Robert J Harrell

Works (17)

Updated: April 5th, 2024 01:07

2014 journal article

Lysine requirement of 1.5-5.5 kg pigs fed liquid diets

ANIMAL PRODUCTION SCIENCE, 54(5), 608–615.

By: J. Eisemann n, H. Lewis n, A. Broome n, K. Sullivan n, R. Boyd, J. Odle n , R. Harrell n

Contributors: J. Eisemann n, H. Lewis n, A. Broome n, K. Sullivan n, R. Boyd, J. Odle n , R. Harrell n

author keywords: neonatal pigs
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Acute effects of rotavirus and malnutrition on intestinal barrier function in neonatal piglets

World Journal of Gastroenterology, 19(31), 5094–5102.

By: S. Jacobi n, A. Moeser n, A. Blikslager n , J. Rhoads *, B. Corl *, R. Harrell n, J. Odle n 

Contributors: S. Jacobi n, A. Moeser n, A. Blikslager n , J. Rhoads *, B. Corl *, R. Harrell n, J. Odle n 

author keywords: Rotavirus gastroenteritis; Kwashiorkor; Occludin; Ussing chamber; Villus
MeSH headings : Animals; Animals, Newborn; Diarrhea / metabolism; Diarrhea / virology; Disease Models, Animal; Electric Impedance; Humans; Infant Formula / metabolism; Infant, Newborn; Intestinal Absorption; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Intestinal Mucosa / virology; Mannitol / metabolism; Occludin / metabolism; Permeability; Protein-Energy Malnutrition / metabolism; Protein-Energy Malnutrition / pathology; Protein-Energy Malnutrition / virology; Rotavirus Infections / metabolism; Rotavirus Infections / pathology; Rotavirus Infections / virology; Swine; Tight Junctions / metabolism; Tight Junctions / virology; Time Factors; Weight Loss
TL;DR: Overall, malnutrition had no additive effects to rotavirus infection on intestinal barrier function at day 3 post-infection in a neonatal piglet model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Dietary Long-Chain PUFA Enhance Acute Repair of Ischemia-Injured Intestine of Suckling Pigs

The Journal of Nutrition, 142(7), 1266–1271.

By: S. Jacobi n, A. Moeser n, B. Corl n, R. Harrell n, A. Blikslager n  & J. Odle n 

Contributors: S. Jacobi n, A. Moeser n, B. Corl n, R. Harrell n, A. Blikslager n  & J. Odle n 

MeSH headings : Animals; Constriction; Diet; Dietary Fats / pharmacology; Dietary Supplements; Eicosapentaenoic Acid / pharmacology; Electric Impedance; Ileal Diseases / drug therapy; Ileal Diseases / pathology; Ileal Diseases / physiopathology; Ileum / drug effects; Ileum / pathology; Ileum / physiopathology; Intestinal Mucosa / drug effects; Intestinal Mucosa / pathology; Intestinal Mucosa / physiopathology; Inulin / blood; Ischemia / drug therapy; Ischemia / pathology; Ischemia / physiopathology; Mannitol / blood; Mesentery / blood supply; Swine; Wound Healing / drug effects
TL;DR: It is demonstrated that feeding elevated levels of long-chain PUFA enhances acute recovery of ischemia-injured porcine ileum, and a histological evaluation of ischemic ilea from piglets fed the 5% ARA showed reduced histological lesions after ischemIA compared with the other dietary groups. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2011 journal article

Dietary Arachidonate Differentially Alters Desaturase-Elongase Pathway Flux and Gene Expression in Liver and Intestine of Suckling Pigs

The Journal of Nutrition, 141(4), 548–553.

By: S. Jacobi n, X. Lin n, B. Corl n, H. Hess n, R. Harrell n & J. Odle n 

Contributors: S. Jacobi n, X. Lin n, B. Corl n, H. Hess n, R. Harrell n & J. Odle n 

MeSH headings : Acetyltransferases / genetics; Acetyltransferases / metabolism; Animals; Animals, Suckling; Arachidonic Acid / administration & dosage; Delta-5 Fatty Acid Desaturase; Fatty Acid Desaturases / genetics; Fatty Acid Desaturases / metabolism; Fatty Acid Elongases; Fatty Acids / metabolism; Intestinal Mucosa / metabolism; Linoleoyl-CoA Desaturase / genetics; Linoleoyl-CoA Desaturase / metabolism; Liver / metabolism; Organ Specificity; Protein Transport; RNA, Messenger / analysis; Swine
TL;DR: D dietary ARA regulated the desaturase-elongase pathway in a tissue-specific manner in liver and intestine, and had modest effects on (n-6) fatty acid flux, and intestinal FADS2 activity and mRNA increased. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs

The Journal of Nutritional Biochemistry, 22(11), 1047–1054.

