyglycolic Acid / chemistry; Chemistry, Pharmaceutical / methods; Drug Implants / administration & dosage; Drug Implants / chemistry; Administration, Ophthalmic; Drug Delivery Systems / methods; Conjunctiva / drug effects; Conjunctiva / metabolism
topics (OpenAlex): Ocular Surface and Contact Lens; Advanced Drug Delivery Systems; Advancements in Transdermal Drug Delivery
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 9, 2025

2024 article

Airspaces-derived exosomes contain disease-relevant protein signatures in a mouse model of cystic fibrosis (CF)-like mucoinflammatory lung disease

Mao, Y., Suryawanshi, A., Patial, S., & Saini, Y. (2024, September 25). Frontiers in Pharmacology, Vol. 15.

By: Y. Mao n, A. Suryawanshi n, S. Patial* & Y. Saini n

author keywords: exosome; proteomics; airspace; Scnn1b-Tg+; lung; mucoinflammation
topics (OpenAlex): Extracellular vesicles in disease; Inhalation and Respiratory Drug Delivery; Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 1, 2024

2024 journal article

Cellular interactions in tumor microenvironment during breast cancer progression: new frontiers and implications for novel therapeutics

Frontiers in Immunology, 15.

By: T. Akinsipe*, R. Mohamedelhassan*, A. Akinpelu*, S. Pondugula*, P. Mistriotis*, L. Avila*, A. Suryawanshi*

MeSH headings : Humans; Tumor Microenvironment; Neoplasms; Cell Communication; Immune Evasion; Stromal Cells
topics (OpenAlex): Immune cells in cancer; Cancer Immunotherapy and Biomarkers; Immunotherapy and Immune Responses
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2024 article

Protocol for X-ray irradiation of C57BL/6J recipient mice followed by the transplantation of mTomato-expressing bone marrow cells

Vo, T., Kumar, R., Lamichhane, R., Choudhary, I., Rekha, K. C., Mao, Y., … Saini, Y. (2024, December 18). STAR Protocols, Vol. 6.

By: T. Vo n, R. Kumar n, R. Lamichhane n, I. Choudhary n, K. Rekha n, Y. Mao n, K. Paudel n, A. Suryawanshi n ...

MeSH headings : Animals; Mice, Inbred C57BL; Mice; Bone Marrow Transplantation / methods; X-Rays; Bone Marrow Cells / cytology; Transplantation Chimera
topics (OpenAlex): Cancer Cells and Metastasis; Hematopoietic Stem Cell Transplantation; Immunotherapy and Immune Responses
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 19, 2024

2024 journal article

Rapidly Dissolving Trans-scleral Microneedles for Intraocular Delivery of Cyclosporine A

AAPS PharmSciTech, 25(2).

MeSH headings : Animals; Swine; Cyclosporine; Emulsions; Eye; Immunosuppressive Agents; Drug Delivery Systems
topics (OpenAlex): Advancements in Transdermal Drug Delivery; Ocular Surface and Contact Lens; Advanced Drug Delivery Systems
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2024 journal article

The immunobiology of corneal HSV-1 infection and herpetic stromal keratitis

Clinical Microbiology Reviews.

By: F. Antony*, D. Kinha n, A. Nowinska*, B. Rouse* & A. Suryawanshi n

Ed(s): G. Forrest

MeSH headings : Humans; Keratitis, Herpetic / immunology; Keratitis, Herpetic / virology; Herpesvirus 1, Human / immunology; Herpesvirus 1, Human / physiology; Antiviral Agents / therapeutic use; Animals
topics (OpenAlex): Herpesvirus Infections and Treatments; Ocular Surface and Contact Lens
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 22, 2024

2023 journal article

Role of IL-27 in HSV-1–Induced Herpetic Stromal Keratitis

The Journal of Immunology, 211(3), 474–485.

By: F. Antony*, C. Pundkar*, M. Sandey*, A. Mishra* & A. Suryawanshi*

MeSH headings : Animals; Female; Male; Mice; Cornea / immunology; Cornea / virology; Herpesvirus 1, Human; Interferon-beta / immunology; Interleukins / immunology; Keratitis, Herpetic / immunology; Macrophages / immunology; Mice, Knockout; Virus Shedding; Th1 Cells / immunology; Immunity, Innate
topics (OpenAlex): Herpesvirus Infections and Treatments; Immunotherapy and Immune Responses; Immune Response and Inflammation
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2023 journal article

Role of Innate Interferon Responses at the Ocular Surface in Herpes Simplex Virus-1-Induced Herpetic Stromal Keratitis

Pathogens, 12(3), 437.

By: J. Ren*, F. Antony*, B. Rouse* & A. Suryawanshi*

topics (OpenAlex): Herpesvirus Infections and Treatments; interferon and immune responses
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2023 journal article

Targeting β-catenin signaling using XAV939 nanoparticles in tumor microenvironment-conditioned macrophages promote immunogenicity

Heliyon, 9(6), e16688.

By: C. Pundkar*, F. Antony*, X. Kang*, A. Mishra*, R. Babu*, P. Chen*, F. Li*, A. Suryawanshi*

topics (OpenAlex): Immunotherapy and Immune Responses; Phagocytosis and Immune Regulation; Cancer Immunotherapy and Biomarkers
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2023 journal article

Targeting β-catenin using XAV939 nanoparticle promotes immunogenic cell death and suppresses conjunctival melanoma progression

International Journal of Pharmaceutics, 640, 123043.

By: F. Antony*, X. Kang*, C. Pundkar*, C. Wang*, A. Mishra*, P. Chen*, R. Babu*, A. Suryawanshi*

MeSH headings : Animals; beta Catenin / genetics; beta Catenin / metabolism; beta Catenin / pharmacology; Immunogenic Cell Death; Wnt Signaling Pathway; Melanoma / drug therapy; Cell Line, Tumor
topics (OpenAlex): Cancer Mechanisms and Therapy; Prostate Cancer Treatment and Research
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2022 journal article

Development of OX40 agonists for canine cancer immunotherapy

IScience, 25(10), 105158.

By: D. Ruiz*, C. Haynes*, J. Marable*, C. Pundkar*, R. Nance*, D. Bedi*, P. Agarwal*, A. Suryawanshi* ...

topics (OpenAlex): Immunotherapy and Immune Responses; Veterinary Oncology Research; T-cell and B-cell Immunology
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2022 journal article

Innate immunity dysregulation in aging eye and therapeutic interventions

Ageing Research Reviews, 82, 101768.

