Barbara C. Hegarty Neupane, P., Hegarty, B. C., Marr, H. S., Maggi, R. G., Birkenheuer, A. J., & Breitschwerdt, E. B. (2018). Evaluation of cell culture-grown Bartonella antigens in immunofluorescent antibody assays for the serological diagnosis of bartonellosis in dogs. Journal of Veterinary Internal Medicine, 32(6), 1958–1964. https://doi.org/10.1111/jvim.15301 O’Nion, V. L., Montilla, H. J., Qurollo, B. A., Maggi, R. G., Hegarty, B. C., Tornquist, S. J., & Breitschwerdt, E. B. (2015). Potentially Novel Ehrlichia Species in Horses, Nicaragua. Emerging Infectious Diseases, 21(2), 335–338. https://doi.org/10.3201/eid2102.140290 Hegarty, B. C., Qurollo, B. A., Thomas, B., Park, K., Chandrashekar, R., Beall, M. J., … Breitschwerdt, E. B. (2015). Serological and molecular analysis of feline vector-borne anaplasmosis and ehrlichiosis using species-specific peptides and PCR. Parasites & Vectors, 8(1), 320. https://doi.org/10.1186/s13071-015-0929-8 Arraga-Alvarado, C. M., Qurollo, B. A., Parra, O. C., Berrueta, M. A., Hegarty, B. C., & Breitschwerdt, E. B. (2014). Case Report: Molecular Evidence of Anaplasma platys Infection in Two Women from Venezuela. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 91(6), 1161–1165. https://doi.org/10.4269/ajtmh.14-0372 Lanza-Perea, M., Zieger, U., Qurollo, B. A., Hegarty, B. C., Pultorak, E. L., Kumthekar, S., … Breitschwerdt, E. B. (2014). Intraoperative Bleeding in Dogs from Grenada Seroreactive to Anaplasma platys and Ehrlichia canis. Journal of Veterinary Internal Medicine, 28(6), 1702–1707. https://doi.org/10.1111/jvim.12442 Breitschwerdt, E. B., Hegarty, B. C., Qurollo, B. A., Saito, T. B., Maggi, R. G., Blanton, L. S., & Bouyer, D. H. (2014). Intravascular persistence of Anaplasma platys, Ehrlichia chaffeensis, and Ehrlichia ewingii DNA in the blood of a dog and two family members. Parasites & Vectors, 7(1), 298. https://doi.org/10.1186/1756-3305-7-298 Yancey, C. B., Hegarty, B. C., Qurollo, B. A., Levy, M. G., Birkenheuer, A. J., Weber, D. J., … Breitschwerdt, E. B. (2014). Regional Seroreactivity and Vector-Borne Disease Co-Exposures in Dogs in the United States from 2004–2010: Utility of Canine Surveillance. Vector-Borne and Zoonotic Diseases, 14(10), 724–732. https://doi.org/10.1089/vbz.2014.1592 Mascarelli, P. E., Maggi, R. G., Hopkins, S., Mozayeni, B. R., Trull, C. L., Bradley, J. M., … Breitschwerdt, E. B. (2013). Bartonella henselae infection in a family experiencing neurological and neurocognitive abnormalities after woodlouse hunter spider bites. Parasites & Vectors, 6(1), 98. https://doi.org/10.1186/1756-3305-6-98 Balakrishnan, N., Cherry, N. A., Linder, K. E., Pierce, E., Sontakke, N., Hegarty, B. C., … Breitschwerdt, E. B. (2013). Experimental infection of dogs with Bartonella henselae and Bartonella vinsonii subsp. berkhoffii. Veterinary Immunology and Immunopathology, 156(1-2), 153–158. https://doi.org/10.1016/j.vetimm.2013.09.007 Hegarty, B. C., Maggi, R. G., Koskinen, P., Beall, M. J., Eberts, M., Chandrashekar, R., & Breitschwerdt, E. B. (2012). Ehrlichia muris Infection in a Dog from Minnesota. Journal