Amol Suryawanshi

Akinsipe, T., Mohamedelhassan, R., Akinpelu, A., Pondugula, S. R., Mistriotis, P., Avila, L. A., & Suryawanshi, A. (2024). Cellular interactions in tumor microenvironment during breast cancer progression: new frontiers and implications for novel therapeutics. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1302587

Alrbyawi, H., Annaji, M., Fasina, O., Palakurthi, S., Boddu, S. H. S., Hassan, N., … Babu, R. J. (2024). Rapidly Dissolving Trans-scleral Microneedles for Intraocular Delivery of Cyclosporine A. AAPS PharmSciTech, 25(2). https://doi.org/10.1208/s12249-024-02738-5

Antony, F., Pundkar, C., Sandey, M., Mishra, A., & Suryawanshi, A. (2023). Role of IL-27 in HSV-1–Induced Herpetic Stromal Keratitis. The Journal of Immunology, 211(3), 474–485. https://doi.org/10.4049/jimmunol.2200420

Ren, J., Antony, F., Rouse, B. T., & Suryawanshi, A. (2023). Role of Innate Interferon Responses at the Ocular Surface in Herpes Simplex Virus-1-Induced Herpetic Stromal Keratitis. Pathogens, 12(3), 437. https://doi.org/10.3390/pathogens12030437

Pundkar, C., Antony, F., Kang, X., Mishra, A., Babu, R. J., Chen, P., … Suryawanshi, A. (2023). Targeting β-catenin signaling using XAV939 nanoparticles in tumor microenvironment-conditioned macrophages promote immunogenicity. Heliyon, 9(6), e16688. https://doi.org/10.1016/j.heliyon.2023.e16688

Antony, F., Kang, X., Pundkar, C., Wang, C., Mishra, A., Chen, P., … Suryawanshi, A. (2023). Targeting β-catenin using XAV939 nanoparticle promotes immunogenic cell death and suppresses conjunctival melanoma progression. International Journal of Pharmaceutics, 640, 123043. https://doi.org/10.1016/j.ijpharm.2023.123043

Ruiz, D., Haynes, C., Marable, J., Pundkar, C., Nance, R. L., Bedi, D., … Sandey, M. (2022). Development of OX40 agonists for canine cancer immunotherapy. IScience, 25(10), 105158. https://doi.org/10.1016/j.isci.2022.105158

Das, S., Ahmad, Z., Suryawanshi, A., & Kumar, A. (2022). Innate immunity dysregulation in aging eye and therapeutic interventions. Ageing Research Reviews, 82, 101768. https://doi.org/10.1016/j.arr.2022.101768

Jaiswal, A. K., Yadav, J., Makhija, S., Mazumder, S., Mitra, A. K., Suryawanshi, A., … Mishra, A. (2022). Irg1/itaconate metabolic pathway is a crucial determinant of dendritic cells immune-priming function and contributes to resolute allergen-induced airway inflammation. Mucosal Immunology, 15(2), 301–313. https://doi.org/10.1038/s41385-021-00462-y

Jaiswal, A. K., Yadav, J., Makhija, S., Sandey, M., Suryawanshi, A., Mitra, A. K., & Mishra, A. (2022). Short palate, lung, and nasal epithelial clone 1 (SPLUNC1) level determines steroid-resistant airway inflammation in aging. American Journal of Physiology-Lung Cellular and Molecular Physiology, 322(1), L102–L115. https://doi.org/10.1152/ajplung.00315.2021

Antony, F., Pundkar, C., Sandey, M., Jaiswal, A. K., Mishra, A., Kumar, A., … Suryawanshi, A. (2021). IFN-λ Regulates Neutrophil Biology to Suppress Inflammation in Herpes Simplex Virus-1–Induced Corneal Immunopathology. The Journal of Immunology, 206(8), 1866–1877. https://doi.org/10.4049/jimmunol.2000979

Marable, J., Ruiz, D., Jaiswal, A. K., Bhattacharya, R., Pantazes, R., Agarwal, P., … Sandey, M. (2021). Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-00325-3

