Blanca Irene Escudero-Abarca

Works (12)

Updated: July 5th, 2023 15:45

2022 article

Comparative Assessment of the Efficacy of Commercial Hand Sanitizers Against Human Norovirus Evaluated by an in vivo Fingerpad Method

Escudero-Abarca, B. I., Goulter, R. M., Manuel, C. S., Leslie, R. A., Green, K., Arbogast, J. W., & Jaykus, L.-A. (2022, April 7). Frontiers in Microbiology.

By: B. Escudero-Abarca n, R. Goulter n, C. Manuel*, R. Leslie *, K. Green*, J. Arbogast *, L. Jaykus n

author keywords: human norovirus; hand sanitizer; hand hygiene; fingerpad method; alcohol
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Clostridium difficile and Clostridium perfringens research
TL;DR: There remains a need for more hand sanitizer formulations having greater activity against hNoV, a virus that is comparatively recalcitrant relative to other pathogens of concern in community, healthcare, and food preparation environments. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 16, 2022

2022 article

Efficacy of an alcohol-based surface disinfectant formulation against human norovirus

Escudero-Abarca, B. I., Goulter, R. M., Bradshaw, J., Faircloth, J., Leslie, R. A., Manuel, C. S., … Jaykus, L.-A. (2022, February 9). Journal of Applied Microbiology.

By: B. Escudero-Abarca n, R. Goulter n, J. Bradshaw n, J. Faircloth n, R. Leslie *, C. Manuel*, J. Arbogast *, L. Jaykus n

author keywords: food safety; food virology; human intestinal enteroids; human norovirus; surface disinfection; surface sanitizing; Tulane virus
MeSH headings : Disinfectants / pharmacology; Disinfection / methods; Ethanol; Humans; Norovirus / genetics; Sodium Hypochlorite / pharmacology; Soil; Stainless Steel
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Infection Control and Ventilation
TL;DR: To evaluate the anti‐noroviral efficacy of PURELL® surface sanitizer and disinfectant spray (PSS, an alcohol‐based formulation) using human norovirus GII.4 Sydney and its cultivable surrogate, Tulane virus (TuV, infectivity assay), compared to sodium hypochlorite (NaOCl) solutions. (via Semantic Scholar)
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Source: Web Of Science
Added: March 14, 2022

2022 article

The Efficacy of Commercial Surface Sanitizers against Norovirus on Formica Surfaces with and without Inclusion of a Wiping Step

Faircloth, J., Goulter, R. M., Manuel, C. S., Arbogast, J. W., Escudero-Abarca, B., & Jaykus, L.-A. (2022, August 25). Applied and Environmental Microbiology.

By: J. Faircloth n, R. Goulter n, C. Manuel *, J. Arbogast *, B. Escudero-Abarca n & L. Jaykus n

author keywords: human norovirus; Tulane virus; sanitize; disinfect; wiping
MeSH headings : Animals; Calicivirus, Feline; Cats; Disinfectants / pharmacology; Ethanol; Gastroenteritis; Humans; Norovirus / genetics; Quaternary Ammonium Compounds; Virus Inactivation; Water
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Infection Control and Ventilation
TL;DR: Assessment of the anti-hNoV efficacy of various surface sanitizer chemistries, as applied to a laminate material commonly used for restaurant tabletops, using standard surface assays and a newly developed wiping protocol highlights the importance of wiping in the process of sanitization. (via Semantic Scholar)
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Source: Web Of Science
Added: September 6, 2022

2020 article

Efficacy of alcohol‐based hand sanitizers against human norovirus using RNase‐RT‐qPCR with validation by human intestinal enteroid replication

Escudero‐Abarca, B. I., Goulter, R. M., Arbogast, J. W., Leslie, R. A., Green, K., & Jaykus, L. A. (2020, September 22). Letters in Applied Microbiology.