of Veterinary Internal Medicine, 26(5), 1217–1220. https://doi.org/10.1111/j.1939-1676.2012.00968.x Cherry, N. A., Maggi, R. G., Rossmeisl, J. H., Hegarty, B. C., & Breitschwerdt, E. B. (2011). Ecological Diversity ofBartonellaSpecies Infection Among Dogs and Their Owner in Virginia. Vector-Borne and Zoonotic Diseases, 11(11), 1425–1432. https://doi.org/10.1089/vbz.2010.0201 Breitschwerdt, E. B., Mascarelli, P. E., Schweickert, L. A., Maggi, R. G., Hegarty, B. C., Bradley, J. M., & Woods, C. W. (2011). Hallucinations, Sensory Neuropathy, and Peripheral Visual Deficits in a Young Woman Infected with Bartonella koehlerae. Journal of Clinical Microbiology, 49(9), 3415–3417. https://doi.org/10.1128/jcm.00833-11 Breitschwerdt, E. B., Hegarty, B. C., Maggi, R. G., Lantos, P. M., Aslett, D. M., & Bradley, J. M. (2011). Rickettsia rickettsii transmission by a lone star tick, North Carolina. Emerging Infectious Diseases, 17(5), 873–875. Breitschwerdt, E. B., Maggi, R. G., Lantos, P. M., Woods, C. W., Hegarty, B. C., & Bradley, J. M. (2010). Bartonella vinsonii subsp berkhoffii and Bartonella henselae bacteremia in a father and daughter with neurological disease. Parasites & Vectors, 3. Diniz, P. P. V. P., Beall, M. J., Omark, K., Chandrashekar, R., Daniluk, D. A., Cyr, K. E., … Breitschwerdt, E. B. (2010). High Prevalence of Tick-Borne Pathogens in Dogs from an Indian Reservation in Northeastern Arizona. Vector-Borne and Zoonotic Diseases, 10(2), 117–123. https://doi.org/10.1089/vbz.2008.0184 Breitschwerdt, E. B., Maggi, R. G., Mozayeni, B. R., Hegarty, B. C., Bradley, J. M., & Mascarelli, P. E. (2010). PCR amplification of Bartonella koehlerae from human blood and enrichment blood cultures. Parasites & Vectors, 3. Hegarty, B. C., Diniz, P. P. V. de P., Bradley, J. M., Lorentzen, L., & Breitschwerdt, E. (2009). Clinical Relevance of Annual Screening Using a Commercial Enzyme-Linked Immunosorbent Assay (SNAP 3Dx) for Canine Ehrlichiosis. JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, Vol. 45, pp. 118–124. https://doi.org/10.5326/0450118 Lappin, M. R., Breitschwerdt, E., Brewer, M., Hawley, J., Hegarty, B., & Radecki, S. (2009). Prevalence of Bartonella species antibodies and Bartonella species DNA in the blood of cats with and without fever. Journal of Feline Medicine and Surgery, 11(2), 141–148. https://doi.org/10.1016/j.jfms.2008.06.005 Kidd, L., Maggi, R., Diniz, P. P. V. P., Hegarty, B., Tucker, M., & Breitschwerdt, E. (2008). Evaluation of conventional and real-time PCR assays for detection and differentiation of Spotted Fever Group Rickettsia in dog blood. Veterinary Microbiology, 129(3-4), 294–303. https://doi.org/10.1016/j.vetmic.2007.11.035 Cadenas, M. B., Bradley, J., Maggi, R., Takara, M., Hegarty, B. C., & Breitschwerdt, E. (2008). Molecular characterization of Bartonella vinsonii subsp berkhoffii genotype III. Journal of Clinical Microbiology, 46(5), 1858–1860. https://doi.org/10.1128/JCM.62456-07 Beall, M. J., Chandrashekar, R., Eberts, M. D., Cyr, K. E., Diniz, P. P. V. P., Mainville, C., … Breitschwerdt, E. B. (2008). Serological and