Bartosz Kempisty

Works (50)

Updated: July 2nd, 2024 05:12

2025 article

Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions

Chmielewski, P. P., Data, K., Strzelec, B., Farzaneh, M., Anbiyaiee, A., Zaheer, U., … Kempisty, B. (2025, June 14). AGING AND DISEASE, Vol. 6.

By: P. Chmielewski n, K. Data, B. Strzelec, M. Farzaneh  n, A. Anbiyaiee, U. Zaheer, S. Uddin, M. Sheykhi-Sabzehpoush ...

author keywords: aging; age-related diseases; geroscience; healthspan; longevity; senescence
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2024

2024 review

Biomimetic Scaffolds-A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

[Review of ]. NANOMATERIALS, 14(6).

By: T. Gornicki *, J. Lambrinow*, A. Golkar-Narenji  n, K. Data *, D. Domagala *, J. Niebora*, M. Farzaneh *, P. Mozdziak n  ...

author keywords: biomimetic scaffolds; 3D bioprinting; biologically derived materials; 4D materials
TL;DR: Increasing amounts of data provide evidence of vast potential of biomimetic scaffolds usage in tissue engineering and personalized medicine, with the main area of potential application being the regeneration of skin and musculoskeletal systems. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 22, 2024

2024 review

Cardiac progenitor cell therapy: mechanisms of action

[Review of ]. CELL AND BIOSCIENCE, 14(1).

By: R. Bryl *, M. Kulus *, A. Bryja*, D. Domagala *, P. Mozdziak n , P. Antosik*, D. Bukowska*, M. Zabel *, P. Dziegiel *, B. Kempisty n

author keywords: Cardiac regeneration; Adult cardiac progenitor cells; Exosomes; Non-coding RNAs
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 1, 2024

2024 review

Cellular, Molecular and Clinical Aspects of Aortic Aneurysm-Vascular Physiology and Pathophysiology

[Review of ]. CELLS, 13(3).

By: D. Domagala *, K. Data *, H. Szyller *, M. Farzaneh *, P. Mozdziak n , S. Wozniak *, M. Zabel*, P. Dziegiel *, B. Kempisty n

author keywords: inflammation; vessel; VSMCs; ECM
TL;DR: The key mechanisms of initiating and promoting AAA are considered to achieve better preventative and therapeutic outcomes and to achieve better preventative and therapeutic outcomes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 6, 2024

2024 journal article

Cross sectional study on exposure to BPA and its analogues and semen parameters in Czech men

ENVIRONMENTAL POLLUTION, 345.

By: M. Jeseta *, J. Kalina *, K. Franzova *, S. Fialkova *, J. Hosek *, L. Mekinova *, I. Crha *, B. Kempisty*, P. Ventruba *, J. Navratilova *

author keywords: Bisphenols; Endocrine disruptors; Human; Spermatozoa; IVF
TL;DR: BPs are widespread in the male population and in case of BPA and BPS having a negative impact on spermiogram parameters are observed, independently of an occupation and in case of BPA and BPS having a negative impact on spermiogram parameters. (via Semantic Scholar)
Source: Web Of Science
Added: March 25, 2024

2024 journal article

New Gene Markers Regulating the Process of Vascularization in Pig Preovulatory Oocytes during Growth and Maturation

JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 38(4), 2807–2824.

By: B. Borowiec, W. Kranc, M. Kulus, P. Sujka-Kordowska, A. Konwerska, P. Celichowski, M. Jozkowiak, J. Kulus ...

author keywords: cumulus-oocyte complexes; cumulus cells; gene ontology; ovary; sus scrofa; VEGFA
Sources: Web Of Science, NC State University Libraries
Added: April 29, 2024

2024 article

Phenotypic Transitions the Processes Involved in Regulation of Growth and Proangiogenic Properties of Stem Cells, Cancer Stem Cells and Circulating Tumor Cells

Kulus, M., Farzaneh, M., Bryja, A., Zehtabi, M., Azizidoost, S., Dari, M. A. G., … Antosik, P. (2024, February 19). STEM CELL REVIEWS AND REPORTS, Vol. 2.

By: M. Kulus *, M. Farzaneh *, A. Bryja *, M. Zehtabi*, S. Azizidoost *, M. Dari*, A. Golcar-Narenji n, H. Ziemak * ...

author keywords: Epithelial-mesenchymal Transition (EMT); Mesenchymal-epithelial Transition (MET); Circulating Tumor cell (CTC); Cancer stem Cells
TL;DR: While EMT is necessary for metastasis, MET is required for CTCs to establish a secondary site, and a thorough understanding of the processes that govern the balance between EMT and MET in malignancy is crucial. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 11, 2024

2023 journal article

Apoptosis Related Human Wharton's Jelly-Derived Stem Cells Differentiation into Osteoblasts, Chondrocytes, Adipocytes and Neural-like Cells-Complete Transcriptomic Assays

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(12).