By: X. Lin n, J. Bo n, S. Oliver n, B. Corl n, S. Jacobi n, W. Oliver n, R. Harrell n, J. Odle n 

Contributors: X. Lin n, J. Bo n, S. Oliver n, B. Corl n, S. Jacobi n, W. Oliver n, R. Harrell n, J. Odle n 

MeSH headings : Acetyltransferases / metabolism; Animals; Animals, Newborn; Arachidonic Acid / metabolism; Brain / metabolism; Dietary Fats / administration & dosage; Fatty Acid Desaturases / metabolism; Fatty Acid Elongases; Fatty Acids, Unsaturated / metabolism; Linoleic Acid / metabolism; Linoleic Acids, Conjugated / pharmacology; Liver / metabolism; Swine
TL;DR: Overall, the data show that dietary CLA shifted the distribution of the synthetic products of [U-(13)C]LA between elongation and desaturation in liver and decreased the total synthetic products in brain by inhibiting LA elongation to C20:2n-6. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Enrichment of Intestinal Mucosal Phospholipids with Arachidonic and Eicosapentaenoic Acids Fed to Suckling Piglets Is Dose and Time Dependent

The Journal of Nutrition, 138(11), 2164–2171.

By: H. Hess n, B. Corl n, X. Lin n, S. Jacobi n, R. Harrell n, A. Blikslager n , J. Odle n 

Contributors: H. Hess n, B. Corl n, X. Lin n, S. Jacobi n, R. Harrell n, A. Blikslager n , J. Odle n 

MeSH headings : Animals; Arachidonic Acid / administration & dosage; Arachidonic Acid / pharmacology; Diet; Dose-Response Relationship, Drug; Drug Administration Schedule; Eicosapentaenoic Acid / administration & dosage; Eicosapentaenoic Acid / pharmacology; Intestinal Mucosa / drug effects; Intestinal Mucosa / metabolism; Lactase / metabolism; Swine
TL;DR: D doses demonstrate a dose-dependent response of intestinal mucosal phospholipid ARA concentration to dietary ARA with nearly full enrichment attained within 8 d of feeding formula containing ARA and that supra-physiologic supplementation of ARA is not detrimental to growth. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2007 journal article

Effect of animal plasma proteins on intestinal damage and recovery of neonatal pigs infected with rotavirus

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 18(12), 778–784.

By: B. Corl n, R. Harrell n, H. Moon n, O. Phillips n, E. Weaver*, J. Campbell *, J. Arthington *, J. Odle n 

Contributors: B. Corl n, R. Harrell n, H. Moon n, O. Phillips n, E. Weaver*, J. Campbell *, J. Arthington *, J. Odle n 

author keywords: rotavirus; piglet; plasma proteins; intestinal health
MeSH headings : Analysis of Variance; Animal Feed; Animals; Animals, Newborn; Blood Proteins / therapeutic use; Colostrum / physiology; Diarrhea / prevention & control; Diarrhea / virology; Dietary Proteins / therapeutic use; Disease Models, Animal; Rotavirus Infections / physiopathology; Rotavirus Infections / prevention & control; Soybean Proteins / therapeutic use; Swine
TL;DR: Findings from this study indicate the potential for using plasma proteins to improve the health of diarrheic neonates by reducing acute rotavirus intestinal damage or improved recovery. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Intestinal ribosomal p70(S6K) signaling is increased in piglet rotavirus enteritis

American Journal of Physiology-Gastrointestinal and Liver Physiology, 292(3), G913–G922.

By: J. Rhoads *, B. Corl  n, R. Harrell n, X. Niu*, L. Gatlin n, O. Phillips n, A. Blikslager n , A. Moeser n ...

