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Works (17)
Updated: April 4th, 2024 23:16
2020 article
History of tobacco, vitamin D and women
Manavi, K. R., Alston-Mills, B. P., & Thompson, M. P. (2020, October). INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH, Vol. 90, pp. 389–394.
author keywords: Smoking; tobacco; vitamin D; women
MeSH headings : Cotinine / metabolism; Female; Humans; Tobacco; Tobacco Smoke Pollution; Vitamin D / metabolism; Vitamins / chemistry
TL;DR:
Exposure to environmental tobacco smoke has been associated with reduced levels of Vitamin D in the blood stream and sinus tissues, and Manavi et al. (2015) demonstrated that among three smoking categories (heavy, light, non-smokers), black female heavy smokers have lower vitamin D than Hispanic or white females correlating to higher levels of cotinine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: November 2, 2020
2015 journal article
Effect of serum cotinine on vitamin D serum concentrations among American females with different ethnic backgrounds
Anticancer Research, 35(2), 1211–1218.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Modulation of mammary gland development in pre-pubertal mice as affected by soya and milk protein supplements
BRITISH JOURNAL OF NUTRITION, 106(4), 502–509.
author keywords: alpha-Lactalbumin; Soya; Mouse mammary development; Extracellular matrix
MeSH headings : Animals; Breast Neoplasms / prevention & control; Caseins / administration & dosage; Caseins / adverse effects; Caseins / therapeutic use; DNA / metabolism; Epidermal Growth Factor / metabolism; Estradiol / administration & dosage; Estradiol / blood; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / adverse effects; Estrogens, Non-Steroidal / therapeutic use; Extracellular Matrix Proteins / metabolism; Female; Lactalbumin / administration & dosage; Lactalbumin / adverse effects; Lactalbumin / therapeutic use; Mammary Glands, Animal / cytology; Mammary Glands, Animal / growth & development; Matrix Metalloproteinase 2 / metabolism; Mice; Mice, Transgenic; Milk Proteins / administration & dosage; Milk Proteins / adverse effects; Milk Proteins / therapeutic use; Phytoestrogens / administration & dosage; Phytoestrogens / adverse effects; Phytoestrogens / therapeutic use; Random Allocation; Receptor, ErbB-2 / genetics; Soybean Proteins / administration & dosage; Soybean Proteins / adverse effects; Soybean Proteins / therapeutic use; Tissue Inhibitor of Metalloproteinase-2 / metabolism; Weaning; Whey Proteins
TL;DR:
The mechanism by which α-LA affects glandular development is by modulating the ECM or by promoting the synthesis/activity of EGF, which is known to be oestrogenic and can act on epithelia directly.
(via Semantic Scholar)
open access via www.cambridge.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
The Dietary Compounds Resveratrol and Genistein Induce Activating Transcription Factor 3 While Suppressing Inhibitor of DNA Binding/Differentiation-1
JOURNAL OF MEDICINAL FOOD, 14(6), 584–593.
author keywords: activating transcription factor 3; colorectal cancer; genistein; inhibitor of DNA binding/differentiation-1; microarray; polyphenolics; resveratrol
MeSH headings : Activating Transcription Factor 3 / genetics; Activating Transcription Factor 3 / metabolism; Cell Line, Tumor; Colorectal Neoplasms / diet therapy; Colorectal Neoplasms / genetics; Colorectal Neoplasms / metabolism; Down-Regulation / drug effects; Genistein / pharmacology; Humans; Inhibitor of Differentiation Protein 1 / genetics; Inhibitor of Differentiation Protein 1 / metabolism; Resveratrol; Stilbenes / pharmacology; Up-Regulation / drug effects
TL;DR:
Human colorectal cancer cells were treated with resveratrol and genistein, and their expression was determined, and ATF3 was induced, and Id1 was repressed, by these compounds and by sulindac sulfide, a positive control, at the mRNA and protein level.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Research ethics education: beyond RCR training
FCTL Newsletter, 2, 1–4.