By: K. Stefanska *, L. Nemcova *, M. Blatkiewicz *, W. Pienkowski*, M. Rucinski *, M. Zabel*, P. Mozdziak n , M. Podhorska-Okolow *, P. Dziegiel *, B. Kempisty n

author keywords: Wharton's jelly; mesenchymal stem cells; RNAseq; MSC; differentiation; apoptosis
TL;DR: In this study, cells were isolated from Wharton’s jelly of umbilical cords obtained from healthy full-term deliveries, cultivated in vitro, and differentiated towards osteogenic, chondrogenic, adipogenic and neurogenic lineages, providing an insight into the molecular mechanisms involved in the long-term culture in vitro and four-lineage differentiation of WJ-MSCs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 13, 2023

2023 review

Bioreactors, scaffolds and microcarriers and in vitro meat production-current obstacles and potential solutions

[Review of ]. FRONTIERS IN NUTRITION, 10.

By: M. Kulus *, M. Jankowski *, W. Kranc *, A. Narenji n, M. Farzaneh *, P. Dziegiel *, M. Zabel *, P. Antosik * ...

author keywords: bioreactor; cultured meat; scaffold; microcarriers; in vitro culture
TL;DR: This review summarizes the most current knowledge regarding the history of cultured meat, the currently used cell sources and methods used for the purpose of in vitro meat production, with particular focus on the role of bioreactors, scaffolds and microcarriers in overcoming the current obstacles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 10, 2023

2023 article

Circular RNAs-mediated angiogenesis in human cancers

Ghaedrahmati, F., Nasrolahi, A., Najafi, S., Mighani, M., Anbiyaee, O., Haybar, H., … Farzaneh, M. (2023, April 11). CLINICAL & TRANSLATIONAL ONCOLOGY.

By: F. Ghaedrahmati *, A. Nasrolahi*, S. Najafi *, M. Mighani*, O. Anbiyaee*, H. Haybar*, A. Assareh *, B. Kempisty* ...

author keywords: circRNAs; Angiogenesis; Tumorigenesis; Diagnosis; Prognosis
TL;DR: The angiogenic impacts and anti-angiogenic managements of circRNAs in human cancers are evaluated and show possibilities to prognosis and diagnosis both in the prophecy of prognosis in malignancies and also their prejudice from healthy individuals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 1, 2023

2023 review

Decellularization of Dense Regular Connective Tissue-Cellular and Molecular Modification with Applications in Regenerative Medicine

[Review of ]. CELLS, 12(18).

By: K. Data *, M. Kulus *, H. Ziemak*, M. Chwarzynski *, H. Piotrowska-Kempisty *, D. Bukowska*, P. Antosik*, P. Mozdziak n , B. Kempisty n

author keywords: tendon; ligament; bioscaffold; extracellular matrix
TL;DR: The wide spectrum of decellularization makes it important to understand the key aspects of bioscaffolds relative to their potential use in tissue regeneration, as well as provide a valuable source of crucial information. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 21, 2023

2023 review

Diagnostic Test Accuracy of Artificial Intelligence in Detecting Periapical Periodontitis on Two-Dimensional Radiographs: A Retrospective Study and Literature Review

[Review of ]. MEDICINA-LITHUANIA, 59(4).

By: J. Issa *, M. Jaber*, I. Rifai *, P. Mozdziak n , B. Kempisty n & M. Dyszkiewicz-Konwinska *

author keywords: artificial intelligence (AI); periapical periodontitis; diagnosis; two-dimensional radiographs; diagnostic test accuracy; automatic detection
MeSH headings : Humans; Retrospective Studies; Artificial Intelligence; Cone-Beam Computed Tomography; Periapical Periodontitis / diagnostic imaging; Periapical Periodontitis / pathology; Diagnostic Tests, Routine
TL;DR: Dicionocat (Diagnocat Ltd., San Francisco, CA, USA) showed an optimum accuracy for detecting periapical periodontitis on periAPical radiographs, but more research is needed to assess the diagnostic accuracy of artificial intelligence-based algorithms in dentistry. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 20, 2023

2023 article

Emerging roles of long non-coding RNA FTX in human disorders

Sheykhi-Sabzehpoush, M., Ghasemian, M., Pour, F. K., Mighani, M., Moghanibashi, M., Jafari, R. M., … Kempisty, B. (2023, April 24). CLINICAL & TRANSLATIONAL ONCOLOGY.

By: M. Sheykhi-Sabzehpoush *, M. Ghasemian *, F. Pour*, M. Mighani*, M. Moghanibashi *, R. Jafari *, M. Zabel *, P. Dziegiel *, M. Farzaneh *, B. Kempisty*

author keywords: Cancer; LncRNAs; FTX; miRNAs; Biomarkers
TL;DR: The emerging roles of FTX in human cancerous and non-cancerous cells are summarized and FTX and its downstream targets may be suitable biomarkers for the diagnosis and treatment of human malignancies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 9, 2023

2023 review

Endocrine Disrupting Chemicals in Polycystic Ovary Syndrome: The Relevant Role of the Theca and Granulosa Cells in the Pathogenesis of the Ovarian Dysfunction

[Review of ]. CELLS, 12(1).