Molecular Prevalence of Borrelia burgdorferi, Anaplasma phagocytophilum, and Ehrlichia Species in Dogs from Minnesota. Vector-Borne and Zoonotic Diseases, 8(4), 455–464. https://doi.org/10.1089/vbz.2007.0236 Breitschwerdt, E. B., Maggi, R. G., Duncan, A. W., Nicholson, W. L., Hegarty, B. C., & Woods, C. W. (2007). BartonellaSpecies in Blood of Immunocompetent Persons with Animal and Arthropod Contact. Emerging Infectious Diseases, 13(6), 938–941. https://doi.org/10.3201/eid1306.061337 Vissotto De Paiva Diniz, P. P., Maggi, R. G., Schwartz, D. S., Cadenas, M. B., Bradley, J. M., Hegarty, B., & Breitschwerdt, E. B. (2007). Canine bartonellosis: serological and molecular prevalence in Brazil and evidence of co-infection with Bartonella henselae and Bartonella vinsonii subsp berkhoffii. VETERINARY RESEARCH, 38(5), 697–710. https://doi.org/10.1051/vetres:2007023 Eddlestone, S. M., Diniz, P. P. V. P., Neer, T. M., Gaunt, S. D., Corstvet, R., Cho, D., … Breitschwerdt, E. B. (2007). Doxycycline Clearance of Experimentally Induced Chronic Ehrlichia Canis Infection in Dogs. Journal of Veterinary Internal Medicine, 21(6), 1237–1242. https://doi.org/10.1892/07-061.1 Jones, S. L., Valenzisi, A., Sontakke, S., Sprayberry, K. A., Maggi, R., Hegarty, B., & Breitschwerdt, E. (2007). Use of an insect cell culture growth medium to isolate bacteria from horses with effusive, fibrinous pericarditis: A preliminary study. Veterinary Microbiology, 121(1-2), 177–181. https://doi.org/10.1016/j.vetmic.2006.11.024 Maggi, R. G., Chomel, B., Hegarty, B. C., Henn, J., & Breitschwerdt, E. B. (2006). A Bartonella vinsonii berkhoffii typing scheme based upon 16S–23S ITS and Pap31 sequences from dog, coyote, gray fox, and human isolates. Molecular and Cellular Probes, 20(2), 128–134. https://doi.org/10.1016/j.mcp.2005.11.002 Solano-Gallego, L., Llull, J., Osso, M., Hegarty, B., & Breitschwerdt, E. (2006). A serological study of exposure to arthropod-borne pathogens in dogs from northeastern Spain. VETERINARY RESEARCH, 37(2), 231–244. https://doi.org/10.1051/vetres:2005054 O'Connor, T. P., Hanscom, J. L., Hegarty, B. C., Groat, R. G., & Breitschwerdt, E. B. (2006). Comparison of an indirect immunofluorescence assay, western blot analysis, and a commercially available ELISA for detection ofEhrlichia canisantibodies in canine sera. American Journal of Veterinary Research, 67(2), 206–210. https://doi.org/10.2460/ajvr.67.2.206 Hess, P. R., English, R. V., Hegarty, B. C., Brown, G. D., & Breitschwerdt, E. B. (2006). Experimental Ehrlichia canis infection in the dog does not cause immunosuppression. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 109(1-2), 117–125. https://doi.org/10.1016/j.vetimm.2005.07.027 Eddlestone, S. M., Neer, T. M., Gaunt, S. D., Corstvet, R., Gill, A., Hosgood, G., … Breitschwerdt, E. B. (2006). Failure of imidocarb dipropionate to clear experimentally induced Ehrlichia canis infection in dogs. Journal of Veterinary Internal Medicine, 20(4), 840–844. Kidd, L., Hegarty, B., Sexton, D., & Breitschwerdt, E. (2006). Molecular characterization of Rickettsia rickettsii