By: S. Das*, Z. Ahmad*, A. Suryawanshi* & A. Kumar*

MeSH headings : Humans; Aging / physiology; Immunity, Innate; Immune System; Cellular Senescence; Eye Diseases / therapy
topics (OpenAlex): Neutrophil, Myeloperoxidase and Oxidative Mechanisms; Corneal Surgery and Treatments; Ocular Surface and Contact Lens
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2021 journal article

IFN-λ Regulates Neutrophil Biology to Suppress Inflammation in Herpes Simplex Virus-1–Induced Corneal Immunopathology

The Journal of Immunology, 206(8), 1866–1877.

MeSH headings : Animals; Antiviral Agents / therapeutic use; Cornea / pathology; Cytokines / metabolism; Cytokines / therapeutic use; Cytotoxicity, Immunologic; Disease Models, Animal; Herpesvirus 1, Human / physiology; Humans; Immune Tolerance; Immunity, Innate; Inflammation / immunology; Keratitis, Herpetic / immunology; Keratitis, Herpetic / therapy; Macrophages / immunology; Mice; Mice, Inbred C57BL; Mucous Membrane / immunology; Mucous Membrane / pathology; Neutrophils / immunology; Reactive Oxygen Species / metabolism
topics (OpenAlex): Herpesvirus Infections and Treatments; Immune Response and Inflammation; interferon and immune responses
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2021 journal article

Irg1/itaconate metabolic pathway is a crucial determinant of dendritic cells immune-priming function and contributes to resolute allergen-induced airway inflammation

Mucosal Immunology, 15(2), 301–313.

By: A. Jaiswal*, J. Yadav*, S. Makhija*, S. Mazumder*, A. Mitra*, A. Suryawanshi*, M. Sandey*, A. Mishra*

MeSH headings : Allergens; Animals; Dendritic Cells / immunology; Dendritic Cells / metabolism; Dendritic Cells / pathology; Hydro-Lyases / metabolism; Inflammation / immunology; Inflammation / metabolism; Inflammation / pathology; Metabolic Networks and Pathways; Mice; Pyroglyphidae / immunology; Succinates / immunology; Succinates / metabolism; Th2 Cells
topics (OpenAlex): Immune cells in cancer; Immune Response and Inflammation; Immune Cell Function and Interaction
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 21, 2024

2021 journal article

Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients

Scientific Reports, 11(1).

By: J. Marable*, D. Ruiz*, A. Jaiswal*, R. Bhattacharya*, R. Pantazes*, P. Agarwal*, A. Suryawanshi*, D. Bedi* ...

MeSH headings : Animals; CTLA-4 Antigen / antagonists & inhibitors; Dog Diseases / drug therapy; Dogs; Immune Checkpoint Inhibitors / therapeutic use; Neoplasms / drug therapy; Neoplasms / veterinary; Single-Domain Antibodies / therapeutic use
topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; T-cell and B-cell Immunology; Immunotherapy and Immune Responses
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2021 journal article

Near-infrared light triggered activation of pro-drug combination cancer therapy and induction of immunogenic cell death

International Journal of Pharmaceutics, 607, 120972.

By: X. Kang*, Y. Cai*, Q. Wang*, C. Wang*, W. Chen*, W. Yang*, A. Suryawanshi*, G. Zhou*, P. Chen*, F. Li*

MeSH headings : Cell Line, Tumor; Copper; Drug Combinations; Immunogenic Cell Death; Infrared Rays; Nanoparticles; Neoplasms / drug therapy; Prodrugs
topics (OpenAlex): Nanoplatforms for cancer theranostics; Adenosine and Purinergic Signaling; Advanced Nanomaterials in Catalysis
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2021 journal article

Short palate, lung, and nasal epithelial clone 1 (SPLUNC1) level determines steroid-resistant airway inflammation in aging

American Journal of Physiology-Lung Cellular and Molecular Physiology, 322(1), L102–L115.

By: A. Jaiswal*, J. Yadav*, S. Makhija*, M. Sandey*, A. Suryawanshi*, A. Mitra*, A. Mishra*

MeSH headings : Aging / pathology; Animals; Antigen Presentation / drug effects; Cell Movement / drug effects; Dendritic Cells / drug effects; Dendritic Cells / pathology; Dermatophagoides pteronyssinus / drug effects; Dexamethasone / pharmacology; Eosinophils / drug effects; Eosinophils / pathology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Glycolysis / drug effects; Glycoproteins / metabolism; Granuloma / pathology; Inflammation / pathology; Lymph Nodes / pathology; Mediastinum / pathology; Models, Biological; Phosphoproteins / metabolism; Respiratory System / parasitology; Respiratory System / pathology; Steroids / pharmacology
topics (OpenAlex): Asthma and respiratory diseases; IL-33, ST2, and ILC Pathways; Eosinophilic Esophagitis
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2020 journal article

Dendritic Cell-Restricted Progenitors Contribute to Obesity-Associated Airway Inflammation via Adam17-p38 MAPK-Dependent Pathway

Frontiers in Immunology, 11.

MeSH headings : ADAM17 Protein / metabolism; Animals; Antigens, Dermatophagoides / immunology; Cells, Cultured; Dendritic Cells / immunology; Diet, High-Fat; Disease Models, Animal; Humans; Hypersensitivity / immunology; Male; Mice; Mice, Inbred C57BL; Obesity / immunology; Pneumonia / immunology; Signal Transduction; Stem Cells / immunology; p38 Mitogen-Activated Protein Kinases / metabolism
topics (OpenAlex): Immune Cell Function and Interaction; Asthma and respiratory diseases; Immunotherapy and Immune Responses
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2020 journal article

Pyruvate kinase M2 in lung APCs regulates Alternaria-induced airway inflammation

Immunobiology, 225(4), 151956.

By: A. Jaiswal*, S. Makhija*, N. Stahr*, M. Sandey*, A. Suryawanshi* & A. Mishra*

MeSH headings : Allergens / immunology; Alternaria / immunology; Alternariosis / metabolism; Alternariosis / microbiology; Animals; Antigen-Presenting Cells / immunology; Antigen-Presenting Cells / metabolism; Asthma / etiology; Asthma / metabolism; Asthma / pathology; Biomarkers; Cytokines / metabolism; Disease Models, Animal; Glucose / metabolism; Glycolysis; Host-Pathogen Interactions / genetics; Host-Pathogen Interactions / immunology; Immunophenotyping; Inflammation Mediators / metabolism; Lung / immunology; Lung / metabolism; Lung / pathology; Mice; Mice, Knockout; Mice, Transgenic; Pyruvate Kinase / genetics; Pyruvate Kinase / metabolism; Reactive Oxygen Species / metabolism; Respiratory Hypersensitivity / metabolism; Respiratory Hypersensitivity / microbiology; Respiratory Hypersensitivity / pathology
topics (OpenAlex): Immune Cell Function and Interaction; Immune cells in cancer; Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2020 journal article

Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity

Frontiers in Immunology, 11.