By: M. Jozkowiak *, H. Piotrowska-Kempisty *, D. Kobylarek*, N. Gorska *, P. Mozdziak n , B. Kempisty n, D. Rachon *, R. Spaczynski

author keywords: polycystic ovary syndrome; granulosa cells; theca cells; endocrine disrupting chemicals
MeSH headings : Female; Humans; Polycystic Ovary Syndrome; Endocrine Disruptors / toxicity; Granulosa Cells / pathology
TL;DR: The recent knowledge on PCOS pathophysiology, the role of granulosa and theca cells in PCos pathogenesis, and the evidence linking exposure to EDCs with reproductive disorders such as PCOS are reviewed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 5, 2023

2023 journal article

Expression Profile of New Marker Genes Involved in Differentiation of Human Wharton's Jelly-Derived Mesenchymal Stem Cells into Chondrocytes, Osteoblasts, Adipocytes and Neural-like Cells

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(16).

By: K. Stefanska *, L. Nemcova *, M. Blatkiewicz *, A. Zok *, M. Kaczmarek *, W. Pienkowski*, P. Mozdziak n , H. Piotrowska-Kempisty *, B. Kempisty n

author keywords: Wharton's jelly; mesenchymal stem cells; RNA-seq; MSC; differentiation
TL;DR: Insight is provided into the transcriptomic changes occurring during the differentiation of WJ-MSCs and enables the identification of novel markers involved in this process, which may serve as a reference for further research exploring the role of these genes in physiology of Wj- MSCs and in regenerative medicine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 23, 2023

2023 journal article

Expression of genes regulating cell division in porcine follicular granulosa cells

CELL DIVISION, 18(1).

By: J. Kulus *, W. Kranc *, M. Kulus *, P. Dziegiel *, D. Bukowska*, P. Mozdziak n , B. Kempisty*, P. Antosik*

author keywords: Follicular granulosa cells; Cellular signaling; Cytoskeleton organization; Cell cycle; Gene expression profile; Transcriptomics
TL;DR: The expression profile of selected genes brings new insight into regulation of physiological processes in porcine follicular granulosa cells during primary in vitro culture. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2023 article

In vitro culture of reptile PGCS to preserve endangered species

Golkar-Narenji, A., Dziegiel, P., Kempisty, B., Petitte, J., Mozdziak, P. E., & Bryja, A. (2023, May 13). CELL BIOLOGY INTERNATIONAL, Vol. 5.

By: A. Golkar-Narenji  n, P. Dziegiel *, B. Kempisty n, J. Petitte n , P. Mozdziak n  & A. Bryja*

author keywords: avian; development; embryo; mammals; primordial germ cells; reptiles
MeSH headings : Animals; Endangered Species; Animals, Genetically Modified; Germ Cells; Cell Differentiation; Reptiles; Mammals
TL;DR: It is proposed that a discussion on similarities between reptilian PGCs development with avian and mammalian species helps to find clues for studies of Reptilian P GCs development details and finding an efficient protocol for in vitro culture of reptilian PG. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 30, 2023

2023 journal article

New Gene Markers of Exosomal Regulation Are Involved in Porcine Granulosa Cell Adhesion, Migration, and Proliferation

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(14).

By: J. Kulus *, W. Kranc *, M. Kulus *, D. Bukowska *, H. Piotrowska-Kempisty *, P. Mozdziak n , B. Kempisty n, P. Antosik *

author keywords: porcine granulosa cells; cellular signaling; extracellular vesicles; cell adhesion; cell migration and proliferation; transcriptomics; extracellular matrix
TL;DR: Exosomes may play important roles regarding intercellular signaling between granulosa cells and have significant applications in regenerative medicine, targeted therapy, and assisted reproduction technologies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 29, 2023

2023 review

Non-Invasive Diagnostics of Male Spermatogenesis from Seminal Plasma: Seminal Proteins

[Review of ]. DIAGNOSTICS, 13(15).

By: M. Jeseta *, A. Pospisilova *, L. Mekinova*, K. Franzova *, P. Ventruba *, E. Lousova*, B. Kempisty n, T. Ozdian *, J. Zakova*, I. Crha *

author keywords: spermatozoa; azoospermia; sperm isolation; sperm analyses
TL;DR: The effective using of specific biomarkers from seminal plasma can significantly improve the existing approaches to diagnosis of the causes of male infertility. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 21, 2023

2023 review

Potential roles of endothelial cells-related non-coding RNAs in cardiovascular diseases

[Review of ]. PATHOLOGY RESEARCH AND PRACTICE, 242.

By: S. Azizidoost *, A. Nasrolahi *, M. Sheykhi-Sabzehpoush *, N. Akiash *, A. Assareh *, O. Anbiyaee *, P. Antosik *, P. Dzi *, M. Farzaneh *, B. Kempisty n

author keywords: Long non -coding RNAs; MicroRNAs; Circular RNAs; Endothelial Dysfunction; Cardiovascular diseases
MeSH headings : Humans; Cardiovascular Diseases / genetics; Cardiovascular Diseases / metabolism; Endothelial Cells / pathology; RNA, Long Noncoding / metabolism; Biomarkers / metabolism; Vascular Diseases; MicroRNAs
TL;DR: This review focuses on the expression and functional effects of various kinds of non-coding RNAs in cardiovascular diseases and negotiate their possible clinical implications as diagnostic or prognostic biomarkers and curative targets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 9, 2023

2023 article

Potential roles of lncRNA MALAT1-miRNA interactions in ocular diseases

Nasrolahi, A., Pour, F. K., Salehi, A. M., Kempisty, B., Hajizadeh, M., Feghhi, M., … Farzaneh, M. (2023, October 23). JOURNAL OF CELL COMMUNICATION AND SIGNALING.