infecting dogs and people in North Carolina. In Century of rickettsiology: emerging, reemerging rickettsioses, molecular diagnostics, and emerging veterinary rickettsioses (Vol. 1078, pp. 400–409). Oxford: Blackwell Publishing. Solano-Gallego, L., Hegarty, B., Espada, Y., Llull, J., & Breitschwerdt, E. (2006). Serological and molecular evidence of exposure to arthropod-borne organisms in cats from northeastern Spain. VETERINARY MICROBIOLOGY, 118(3-4), 274–277. https://doi.org/10.1016/j.vetmic.2006.07.010 Gary, A. T., Webb, J. A., Hegarty, B. C., & Breitschwerdt, E. B. (2006). The low seroprevalence of tick-transmitted agents of disease in dogs from southern Ontario and Quebec. Canadian Veterinary Journal, 47(12), 1194–1200. Lester, S. J., Breitschwerdt, E. B., Collis, C. D., & Hegarty, B. C. (2005). Anaplasma phagocytophilum infection (granulocytic anaplasmosis) in a dog from Vancouver Island. Canadian Veterinary Journal, 46(9), 825–827. Breitschwerdt, E. B., Hegarty, B. C., Maggi, R., Hawkins, E., & Dyer, P. (2005). Bartonella Species as a Potential Cause of Epistaxis in Dogs. Journal of Clinical Microbiology, 43(5), 2529–2533. https://doi.org/10.1128/JCM.43.5.2529-2533.2005 O'Rourke, L. G., Pitulle, C., Hegarty, B. C., Kraycirik, S., Killary, K. A., Grosenstein, P., … Breitschwerdt, E. B. (2005). Bartonella quintana in Cynomolgus Monkey (Macaca fascicularis). Emerging Infectious Diseases, 11(12), 1931–1934. https://doi.org/10.3201/eid1112.030045 Solano-Gallego, L., Bradley, J., Hegarty, B., Sigmon, B., & Breitschwerdt, E. (2004). Bartonella henselae IgG antibodies are prevalent in dogs from southeastern USA. VETERINARY RESEARCH, 35(5), 585–595. https://doi.org/10.1051/vetres:2004034 Mylonakis, M. E., Koutinas, A. F., Breitschwerdt, E. B., Hegarty, B. C., Billinis, C. D., Leontides, L. S., & Kontos, V. S. (2004). Chronic canine ehrlichiosis (Ehrlichia canis): A retrospective study of 19 natural cases. JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 40(3), 174–184. https://doi.org/10.5326/0400174 Seaman, R. L., Kania, S. A., Hegarty, B. C., Legendre, A. M., & Breitschwerdt, E. B. (2004). Comparison of results for serologic testing and a polymerase chain reaction assay to determine the prevalence of stray dogs in eastern Tennessee seropositive to Ehrlichia canis. American Journal of Veterinary Research, 65(9), 1200–1203. https://doi.org/10.2460/ajvr.2004.65.1200 Ober, C. P., Spaulding, K., Breitschwerdt, E. B., Malarkey, D. E., & Hegarty, B. C. (2004). ORCHITIS IN TWO DOGS WITH ROCKY MOUNTAIN SPOTTED FEVER. Veterinary Radiology & Ultrasound, 45(5), 458–465. https://doi.org/10.1111/j.1740-8261.2004.04079.x Goodman, R. A., Hawkins, E. C., Olby, N. J., Grindem, C. B., Hegarty, B., & Breitschwerdt, E. B. (2003). Molecular identification of Ehrlichia ewingii infection in dogs: 15 cases (1997-2001). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 222(8), 1102–1107. https://doi.org/10.2460/javma.2003.222.1102 Breitschwerdt, E. B., Suksawat, J., Chomel, B., & Hegarty, B. C. (2003). The Immunologic Response of Dogs to Bartonella Vinsonii Subspecies Berkhoffii Antigens: as Assessed by Western Immunoblot Analysis. Journal of Veterinary Diagnostic Investigation, 15(4), 349–354. https://doi.org/10.1177/104063870301500408 Beaufils, J. P., Breitschwerdt, E., Hancock, S. I., Hegarty, B. C., Martin-Granel, J., Jumelle, P., … Blavier, A. (2002). Feline ehrlichiosis. The genetic identification of the agent in Avo cats. Pratique Medicale Et Chirurgicale De L'Animal De Compagnie, 37(3), 235–238. Breitschwerdt, E. B., Abrams-Ogg, A. C. G., Lappin, M. R., Bienzle, D., Hancock, S. I., Cowan, S. M., … Hawkins, E. C. (2002). Molecular evidence supporting Ehrlichia canis-like infection in cats. JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 16, pp. 642–649. https://doi.org/10.1892/0891-6640(2002)016<0642:MESCII>2.3.CO;2 Williams, C. V., Van Steenhouse, J. L., Bradley, J. M., Hancock, S. I., Hegarty, B. C., & Breitschwerdt, E. B. (2002). Naturally OccurringEhrlichia chaffeensisInfection in Two Prosimian Primate Species: Ring-tailed Lemurs (Lemur catta) and Ruffed Lemurs (Varecia variegata). Emerging Infectious Diseases, 8(12), 1497–1500. https://doi.org/10.3201/eid0812.020085 Gaskin, A. A., Schantz, P., Jackson, J., Birkenheuer, A., Tomlinson, L., Gramiccia, M., … Breitschwerdt, E. B. (2002). Visceral leishmaniasis in a New York foxhound kennel. JOURNAL OF VETERINARY INTERNAL MEDICINE, 16(1), 34–44. https://doi.org/10.1892/0891-6640(2002)016<0034:VLIANY>2.3.CO;2 Hinrichsen, V. L., Whitworth, U. G., Breitschwerdt, E. B., Hegarty, B. C., & Mather, T. N. (2001). Assessing the association between the geographic distribution of deer ticks and seropositivity rates to various tick-transmitted disease organisms in dogs. Journal of the American Veterinary Medical Association, 218(7), 1092–1097. https://doi.org/10.2460/javma.2001.218.1092 Munana, K. R., Vitek, S. M., Hegarty, B. C., Kordick, D. L., & Breitschwerdt, E. B. (2001). Infection of Fetal Feline Brain Cells in Culture with Bartonella henselae. Infection and Immunity, 69(1), 564–569. https://doi.org/10.1128/IAI.69.1.564-569.2001 Suksawat, J., Yu, X. J., Hancock, S. I., Hegarty, B. C., Nilkumhang, P., & Breitschwerdt, E. B. (2001). Serologic and molecular evidence of coinfection with multiple vector-borne pathogens in dogs from Thailand. JOURNAL OF VETERINARY INTERNAL MEDICINE, 15(5), 453–462. https://doi.org/10.1892/0891-6640(2001)015<0453:SAMEOC>2.3.CO;2 Suksawat, J., Hegarty, B. C., & Breitschwerdt, E. (2000). Seroprevalence of Ehrlichia canis, Ehrlichia equi, and Ehrlichia risticii in sick dogs from North Carolina and Virginia. Journal of Veterinary Internal Medicine, 14(1), 50–55. https://doi.org/10.1111/j.1939-1676.2000.tb01499.x Kordick, S. K., Breitschwerdt, E. B., Hegarty, B. C., Southwick, K. L., Colitz, C. M., Hancock, S. I., … MacCormack, J. N. (1999). Coinfection with multiple tick-borne pathogens in a Walker Hound kennel in North Carolina. Journal of Clinical Microbiology, 37(8), 2631–2638. Breitschwerdt, E. B., Papich, M. G., Hegarty, B. C., Gilger, B., Hancock, S. I., & Davidson, M. G. (1999). Efficacy of Doxycycline, Azithromycin, or Trovafloxacin for Treatment