By: A. Suryawanshi*, M. Hussein*, P. Prasad* & S. Manicassamy*

MeSH headings : Dendritic Cells / immunology; Dendritic Cells / metabolism; Humans; Immunity / immunology; Immunotherapy; Neoplasms / immunology; Signal Transduction / immunology; Tumor Microenvironment / immunology; Tumor Microenvironment / physiology; Wnt Signaling Pathway / immunology; beta Catenin / immunology; beta Catenin / metabolism
topics (OpenAlex): Immunotherapy and Immune Responses; Immune Cell Function and Interaction; Cancer Immunotherapy and Biomarkers
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2019 journal article

Dimethyl fumarate abrogates dust mite‐induced allergic asthma by altering dendritic cell function

Immunity, Inflammation and Disease, 7(3), 201–213.

By: A. Jaiswal*, M. Sandey*, A. Suryawanshi*, R. Cattley* & A. Mishra*

MeSH headings : Administration, Intranasal; Animals; Asthma / immunology; Asthma / therapy; Dendritic Cells / drug effects; Dendritic Cells / immunology; Dimethyl Fumarate / administration & dosage; Dimethyl Fumarate / immunology; Female; Hypersensitivity / immunology; Hypersensitivity / therapy; Lung / drug effects; Lung / immunology; Mice; Pyroglyphidae / immunology; Signal Transduction / drug effects; Signal Transduction / immunology; Th2 Cells / drug effects; Th2 Cells / immunology
topics (OpenAlex): Asthma and respiratory diseases; Allergic Rhinitis and Sensitization; IL-33, ST2, and ILC Pathways
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2018 journal article

GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis

The Journal of Immunology, 200(5), 1781–1789.

By: P. Ranganathan*, A. Shanmugam*, D. Swafford*, A. Suryawanshi*, P. Bhattacharjee*, M. Hussein*, P. Koni*, P. Prasad* ...

MeSH headings : Animals; Colitis / metabolism; Cytokines / metabolism; Disease Models, Animal; Female; Homeostasis / physiology; Lactic Acid / metabolism; Macrophages / metabolism; Male; Mice; Mice, Inbred C57BL; Receptors, Cell Surface / metabolism; Receptors, G-Protein-Coupled / metabolism; Th1 Cells / metabolism
topics (OpenAlex): Helicobacter pylori-related gastroenterology studies; Gastrointestinal motility and disorders; Digestive system and related health; Immune Cell Function and Interaction; IL-33, ST2, and ILC Pathways
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2016 article

Galectin‐8 promotes regulatory T‐cell differentiation by modulating IL‐2 and TGFβ signaling

Sampson, J. F., Suryawanshi, A., Chen, W. S., Rabinovich, G. A., & Panjwani, N. (2016, February 1). Immunology and Cell Biology, Vol. 94, pp. 220–220.

By: J. Sampson, A. Suryawanshi*, W. Chen, G. Rabinovich & N. Panjwani

topics (OpenAlex): Galectins and Cancer Biology
Source: ORCID
Added: July 21, 2024

2016 article

Homeostatic PPARα Signaling Limits Inflammatory Responses to Commensal Microbiota in the Intestine

Manoharan, I., Suryawanshi, A., Hong, Y., Ranganathan, P., Shanmugam, A., Ahmad, S., … Manicassamy, S. (2016, April 26). The Journal of Immunology, Vol. 196, pp. 4739–4749.

By: I. Manoharan*, A. Suryawanshi*, Y. Hong*, P. Ranganathan*, A. Shanmugam*, S. Ahmad*, D. Swafford*, B. Manicassamy* ...

MeSH headings : Animals; Cells, Cultured; Gastrointestinal Microbiome / immunology; Homeodomain Proteins / immunology; Homeostasis; Inflammation / immunology; Inflammation / prevention & control; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR alpha / deficiency; PPAR alpha / metabolism; Signal Transduction
topics (OpenAlex): Gut microbiota and health; Helicobacter pylori-related gastroenterology studies; IL-33, ST2, and ILC Pathways
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2016 journal article

Modulation of Inflammatory Responses by Wnt/β-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer

Frontiers in Immunology, 7.

By: A. Suryawanshi*, R. Tadagavadi*, D. Swafford* & S. Manicassamy*

topics (OpenAlex): Immunotherapy and Immune Responses; Cancer Immunotherapy and Biomarkers
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2016 journal article

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection

PLOS Pathogens, 12(7), e1005754.

By: M. Kandasamy*, A. Suryawanshi*, S. Tundup*, J. Perez*, M. Schmolke*, S. Manicassamy*, B. Manicassamy*

Ed(s): K. Subbarao

MeSH headings : Adaptor Proteins, Signal Transducing / immunology; Animals; Coculture Techniques; Dendritic Cells / immunology; Disease Models, Animal; Flow Cytometry; Influenza A virus / immunology; Interferon Type I / biosynthesis; Interferon Type I / immunology; Lymphocyte Activation / immunology; Membrane Proteins / immunology; Membrane Proteins / metabolism; Mice; Mice, Knockout; Nerve Tissue Proteins / immunology; Nerve Tissue Proteins / metabolism; Orthomyxoviridae Infections / immunology; Polymerase Chain Reaction; Receptors, Cell Surface; Signal Transduction / immunology; T-Lymphocytes / immunology; T-Lymphocytes / metabolism
topics (OpenAlex): interferon and immune responses; Immune Response and Inflammation; Influenza Virus Research Studies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2015 article

Canonical Wnt Signaling in Dendritic Cells Regulates Th1/Th17 Responses and Suppresses Autoimmune Neuroinflammation

Suryawanshi, A., Manoharan, I., Hong, Y., Swafford, D., Majumdar, T., Taketo, M. M., … Manicassamy, S. (2015, February 26). The Journal of Immunology, Vol. 194, pp. 3295–3304.

By: A. Suryawanshi*, I. Manoharan*, Y. Hong*, D. Swafford*, T. Majumdar*, M. Taketo*, B. Manicassamy*, P. Koni* ...