Kang, X., Cai, Y., Wang, Q., Wang, C., Chen, W., Yang, W., … Li, F. (2021). Near-infrared light triggered activation of pro-drug combination cancer therapy and induction of immunogenic cell death. International Journal of Pharmaceutics, 607, 120972. https://doi.org/10.1016/j.ijpharm.2021.120972

Jaiswal, A. K., Makhija, S., Stahr, N., Sandey, M., Suryawanshi, A., Saxena, A., … Mishra, A. (2020). Dendritic Cell-Restricted Progenitors Contribute to Obesity-Associated Airway Inflammation via Adam17-p38 MAPK-Dependent Pathway. Frontiers in Immunology, 11. https://doi.org/10.3389/fimmu.2020.00363

Jaiswal, A. K., Makhija, S., Stahr, N., Sandey, M., Suryawanshi, A., & Mishra, A. (2020). Pyruvate kinase M2 in lung APCs regulates Alternaria-induced airway inflammation. Immunobiology, 225(4), 151956. https://doi.org/10.1016/j.imbio.2020.151956

Suryawanshi, A., Hussein, M. S., Prasad, P. D., & Manicassamy, S. (2020). Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity. Frontiers in Immunology, 11. https://doi.org/10.3389/fimmu.2020.00122

Jaiswal, A. K., Sandey, M., Suryawanshi, A., Cattley, R. C., & Mishra, A. (2019). Dimethyl fumarate abrogates dust mite‐induced allergic asthma by altering dendritic cell function. Immunity, Inflammation and Disease, 7(3), 201–213. https://doi.org/10.1002/iid3.262

Ranganathan, P., Shanmugam, A., Swafford, D., Suryawanshi, A., Bhattacharjee, P., Hussein, M. S., … Manicassamy, S. (2018). GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis. The Journal of Immunology, 200(5), 1781–1789. https://doi.org/10.4049/jimmunol.1700604

Sampson, J. F., Suryawanshi, A., Chen, W.-S., Rabinovich, G. A., & Panjwani, N. (2016). Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling. Immunology and Cell Biology, 94(2), 220–220. https://doi.org/10.1038/icb.2016.8

Manoharan, I., Suryawanshi, A., Hong, Y., Ranganathan, P., Shanmugam, A., Ahmad, S., … Manicassamy, S. (2016). Homeostatic PPARα Signaling Limits Inflammatory Responses to Commensal Microbiota in the Intestine. The Journal of Immunology, 196(11), 4739–4749. https://doi.org/10.4049/jimmunol.1501489

Suryawanshi, A., Tadagavadi, R. K., Swafford, D., & Manicassamy, S. (2016). Modulation of Inflammatory Responses by Wnt/β-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer. Frontiers in Immunology, 7. https://doi.org/10.3389/fimmu.2016.00460

Kandasamy, M., Suryawanshi, A., Tundup, S., Perez, J. T., Schmolke, M., Manicassamy, S., & Manicassamy, B. (2016). RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection. PLOS Pathogens, 12(7), e1005754. https://doi.org/10.1371/journal.ppat.1005754

Suryawanshi, A., Manoharan, I., Hong, Y., Swafford, D., Majumdar, T., Taketo, M. M., … Manicassamy, S. (2015). Canonical Wnt Signaling in Dendritic Cells Regulates Th1/Th17 Responses and Suppresses Autoimmune Neuroinflammation. The Journal of Immunology, 194(7), 3295–3304. https://doi.org/10.4049/jimmunol.1402691

Hong, Y., Manoharan, I., Suryawanshi, A., Shanmugam, A., Swafford, D., Ahmad, S., … Manicassamy, S. (2015). Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity. OncoImmunology, 5(4), e1115941. https://doi.org/10.1080/2162402x.2015.1115941

Sampson, J. F., Hasegawa, E., Mulki, L., Suryawanshi, A., Jiang, S., Chen, W.-S., … Panjwani, N. (2015). Galectin-8 Ameliorates Murine Autoimmune Ocular Pathology and Promotes a Regulatory T Cell Response. PLOS ONE, 10(6), e0130772. https://doi.org/10.1371/journal.pone.0130772