of Experimental Rocky Mountain Spotted Fever in Dogs. Antimicrobial Agents and Chemotherapy, 43(4), 813–821. https://doi.org/10.1128/aac.43.4.813 Grindem, C. B., Breitschwerdt, E. B., Perkins, P. C., Cullins, L. D., Thomas, T. J., & Hegarty, B. C. (1999). Platelet-associated immunoglobulin (antiplatelet antibody) in canine Rocky Mountain spotted fever and ehrlichiosis. JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 35(1), 56–61. https://doi.org/10.5326/15473317-35-1-56 Carpenter, C. F., Gandhi, T. K., Kong, L. K., Corey, G. R., Chen, S. M., Walker, D. H., … al. (1999, September). The incidence of ehrlichial and rickettsial infection in patients with unexplained fever and recent history of tick bite in central North Carolina. JOURNAL OF INFECTIOUS DISEASES, Vol. 180, pp. 900–903. https://doi.org/10.1086/314954 Baneth, G., Breitschwerdt, E. B., Hegarty, B. C., Pappalardo, B., & Ryan, J. (1998). A survey of tick-borne bacteria and protozoa in naturally exposed dogs from Israel. VETERINARY PARASITOLOGY, 74(2-4), 133–142. https://doi.org/10.1016/S0304-4017(97)00149-0 Breitschwerdt, E. B., Hegarty, B. C., & Hancock, S. I. (1998). Doxycycline hyclate treatment of experimental canine ehrlichiosis followed by challenge inoculation with two Ehrlichia canis strains. Antimicrobial Agents and Chemotherapy, 42(2), 362–368. Sexton, D., Corey, G. R., Carpenter, C., Kong, L. Q., Gandhi, T., Breitschwerdt, E. B., … Dumler, S. J. (1998). Dual Infection with Ehrlichia chaffeensis and a Spotted Fever Group Rickettsia: A Case Report. Emerging Infectious Diseases, 4(2), 311–316. https://doi.org/10.3201/eid0402.980222 Goldman, E. E., Breitschwerdt, E. B., Grindem, C. B., Hegarty, B. C., Walls, J. J., & Dumler, J. S. (1998). Granulocytic Ehrlichiosis in Dogs from North Carolina and Virginia. Journal of Veterinary Internal Medicine, 12(2), 61–70. https://doi.org/10.1111/j.1939-1676.1998.tb02096.x Breitschwerdt, E. B., Hegarty, B. C., & Hancock, S. I. (1998). Sequential evaluation of dogs naturally infected with Ehrlichia canis, Ehrlichia chaffeensis, Ehrlichia equi, Ehrlichia ewingii, or Bartonella vinsonii. Journal of Clinical Microbiology, 36(9), 2645–2651. Hegarty, B. C., Levy, M. G., Gager, R. F., & Breitschwerdt, E. B. (1997). Immunoblot Analysis of the Immunoglobulin G Response to Ehrlichia Canis in Dogs: An International Survey. Journal of Veterinary Diagnostic Investigation, 9(1), 32–38. https://doi.org/10.1177/104063879700900106 Breitschwerdt, E. B., Davidson, M. G., Hegarty, B. C., Papich, M. G., & Grindem, C. B. (1997). Prednisolone at anti-inflammatory or immunosuppressive dosages in conjunction with doxycycline does not potentiate the severity of Rickettsia rickettsii infection in dogs. Antimicrobial Agents and Chemotherapy, 41(1), 141–147. https://doi.org/10.1128/aac.41.1.141 Breitschwerdt, E. B., Geoly, F. J., Meuten, D. J., Levine, J. F., Howard, P., Hegarty, B. C., & Stafford, L. C. (1996). Myocarditis in mice and guinea pigs experimentally infected with a canine-origin Borrelia isolate from Florida. American Journal of Veterinary Research, 57(4), 505–511.