Works (63)
Updated: April 4th, 2024 12:18
2023 journal article
Systems and methods for authenticating manufacturing Machines through an unobservable fingerprinting system
Manufacturing Letters, 35, 1009–1018.
author keywords: Cybersecurity; Connected Manufacturing; Authentication; Physical Unclonable Function; Digital Twin; Vibration
Sources: Web Of Science, ORCID, Crossref
Added: October 16, 2023
2023 journal article
“Unreal” factories: Next generation of digital twins of machines and factories in the Industrial Metaverse
Manufacturing Letters, 37, 50–52.
author keywords: Digital twins; Digital fabrication; Computational fabrication; Smart manufacturing; Industry 4; 0
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, Crossref, ORCID
Added: September 5, 2023
2022 journal article
Knowledge graph construction for product designs from large CAD model repositories
ADVANCED ENGINEERING INFORMATICS, 53.
author keywords: Digital manufacturing; 3D shape search; 3D recommendation; Deep learning
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID
Added: July 26, 2022
2021 article
"FabNER": information extraction from manufacturing process science domain literature using named entity recognition
Kumar, A., & Starly, B. (2021, June 24). JOURNAL OF INTELLIGENT MANUFACTURING, Vol. 6.
Contributors: A. Kumar n & n
author keywords: NER; Technical language processing; TLP; Word2Vec; Topic modeling
TL;DR:
This work presents a supervised machine learning approach to categorize unstructured text from 500K+ manufacturing science related scientific abstracts and labelling them under various manufacturing topic categories, using the developed NER model as a Technical Language Processing (TLP) workflow on manufacturing science documents.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: June 24, 2021
2021 article
A genetic algorithm for order acceptance and scheduling in additive manufacturing
Kapadia, M. S., Uzsoy, R., Starly, B., & Warsing, D. P., Jr. (2021, October 23). INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH, Vol. 10.
author keywords: Order acceptance scheduling; genetic algorithms; additive manufacturing; statistical optimum estimation; batch machine scheduling
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID
Added: November 8, 2021
2021 journal article
Dynamic matching with deep reinforcement learning for a two-sided Manufacturing-as-a-Service (MaaS) marketplace
MANUFACTURING LETTERS, 29, 11–14.
author keywords: Cloud manufacturing; Cyber-enabled manufacturing; Resource allocation; Two-sided matching; Dynamic and stochastic knapsack problem (DSKP); Cloud based design and manufacturing (CBDM)
TL;DR:
Empirical simulations demonstrate that DRL has considerably better performance compared to four baselines and demonstrates a learning approach for near real-time decision making for suppliers participating in a MaaS marketplace.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
16. Peace, Justice and Strong Institutions
(OpenAlex)
Sources: Web Of Science, ORCID
Added: October 4, 2021
2021 article
Hybrid Blockchain Architecture for Cloud Manufacturing-as-a-service (CMaaS) Platforms with Improved Data Storage and Transaction Efficiency
49TH SME NORTH AMERICAN MANUFACTURING RESEARCH CONFERENCE (NAMRC 49, 2021), Vol. 53, pp. 594–605.
author keywords: blockchain; smart contracts; distributed database; time series; regression; lstm; gas price prediction
TL;DR:
A Random Forest regressor based time series inference model has been shown to exhibit superior performance in the prediction of Ethereum gas price, that allows the CMaaS to avoid executing transactions in periods of high gas prices within the Ethereum ecosystem.
(via Semantic Scholar)
doi.org (publisher)
Sources: Web Of Science, ORCID
Added: October 24, 2022
2021 journal article
MVCNN plus plus : Computer-Aided Design Model Shape Classification and Retrieval Using Multi-View Convolutional Neural Networks
JOURNAL OF COMPUTING AND INFORMATION SCIENCE IN ENGINEERING, 21(1).
