Bram Frohock

Works (4)

Updated: March 9th, 2024 05:01

2024 article

Expanded library of novel 2,3-pyrrolidinedione analogues exhibit anti-biofilm activity

Nie, M., Valdes-Pena, M. A., Frohock, B. H., Smits, E., Daiker, J. C., Gilbertie, J. M., … Pierce, J. G. (2024, February 1). BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol. 99.

By: M. Nie n, M. Valdes-Pena  n, B. Frohock n, E. Smits n, J. Daiker n, J. Gilbertie n, L. V. Schnabel  n, J. Pierce n 

author keywords: Natural products; Antibiotics; Antimicrobial resistance; Biofilms; 2 3-pyrrolidinedione
TL;DR: A new library of 2,3-pyrrolidinedione analogues is reported that expands on the previous report on the antimicrobial studies of this heterocyclic scaffold and displayed antibiofilm properties and represent intriguing scaffolds for further optimization and development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 7, 2024

2022 article

Engagement of Students in an Organic Chemistry Lecture/Lab Course via Social Media Using Twitter

Frohock, B. H., Macallister, C. A., & Gallardo-Williams, M. T. (2022, August 15). JOURNAL OF CHEMICAL EDUCATION, Vol. 8.

By: B. Frohock n, C. Macallister n & M. Gallardo-Williams n 

author keywords: Second-Year Undergraduate; Organic Chemistry; Internet; Web-Based Learning; Multimedia-Based Learning; Computer-Based Learning
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 29, 2022

2019 article

5-Benzylidene-4-Oxazolidinones Are Synergistic with Antibiotics for the Treatment of Staphylococcus aureus Biofilms

CHEMBIOCHEM, Vol. 12.

By: B. Frohock n, J. Gilbertie n, J. Daiker n, L. Schnabel n & J. Pierce n 

MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / pharmacology; Benzylidene Compounds / pharmacology; Biofilms / drug effects; Drug Synergism; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Oxazolidinones / pharmacology; Staphylococcus aureus / physiology; Structure-Activity Relationship
TL;DR: An expanded set of 5‐benzylidene‐4‐oxazolidinones is reported that is able to inhibit the formation of Staphylococcus aureus biofilms, disperse preformed biofilm, and are able to significantly reduce the bacterial load in a robust collagen‐matrix model of biofilm infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 13, 2020

2017 journal article

#IHeartChemistryNCSU: free choice, content, and elements of science communication as the framework for an introductory organic chemistry project

CHEMISTRY EDUCATION RESEARCH AND PRACTICE, 19(1), 240–250.

By: B. Frohock n, S. Winterrowd n & M. Gallardo-Williams n 

UN Sustainable Development Goal Categories
4. Quality Education (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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