By: A. Nasrolahi*, F. Pour*, A. Salehi *, B. Kempisty*, M. Hajizadeh *, M. Feghhi*, S. Azizidoost*, M. Farzaneh *

author keywords: Long non-coding RNAs; MALAT1; Ocular diseases; miRNAs
TL;DR: Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a well-researched lncRNA in the context of ocular diseases, which has been shown to exert its biological effects through several signaling pathways and downstream targets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: November 13, 2023

2023 review

Small extracellular vesicles - A host for advanced bioengineering and "Trojan Horse" of non-coding RNAs

[Review of ]. LIFE SCIENCES, 332.

By: A. Bryja *, L. Zadka *, M. Farzaneh *, M. Zehtabi*, M. Ghasemian *, M. Dyszkiewicz-Konwinska *, P. Mozdziak n , M. Zabel * ...

author keywords: Small extracellular vesicles; Non -coding RNAs; Therapeutic agent; Exosomes; cancer
TL;DR: It is important to consider the fundamental attributes of sEVs and ncRNAs, including by an in-depth analysis of the practical and clinical potentials of exosomes, serving as a representative model for s EVs encapsulating nc RNAs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 27, 2023

2023 article

Steroidogenic activity of liposomal methylated resveratrol analog 3,4,5,4 & PRIME;-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro model

Jozkowiak, M., Kobylarek, D., Bryja, A., Gogola-Mruk, J., Czajkowski, M., Skupin-Mrugalska, P., … Piotrowska-Kempisty, H. (2023, August 12). Steroidogenic activity of liposomal methylated resveratrol analog 3,4,5,4 & PRIME;-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro model. ENDOCRINE.

By: M. Jozkowiak *, D. Kobylarek *, A. Bryja *, J. Gogola-Mruk *, M. Czajkowski *, P. Skupin-Mrugalska *, B. Kempisty n, R. Spaczynski, H. Piotrowska-Kempisty *

author keywords: Human ovarian granulosa cells; Resveratrol; DMU-212; Liposomes; Steroid hormone secretion
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 28, 2023

2023 article

The Mechanisms of Long Non-coding RNA-XIST in Ischemic Stroke: Insights into Functional Roles and Therapeutic Potential

Farzaneh, M., Anbiyaee, O., Azizidoost, S., Nasrolahi, A., Ghaedrahmati, F., Kempisty, B., … Najafi, S. (2023, November 6). MOLECULAR NEUROBIOLOGY, Vol. 11.

By: M. Farzaneh *, O. Anbiyaee*, S. Azizidoost*, A. Nasrolahi*, F. Ghaedrahmati *, B. Kempisty n, P. Mozdziak n , S. Khoshnam *, S. Najafi *

author keywords: Ischemic stroke; LncRNAs; XIST; miRNA; Pathogenesis
TL;DR: A comprehensive summary of the functional roles of X-inactive specific transcript in ischemic stroke is provided, which aims to enhance the understanding of the mechanisms underlying isChemic stroke and potentially identify novel therapeutic targets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 27, 2023

2023 review

The Role of Exosomes in Human Carcinogenesis and Cancer Therapy-Recent Findings from Molecular and Clinical Research

[Review of ]. CELLS, 12(3).

By: K. Stefanska *, M. Jozkowiak *, A. Angelova Volponi *, J. Shibli *, A. Golkar-Narenji  n, P. Antosik*, D. Bukowska*, H. Piotrowska-Kempisty * ...

author keywords: exosomes; cancer; drug resistance; cancer therapies
MeSH headings : Animals; Humans; Exosomes / physiology; Neoplasms / pathology; Drug Carriers / therapeutic use; Drug Delivery Systems; Carcinogenesis; Mammals
TL;DR: It is important to consider the current knowledge regarding the role of exosomes in cancer, drug resistance, cancer therapies, and their clinical application in cancer therapies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 23, 2023

2023 review

The functions of long non-coding RNA (lncRNA)-MALAT-1 in the pathogenesis of renal cell carcinoma

[Review of ]. BMC NEPHROLOGY, 24(1).

By: O. Anbiyaee*, A. Moalemnia*, F. Ghaedrahmati *, M. Shooshtari*, S. Khoshnam *, B. Kempisty*, S. Halili *, M. Farzaneh *, O. Morenikeji *

author keywords: Renal cell carcinoma; lncRNAs; MALAT-1; Biomarker
TL;DR: The potential utility of MALAT-1 as a diagnostic and prognostic biomarker in RCC emerges, warranting further investigation and validation of its clinical significance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: January 8, 2024

2023 review

Unveiling Mesenchymal Stem Cells' Regenerative Potential in Clinical Applications: Insights in miRNA and lncRNA Implications

[Review of ]. CELLS, 12(21).