MeSH headings : Animals; Cell Differentiation; Cytokines / metabolism; Dendritic Cells / immunology; Dendritic Cells / metabolism; Encephalomyelitis, Autoimmune, Experimental / immunology; Encephalomyelitis, Autoimmune, Experimental / metabolism; Encephalomyelitis, Autoimmune, Experimental / pathology; Gene Deletion; Gene Knockout Techniques; Inflammation Mediators / metabolism; Interleukin-10 / metabolism; Low Density Lipoprotein Receptor-Related Protein-5 / genetics; Low Density Lipoprotein Receptor-Related Protein-6 / genetics; Male; Mice; Mice, Transgenic; Signal Transduction; T-Lymphocyte Subsets / immunology; T-Lymphocyte Subsets / metabolism; Th1 Cells / cytology; Th1 Cells / immunology; Th1 Cells / metabolism; Th17 Cells / cytology; Th17 Cells / immunology; Th17 Cells / metabolism; Transforming Growth Factor beta / metabolism; Wnt Signaling Pathway / drug effects; Wnt3A Protein / metabolism; beta Catenin / metabolism
topics (OpenAlex): Galectins and Cancer Biology; Immunotherapy and Immune Responses
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2015 article

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

Hong, Y., Manoharan, I., Suryawanshi, A., Shanmugam, A., Swafford, D., Ahmad, S., … Manicassamy, S. (2015, December 14). OncoImmunology, Vol. 5, p. e1115941.

By: Y. Hong*, I. Manoharan*, A. Suryawanshi*, A. Shanmugam*, D. Swafford*, S. Ahmad*, R. Chinnadurai*, B. Manicassamy* ...

topics (OpenAlex): Immunotherapy and Immune Responses; Galectins and Cancer Biology
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2015 article

Galectin-8 Ameliorates Murine Autoimmune Ocular Pathology and Promotes a Regulatory T Cell Response

Sampson, J. F., Hasegawa, E., Mulki, L., Suryawanshi, A., Jiang, S., Chen, W.-S., … Panjwani, N. (2015, June 30). (H. M. Ashour, Ed.). PLoS ONE, Vol. 10, p. e0130772.

By: J. Sampson*, E. Hasegawa*, L. Mulki*, A. Suryawanshi*, S. Jiang*, W. Chen*, G. Rabinovich*, K. Connor*, N. Panjwani*

Ed(s): H. Ashour

MeSH headings : Animals; Antigens, CD / immunology; Autoimmune Diseases / immunology; CTLA-4 Antigen / immunology; Cell Differentiation / immunology; Disease Models, Animal; Galectins / immunology; Immunosuppressive Agents / immunology; Inflammation / immunology; Integrin alpha Chains / immunology; Interleukin-10 / immunology; Lymph Nodes / immunology; Mice; Neuropilin-1 / immunology; T-Lymphocytes, Regulatory / immunology; Th1 Cells / immunology; Th17 Cells / immunology; Uveitis / immunology
topics (OpenAlex): Galectins and Cancer Biology; Protein Tyrosine Phosphatases; Bioactive Compounds and Antitumor Agents
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2015 article

Tumors induce immune tolerance through activation of β-catenin/TCF4 signaling in dendritic cells: A novel therapeutic target for cancer immunotherapy

Suryawanshi, A., & Manicassamy, S. (2015, June 26). OncoImmunology, Vol. 4, p. e1052932.

By: A. Suryawanshi* & S. Manicassamy*

topics (OpenAlex): Immunotherapy and Immune Responses; Cancer-related gene regulation
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2015 journal article

β-Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells

Cancer Research, 75(4), 656–665.

By: Y. Hong*, I. Manoharan*, A. Suryawanshi*, T. Majumdar*, M. Angus-Hill*, P. Koni*, B. Manicassamy*, A. Mellor*, D. Munn*, S. Manicassamy*

MeSH headings : Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / immunology; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / metabolism; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; Dendritic Cells / metabolism; Dendritic Cells / pathology; Humans; Mice; Mice, Transgenic; Signal Transduction; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism; Transcription Factor 4; Tumor Microenvironment / genetics; Tumor Microenvironment / immunology; Vitamin A / metabolism; beta Catenin / genetics; beta Catenin / metabolism
topics (OpenAlex): Immunotherapy and Immune Responses; Immune Cell Function and Interaction; Cancer Immunotherapy and Biomarkers
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 22, 2024

2014 article

An Approach to Control Relapse of Inflammatory Lesions after Discontinuation of Primary Therapy

Reddy, P. B. J., Sehrawat, S., Suryawanshi, A., Rajasagi, N. K., Khatri, M., & Rouse, B. T. (2014, May 20). (R. Tripp, Ed.). PLoS ONE, Vol. 9, p. e98051.

By: P. Reddy*, S. Sehrawat*, A. Suryawanshi*, N. Rajasagi*, M. Khatri* & B. Rouse*

Ed(s): R. Tripp

MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Monoclonal / pharmacology; Antibodies, Neutralizing / administration & dosage; Antibodies, Neutralizing / pharmacology; Cell Differentiation; Disease Models, Animal; Female; Fingolimod Hydrochloride; Herpesvirus 1, Human / immunology; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / pharmacology; Interleukin-6 / antagonists & inhibitors; Interleukin-6 / immunology; Keratitis, Herpetic / drug therapy; Keratitis, Herpetic / immunology; Keratitis, Herpetic / pathology; Keratitis, Herpetic / prevention & control; Keratitis, Herpetic / virology; Mice; Mice, Knockout; Propylene Glycols / administration & dosage; Propylene Glycols / pharmacology; Receptors, Lysosphingolipid / metabolism; Recurrence; Secondary Prevention; Sphingosine / administration & dosage; Sphingosine / analogs & derivatives; Sphingosine / pharmacology; T-Lymphocyte Subsets / cytology; T-Lymphocyte Subsets / immunology; T-Lymphocyte Subsets / metabolism
topics (OpenAlex): Sphingolipid Metabolism and Signaling; Inflammasome and immune disorders; Ocular Surface and Contact Lens
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2014 article

IL-17A–Mediated Protection against Acanthamoeba Keratitis

Suryawanshi, A., Cao, Z., Sampson, J. F., & Panjwani, N. (2014, December 11). The Journal of Immunology, Vol. 194, pp. 650–663.