Suryawanshi, A., & Manicassamy, S. (2015). Tumors induce immune tolerance through activation of β-catenin/TCF4 signaling in dendritic cells: A novel therapeutic target for cancer immunotherapy. OncoImmunology, 4(12), e1052932. https://doi.org/10.1080/2162402x.2015.1052932

Hong, Y., Manoharan, I., Suryawanshi, A., Majumdar, T., Angus-Hill, M. L., Koni, P. A., … Manicassamy, S. (2015). β-Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells. Cancer Research, 75(4), 656–665. https://doi.org/10.1158/0008-5472.can-14-2377

Reddy, P. B. J., Sehrawat, S., Suryawanshi, A., Rajasagi, N. K., Khatri, M., & Rouse, B. T. (2014). An Approach to Control Relapse of Inflammatory Lesions after Discontinuation of Primary Therapy. PLoS ONE, 9(5), e98051. https://doi.org/10.1371/journal.pone.0098051

Suryawanshi, A., Cao, Z., Sampson, J. F., & Panjwani, N. (2014). IL-17A–Mediated Protection againstAcanthamoebaKeratitis. The Journal of Immunology, 194(2), 650–663. https://doi.org/10.4049/jimmunol.1302707

Manoharan, I., Hong, Y., Suryawanshi, A., Angus-Hill, M. L., Sun, Z., Mellor, A. L., … Manicassamy, S. (2014). TLR2-Dependent Activation of β-Catenin Pathway in Dendritic Cells Induces Regulatory Responses and Attenuates Autoimmune Inflammation. The Journal of Immunology, 193(8), 4203–4213. https://doi.org/10.4049/jimmunol.1400614

Suryawanshi, A., Cao, Z., Thitiprasert, T., Zaidi, T. S., & Panjwani, N. (2013). Galectin-1–Mediated Suppression of <i>Pseudomonas aeruginosa</i>–Induced Corneal Immunopathology. The Journal of Immunology, 190(12), 6397–6409. https://doi.org/10.4049/jimmunol.1203501

Giménez, F., Suryawanshi, A., & Rouse, B. T. (2013). Pathogenesis of herpes stromal keratitis – A focus on corneal neovascularization. Progress in Retinal and Eye Research, 33, 1–9. https://doi.org/10.1016/j.preteyeres.2012.07.002

Rajasagi, N. K., Suryawanshi, A., Sehrawat, S., Reddy, P. B. J., Mulik, S., Hirashima, M., & Rouse, B. T. (2012). Galectin-1 Reduces the Severity of Herpes Simplex Virus-Induced Ocular Immunopathological Lesions. The Journal of Immunology, 188(9), 4631–4643. https://doi.org/10.4049/jimmunol.1103063

Suryawanshi, A., Veiga-Parga, T., Reddy, P. B. J., Rajasagi, N. K., & Rouse, B. T. (2012). IL-17A Differentially Regulates Corneal Vascular Endothelial Growth Factor (VEGF)-A and Soluble VEGF Receptor 1 Expression and Promotes Corneal Angiogenesis after Herpes Simplex Virus Infection. The Journal of Immunology, 188(7), 3434–3446. https://doi.org/10.4049/jimmunol.1102602

Veiga-Parga, T., Suryawanshi, A., Mulik, S., Giménez, F., Sharma, S., Sparwasser, T., & Rouse, B. T. (2012). On the Role of Regulatory T Cells during Viral-Induced Inflammatory Lesions. The Journal of Immunology, 189(12), 5924–5933. https://doi.org/10.4049/jimmunol.1202322

J Reddy, P. B., Schreiber, T. H., Rajasagi, N. K., Suryawanshi, A., Mulik, S., Veiga-Parga, T., … Rouse, B. T. (2012). TNFRSF25 Agonistic Antibody and Galectin-9 Combination Therapy Controls Herpes Simplex Virus-Induced Immunoinflammatory Lesions. Journal of Virology, 86(19), 10606–10620. https://doi.org/10.1128/jvi.01391-12

Mulik, S., Sharma, S., Suryawanshi, A., Veiga-Parga, T., Reddy, P. B. J., Rajasagi, N. K., & Rouse, B. T. (2011). Activation of Endothelial Roundabout Receptor 4 Reduces the Severity of Virus-Induced Keratitis. The Journal of Immunology, 186(12), 7195–7204. https://doi.org/10.4049/jimmunol.1100014