TL;DR:
The proposed algorithm (MVCNN++) builds on the MVCNN algorithm with the addition of part dimension data, improving its efficacy for manufacturing part classification and yielding an improvement in classification accuracy of 5.8% over the original version.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(OpenAlex)
Sources: Web Of Science, ORCID
Added: February 8, 2021
2021 article
Non-destructive quality monitoring of 3D printed tissue scaffolds via dielectric impedance spectroscopy and supervised machine learning
49TH SME NORTH AMERICAN MANUFACTURING RESEARCH CONFERENCE (NAMRC 49, 2021), Vol. 53, pp. 636–643.
author keywords: biofabrication; non-destructive quality monitoring; supervised machine learning; dielectric impedance spectroscopy; tissue engineering
Sources: Web Of Science, ORCID
Added: April 20, 2022
2021 journal article
Recurrent neural networks with long term temporal dependencies in machine tool wear diagnosis and prognosis
SN APPLIED SCIENCES, 3(4).
author keywords: Recurrent neural networks; Long term temporal dependencies; Long short term memory; Tool wear; Remaining useful life
TL;DR:
A recent deep learning method, including Long Short Term Memory (LSTM), which try to captures long-term dependencies than regular Recurrent Neural Network method for modeling sequential data, and also the mechanism to realize the online diagnosis and prognosis and remaining useful life (RUL) prediction with indirect measurement collected during the manufacturing process is proposed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: April 19, 2021
2020 journal article
Automating the Search and Discovery of Manufacturing Service Providers to Enable a Digital Supply Chain Network
SMART AND SUSTAINABLE MANUFACTURING SYSTEMS, 4(3), 276–280.
author keywords: coronavirus disease; manufacturing search engine optimization; schema.org vocabulary extensions; blockchain
TL;DR:
This technical note outlines solution pathways that can help ease the search and discovery process of connecting clients and manufacturing service providers through digitally enabled technologies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID
Added: January 4, 2021
2020 journal article
Decentralized cloud manufacturing-as-a-service (CMaaS) platform architecture with configurable digital assets
JOURNAL OF MANUFACTURING SYSTEMS, 56, 157–174.
author keywords: Cybermanufacturing; Blockchain; Smart contracts; Distributed digital thread; Cloud manufacturing
TL;DR:
The design, implementation and validation of middleware software architectures which aim to directly connect client users with manufacturing service providers while improving transparency, data integrity, data provenance and retaining data ownership to its creators are reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science; OpenAlex)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID
Added: October 12, 2020
2020 journal article
The bioprinting roadmap
BIOFABRICATION, 12(2).
author keywords: biofabrication; bioprinting; cell printing; in vitro biological models; disease models; organoids; organ-on-a-chip
MeSH headings : Animals; Bioprinting / methods; Bioprinting / trends; Humans; Tissue Engineering / instrumentation; Tissue Scaffolds / chemistry
TL;DR:
This bioprinting roadmap features salient advances in selected applications of the technique and highlights the status of current developments and challenges, as well as envisioned advances in science and technology, to address the challenges to the young and evolving technique.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
Sources: Web Of Science, ORCID
Added: June 8, 2020
2020 journal article
Witness Box Protocol: Automatic machine identification and authentication in industry 4.0
COMPUTERS IN INDUSTRY, 123.
author keywords: Cybersecurity; Smart manufacturing; Manufacturing fingerprinting; Cyber physical systems; Digital supply Chain traceability
TL;DR:
This paper introduces a machine fingerprinting scheme named as the ‘Witness Box Protocol’ (WBP) that exploits the physical properties of manufacturing machines and their surroundings to create a unique biometric like fingerprint that simplifies asset management within a large enterprise or distributed network comprising of thousands of machines in a Manufacturing-as-a-Service (MaaS) paradigm.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID
Added: July 19, 2021
2019 article
Integrating A Dynamic Simulator and Advanced Process Control using the OPC-UA Standard
47TH SME NORTH AMERICAN MANUFACTURING RESEARCH CONFERENCE (NAMRC 47), Vol. 34, pp. 813–819.
author keywords: OPC-UA; Simulation; Advanced Process Control; Integration; Automation
TL;DR:
This case study is a proof of concept of the OPC-UA standard implementation to support interoperability for different domains and established the client and server for communication and defined an exchange data structure based on the O PC- UA standard for a control problem in a chemical process plant.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID
Added: September 7, 2020
2019 journal article
Network-based pricing for 3D printing services in two-sided manufacturing-as-a-service marketplace
Rapid Prototyping Journal, ahead-of-print(ahead-of-print).