By: M. Jankowski *, M. Farzaneh *, F. Ghaedrahmati *, M. Shirvaliloo *, A. Moalemnia*, M. Kulus *, H. Ziemak*, M. Chwarzynski * ...

author keywords: mesenchymal stem cells; miRNA; lncRNA
TL;DR: The literature containing the latest discoveries pertaining to human stem cells and their potential in both fundamental research and clinical applications is collected, shedding light on the opportunities presented by harnessing the regulatory potential of miRNAs and lncRNAs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 27, 2023

2022 review

Artificial-Intelligence-Based Imaging Analysis of Stem Cells: A Systematic Scoping Review

[Review of ]. BIOLOGY-BASEL, 11(10).

By: J. Issa, M. Abou Chaar *, B. Kempisty*, L. Gasiorowski, R. Olszewski, P. Mozdziak* , M. Dyszkiewicz-Konwinska

author keywords: artificial intelligence; stem cells; induced pluripotent stem cells; embryonic stem cells; adult stem cells; imaging
TL;DR: This systematic scoping review aimed to identify and map the available artificial-intelligence-based techniques for imaging analysis, the characterization of stem cell differentiation, and trans-differentiation pathways and guide and help researchers while planning for future investigations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 3, 2022

2022 review

Cancer Stem Cells-The Insight into Non-Coding RNAs

[Review of ]. CELLS, 11(22).

By: R. Bryl, O. Piwocka*, E. Kawka, P. Mozdziak n , B. Kempisty n & A. Knopik-Skrocka*

author keywords: cancer stem cells; non-coding RNAs; EMT; phenotypic and metabolic plasticity; anti-cancer therapies
TL;DR: Cancer stem cells have claimed to be one of the most important group of cells for the development of several common cancers as they dictate features, such as resistance to radio- and chemotherapy, metastasis, and secondary tumor formation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 23, 2022

2022 journal article

Cellular Processes in Human Ovarian Follicles Are Regulated by Expression Profile of New Gene Markers-Clinical Approach

JOURNAL OF CLINICAL MEDICINE, 11(1).

By: B. Chermula*, W. Kranc *, P. Celichowski*, B. Stelmach*, H. Piotrowska-Kempisty *, P. Mozdziak n , L. Pawelczyk *, R. Spaczynski *, B. Kempisty n

author keywords: cumulus cells; granulosa cells; human; gene expression; microarray; epithelialization
TL;DR: Detailed analysis of gene expression in these two cell populations at different time intervals confirms their ovarian surface epithelial origin, and some gene expression profiles appear to have tumorigenic properties, suggesting that granulosa cells may play a role in cancerogenesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 29, 2021

2022 journal article

Expression Profile of New Gene Markers Involved in Differentiation of Canine Adipose-Derived Stem Cells into Chondrocytes

GENES, 13(9).

By: M. Jankowski *, M. Kaczmarek *, G. Wasiatycz*, A. Konwerska *, C. Dompe*, D. Bukowska *, P. Antosik *, P. Mozdziak n , B. Kempisty n

author keywords: adipose; stem cells; chondrocytes; differentiation; RNAseq; transcriptomics
MeSH headings : Adipose Tissue / metabolism; Animals; Chondrocytes / metabolism; Culture Media / metabolism; Dogs; Genetic Markers; Matrix Metalloproteinase 12 / metabolism; Osteoarthritis / genetics; Osteoarthritis / metabolism; RNA / metabolism; Stem Cells
TL;DR: The results of the study prove the usefulness of the in vitro culture model, providing further molecular insight into the processes associated with ASC culture and differentiation, and could be used for future in vivo and clinical studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 21, 2022

2022 review

Fetomaternal Expression of Glucose Transporters (GLUTs)-Biochemical, Cellular and Clinical Aspects

[Review of ]. NUTRIENTS, 14(10).

By: R. Sibiak *, K. Ozegowska *, E. Wender-Ozegowska *, P. Gutaj*, P. Mozdziak n  & B. Kempisty n

author keywords: diabetes; glucose transporter proteins; hyperglycemia in pregnancy; placenta; pregnancy
MeSH headings : Biological Transport; Female; Glucose / metabolism; Glucose Transport Proteins, Facilitative / genetics; Glucose Transport Proteins, Facilitative / metabolism; Humans; Placenta / metabolism; Pregnancy; Protein Isoforms
TL;DR: Several types of specialized glucose transporters provide constant glucose transport from the maternal circulation to the developing fetus through the placental barrier from the early stages of pregnancy, and most studies have found no between-group differences in GLUTs’ placental expression in macrosomic and normal control pregnancies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 17, 2022

2022 journal article

The Bisphenols Found in the Ejaculate of Men Does Not Pass through the Testes

TOXICS, 10(6).