By: A. Suryawanshi*, Z. Cao*, J. Sampson* & N. Panjwani*

MeSH headings : Acanthamoeba / immunology; Acanthamoeba Keratitis / genetics; Acanthamoeba Keratitis / immunology; Acanthamoeba Keratitis / pathology; Animals; Cornea / immunology; Cornea / parasitology; Cornea / pathology; Disease Models, Animal; Female; Immunity, Cellular; Interleukin-17 / genetics; Interleukin-17 / immunology; Lymph Nodes / immunology; Lymph Nodes / pathology; Mice; Mice, Knockout; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / pathology; Th17 Cells / immunology; Th17 Cells / pathology
topics (OpenAlex): Legionella and Acanthamoeba research; Heme Oxygenase-1 and Carbon Monoxide; Ocular Surface and Contact Lens
Source: ORCID
Added: July 21, 2024

2014 article

TLR2-Dependent Activation of β-Catenin Pathway in Dendritic Cells Induces Regulatory Responses and Attenuates Autoimmune Inflammation

Manoharan, I., Hong, Y., Suryawanshi, A., Angus-Hill, M. L., Sun, Z., Mellor, A. L., … Manicassamy, S. (2014, September 11). The Journal of Immunology, Vol. 193, pp. 4203–4213.

By: I. Manoharan*, Y. Hong*, A. Suryawanshi*, M. Angus-Hill*, Z. Sun*, A. Mellor*, D. Munn*, S. Manicassamy*

MeSH headings : Adoptive Transfer; Aldehyde Dehydrogenase / biosynthesis; Aldehyde Dehydrogenase 1 Family; Animals; Autoimmunity / immunology; Cell Differentiation / immunology; Dendritic Cells / immunology; Encephalomyelitis, Autoimmune, Experimental / chemically induced; Encephalomyelitis, Autoimmune, Experimental / immunology; Inflammation / immunology; Inflammation / prevention & control; Interleukin-10 / biosynthesis; Lectins, C-Type / immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins c-akt / immunology; Retinal Dehydrogenase; T-Lymphocytes, Regulatory / cytology; Th1 Cells / cytology; Th1 Cells / immunology; Th17 Cells / cytology; Th17 Cells / immunology; Toll-Like Receptor 2 / immunology; Transcription Factor 7-Like 2 Protein / immunology; Zymosan / immunology; Zymosan / pharmacology; beta Catenin / genetics; beta Catenin / metabolism
topics (OpenAlex): Immune Response and Inflammation; Immunotherapy and Immune Responses; Antimicrobial Peptides and Activities
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2013 journal article

Galectin-1–Mediated Suppression of Pseudomonas aeruginosa–Induced Corneal Immunopathology

The Journal of Immunology, 190(12), 6397–6409.

By: A. Suryawanshi*, Z. Cao*, T. Thitiprasert*, T. Zaidi* & N. Panjwani*

MeSH headings : Animals; Cornea / immunology; Cornea / microbiology; Cornea / pathology; Enzyme-Linked Immunosorbent Assay; Eye Infections, Bacterial / immunology; Eye Infections, Bacterial / metabolism; Eye Infections, Bacterial / pathology; Flow Cytometry; Galectin 1 / immunology; Galectin 1 / metabolism; Keratitis / immunology; Keratitis / microbiology; Keratitis / pathology; Mice; Mice, Inbred C57BL; Pseudomonas Infections / immunology; Pseudomonas Infections / metabolism; Pseudomonas Infections / pathology; Pseudomonas aeruginosa; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism; Th1 Cells / immunology; Th1 Cells / metabolism; Th17 Cells / immunology; Th17 Cells / metabolism
topics (OpenAlex): Galectins and Cancer Biology; Toxin Mechanisms and Immunotoxins; Invertebrate Immune Response Mechanisms
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2012 journal article

Galectin-1 Reduces the Severity of Herpes Simplex Virus-Induced Ocular Immunopathological Lesions

The Journal of Immunology, 188(9), 4631–4643.

By: N. Rajasagi*, A. Suryawanshi*, S. Sehrawat*, P. Reddy*, S. Mulik*, M. Hirashima*, B. Rouse*

MeSH headings : Animals; Blindness / genetics; Blindness / immunology; Blindness / metabolism; Blindness / pathology; Blindness / virology; Corneal Neovascularization / genetics; Corneal Neovascularization / immunology; Corneal Neovascularization / metabolism; Corneal Neovascularization / pathology; Corneal Neovascularization / virology; Galectin 1 / genetics; Galectin 1 / immunology; Galectin 1 / metabolism; Herpesvirus 1, Human / genetics; Herpesvirus 1, Human / immunology; Herpesvirus 1, Human / metabolism; Interleukin-10 / genetics; Interleukin-10 / immunology; Interleukin-10 / metabolism; Keratitis, Herpetic / genetics; Keratitis, Herpetic / immunology; Keratitis, Herpetic / metabolism; Keratitis, Herpetic / pathology; Mice; Mice, Knockout; Th1 Cells / immunology; Th1 Cells / metabolism; Th1 Cells / pathology; Th17 Cells / immunology; Th17 Cells / metabolism; Th17 Cells / pathology
topics (OpenAlex): Galectins and Cancer Biology; Toxin Mechanisms and Immunotoxins; Invertebrate Immune Response Mechanisms
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2012 journal article

IL-17A Differentially Regulates Corneal Vascular Endothelial Growth Factor (VEGF)-A and Soluble VEGF Receptor 1 Expression and Promotes Corneal Angiogenesis after Herpes Simplex Virus Infection

The Journal of Immunology, 188(7), 3434–3446.

By: A. Suryawanshi*, T. Veiga-Parga*, P. Reddy*, N. Rajasagi* & B. Rouse*

MeSH headings : Animals; Chemokine CXCL1 / biosynthesis; Chemokine CXCL1 / genetics; Chemotaxis, Leukocyte / physiology; Cornea / metabolism; Corneal Neovascularization / etiology; Corneal Neovascularization / genetics; Corneal Neovascularization / physiopathology; Cytokines / biosynthesis; Cytokines / genetics; Enzyme Induction; Fibroblasts / metabolism; Gene Expression Regulation; Interleukin-17 / deficiency; Interleukin-17 / genetics; Interleukin-17 / physiology; Interleukin-6 / biosynthesis; Interleukin-6 / genetics; Keratitis, Herpetic / complications; Matrix Metalloproteinases / biosynthesis; Matrix Metalloproteinases / genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils / physiology; Signal Transduction; Stromal Cells / metabolism; Vascular Endothelial Growth Factor A / biosynthesis; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor Receptor-1 / biosynthesis; Vascular Endothelial Growth Factor Receptor-1 / genetics
topics (OpenAlex): Ocular Surface and Contact Lens; Corneal Surgery and Treatments; Immune Response and Inflammation
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2012 journal article

On the Role of Regulatory T Cells during Viral-Induced Inflammatory Lesions

The Journal of Immunology, 189(12), 5924–5933.