author keywords: Data mining; Sharing economy; Machine learning; Manufacturing-as-a-service; Network-based pricing
TL;DR:
This paper presents approaches to determine a network-based pricing for 3D printing services in the context of a two-sided manufacturing-as-a-service marketplace to enable service bureaus to better compete in the market by moving away from setting ad hoc and subjective prices.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
Sources: Crossref, ORCID
Added: September 8, 2019
2019 article
Provisioned Data Distribution for Intelligent Manufacturing via Fog Computing
47TH SME NORTH AMERICAN MANUFACTURING RESEARCH CONFERENCE (NAMRC 47), Vol. 34, pp. 893–902.
author keywords: Fog Computing; MTConnect Industry 4.0; IIoT; Industrial Cyber-Physical Systems; Big Data; Digital Manufacturing; Data Distribution
TL;DR:
This paper proposes a decentralized data distribution architecture to democratize the potential availability of large amounts of data generated by the manufacturing industry using the Fog Computing paradigm, and demonstrates a data-centric approach which allows peer-to-peer data sharing laterally within the fog layer to serve cloud users.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID
Added: September 7, 2020
2019 journal article
“FabSearch”: A 3D CAD Model-Based Search Engine for Sourcing Manufacturing Services
Journal of Computing and Information Science in Engineering, 19(4).
author keywords: cybermanufacturing; manufacturing search engine; matching manufacturers; shape search; CAD search
TL;DR:
The potential for utilizing the rich information contained within a 3D part model to automate the sourcing and eventual selection of manufacturing service providers is shown for the first time.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
2018 journal article
A Case Study for Blockchain in Manufacturing: “FabRec”: A Prototype for Peer-to-Peer Network of Manufacturing Nodes
Procedia Manufacturing, 26, 1180–1192.
author keywords: blockchain; cyber-physical systems; smart contracts; ethereum; decentralized networks; shareable databases
TL;DR:
The proposed FabRec system decentralizes critical information about the manufacturer and makes it available on a peer-to-peer network composed of fiduciary nodes to ensure transparency and data provenance through a verifiable audit trail.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 25, 2020
2018 journal article
Label free process monitoring of 3D bioprinted engineered constructs via dielectric impedance spectroscopy
BIOFABRICATION, 10(3).
author keywords: FDA PAT; Process Analytical Technology; bioprinting process parameters; biofabrication process monitoring; quality assessment
MeSH headings : Bioprinting / standards; Cell Line; Cell Survival / physiology; Cells, Cultured; Dielectric Spectroscopy / methods; Humans; Materials Testing / methods; Printing, Three-Dimensional; Stem Cells / cytology; Tissue Engineering / standards
TL;DR:
The findings of this study support the use of dielectric impedance spectroscopy as a label-free and non-destructive method to characterize the critical quality attributes of bioprinted constructs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Large-scale digitization of herbarium specimens: Development and usage of an automated, high-throughput conveyor system
TAXON, 67(1), 165–178.
author keywords: automation; biodiversity informatics; digitization; herbarium specimens; imaging; New England; transcription; workflows
TL;DR:
To create a dataset for the study of global change in New England, an industrial-scale, conveyor-based digitization workflow for herbarium specimen sheets is designed and implemented and demonstrated that it is possible to capture both an image of a specimen and a core database record in 35 seconds per her barium sheet.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Reverse auction mechanism design for the acquisition of prototyping services in a manufacturing-as-a-service marketplace
JOURNAL OF MANUFACTURING SYSTEMS, 48, 134–143.
author keywords: Distributed manufacturing; Reverse auction; Mechanism design; Name Your Own Price (TM)
UN Sustainable Development Goal Categories
10. Reduced Inequalities
(Web of Science)
Sources: Web Of Science, ORCID
Added: November 5, 2018
2017 journal article
A flexible data schema and system architecture for the virtualization of manufacturing machines (VMM)
Journal of Manufacturing Systems, 45, 236–247.