By: M. Jeseta *, K. Franzova *, S. Machynova*, J. Kalina *, J. Kohoutek *, L. Mekinova *, I. Crha *, B. Kempisty n ...

author keywords: bisphenol A; bisphenol S; bisphenol F; endocrine disruptors; human; spermatozoa; IVF; vasectomy; biotransformation
TL;DR: Compared normozoospermic men and men after vasectomy who have interrupted vas deferens and their ejaculate does not contain testicular products, it can be concluded that the pathways of transport of bisphenols into seminal plasma are not primarily through the testicular tissue, but this pathway is applied similarly to other routes of transmission by a corresponding ejaculate volume ratio. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 5, 2022

2022 review

The Potential of a Protein Model Synthesized Absent of Methionine

[Review of ]. MOLECULES, 27(12).

By: R. Savino n, B. Kempisty n & P. Mozdziak n 

author keywords: methionine; cysteine; antioxidant; protein; cell; stability; protein synthesis
MeSH headings : Amino Acids; Antioxidants; Cysteine / metabolism; Methionine / chemistry; Proteins / chemistry
TL;DR: A number of novel mechanisms for alternative initiation of protein synthesis have been identified that suggest a potential to bypass the traditional methionine-dependent initiation during times of stress, and a number of examples that demonstrate a potential model for synthesizing a protein in the absence of methamphetamine are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 13, 2022

2022 review

The pathogenic roles of lncRNA-Taurine upregulated 1 (TUG1) in colorectal cancer

[Review of ]. CANCER CELL INTERNATIONAL, 22(1).

By: S. Azizidoost*, A. Nasrolahi*, F. Ghaedrahmati *, B. Kempisty n, P. Mozdziak n , K. Radoszkiewicz *, M. Farzaneh *

author keywords: Colorectal cancer; LncRNAs; TUG1; Tumorigenesis
TL;DR: The scientific literature reports that altered expression of long non-coding RNAs (lncRNAs) contributed to the pathogenesis of CRC cells, and TUG1 might be a potent predictive/prognostic biomarker for diagnosis of CRC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 21, 2022

2022 journal article

Transcriptomic Profile of Genes Regulating the Structural Organization of Porcine Atrial Cardiomyocytes during Primary In Vitro Culture

GENES, 13(7).

By: M. Nawrocki *, K. Jopek *, M. Kaczmarek *, M. Zdun *, P. Mozdziak n , M. Jemielity *, D. Bukowska*, B. Kempisty n, B. Perek *

author keywords: cardiomyocyte structure; cytoskeleton organization; extracellular matrix; cell culture; transcriptomic analysis
MeSH headings : Animals; Collagen / metabolism; Extracellular Matrix / metabolism; Heart Atria; Myocardium / metabolism; Myocytes, Cardiac / metabolism; Swine; Transcriptome
TL;DR: A transcriptomic profile of atrial cardiomyocytes during long-term primary cell culture revealed the expression patterns depending on the duration of the culture and the heart segment of origin (right atrial appendage and right atrium); genes important for cellular architecture, such as ABLIM1, TMOD1, XIRP1, and PHACTR1, were downregulated during in vitro culture. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 10, 2022

2021 journal article

Expression Profile of Genes Encoding Proteins Involved in Regulation of Vasculature Development and Heart Muscle Morphogenesis-A Transcriptomic Approach Based on a Porcine Model

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(16).

By: M. Nawrocki *, K. Jopek *, M. Zdun *, P. Mozdziak n , M. Jemielity *, B. Perek *, D. Bukowska*, B. Kempisty*

author keywords: coronary vessels; neovascularization; cell culture; transcriptomic analysis
MeSH headings : Animals; Cells, Cultured; Coronary Vessels / chemistry; Coronary Vessels / growth & development; Gene Expression Profiling / methods; Gene Expression Regulation, Developmental; Gene Regulatory Networks; Muscle Development; Myocardium / chemistry; Myocardium / cytology; Oligonucleotide Array Sequence Analysis; Primary Cell Culture; Swine; Exome Sequencing
TL;DR: Transcriptomic comparative analysis between two different compartments of the heart muscle allowed us to indicate the presence of differences in the expression of key transcripts depending on the cell source, including SFRP2, PRRX1, and some other genes involved in inflammatory process. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 21, 2021

2021 journal article

Expression Profile of New Gene Markers and Signaling Pathways Involved in Immunological Processes in Human Cumulus-Oophorus Cells

GENES, 12(9).

By: B. Chermula*, G. Hutchings*, W. Kranc *, M. Jozkowiak *, K. Jopek *, B. Stelmach*, P. Mozdziak n , L. Pawelczyk * ...

author keywords: cumulus cells; cytokine action; IVF
MeSH headings : Adult; Cell Proliferation / genetics; Cells, Cultured; Cumulus Cells / immunology; Cumulus Cells / metabolism; Cytokines / metabolism; Female; Fertilization in Vitro; Gene Expression Profiling; Humans; Immunity / genetics; Oocytes / immunology; Oocytes / metabolism; Ovulation / genetics; Ovulation / immunology; Ovulation Induction; Primary Cell Culture; Signal Transduction / genetics; Signal Transduction / immunology; Up-Regulation / immunology
TL;DR: G genes involved in immunological defense processes are upregulated in CC cultures and could serve as useful molecular markers of growth and development in the COC, as well as the proliferation of granulosa and cumulus cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 5, 2021

2021 journal article

Expression Profile of New Marker Genes Involved in Differentiation of Canine Adipose-Derived Stem Cells into Osteoblasts

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(13).

