Works (12)
Updated: November 21st, 2024 05:01
2024 article
Overcoming the effects of fluid shear stress in ovarian cancer cell lines: Doxorubicin alone or photodynamic priming to target platinum resistance
Overchuk, M., Rickard, B. P., Tulino, J., Tan, X., Ligler, F. S., Huang, H.-C., & Rizvi, I. (2024, June 7). PHOTOCHEMISTRY AND PHOTOBIOLOGY, Vol. 6.
author keywords: benzoporphyrin derivative; cisplatin; doxorubicin; high-grade serous ovarian carcinoma; ovarian cancer; photodynamic priming
open access via onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 17, 2024
2024 article
PpIX-enabled fluorescence-based detection and photodynamic priming of platinum-resistant ovarian cancer cells under fluid shear stress
Ruhi, M. K., Rickard, B. P., Overchuk, M., Sinawang, P. D., Stanley, E., Mansi, M., … Rizvi, I. (2024, August 27). PHOTOCHEMISTRY AND PHOTOBIOLOGY, Vol. 8.
author keywords: fluid shear stress; ovarian cancer; photodynamic priming; platinum resistance; protoporphyrin IX
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 9, 2024
2023 journal article
Exposure to select PFAS and PFAS mixtures alters response to platinum-based chemotherapy in endometrial cancer cell lines
Environmental Health, 22(1).
author keywords: PFAS; Endometrial cancer; Therapy resistance; Carboplatin; Cisplatin; Mitochondria
TL;DR:
Investigation of the effect of environmental exposures, specifically PFAS, on platinum-based chemotherapy response and mitochondrial function in endometrial cancer suggests that PFAS exposure may affect endometrial cancer cell mitochondrial functioning.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
6. Clean Water and Sanitation
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: January 2, 2024
2023 journal article
Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer
Cancers, 15(9), 2564.
author keywords: mitochondrial methods; bioenergetics; mitochondrial dysfunction; reactive species; mitochondrial function; mitochondrial structure; extracellular vesicles
TL;DR:
Methods to evaluate the structural and functional parameters of mitochondrial health in the context of tumors and cancer cells are discussed, with a particular emphasis on gynecologic malignancies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: May 30, 2023
2022 journal article
A High-Throughput Toxicity Screen of 42 Per- and Polyfluoroalkyl Substances (PFAS) and Functional Assessment of Migration and Gene Expression in Human Placental Trophoblast Cells
Frontiers in Toxicology, 4.
Sources: ORCID, Crossref, NC State University Libraries
Added: September 4, 2024
2022 chapter
Integrins in Ovarian Cancer: Survival Pathways, Malignant Ascites and Targeted Photochemistry
In Recent Advances, New Perspectives and Applications in the Treatment of Ovarian Cancer.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 19, 2024
2022 journal article
Photochemical Targeting of Mitochondria to Overcome Chemoresistance in Ovarian Cancer<sup>†
Photochemistry and Photobiology, 99(2), 448–468.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: October 31, 2022
2022 journal article
Photodynamic Priming Overcomes Per‐ and Polyfluoroalkyl Substance (<scp>PFAS
Photochemistry and Photobiology, 99(2), 793–813.
Sources: ORCID, Crossref, NC State University Libraries
Added: July 15, 2024
2022 journal article
Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines
International Journal of Molecular Sciences, 23(9), 5176.
author keywords: per- and polyfluoroalkyl substances; PFAS; ovarian cancer; platinum resistance; carboplatin; mitochondrial function
MeSH headings : Alkanesulfonic Acids / toxicity; Carboplatin / pharmacology; Carcinoma, Ovarian Epithelial; Cell Line; Environmental Pollutants / toxicity; Female; Fluorocarbons / toxicity; Humans; Ovarian Neoplasms / drug therapy
TL;DR:
This is the first study to demonstrate that, at sub-cytotoxic concentrations, select PFAS and PFAS mixtures increased survival fraction in ovarian cancer cells following carboplatin treatment, indicative of platinum resistance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
6. Clean Water and Sanitation
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: May 23, 2022
2021 journal article
E-Cigarette Flavoring Chemicals Induce Cytotoxicity in HepG2 Cells
ACS Omega, 6(10), 6708–6713.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 19, 2024
2021 review
Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response
[Review of ]. CANCERS, 13(17).
author keywords: malignant ascites; epithelial ovarian cancer; chemoresistance; mechanical stress; flow-induced shear stress; photodynamic therapy; tumor microenvironment; transcoelomic metastases; tumor heterogeneity; epithelial to mesenchymal transition
TL;DR:
The current understanding of malignant ascites is summarized, starting with an overview of ovarian cancer and ascites, followed by a description of the tools used to analyze the components of ascites and how these components modulate ovarian cancer biology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 20, 2021
2021 journal article
Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease
Toxicology, 465, 153031.
author keywords: PFAS; Female reproduction; Environmental contaminants; Endocrine disruption
MeSH headings : Endocrine Disruptors / adverse effects; Endocrine System Diseases / chemically induced; Endocrine System Diseases / metabolism; Endocrine System Diseases / physiopathology; Environmental Exposure / adverse effects; Environmental Pollutants / adverse effects; Female; Fertility / drug effects; Humans; Hydrocarbons, Fluorinated / adverse effects; Infertility, Female / chemically induced; Infertility, Female / metabolism; Infertility, Female / physiopathology; Menstrual Cycle / drug effects; Pregnancy; Pregnancy Complications / chemically induced; Pregnancy Complications / metabolism; Pregnancy Complications / physiopathology; Prognosis; Reproduction / drug effects; Risk Assessment; Risk Factors
TL;DR:
The role of a variety of PFAS and PFAS mixtures in female reproductive tract dysfunction and disease is summarized and the role ofPFAS in breast, thyroid, and hypothalamic-pituitary-gonadal axis function is discussed as the interplay between these tissues may be critical in understanding the long-term reproductive health effects of PFas in women.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: November 29, 2021
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