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
Determination of membrane lipid differences in insulin resistant diabetes mellitus type 2 in whites and blacks
NUTRITION, 22(11-12), 1096–1102.
author keywords: diabetes; membrane lipids; insulin resistance; red blood cell deformability; fatty acids; membrane fluidity
MeSH headings : Adult; Black People; Blood Glucose / metabolism; Cholesterol / blood; Diabetes Mellitus, Type 2 / blood; Diabetes Mellitus, Type 2 / metabolism; Erythrocyte Membrane / chemistry; Erythrocyte Membrane / metabolism; Erythrocytes / metabolism; Fatty Acids / analysis; Fatty Acids, Unsaturated / analysis; Female; Humans; Insulin / blood; Insulin Resistance; Lipids / blood; Male; Membrane Lipids / analysis; Membrane Lipids / blood; Membrane Lipids / chemistry; Middle Aged; White People
TL;DR:
The combination of increased saturated/polyunsaturated fatty acids, increased saturated nature, and increased cholesterol/phospholipid can contribute to decreased membrane fluidity, resulting in insulin resistance, which may be one of the reasons for a higher incidence of diabetes among blacks.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
beta-lactoglobulin as a potential modulator of intestinal activity and morphology in neonatal piglets
ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY, 288A(6), 601–608.
author keywords: beta-lactoglobulin; intestinal; enzyme; DNA; morphology
MeSH headings : Alkaline Phosphatase / analysis; Alkaline Phosphatase / metabolism; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Animals, Suckling; Colostrum / chemistry; Colostrum / metabolism; DNA / analysis; DNA / metabolism; Dietary Supplements; Intestinal Mucosa / metabolism; Intestines / drug effects; Intestines / growth & development; Lactase / analysis; Lactase / metabolism; Lactoglobulins / administration & dosage; Lactoglobulins / pharmacology; Microtomy; Staining and Labeling; Swine / growth & development; Swine / metabolism; Weight Gain / drug effects; alpha-Glucosidases / analysis; alpha-Glucosidases / metabolism
TL;DR:
Sow-reared piglets had the greatest intestinal morphology development with regards to villus height and no significant differences were found in enzymatic activity between treatments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3)
MOLECULAR CANCER THERAPEUTICS, 4(5), 693–703.
MeSH headings : Activating Transcription Factor 3; Allyl Compounds / pharmacology; Animals; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Apoptosis / drug effects; Chromans / pharmacology; Colorectal Neoplasms / metabolism; Colorectal Neoplasms / pathology; Cyclooxygenase Inhibitors / pharmacology; Disulfides / pharmacology; Gene Expression Regulation, Enzymologic / drug effects; Gene Expression Regulation, Neoplastic / drug effects; HCT116 Cells; Humans; Male; Mice; Mice, Nude; Microarray Analysis; Neoplasm Invasiveness / pathology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Resveratrol; Stilbenes / pharmacology; Sulindac / analogs & derivatives; Sulindac / pharmacology; Thiazolidinediones / pharmacology; Transcription Factors / genetics; Transcription Factors / metabolism; Transplantation, Heterologous; Troglitazone; Up-Regulation
TL;DR:
ATF3 represents a novel mechanism in which NSAIDs exert their anti-invasive activity, thereby linking ATF3 and its gene regulatory activity to the biological activity of these compounds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene
Journal of Pharmacology and Experimental Therapeutics, 315(2), 668–677.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
Estrogen response element and the promoter context of the human and mouse lactoferrin genes influence estrogen receptor alpha-mediated transactivation activity in mammary gland cells
Journal of Molecular Endocrinology, 33(2), 315–334.
Source: NC State University Libraries
Added: August 6, 2018
2003 journal article
Can anthropometric measurements and diet analysis serve as useful tools to determine risk factors for insulin-resistant diabetes type 2 among white and black Americans?
NUTRITION, 19(7-8), 584–588.
author keywords: insulin resistance; diabetes; anthropometric measurements; ethnicity; diet analysis
MeSH headings : Abdomen; Adipose Tissue; Adult; Anthropometry; Black People; Body Composition; Body Constitution; Body Mass Index; Diabetes Mellitus / epidemiology; Diabetes Mellitus / ethnology; Diabetes Mellitus, Type 2 / epidemiology; Diabetes Mellitus, Type 2 / ethnology; Feeding Behavior; Female; Humans; Insulin Resistance / physiology; Male; Middle Aged; Obesity; Risk Factors; White People
TL;DR:
Diet analysis when used in conjunction with anthropometric measurements can serve as a useful tool to detect whether metabolic alterations are related to dietary habits, and researchers should consider anatomic differences among different racial groups as covariables.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells
CARCINOGENESIS, 25(3), 349–357.