By: B. Escudero‐Abarca n, R. Goulter n, J. Arbogast *, R. Leslie*, K. Green * & L. Jaykus n

author keywords: disinfection; food safety; human intestinal enteroids; human norovirus; RT-qPCR
MeSH headings : Caliciviridae Infections / virology; Drug Evaluation, Preclinical; Ethanol / pharmacology; Hand Sanitizers / pharmacology; Humans; Intestines / virology; Norovirus / drug effects; Norovirus / genetics; Norovirus / growth & development; Norovirus / physiology; Real-Time Polymerase Chain Reaction / instrumentation; Ribonucleases / metabolism; Virus Replication / drug effects
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Animal Virus Infections Studies
TL;DR: The purpose of this study was to evaluate the anti‐HuNoV efficacy of two alcohol‐based commercial hand sanitizers and 60% ethanol by suspension assay using RNase‐RT‐qPCR, with subsequent validation of efficacy by HuNoV cultivation using the HIE model. (via Semantic Scholar)
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Source: Web Of Science
Added: October 19, 2020

2019 article

Comparison of estimated norovirus infection risk reductions for a single fomite contact scenario with residual and nonresidual hand sanitizers

Wilson, A. M., Reynolds, K. A., Jaykus, L.-A., Escudero-Abarca, B., & Gerba, C. P. (2019, October 29). American Journal of Infection Control.

By: A. Wilson *, K. Reynolds *, L. Jaykus n, B. Escudero-Abarca n & C. Gerba *

author keywords: Norovirus; Hand sanitizer; Risk reduction; Risk target
MeSH headings : Adult; Caliciviridae Infections / prevention & control; Caliciviridae Infections / virology; Ethanol / administration & dosage; Female; Fomites / virology; Hand / virology; Hand Disinfection / methods; Hand Sanitizers / administration & dosage; Hand Sanitizers / chemistry; Humans; Male; Norovirus / drug effects; Risk Reduction Behavior; Time Factors; Virus Inactivation / drug effects
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Infection Control and Ventilation; Infection Control in Healthcare
TL;DR: Residual antinoroviral hand sanitizers may reduce infection risks for up to 4 hours, and log10 virus and infection risk reductions were consistently greater for the residualHand sanitizer under all scenarios. (via Semantic Scholar)
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Source: Web Of Science
Added: June 15, 2020

2018 article

Use of DNA aptamer for sandwich type detection of Listeria monocytogenes

Suh, S. H., Choi, S. J., Dwivedi, H. P., Moore, M. D., Escudero-Abarca, B. I., & Jaykus, L.-A. (2018, April 9). Analytical Biochemistry.

By: S. Suh  n, S. Choi *, H. Dwivedi  n, M. Moore  n, B. Escudero-Abarca n & L. Jaykus n

MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / genetics; Enzyme-Linked Immunosorbent Assay; Listeria monocytogenes / cytology; Listeria monocytogenes / isolation & purification
topics (OpenAlex): Biosensors and Analytical Detection; Listeria monocytogenes in Food Safety; Identification and Quantification in Food
TL;DR: A single stranded (ss) DNA aptamer, specific to members of Listeria genus, was used to develop a two-site binding sandwich assay for capture and detection of L. monocytogenes. (via Semantic Scholar)
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Source: NC State University Libraries
Added: October 19, 2018

2017 article

Evaluation of a Surface Sampling Method for Recovery of Human Noroviruses Prior to Detection Using Reverse Transcription Quantitative PCR

Tung-Thompson, G., Escudero-Abarca, B. I., Outlaw, J., Ganee, A., Cassard, S., Mabilat, C., & Jaykus, L.-A. (2017, January 20). Journal of Food Protection.

By: G. Tung-Thompson n, B. Escudero-Abarca n, J. Outlaw n, A. Ganee*, S. Cassard*, C. Mabilat*, L. Jaykus n

author keywords: Norovirus; Sampling; Surfaces; Wipes
MeSH headings : Caliciviridae Infections / virology; Feces / virology; Gastroenteritis / epidemiology; Humans; Norovirus / genetics; North Carolina; RNA, Viral; Reverse Transcriptase Polymerase Chain Reaction; Reverse Transcription
topics (OpenAlex): Viral gastroenteritis research and epidemiology
TL;DR: Wipes evaluated for their efficacy at recovering human norovirus from hard surfaces and foods may be a valuable tool for investigations of Norovirus outbreaks and studies of norov virus prevalence. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2015 article

Generation and characterization of nucleic acid aptamers targeting the capsid P domain of a human norovirus GII.4 strain

Moore, M. D., Escudero-Abarca, B. I., Suh, S. H., & Jaykus, L.-A. (2015, June 14). Journal of Biotechnology.