By: T. Veiga-Parga*, A. Suryawanshi*, S. Mulik*, F. Giménez*, S. Sharma*, T. Sparwasser*, B. Rouse*

MeSH headings : Animals; Forkhead Transcription Factors / genetics; Genes, Reporter / immunology; Herpesvirus 1, Human / immunology; Inflammation / genetics; Inflammation / immunology; Inflammation / virology; Keratitis, Herpetic / genetics; Keratitis, Herpetic / immunology; Keratitis, Herpetic / pathology; Lymph Nodes; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / pathology; T-Lymphocytes, Regulatory / virology; Th1 Cells / immunology; Th1 Cells / pathology; Th1 Cells / virology
topics (OpenAlex): T-cell and B-cell Immunology; Immune Cell Function and Interaction; Cancer Immunotherapy and Biomarkers
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2012 article

Pathogenesis of herpes stromal keratitis – A focus on corneal neovascularization

Giménez, F., Suryawanshi, A., & Rouse, B. T. (2012, August 7). Progress in Retinal and Eye Research, Vol. 33, pp. 1–9.

By: F. Giménez*, A. Suryawanshi* & B. Rouse*

MeSH headings : Angiogenesis Inhibitors / therapeutic use; Animals; Corneal Neovascularization / complications; Corneal Neovascularization / drug therapy; Corneal Neovascularization / immunology; Disease Models, Animal; Humans; Keratitis, Herpetic / drug therapy; Keratitis, Herpetic / etiology; Vascular Endothelial Growth Factor A / antagonists & inhibitors; Vascular Endothelial Growth Factor A / physiology
topics (OpenAlex): Ocular Surface and Contact Lens; Corneal Surgery and Treatments; Herpesvirus Infections and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2012 journal article

TNFRSF25 Agonistic Antibody and Galectin-9 Combination Therapy Controls Herpes Simplex Virus-Induced Immunoinflammatory Lesions

Journal of Virology, 86(19), 10606–10620.

MeSH headings : Animals; Antibodies / chemistry; Antibodies, Monoclonal / chemistry; Antigens, CD / biosynthesis; Apoptosis; CD4-Positive T-Lymphocytes / metabolism; Cell Proliferation; Cornea / virology; Cricetinae; Female; Forkhead Transcription Factors / metabolism; Galectins / metabolism; Green Fluorescent Proteins / metabolism; Herpes Simplex / metabolism; Inflammation; Integrin alpha Chains / biosynthesis; Keratitis, Herpetic / immunology; Keratitis, Herpetic / virology; Kinetics; Mice; Mice, Inbred C57BL; Receptors, Tumor Necrosis Factor, Member 25 / immunology; Receptors, Tumor Necrosis Factor, Member 25 / metabolism; Simplexvirus / metabolism
topics (OpenAlex): Galectins and Cancer Biology; Toxin Mechanisms and Immunotoxins; Immune Cell Function and Interaction
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2011 journal article

Activation of Endothelial Roundabout Receptor 4 Reduces the Severity of Virus-Induced Keratitis

The Journal of Immunology, 186(12), 7195–7204.

By: S. Mulik*, S. Sharma*, A. Suryawanshi*, T. Veiga-Parga*, P. Reddy*, N. Rajasagi*, B. Rouse*

MeSH headings : ADP-Ribosylation Factor 6; Animals; Eye Infections / virology; Female; Herpes Simplex; Keratitis / pathology; Keratitis / virology; Mice; Neovascularization, Pathologic; Nerve Tissue Proteins / metabolism; Protective Agents; Receptors, Cell Surface / genetics; Receptors, Cell Surface / metabolism; Receptors, Immunologic / metabolism; Simplexvirus; Up-Regulation
topics (OpenAlex): Axon Guidance and Neuronal Signaling; Angiogenesis and VEGF in Cancer; Hippo pathway signaling and YAP/TAZ
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2011 journal article

An Anti-Inflammatory Role of VEGFR2/Src Kinase Inhibitor in Herpes Simplex Virus 1-Induced Immunopathology

Journal of Virology, 85(12), 5995–6007.

By: S. Sharma*, S. Mulik*, N. Kumar*, A. Suryawanshi* & B. Rouse*

MeSH headings : Angiogenesis Inhibitors / administration & dosage; Angiogenesis Inhibitors / therapeutic use; Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Monoclonal / therapeutic use; Antibodies, Monoclonal, Humanized; Bevacizumab; Cornea / blood supply; Cornea / metabolism; Cornea / pathology; Female; Herpesvirus 1, Human / drug effects; Herpesvirus 1, Human / immunology; Herpesvirus 1, Human / pathogenicity; Keratitis, Herpetic / drug therapy; Keratitis, Herpetic / immunology; Keratitis, Herpetic / pathology; Keratitis, Herpetic / virology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neovascularization, Pathologic / drug therapy; Phenols / administration & dosage; Phenols / therapeutic use; Treatment Outcome; Triazines / administration & dosage; Triazines / therapeutic use; Vascular Endothelial Growth Factor Receptor-2 / antagonists & inhibitors; src-Family Kinases / antagonists & inhibitors
topics (OpenAlex): Ocular Infections and Treatments; Herpesvirus Infections and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2011 article

Controlling Viral Immuno-Inflammatory Lesions by Modulating Aryl Hydrocarbon Receptor Signaling

Veiga-Parga, T., Suryawanshi, A., & Rouse, B. T. (2011, December 8). (E. J. Wherry, Ed.). PLoS Pathogens, Vol. 7, p. e1002427.