MeSH headings : Apoptosis / drug effects; Carcinoma / enzymology; Carcinoma / genetics; Carcinoma / metabolism; Cell Division / drug effects; Colorectal Neoplasms / enzymology; Colorectal Neoplasms / genetics; Colorectal Neoplasms / metabolism; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors / pharmacology; Gene Expression Regulation, Neoplastic / drug effects; Humans; Isoenzymes / antagonists & inhibitors; Isoenzymes / drug effects; Membrane Proteins; Prostaglandin-Endoperoxide Synthases / drug effects; Pyrazoles / pharmacology; Tumor Cells, Cultured
TL;DR:
This is the first report to suggest that like sulindac sulfide, the Cox-1 specific inhibitor SC-560 appears to elicit chemo-preventative activity by altering gene expression, while the Chemo-Preventative effects of SC-58125 are complex and probably work through these and other mechanisms, such as the inhibition of Cox-2.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
A comparison of the composition of milks from Meishan and crossbred pigs
LIVESTOCK PRODUCTION SCIENCE, 63(1), 85–91.
author keywords: milk composition; Meishan; pig; solvation
TL;DR:
Examination of litter characteristics, milk composition including calcium and the water holding capacity of casein, solvation between the highly prolific Meishan breed and lean crossbred pigs found milk from Meishans might provide an early advantage to improve survivability of piglets by supplying more fat and higher calcium for bone development than traditional breeds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Factors influencing maternal behavior in the hubb/hubb mutant mouse
PHYSIOLOGY & BEHAVIOR, 68(1-2), 3–8.
author keywords: dopamine; maternal behavior; mice; hubb/hubb; tyrosine hydroxylase
MeSH headings : 3,4-Dihydroxyphenylacetic Acid / metabolism; Animals; Brain Mapping; Cannibalism; Dopamine / physiology; Female; Lactation / physiology; Maternal Behavior / physiology; Median Eminence / anatomy & histology; Median Eminence / physiology; Mice; Mice, Inbred ICR; Mice, Neurologic Mutants; Pregnancy; Prolactin / metabolism; Tyrosine 3-Monooxygenase / physiology
TL;DR:
Dopamine was similar in both strains at all stages, but DOPAC was significantly higher at early lactation in the mutants, and it is likely that the increase in DopAC in the mutant reflects a decrease in prolactin, which could contribute to the diminished maternal care in the mutations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 personal communication
Alpha-lactalbumin as a modulator of mammary cellular activity
MeSH headings : Animals; Cell Division / drug effects; Cell Line, Transformed; Culture Media; Culture Techniques; DNA / metabolism; Female; Glucocorticoids; Insulin; Lactalbumin / pharmacology; Mammary Glands, Animal / drug effects; Mammary Glands, Animal / physiology; Mice; Pregnancy; Prolactin; Proteins / metabolism
TL;DR:
The purpose was to determine whether c~-LA, used as a supplement, would effect total protein and DNA concentrations in mammary explants from mid-pregnant mice cultured in the presence of insulin, prolactin, and gtucocorticoids.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
1997 article
Effects of whey-milk proteins on Caco-2 and HT-29 intestinal cell lines
AlstonMills, B., Allen, J. C., Sternhagen, L., & Hepler, C. D. (1997, October 1). LIVESTOCK PRODUCTION SCIENCE, Vol. 50, pp. 147–148.
TL;DR:
Cell proliferation assays showed that α-LA consistently increased cell replication rate with a peak response at approximately 20 ng/mL, and higher concentrations were either less effective or ineffective growth stimulators in both cell lines.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1996 journal article
A theoretical approach to possible biological functions of the milk-whey proteins, alpha-lactalbumin and beta-lactoglobulin
Comments on Agricultural and Food Chemistry, 3(3), 175.
Source: NC State University Libraries
Added: August 6, 2018
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