author keywords: Cyber-physical manufacturing; Smart manufacturing; Digital twins; MongoDB; NoSQL
TL;DR:
This paper describes how streaming data can be stored in a scalable and flexible document schema based database such as MongoDB, a data store that makes up the virtual twin system that results in the virtualization of a machine resource to external factory manufacturing systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Crossref, ORCID
Added: September 13, 2019
2017 journal article
Electrical Cell-Substrate Impedance Spectroscopy Can Monitor Age-Grouped Human Adipose Stem Cell Variability During Osteogenic Differentiation
STEM CELLS TRANSLATIONAL MEDICINE, 6(2), 502–511.
author keywords: Electrical cell-substrate impedance spectroscopy; Adipose stem cells; Osteogenesis; Bioimpedance
MeSH headings : Adipose Tissue / cytology; Adult; Age Factors; Aged; Aged, 80 and over; Bone and Bones / cytology; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dielectric Spectroscopy / methods; Electric Impedance; Humans; Middle Aged; Osteogenesis; Phenotype; Stem Cells / metabolism; Stem Cells / physiology; Time Factors; Young Adult
TL;DR:
This is the first study to use ECIS to predict osteogenic potential of multiple hASC populations and to show that donor age may temporally control onset of osteogenesis, which could be critical for development of patient‐specific bone tissue engineering and regenerative medicine therapies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 article
Human Mesenchymal Stem Cells Expansion on Three-Dimensional (3D) Printed Poly-Styrene (PS) Scaffolds in a Perfusion Bioreactor
3RD CIRP CONFERENCE ON BIOMANUFACTURING, Vol. 65, pp. 115–120.
author keywords: Mesenchymal Stem Cells (MSCs); Cell Expansion Bioreactor; Poly-Styrene Scaffolds; Perfusion culture; 3D culture; Differentiation
TL;DR:
A novel approach of expanding Adipose derived hMSCs (human Mesenchymal Stem Cells) seeded on 3D printed Poly-Styrene scaffolds within a perfusion based cell expansion bioreactor resulted in comparable fold-expansion and viability.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 conference paper
Investigating dielectric impedance spectroscopy as a non-destructive quality assessment tool for 3D cellular constructs
Proceedings of the ASME 12th International Manufacturing Science and Engineering Conference - 2017, vol 4.
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Particle learning in online tool wear diagnosis and prognosis
JOURNAL OF MANUFACTURING PROCESSES, 28, 457–463.
author keywords: Particle learning; Tool wear; Intelligent manufacturing; Remaining useful life (RUL)
TL;DR:
A probabilistic method based on a Particle Learning (PL) approach by building a linear system transition function whose parameters are updated through online in-process observations of the machining process to avoid developing a complex closed form formulation for a specific tool wear model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Sensor Data and Information Fusion to Construct Digital-twins Virtual Machine Tools for Cyber-physical Manufacturing
Procedia Manufacturing, 10, 1031–1042.
author keywords: virtual machine tool; sensory data; data acquisition; information fusion; cyber-physical manufacturing; digital manufacturing
TL;DR:
Techniques are discussed for deploying sensors to capture machine-specific features, and analytical techniques of data and information fusion are presented for modeling and developing “digital-twins” virtual machine tools.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Streaming Machine Generated Data to Enable a Third-Party Ecosystem of Digital Manufacturing Apps
Procedia Manufacturing, 10, 1020–1030.
author keywords: Digital Manufacturing; MTCONNECT; PostgreSQL; Digital Manufacturing Commons (DMC)
TL;DR:
This proposed architecture enables an ecosystem of smart manufacturing applications to be built and deployed on the shop-floor through open-sourced software and hardware devices thereby reducing cost of manufacturing software development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Crossref, ORCID
Added: January 25, 2020
2016 journal article
3D-Bioprinting of Polylactic Acid (PLA) Nanofiber–Alginate Hydrogel Bioink Containing Human Adipose-Derived Stem Cells
ACS Biomaterials Science & Engineering, 2(10), 1732–1742.