By: T. Veiga-Parga*, A. Suryawanshi* & B. Rouse*

Ed(s): E. Wherry

MeSH headings : Animals; CD4-Positive T-Lymphocytes / cytology; CD4-Positive T-Lymphocytes / drug effects; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; Cell Differentiation / drug effects; Cell Differentiation / immunology; Cell Separation; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Forkhead Transcription Factors / immunology; Forkhead Transcription Factors / metabolism; Herpesvirus 1, Human / immunology; Immunosuppressive Agents / pharmacology; Inflammation / immunology; Inflammation / metabolism; Keratitis, Herpetic / immunology; Keratitis, Herpetic / metabolism; Keratitis, Herpetic / pathology; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins / pharmacology; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon / agonists; Receptors, Aryl Hydrocarbon / immunology; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction / drug effects; T-Lymphocyte Subsets / cytology; T-Lymphocyte Subsets / drug effects; T-Lymphocyte Subsets / immunology
topics (OpenAlex): Immune Response and Inflammation; Ocular Surface and Contact Lens
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 21, 2024

2011 journal article

Influence of Galectin-9/Tim-3 Interaction on Herpes Simplex Virus-1 Latency

The Journal of Immunology, 187(11), 5745–5755.

By: P. Reddy*, S. Sehrawat*, A. Suryawanshi*, N. Rajasagi*, S. Mulik*, M. Hirashima*, B. Rouse*

MeSH headings : Animals; Apoptosis / immunology; Blotting, Western; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / virology; Cell Separation; Female; Flow Cytometry; Fluorescent Antibody Technique; Galectins / immunology; Hepatitis A Virus Cellular Receptor 2; Herpes Simplex / immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Real-Time Polymerase Chain Reaction; Receptors, Virus / immunology; Reverse Transcriptase Polymerase Chain Reaction; Simplexvirus / physiology; Trigeminal Ganglion / immunology; Trigeminal Ganglion / virology; Virus Latency / immunology
topics (OpenAlex): Galectins and Cancer Biology; Toxin Mechanisms and Immunotoxins; Immune Cell Function and Interaction
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2011 journal article

Ocular Neovascularization Caused by Herpes Simplex Virus Type 1 Infection Results from Breakdown of Binding between Vascular Endothelial Growth Factor A and Its Soluble Receptor

The Journal of Immunology, 186(6), 3653–3665.

MeSH headings : Animals; Cell Line, Transformed; Corneal Neovascularization / immunology; Corneal Neovascularization / metabolism; Corneal Neovascularization / virology; Female; Herpes Simplex / immunology; Herpes Simplex / metabolism; Herpes Simplex / virology; Herpesvirus 1, Human / immunology; Mice; Mice, Inbred C57BL; Protein Binding / immunology; Random Allocation; Vascular Endothelial Growth Factor A / antagonists & inhibitors; Vascular Endothelial Growth Factor A / biosynthesis; Vascular Endothelial Growth Factor A / metabolism; Vascular Endothelial Growth Factor Receptor-1 / antagonists & inhibitors; Vascular Endothelial Growth Factor Receptor-1 / metabolism
topics (OpenAlex): Retinal Diseases and Treatments; Corneal Surgery and Treatments; Ocular Infections and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2011 journal article

Role of IL-17 and Th17 Cells in Herpes Simplex Virus-Induced Corneal Immunopathology

The Journal of Immunology, 187(4), 1919–1930.

By: A. Suryawanshi*, T. Veiga-Parga*, N. Rajasagi*, P. Reddy*, S. Sehrawat*, S. Sharma*, B. Rouse*

MeSH headings : Animals; Chemokines / genetics; Chemokines / immunology; Chemokines / metabolism; Interferon-gamma / genetics; Interferon-gamma / immunology; Interferon-gamma / metabolism; Interleukin-17 / genetics; Interleukin-17 / immunology; Interleukin-17 / metabolism; Keratitis, Herpetic / genetics; Keratitis, Herpetic / immunology; Keratitis, Herpetic / metabolism; Mice; Mice, Knockout; Receptors, Antigen, T-Cell, gamma-delta / genetics; Receptors, Antigen, T-Cell, gamma-delta / immunology; Receptors, Antigen, T-Cell, gamma-delta / metabolism; Simplexvirus / genetics; Simplexvirus / immunology; Simplexvirus / metabolism; Th1 Cells / immunology; Th1 Cells / metabolism; Th17 Cells / immunology; Th17 Cells / metabolism; Time Factors; Up-Regulation / genetics; Up-Regulation / immunology
topics (OpenAlex): Immune Response and Inflammation; Ocular Surface and Contact Lens; Psoriasis: Treatment and Pathogenesis
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2011 journal article

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses

Proceedings of the National Academy of Sciences, 108(47), 19001–19006.

MeSH headings : Acute-Phase Reaction / immunology; Analysis of Variance; Animals; CD8-Positive T-Lymphocytes / immunology; Enzyme-Linked Immunosorbent Assay; Female; Galectins / genetics; Galectins / immunology; Hepatitis A Virus Cellular Receptor 2; Immunity, Humoral / immunology; Influenza A virus / immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Orthomyxoviridae Infections / immunology; Receptors, Virus / immunology; Signal Transduction / immunology
topics (OpenAlex): Galectins and Cancer Biology; Toxin Mechanisms and Immunotoxins; Immune Cell Function and Interaction
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2010 journal article

Controlling Herpes Simplex Virus-Induced Ocular Inflammatory Lesions with the Lipid-Derived Mediator Resolvin E1

The Journal of Immunology, 186(3), 1735–1746.

By: N. Rajasagi*, P. Reddy*, A. Suryawanshi*, S. Mulik*, P. Gjorstrup* & B. Rouse*

MeSH headings : Administration, Topical; Angiogenesis Inhibitors / administration & dosage; Animals; Antiviral Agents / administration & dosage; CD4-Positive T-Lymphocytes / drug effects; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / pathology; Cell Movement / drug effects; Cell Movement / immunology; Cornea / blood supply; Cornea / drug effects; Disease Models, Animal; Eicosapentaenoic Acid / administration & dosage; Eicosapentaenoic Acid / analogs & derivatives; Female; Herpesvirus 1, Human / drug effects; Herpesvirus 1, Human / immunology; Humans; Inflammation Mediators / administration & dosage; Keratitis, Herpetic / immunology; Keratitis, Herpetic / prevention & control; Keratitis, Herpetic / virology; Mice; Mice, Inbred BALB C; Neutrophils / drug effects; Neutrophils / immunology; Neutrophils / pathology
topics (OpenAlex): Immune Response and Inflammation; Cholesterol and Lipid Metabolism; Fatty Acid Research and Health
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2010 article

Galectin-9/TIM-3 Interaction Regulates Virus-Specific Primary and Memory CD8+ T Cell Response

Sehrawat, S., Reddy, P. B. J., Rajasagi, N. K., Suryawanshi, A., Hirashima, M., & Rouse, B. T. (2010, May 6). (A. B. Hill, Ed.). PLoS Pathogens, Vol. 6, p. e1000882.

