Works (7)

Updated: January 23rd, 2026 08:10

2025 article

Uterine histotroph and conceptus development. IV. Metabolomic analyses of uterine luminal fluid reveals regulatory landscapes during the peri-implantation period of pregnancy in pigs

Liu, B., Duan, L., Liu, X., Bazer, F. W., & Wang, X. (2025, August 21). Biology of Reproduction.

By: B. Liu n, L. Duan n, X. Liu n, F. Bazer* & X. Wang n

topics (OpenAlex): Reproductive Physiology in Livestock; Reproductive System and Pregnancy
Source: ORCID
Added: September 1, 2025

2023 article

42 Adrenomedullin Stimulates Proliferation, Migration and Adhesion of Porcine Trophectoderm Cells Via CALCRL-AKT-TSC2-MTORC1 Cell Signaling Pathway

Liu, B., Paudel, S., Flowers, W. L., Piedrahita, J. A., & Wang, X. (2023, May 1). Journal of Animal Science, Vol. 101.

By: B. Liu n, S. Paudel n, W. Flowers n, J. Piedrahita n & X. Wang n

author keywords: adrenomedullin; peri-implantation; pig conceptus
topics (OpenAlex): Neuropeptides and Animal Physiology; Cancer, Stress, Anesthesia, and Immune Response
TL;DR: Results suggest that porcine ADM in histotroph act on its receptor component CALCRL to activate AKT-TSC2-MTOR, particularly MTORC1 signaling cascade, leading to elongation, migration and attachment of conceptuses. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024

2023 article

43 Metabolomic Analysis of Uterine Luminal Fluid During the Peri-Implantation Period of Pregnancy in Pigs

Liu, B., Duan, L., Liu, X., & Wang, X. (2023, May 1). Journal of Animal Science, Vol. 101.

By: B. Liu n, L. Duan n, X. Liu n & X. Wang n

author keywords: metabolomics; pig; pregnancy
topics (OpenAlex): Reproductive Physiology in Livestock; Effects of Environmental Stressors on Livestock; Animal Behavior and Welfare Studies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024

2023 article

46 Adrenomedullin: A Novel Peptide Hormone for Uterine Receptivity and Conceptus Elongation in Pigs?

Paudel, S., Liu, B., Cummings, M. J., & Wang, X. (2023, May 1). Journal of Animal Science, Vol. 101.

By: S. Paudel n, B. Liu n, M. Cummings n & X. Wang n

author keywords: conceptuses; implantation; pregnancy
topics (OpenAlex): Neuropeptides and Animal Physiology; Reproductive System and Pregnancy; Immune Response and Inflammation
TL;DR: A significant role for ADM is indicated in uterine receptivity for implantation and conceptus growth and development in pigs, and a framework for future studies of ADM signaling to affect proliferation and migration of Tr cells, spacing of blastocysts, implantations and placentation in pigs is provided. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024

2023 journal article

Uterine histotroph and conceptus development: III. Adrenomedullin stimulates proliferation, migration and adhesion of porcine trophectoderm cells via AKT-TSC2-MTOR cell signaling pathway

Amino Acids, 55(6), 743–756.

By: B. Liu n, S. Paudel n, W. Flowers n, J. Piedrahita n & X. Wang n

author keywords: Adrenomedullin; Trophectoderm cells; MTOR; Pigs; Implantation
MeSH headings : Pregnancy; Female; Swine; Animals; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Adrenomedullin / pharmacology; Signal Transduction; TOR Serine-Threonine Kinases / genetics; TOR Serine-Threonine Kinases / metabolism; Cell Proliferation; Sirolimus / pharmacology
topics (OpenAlex): Neuropeptides and Animal Physiology; Receptor Mechanisms and Signaling; Cancer, Stress, Anesthesia, and Immune Response
TL;DR: Results suggest that porcine ADM in histotroph acts on its receptor component CALCRL to activate AKT-TSC2-MTOR, particularly MTORC1 signaling cascade, leading to elongation, migration and attachment of conceptuses. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: April 24, 2023

2021 article

Temporal and spatial expression of adrenomedullin and its receptors in the porcine uterus and peri-implantation conceptuses

Paudel, S., Liu, B., Cummings, M. J., Quinn, K. E., Bazer, F. W., Caron, K. M., & Wang, X. (2021, June 8). Biology of Reproduction, Vol. 10, pp. 876–891.

author keywords: adrenomedullin; conceptus; uterine fluid; uterus; pigs
MeSH headings : Adrenomedullin / genetics; Adrenomedullin / metabolism; Animals; Embryo, Mammalian / metabolism; Female; Receptors, Adrenomedullin / genetics; Receptors, Adrenomedullin / immunology; Spatio-Temporal Analysis; Sus scrofa / embryology; Sus scrofa / genetics; Uterus / metabolism
topics (OpenAlex): Neuropeptides and Animal Physiology; Neuroendocrine regulation and behavior; Cancer, Stress, Anesthesia, and Immune Response
TL;DR: It is suggested that adrenomedullin plays a significant role in uterine receptivity and conceptus growth and development, via the stimulation of cell proliferation and activation of MTORC1 signaling pathway in the porcine conceptus trophectoderm. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 15, 2021

2019 article

Putrescine mitigates intestinal atrophy through suppressing inflammatory response in weanling piglets

Liu, B., Jiang, X., Cai, L., Zhao, X., Dai, Z., Wu, G., & Li, X. (2019, September 9). Journal of Animal Science and Biotechnology/Journal of Animal Science and Biotechnology.

By: B. Liu*, X. Jiang*, L. Cai*, X. Zhao*, Z. Dai*, G. Wu*, X. Li*

topics (OpenAlex): Polyamine Metabolism and Applications; Biopolymer Synthesis and Applications; Antimicrobial Peptides and Activities
Source: ORCID
Added: January 22, 2026

Employment

Updated: January 22nd, 2026 14:37

2025 - present

North Carolina State University Raleigh, North Carolina, US
Postdoctoral Scholar Animal Science

Education

Updated: January 22nd, 2026 14:37

2019 - 2025

North Carolina State University Raleigh, North Carolina, US
Ph.D. Animal Science

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