Sharma, S., Mulik, S., Kumar, N., Suryawanshi, A., & Rouse, B. T. (2011). An Anti-Inflammatory Role of VEGFR2/Src Kinase Inhibitor in Herpes Simplex Virus 1-Induced Immunopathology. Journal of Virology, 85(12), 5995–6007. https://doi.org/10.1128/jvi.00034-11

Rajasagi, N. K., Reddy, P. B. J., Suryawanshi, A., Mulik, S., Gjorstrup, P., & Rouse, B. T. (2011). Controlling Herpes Simplex Virus-Induced Ocular Inflammatory Lesions with the Lipid-Derived Mediator Resolvin E1. The Journal of Immunology, 186(3), 1735–1746. https://doi.org/10.4049/jimmunol.1003456

Veiga-Parga, T., Suryawanshi, A., & Rouse, B. T. (2011). Controlling Viral Immuno-Inflammatory Lesions by Modulating Aryl Hydrocarbon Receptor Signaling. PLoS Pathogens, 7(12), e1002427. https://doi.org/10.1371/journal.ppat.1002427

Reddy, P. B. J., Sehrawat, S., Suryawanshi, A., Rajasagi, N. K., Mulik, S., Hirashima, M., & Rouse, B. T. (2011). Influence of Galectin-9/Tim-3 Interaction on Herpes Simplex Virus-1 Latency. The Journal of Immunology, 187(11), 5745–5755. https://doi.org/10.4049/jimmunol.1102105

Suryawanshi, A., Mulik, S., Sharma, S., Reddy, P. B. J., Sehrawat, S., & Rouse, B. T. (2011). Ocular Neovascularization Caused by Herpes Simplex Virus Type 1 Infection Results from Breakdown of Binding between Vascular Endothelial Growth Factor A and Its Soluble Receptor. The Journal of Immunology, 186(6), 3653–3665. https://doi.org/10.4049/jimmunol.1003239

Suryawanshi, A., Veiga-Parga, T., Rajasagi, N. K., Reddy, P. B. J., Sehrawat, S., Sharma, S., & Rouse, B. T. (2011). Role of IL-17 and Th17 Cells in Herpes Simplex Virus-Induced Corneal Immunopathology. The Journal of Immunology, 187(4), 1919–1930. https://doi.org/10.4049/jimmunol.1100736

Sharma, S., Sundararajan, A., Suryawanshi, A., Kumar, N., Veiga-Parga, T., Kuchroo, V. K., … Rouse, B. T. (2011). T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses. Proceedings of the National Academy of Sciences, 108(47), 19001–19006. https://doi.org/10.1073/pnas.1107087108

Sehrawat, S., Reddy, P. B. J., Rajasagi, N., Suryawanshi, A., Hirashima, M., & Rouse, B. T. (2010). Galectin-9/TIM-3 Interaction Regulates Virus-Specific Primary and Memory CD8+ T Cell Response. PLoS Pathogens, 6(5), e1000882. https://doi.org/10.1371/journal.ppat.1000882

Naresha, S., Suryawanshi, A., Agarwal, M., Singh, B. P., & Joshi, P. (2009). Mapping the complement C1q binding site in Haemonchus contortus calreticulin. Molecular and Biochemical Parasitology, 166(1), 42–46. https://doi.org/10.1016/j.molbiopara.2009.02.007

Sehrawat, S., Suryawanshi, A., Hirashima, M., & Rouse, B. T. (2009). Role of Tim-3/Galectin-9 Inhibitory Interaction in Viral-Induced Immunopathology: Shifting the Balance toward Regulators. The Journal of Immunology, 182(5), 3191–3201. https://doi.org/10.4049/jimmunol.0803673

Sehrawat, S., Suvas, S., Sarangi, P. P., Suryawanshi, A., & Rouse, B. T. (2008). In Vitro-Generated Antigen-Specific CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup>Regulatory T Cells Control the Severity of Herpes Simplex Virus-Induced Ocular Immunoinflammatory Lesions. Journal of Virology, 82(14), 6838–6851. https://doi.org/10.1128/jvi.00697-08