Contributors: J. Rhoads *, B. Corl  n, R. Harrell n, X. Niu*, L. Gatlin n, O. Phillips n, A. Blikslager n , A. Moeser n, G. Wu *, J. Odle n 

author keywords: mammalian target of rapamycin; diarrhea; virus; malnutrition
MeSH headings : Amino Acids / blood; Animals; Animals, Newborn; Antigens, Viral / analysis; Body Weight; Diarrhea / metabolism; Diarrhea / pathology; Energy Intake; Enteritis / blood; Enteritis / metabolism; Enteritis / virology; Enterocytes / chemistry; Enterocytes / metabolism; Feces / chemistry; Intestinal Mucosa / chemistry; Intestinal Mucosa / metabolism; Jejunum / chemistry; Jejunum / metabolism; Lactase / metabolism; Malnutrition / metabolism; Malnutrition / physiopathology; Muscle, Skeletal / metabolism; Muscle, Smooth / metabolism; Phosphorylation; Protein Kinases / physiology; Ribosomal Protein S6 Kinases, 70-kDa / analysis; Ribosomal Protein S6 Kinases, 70-kDa / metabolism; Rotavirus Infections / blood; Rotavirus Infections / metabolism; Signal Transduction / physiology; Sus scrofa; TOR Serine-Threonine Kinases
TL;DR: In conclusion, intestinal activation of p70(S6K) was not inhibited by malnutrition but was strongly activated during an active state of mucosal regeneration, mainly in the crypt. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2005 journal article

Pigs weaned from the sow at 10 days of age respond to dietary energy source of manufactured liquid diets and exogenous porcine somatotropin

Journal of Animal Science, 83(5), 1002–1009.

By: W. Oliver n, K. Touchette, J. Coalson, C. Whisnant n, J. Brown n, S. Oliver n, J. Odle n , R. Harrell n

MeSH headings : Animal Feed / analysis; Animals; Blood Urea Nitrogen; Diet / veterinary; Dietary Fats / administration & dosage; Dietary Fats / pharmacology; Female; Growth Hormone / administration & dosage; Growth Hormone / pharmacology; Insulin-Like Growth Factor I / analysis; Insulin-Like Growth Factor I / drug effects; Leptin / blood; Male; Random Allocation; Swine / blood; Swine / growth & development; Time Factors; Weaning; Weight Gain / drug effects; Weight Gain / physiology
TL;DR: The results suggest that the ST/IGF axis is responsive in the young pig and the increase in circulating IGF-I and growth is independent of the source of dietary energy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2005 article

Vegetable proteins enhance the growth of milk-fed piglets, despite lower apparent lleal digestibility

Ebert, A. R., Berman, A. S., Harrell, R. J., Kessler, A. M., Cornelius, S. G., & Odle, J. (2005, September). JOURNAL OF NUTRITION, Vol. 135, pp. 2137–2143.

By: A. Ebert n, A. Berman n, R. Harrell n, A. Kessler  n, S. Cornelius n & J. Odle n 

author keywords: soy protein; amino acid digestibility; milk replacer
MeSH headings : Amino Acids / metabolism; Animals; Animals, Suckling / growth & development; Blood Urea Nitrogen; Body Composition; Diet; Digestion; Gastric Mucosa / metabolism; Hydrogen-Ion Concentration; Ileum / metabolism; Intestine, Small / anatomy & histology; Leucyl Aminopeptidase / metabolism; Milk; Plant Proteins, Dietary / metabolism; Plant Proteins, Dietary / pharmacology; Swine / anatomy & histology; Swine / growth & development; Tissue Distribution
TL;DR: Data support the conclusion that some processed vegetable proteins may be good alternatives to whey protein in liquid diets formulated for neonatal pigs and that an appropriate balance of amino acids is more important than the source of protein per se. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

A gonadotropin-releasing factor vaccine (Improvac) and porcine somatotropin have synergistic and additive effects on growth performance in group-housed boars and gilts

Journal of Animal Science, 81(8), 1959–1966.

By: W. Oliver n, L. McCauley*, R. Harrell n, D. Sustert, D. Kerton* & F. Dunshea*

MeSH headings : Absorptiometry, Photon / veterinary; Adipose Tissue / growth & development; Animals; Body Composition / drug effects; Body Composition / physiology; Drug Synergism; Female; Gonadotropin-Releasing Hormone / immunology; Growth Hormone / administration & dosage; Immunization / veterinary; Male; Random Allocation; Sexual Maturation; Swine / growth & development; Vaccines / administration & dosage; Weight Gain / drug effects
TL;DR: For pigs treated with both pST and Improvac, daily gain and lean tissue deposition rate was greater than for pigs that received either treatment alone, whereas fat deposition rate and feed intake did not differ from untreated control pigs. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

A GnRF vaccine (Improvac (R)) and porcine somatotropin (Reporcin (R)) have synergistic effects upon growth performance in both boars and gilts

AUSTRALIAN JOURNAL OF AGRICULTURAL RESEARCH, 54(1), 11–20.