By: S. Sehrawat*, P. Reddy*, N. Rajasagi*, A. Suryawanshi*, M. Hirashima* & B. Rouse*

Ed(s): A. Hill

MeSH headings : Acute-Phase Reaction / immunology; Acute-Phase Reaction / virology; Animals; Apoptosis / immunology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; CD8-Positive T-Lymphocytes / virology; Female; Forkhead Transcription Factors / metabolism; Galectins / genetics; Galectins / metabolism; Hepatitis A Virus Cellular Receptor 2; Herpes Simplex / immunology; Herpes Simplex / metabolism; Immunologic Memory / immunology; Lactose / immunology; Lactose / metabolism; Lactose / pharmacology; Lymphoid Tissue / immunology; Lymphoid Tissue / virology; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Virus / metabolism; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism; T-Lymphocytes, Regulatory / virology; Up-Regulation / immunology; Viral Load / immunology; Viral Vaccines
topics (OpenAlex): Galectins and Cancer Biology; Toxin Mechanisms and Immunotoxins; Signaling Pathways in Disease
Source: ORCID
Added: July 21, 2024

2009 journal article

Mapping the complement C1q binding site in Haemonchus contortus calreticulin

Molecular and Biochemical Parasitology, 166(1), 42–46.

By: S. Naresha*, A. Suryawanshi*, M. Agarwal*, B. Singh* & P. Joshi*

MeSH headings : Animals; Binding Sites; Calreticulin / chemistry; Calreticulin / metabolism; Complement C1q / metabolism; Erythrocytes / immunology; Gene Expression Regulation; Haemonchus / chemistry; Haemonchus / genetics; Haemonchus / metabolism; Helminth Proteins / chemistry; Helminth Proteins / immunology; Hemolysis / physiology; Humans; Protein Binding; Recombinant Proteins / immunology; Recombinant Proteins / metabolism; Sheep
topics (OpenAlex): Complement system in diseases; Parasites and Host Interactions; Malaria Research and Control
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2009 journal article

Role of Tim-3/Galectin-9 Inhibitory Interaction in Viral-Induced Immunopathology: Shifting the Balance toward Regulators

The Journal of Immunology, 182(5), 3191–3201.

By: S. Sehrawat*, A. Suryawanshi*, M. Hirashima* & B. Rouse*

MeSH headings : Animals; Apoptosis / immunology; Cells, Cultured; Chlorocebus aethiops; Corneal Neovascularization / immunology; Corneal Neovascularization / pathology; Corneal Neovascularization / virology; Female; Galectins / metabolism; Galectins / physiology; Gene Knock-In Techniques; Hepatitis A Virus Cellular Receptor 2; Herpesvirus 1, Human / immunology; Keratitis, Herpetic / immunology; Keratitis, Herpetic / pathology; Keratitis, Herpetic / virology; Lymphocyte Activation / immunology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Receptors, Virus / biosynthesis; Receptors, Virus / deficiency; Receptors, Virus / physiology; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism; T-Lymphocytes, Regulatory / pathology; T-Lymphocytes, Regulatory / virology; Vascular Endothelial Growth Factor A / antagonists & inhibitors; Vascular Endothelial Growth Factor A / biosynthesis; Vascular Endothelial Growth Factor A / physiology; Vero Cells
topics (OpenAlex): Galectins and Cancer Biology; Toxin Mechanisms and Immunotoxins; Peptidase Inhibition and Analysis
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

2008 journal article

In Vitro-Generated Antigen-Specific CD4+CD25+Foxp3+Regulatory T Cells Control the Severity of Herpes Simplex Virus-Induced Ocular Immunoinflammatory Lesions

Journal of Virology, 82(14), 6838–6851.

MeSH headings : Adoptive Transfer; Animals; CD11c Antigen / analysis; CD4-Positive T-Lymphocytes / immunology; Dendritic Cells / immunology; Flow Cytometry; Forkhead Transcription Factors / analysis; Herpes Simplex / immunology; Immunosuppression Therapy / methods; Immunotherapy, Adoptive / methods; Interleukin-2 Receptor alpha Subunit / analysis; Keratitis, Herpetic / immunology; Keratitis, Herpetic / therapy; Keratitis, Herpetic / virology; Mice; Mice, Inbred BALB C; Mice, Knockout; Simplexvirus / immunology; T-Lymphocyte Subsets / immunology; T-Lymphocytes, Regulatory / immunology; Transforming Growth Factor beta / immunology
topics (OpenAlex): Immunotherapy and Immune Responses; T-cell and B-cell Immunology; Immune Response and Inflammation
Sources: ORCID, Crossref, NC State University Libraries
Added: July 21, 2024

Employment

Updated: July 21st, 2024 12:45

2024 - present

North Carolina State University Raleigh, US
Associate Professor Population Health & Pathobiology

2018 - 2024

Auburn University College of Veterinary Medicine Auburn, AL, US
Assistant Professor Pathobiology

2015 - 2018

AbbVie Inc North Chicago, IL, US
Senior Scientist Foundational Immunology

2014 - 2015

Augusta University Augusta, GA, US
Post-Doctoral Research Fellow Cancer Immunotherapy Center

2012 - 2014

Tufts Medical Center Boston, MA, US
Post-Doctoral Research Scholar Ophthalmology

2011 - 2012

Emory University Vaccine Center Atlanta, GA, US
Post-Doctoral Fellow Pathology

Education

Updated: July 21st, 2024 12:45

2007 - 2011

College of Veterinary Medicine, University of Tennessee TN, TN, US
PhD Pathobiology

2005 - 2007

Indian Veterinary Research Institute Izatnagar, Uttar Pradesh, IN
MVSc Biochemistry

2000 - 2005

Mumbai Veterinary College Mumbai, Maharashtra, IN
DVM Veterinary Medicine

Funding History

Funding history based on the linked ORCID record. Updated: August 17th, 2024 13:14

grant September 30, 2023 - April 30, 2028
IL-27-mediated immunoregulation in HSV-1-induced stromal keratitis
National Eye Institute
grant May 1, 2023 - April 30, 2026
Targeting anti-viral and anti-inflammatory responses during ocular HSV-1 infection to prevent vision impairment.
National Eye Institute
grant February 10, 2021 - January 31, 2024
Th1/Th17 Immune Regulation in Severe Allergic Asthma
National Institute of Allergy and Infectious Diseases

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