Contributors: L. Narayanan n, P. Huebner n, M. Fisher n, J. Spang*, n & R. Shirwaiker n
author keywords: bioprinting; knee meniscus; alginate; nanofibers; adipose-derived stem cells; musculoskeletal soft tissue
TL;DR:
This study focuses on the development and proof-of-concept assessment of a fibrous bioink composed of alginate hydrogel, polylactic acid nanofibers, and human adipose-derived stem cells for bioprinting such tissue constructs and shows that the nanofiber-reinforced bioink allowed higher levels of cell proliferation within biopprinted strands.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Fabrication of Lindenmayer System-Based Designed Engineered Scaffolds Using UV-Maskless Photolithography
MRS ADVANCES, 1(11), 749–754.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 conference paper
Modeling human mesenchymal stem cell expansion in vertical wheel bioreactors using lactate production rate in regenerative medicine biomanufacturing
Proceedings of the ASME 11th International Manufacturing Science and Engineering Conference, 2016, vol 2.
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2015 journal article
Alginate Microspheroid Encapsulation and Delivery of MG-63 Cells Into Polycaprolactone Scaffolds: A New Biofabrication Approach for Tissue Engineering Constructs
Journal of Nanotechnology in Engineering and Medicine, 6(2).
Contributors: L. Narayanan n, A. Kumar n, Z. Tan n, S. Bernacki n, n & R. Shirwaiker n
TL;DR:
A new cell delivery approach utilizing deposition of hydrogel-cell encapsulated microspheroids into polycaprolactone (PCL) scaffolds to improve the seeding efficiency is investigated and the role and critical challenges to be addressed are highlighted to successfully utilize 3D-bioprinting for microencapsulated cell delivery.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 6, 2019
2015 journal article
Biofabrication of Multimaterial Three-Dimensional Constructs Embedded With Patterned Alginate Strands Encapsulating PC12 Neural Cell Lines
Journal of Nanotechnology in Engineering and Medicine, 6(2).
TL;DR:
The bioprinting of a three-dimensional (3D) heterogeneous conduit structure encapsulating PC12 neural cells, which was shown to be printed with high cell viability and to proliferate within the rolled construct at a rate consistent with traditional two-dimensional culture.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 15, 2019
2015 journal article
Large scale industrialized cell expansion: producing the critical raw material for biofabrication processes
BIOFABRICATION, 7(4).
author keywords: cell expansion; bioreactors; cellular biomanufacturing; 3D culture
MeSH headings : Bioreactors; Cell Culture Techniques / methods; Cell Proliferation; Tissue Engineering / methods
TL;DR:
Some of the challenges in the field of cellular biomanufacturing that must be addressed are highlighted to achieve desired cellular yields while adhering to the key pillars of good manufacturing practices—safety, purity, stability, potency and identity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Manufacturing Road Map for Tissue Engineering and Regenerative Medicine Technologies
STEM CELLS TRANSLATIONAL MEDICINE, 4(2), 130–135.
Contributors: J. Hunsberger*, O. Harrysson n , R. Shirwaiker n , n , R. Wysk n, P. Cohen n , J. Allickson*, J. Yoo *, A. Atala*
MeSH headings : Biological Specimen Banks; Drug Industry / methods; Drug Industry / organization & administration; Humans; Regenerative Medicine / methods; Regenerative Medicine / organization & administration; Tissue Engineering / methods; Translational Research, Biomedical / methods; Translational Research, Biomedical / organization & administration
TL;DR:
A road map for developing the manufacturing infrastructure, resources, standards, capabilities, education, training, and workforce development to realize the promise of TERM is outlined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
The Influence of MgO Nanoparticles on the Osseointegration of Polycaprolactone - Sodium Alginate Hydrogel Interfaces
British Journal of Applied Science & Technology, 4(1), 79–88.