By: M. Jankowski *, M. Kaczmarek *, G. Wasiatycz*, C. Dompe*, P. Mozdziak n , J. Jaskowski *, H. Piotrowska-Kempisty *, B. Kempisty n

author keywords: adipose; stem cells; RNAseq; transcriptome; analysis
MeSH headings : Adipose Tissue / cytology; Animals; Cell Differentiation; Dogs; Gene Expression Profiling; Gene Expression Regulation; Osteoblasts / metabolism; Osteogenesis / genetics; Sequence Analysis, RNA; Stem Cells / metabolism; Stem Cells / physiology; Transcriptome
TL;DR: The results of this study provide molecular insight into the processes that occur during long-term in vitro culture and osteogenic differentiation of ASCs, allowing the re-evaluation of the roles of some genes in MSC progression towards a range of lineages. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 24, 2021

2021 review

Human Granulosa Cells-Stemness Properties, Molecular Cross-Talk and Follicular Angiogenesis

[Review of ]. CELLS, 10(6).

By: C. Dompe*, M. Kulus *, K. Stefanska *, W. Kranc *, B. Chermula*, R. Bryl *, W. Pienkowski*, M. Nawrocki * ...

author keywords: stem cells; granulosa cells; cumulus cells; translational medicine; miRNA; follicular angiogenesis
MeSH headings : Cumulus Cells / metabolism; Female; Humans; Neovascularization, Physiologic; Polycystic Ovary Syndrome / metabolism; Primary Ovarian Insufficiency / metabolism; Stem Cells / metabolism
TL;DR: It is important to carefully consider GCs as ovarian stem cells in terms of the cellular features and molecular pathways involved in their development and interactions as well as outline their possible application in translational medicine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 10, 2021

2021 journal article

Mesenchymal Stem/Stromal Cells Derived from Human and Animal Perinatal Tissues-Origins, Characteristics, Signaling Pathways, and Clinical Trials

CELLS, 10(12).

By: M. Kulus *, R. Sibiak *, K. Stefanska *, M. Zdun *, M. Wieczorkiewicz*, H. Piotrowska-Kempisty *, J. Jaskowski *, D. Bukowska* ...

author keywords: perinatal mesenchymal stem; stromal cells; MSCs differentiation; signaling pathways
MeSH headings : Amniotic Fluid / cytology; Cell Differentiation / genetics; Cell Lineage / genetics; Cell Self Renewal / genetics; Embryonic Stem Cells / cytology; Embryonic Stem Cells / transplantation; Female; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / cytology; Placenta / cytology; Placenta / transplantation; Pregnancy; Regenerative Medicine; Umbilical Cord / cytology; Umbilical Cord / transplantation
TL;DR: It is important to consider the origin of these cells, referring to the anatomical structure of the organs of origin, when describing the general and specific characteristics of the different types of MSCs as well as the pathways involved in differentiation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 28, 2021

2021 review

Molecular Mechanisms Associated with ROS-Dependent Angiogenesis in Lower Extremity Artery Disease

[Review of ]. ANTIOXIDANTS, 10(5).

By: G. Hutchings*, L. Kruszyna *, M. Nawrocki *, E. Strauss *, R. Bryl *, J. Spaczynska*, B. Perek *, M. Jemielity * ...

author keywords: peripheral arterial diseases; angiogenesis; neovascularization; atherosclerosis
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 12, 2021

2021 journal article

New Gene Markers Expressed in Porcine Oviductal Epithelial Cells Cultured Primary In Vitro Are Involved in Ontological Groups Representing Physiological Processes of Porcine Oocytes

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(4).

By: M. Kulus *, W. Kranc *, K. Wojtanowicz-Markiewicz*, P. Celichowski*, A. Swiatly-Blaszkiewicz*, E. Matuszewska *, P. Sujka-Kordowska*, A. Konwerska* ...

author keywords: pig; epithelial cells; microarray assays; long-term in vitro culture; oviduct; transcriptomics; proteomics
MeSH headings : Animals; Cell Differentiation / genetics; Cell Shape / genetics; Cells, Cultured; Down-Regulation / genetics; Epithelial Cells / metabolism; Female; Gene Expression Regulation; Gene Ontology; Gene Regulatory Networks; Genetic Markers; Oocytes / metabolism; Oviducts / cytology; Signal Transduction / genetics; Swine; Transcriptome; Up-Regulation / genetics
TL;DR: The aim of the study was to assess the expression profile of genes in primary in vitro cultured oviductal epithelial cells (OECs), clustered in Gene Ontology groups which enveloped markers also identified in porcine oocytes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 24, 2021

2021 review

Ovarian Cancer and Cancer Stem Cells-Cellular and Molecular Characteristics, Signaling Pathways, and Usefulness as a Diagnostic Tool in Medicine and Oncology

[Review of ]. CANCERS, 13(16).