By: I. McCauley, M. Watt, D. Suster, D. Kerton, W. Oliver*, R. Harrell*, F. Dunshea

author keywords: GnRF; feed intake; boar taint; testes; ovaries
TL;DR: The concomitant vaccination against GnRF and treatment with pST affords an opportunity to increase growth rate and feed intake above control levels and above those of pigs treated with either treatment alone. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 article

Comparison of triglycerides and phospholipids as supplemental sources of dietary long-chain polyunsaturated fatty acids in piglets

Mathews, S. A., Oliver, W. T., Phillips, O. T., Odle, J., Diersen-Schade, D. A., & Harrell, R. J. (2002, October). JOURNAL OF NUTRITION, Vol. 132, pp. 3081–3089.

By: S. Mathews n, W. Oliver n, O. Phillips n, J. Odle n , D. Diersen-Schade* & R. Harrell n

author keywords: long-chain polyunsaturated fatty acid; pigs; neonates; arachidonic acid; docosahexaenoic acid
MeSH headings : Alanine Transaminase / metabolism; Animal Feed; Animals; Animals, Newborn; Arachidonic Acid / blood; Aspartate Aminotransferases / metabolism; Dietary Fats, Unsaturated / administration & dosage; Digestion; Docosahexaenoic Acids / blood; Fatty Acids, Unsaturated / administration & dosage; Fatty Acids, Unsaturated / metabolism; Humans; Ileum / pathology; Infant Food / analysis; Infant Food / standards; Infant, Newborn; Phospholipids / administration & dosage; Phospholipids / metabolism; Random Allocation; Swine; Triglycerides / administration & dosage; Triglycerides / metabolism; Visual Acuity / drug effects; Visual Acuity / physiology
TL;DR: It is demonstrated that the algal/fungal TG sources of DHA and AA may be a more appropriate supplement for infant formulas than the egg PL source based on piglet plasma fatty acid profiles and apparent dry matter digestibilities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Effect of short-term feed restriction and refeeding on serum concentrations of leptin, luteinizing hormone and insulin in ovariectomized gilts

DOMESTIC ANIMAL ENDOCRINOLOGY, 22(2), 73–80.

By: C. Whisnant n & R. Harrell n

MeSH headings : Animals; Female; Food; Food Deprivation; Insulin / blood; Leptin / blood; Luteinizing Hormone / blood; Ovariectomy; Periodicity; Swine / blood
TL;DR: Reversal of treatment reversed the patterns of hormone secretion and confirmed previous observations that feed restriction can inhibit pulsatile LH secretion and also decrease leptin and insulin secretion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Efficacy of partially hydrolyzed corn syrup solids as a replacement for lactose in manufactured liquid diets for neonatal pigs

Journal of Animal Science, 80(1), 143–153.

By: W. Oliver n, S. Mathews n, O. Phillips n, E. Jones n, J. Odle n  & R. Harrell n

MeSH headings : Animal Feed; Animals; Animals, Newborn / metabolism; Blood Urea Nitrogen; Diet / veterinary; Dietary Carbohydrates / administration & dosage; Digestion; Food, Formulated / standards; Hydrolysis; Jejunum / anatomy & histology; Lactase; Lactose / administration & dosage; Nutritive Value; Random Allocation; Swine / metabolism; Treatment Outcome; Weaning; Weight Gain; Zea mays; alpha-Glucosidases / metabolism; beta-Galactosidase / metabolism
TL;DR: The results suggest that partially hydrolyzed CSS can be used as a replacement for lactose in manufactured liquid diets for neonatal pigs. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Liquid diets accelerate the growth of early-weaned pigs and the effects are maintained to market weight

Journal of Animal Science, 79(2), 427–434.

By: J. Kim n, K. Heo n, J. Odle  n, I. Han * & R. Harrell n

MeSH headings : Adipose Tissue / growth & development; Animal Feed; Animals; Hot Temperature; Housing, Animal; Linear Models; Milk / metabolism; Muscle Development; Muscle, Skeletal / growth & development; Random Allocation; Swine / growth & development; Swine / metabolism
TL;DR: It is shown that liquid feeding during early life can markedly accelerate piglet growth performance and that the growth advantage is maintained to market weight, with no evidence of compensatory gain in the dry-fed control pigs. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Nutritional approaches for improving neonatal piglet performance: Is there a place for liquid diets in commercial production? Review

ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 11(6), 774–780.

By: J. Odle*  & R. Harrell*

author keywords: neonatal pig; liquid diets; milk replacer; early weaning
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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