By: M. Moore n, B. Escudero-Abarca n, S. Suh n & L. Jaykus n

author keywords: SELEX; Aptamer; Norovirus; Molecular detection; Viral diagnostics
MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Capsid Proteins / genetics; Capsid Proteins / metabolism; Feces / virology; Humans; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; SELEX Aptamer Technique / methods; Sensitivity and Specificity
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Virus-based gene therapy research
TL;DR: This is the first demonstration of human NoV P domain protein as a functional target for the selection of nucleic acid aptamers that specifically bind and broadly recognize diversehuman NoV strains. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 article

Molecular methods used to estimate thermal inactivation of a prototype human norovirus: More heat resistant than previously believed?

Escudero-Abarca, B. I., Rawsthorne, H., Goulter, R. M., Suh, S. H., & Jaykus, L. A. (2014, January 30). Food Microbiology.

By: B. Escudero-Abarca n, H. Rawsthorne n, R. Goulter*, S. Suh n & L. Jaykus n

author keywords: Human norovirus; Thermal inactivation; Heat resistance
MeSH headings : Azides / chemistry; Caliciviridae Infections / virology; Hot Temperature; Humans; Norovirus / chemistry; Norovirus / genetics; Norovirus / isolation & purification; Norovirus / physiology; Polymerase Chain Reaction; Propidium / analogs & derivatives; Propidium / chemistry; RNA, Viral / chemistry; RNA, Viral / genetics; Virus Inactivation
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Animal Virus Infections Studies
TL;DR: Electron microscopy data applied to heat-treated virus-like particles supported this relatively high degree of thermal resistance and suggest that SMV is more heat resistant than common cultivable HuNoV surrogates. (via Semantic Scholar)
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Added: August 6, 2018

2014 article

Selection, Characterization and Application of Nucleic Acid Aptamers for the Capture and Detection of Human Norovirus Strains

Escudero-Abarca, B. I., Suh, S. H., Moore, M. D., Dwivedi, H. P., & Jaykus, L.-A. (2014, September 5). PLoS ONE.

By: B. Escudero-Abarca n, S. Suh n, M. Moore n, H. Dwivedi n & L. Jaykus n

MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Bacteriological Techniques / methods; DNA, Viral / chemistry; DNA, Viral / metabolism; Feces / virology; Food Microbiology; Humans; Lettuce / virology; Molecular Structure; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; Sensitivity and Specificity
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Animal Virus Infections Studies; Viral Infections and Immunology Research
TL;DR: These ssDNA aptamer candidates show promise as broadly reactive reagents for use in HuNoV capture and detection assays in various sample types. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2013 article

Laboratory Evidence of Norwalk Virus Contamination on the Hands of Infected Individuals

Liu, P., Escudero, B., Jaykus, L.-A., Montes, J., Goulter, R. M., Lichtenstein, M., … Moe, C. L. (2013, October 12). Applied and Environmental Microbiology.

By: P. Liu *, B. Escudero n, L. Jaykus n, J. Montes*, R. Goulter n, M. Lichtenstein*, M. Fernandez *, J. Lee* ...

MeSH headings : Caliciviridae Infections / virology; Gastroenteritis / virology; Hand / virology; Humans; Norwalk virus / isolation & purification; RNA, Viral / genetics; RNA, Viral / isolation & purification; Real-Time Polymerase Chain Reaction; Viral Load
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Infection Control and Ventilation; Virus-based gene therapy research
TL;DR: Findings provide definitive evidence of NV contamination on the hands of infected subjects observed under controlled clinical research conditions, and support the need for better hand hygiene strategies to prevent NoV transmission. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2012 article

Persistence and Transferability of Noroviruses on and between Common Surfaces and Foods

Escudero, B. I., Rawsthorne, H., Gensel, C., & Jaykus, L. A. (2012, May 1). Journal of Food Protection.

By: B. Escudero n, H. Rawsthorne n, C. Gensel n & L. Jaykus n

MeSH headings : Colony Count, Microbial; Consumer Product Safety; Equipment Contamination; Food Contamination / analysis; Food Handling / methods; Food Microbiology; Humans; Hygiene; Norovirus / growth & development; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Time Factors; Viral Plaque Assay
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Infection Control and Ventilation
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Source: Web Of Science
Added: August 6, 2018

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