By: A. Nowicki *, M. Kulus *, M. Wieczorkiewicz*, W. Pienkowski*, K. Stefanska *, P. Skupin-Mrugalska *, R. Bryl *, P. Mozdziak n , B. Kempisty n, H. Piotrowska-Kempisty *

author keywords: ovarian cancer; cancer stem cells; molecular markers; ovarian tumor
TL;DR: Current histological classification of ovarian tumors, their epidemiology, and the most recent knowledge of ovarian CSCs, with particular emphasis on their molecular background, are presented and the importance of signaling pathways involved in tumor growth, development, and metastasis, is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 24, 2021

2021 article

Overview of the Mechanisms of Action of Selected Bisphenols and Perfluoroalkyl Chemicals on the Male Reproductive Axes

Jeseta, M., Navratilova, J., Franzova, K., Fialkova, S., Kempisty, B., Ventruba, P., … Crha, I. (2021, September 27). FRONTIERS IN GENETICS, Vol. 12.

By: M. Jeseta *, J. Navratilova *, K. Franzova *, S. Fialkova *, B. Kempisty n, P. Ventruba *, J. Zakova *, I. Crha *

author keywords: male infertility; spermatogenesis; steroidogenesis; endocrine disrupting chemicals; bisphenol; spermatozoa; perfluoroalkyl substances
TL;DR: This study provides an overview of the mechanisms of action common to persistent (PFAS) and nonpersistent (bisphenols) EDC on male fertility and suggests these chemicals may impact men's fertility through various mechanisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: November 23, 2021

2021 journal article

Photobiomodulation with Red and Near-Infrared Light Improves Viability and Modulates Expression of Mesenchymal and Apoptotic-Related Markers in Human Gingival Fibroblasts

MATERIALS, 14(12).

By: I. Kocherova*, A. Bryja*, K. Blochowiak*, M. Kaczmarek *, K. Stefanska *, J. Matys *, K. Grzech-Lesniak *, M. Dominiak * ...

author keywords: low-level laser treatment; LLLT; photobiomodulation; PBM; human gingival fibroblasts; in vitro
TL;DR: PBM with both 635 and 808 nm at 4 J/cm2 increased the cell number, modulated extracellular oxidative stress and inflammation markers and decreased the susceptibility of human primary gingival fibroblasts to apoptosis through the downregulation of apoptotic-related genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 24, 2021

2021 journal article

Polydioxanone-Based Membranes for Bone Regeneration

POLYMERS, 13(11).

By: S. Saska, L. Pilatti, E. Silva, M. Nagasawa, D. Camara, N. Lizier, E. Finger*, M. Dyszkiewicz Konwinska* ...

author keywords: polydioxanone; membrane; bone regeneration; scaffold
TL;DR: Results revealed that the PDO membranes induced a slightly higher quantity of newly formed bone tissue than the control group without detectable systemic toxicity, showing that Plenum® Guide membranes are a safe and efficient alternative for resorbable membranes for tissue regeneration. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 28, 2021

2021 review

SARS-CoV-2 Genetic Variability and Non-Specific Immunity Associated with the Use of Different BCG Strains-A Molecular and Clinical Approach

[Review of ]. VACCINES, 9(6).

By: J. Kulus *, M. Kulus *, K. Stefanska *, J. Sobolewski *, H. Piotrowska-Kempisty *, P. Mozdziak n , B. Kempisty n

author keywords: SARS-CoV-2; COVID-19; BCG vaccinations; genetic variability; WHO recommendation; variants; tuberculosis
TL;DR: It is remembered that the large variation in the genetic makeup of SARS-CoV-2 may result in future changes in its pathogenicity, immunogenicity and antigenicity, and therefore it is necessary to carefully study the mutations occurring within the virus to determine whether the current vaccines will remain effective. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 16, 2021

2021 journal article

Small Extracellular Vesicles and COVID19-Using the "Trojan Horse" to Tackle the Giant

CELLS, 10(12).

By: B. Borowiec *, A. Angelova Volponi *, P. Mozdziak n , B. Kempisty n & M. Dyszkiewicz-Konwinska *

author keywords: COVID-19; SARS-CoV-2; exosomes; extracellular vesicles
MeSH headings : Animals; COVID-19 / epidemiology; COVID-19 / therapy; COVID-19 / virology; Exosomes / metabolism; Extracellular Vesicles / metabolism; Humans; Models, Biological; SARS-CoV-2 / physiology
TL;DR: The role of EVs in promoting the viral spread by evading the immune response of the host, which is exhibited by retroviruses, indicates the potential for further investigation and possible manipulation of these processes when tackling the spread and treatment of COVID-19. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 6, 2021

2021 journal article

Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells

BIOLOGY-BASEL, 10(11).

By: J. Kulus *, M. Kulus *, W. Kranc *, K. Jopek *, M. Zdun *, M. Jozkowiak *, J. Jaskowski *, H. Piotrowska-Kempisty * ...

author keywords: porcine granulosa cells; extracellular matrix; gene expression profile; folliculogenesis; reproductive physiology
TL;DR: The aim of this study was to describe the expression profile of genes within granulosa cells that are associated with extracellular matrix formation, intercellular signaling, and cell–cell fusion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 25, 2021

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