Ed(s): M. Vimalan
TL;DR:
It is suggested that MgO nanoparticle improves the cell viability of a sodium alginate (SA) hydrogel, but it is detrimental for the osseointegration of PCL-SA hydrogels constructs.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2013 journal article
Controlled release of metronidazole from composite poly-ε-caprolactone/alginate (PCL/alginate) rings for dental implants
Dental Materials, 29(6), 656–665.
author keywords: Localized drug delivery; Dental implants; Poly-epsilon-caprolactone; Alginate; Solvent casting; Metronidazole
MeSH headings : Absorbable Implants; Alginates / chemistry; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / chemistry; Biocompatible Materials / chemistry; Delayed-Action Preparations; Dental Implants; Diffusion; Drug Delivery Systems / instrumentation; Elastic Modulus; Elasticity; Equipment Design; Glucuronic Acid / chemistry; Hexuronic Acids / chemistry; Humans; Hydrogels / chemistry; Metronidazole / administration & dosage; Metronidazole / chemistry; Microbial Sensitivity Tests; Polyesters / chemistry; Stress, Mechanical; Time Factors
TL;DR:
A novel method of controlled localized delivery of antibacterial agents to an implant site using a biodegradable custom fabricated ring and the potential for the ring to inhibit bacterial biofilm growth for the prevention of diseases such as peri-implantitis resulting from bacterial infection at the implant site are demonstrated.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 15, 2019
2011 journal article
A design for the additive manufacture of functionally graded porous structures with tailored mechanical properties for biomedical applications
Journal of Manufacturing Processes, 13(2), 160–170.
TL;DR:
This article discusses a design process for creating periodic cellular structures specifically targeted for biomedical applications and shows the compatibility and matched functional performance characteristics of highly porous parts at a safety factor of 5 and an effective reduction in weight.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 15, 2019
2011 journal article
Alginate based 3D hydrogels as an in vitro co-culture model platform for the toxicity screening of new chemical entities
Toxicology and Applied Pharmacology, 256(1), 62–72.
author keywords: Cell encapsulation; Alginate; 3D culture; HepG2; MCF-7; Co-culture
MeSH headings : Alginates / chemistry; Cell Line, Tumor; Cell Survival / drug effects; Cell Survival / physiology; Cells, Cultured; Coculture Techniques / methods; Drug Evaluation, Preclinical / methods; Drug-Related Side Effects and Adverse Reactions / metabolism; Hep G2 Cells; Humans; Hydrogels / chemistry; Liver / drug effects; Liver / metabolism; Toxicity Tests / methods
TL;DR:
An in vitro 3D co-culture platform provides a scalable and flexible approach to test multiple-cell types in a hybrid setting within standard cell culture plates which may open up novel 3D in vitro culture techniques to screen new chemical entity compounds.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 15, 2019
2011 journal article
Experimental investigation on the operating variables of a near-field electrospinning process via response surface methodology
Journal of Manufacturing Processes, 13(2), 104–112.
Sources: Crossref, ORCID
Added: September 15, 2019
2011 journal article
Sustainment: A Growth Industry for Custom Manufacturing in the United States
Journal of Aviation and Aerospace Perspectives, 1(1), 5–16.
Source: NC State University Libraries
Added: December 24, 2020
2011 journal article
Virtual and Real: Using 3D Scanning, Modeling and Printing in Reconstructing a Juvenile Apatosaurus Skeleton
Journal of Vertebrate Paleontology, 31(Supplement 2).
Source: NC State University Libraries
Added: December 24, 2020
2010 journal article
Long-term cultivation of HepG2 liver cells encapsulated in alginate hydrogels: A study of cell viability, morphology and drug metabolism
Toxicology in Vitro, 24(4), 1314–1323.
author keywords: Cell encapsulation; 3D tissue models; Alginate; Hydrogels; CYP enzymes
MeSH headings : Alginates / ultrastructure; Cell Culture Techniques; Cell Survival / drug effects; Coumarins / metabolism; Cytochrome P-450 Enzyme System / metabolism; Glutathione / metabolism; Hep G2 Cells; Hydrogels; Prodrugs / metabolism; Toxicity Tests / methods
TL;DR:
The results indicate that cells encapsulated within SLM100 and SLG100 class of alginates have shown high cellular viability with >80% even after 14 days in culture, and the proliferation rates of the encapsulated cells are held steady and do not proliferate within the gels.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 15, 2019
2010 journal article
Mechanical evaluation of porous titanium (Ti6Al4V) structures with electron beam melting (EBM)
Journal of the Mechanical Behavior of Biomedical Materials, 3(3), 249–259.
MeSH headings : Alloys; Bone Substitutes / chemistry; Bone and Bones / physiology; Compressive Strength; Electrons; Materials Testing / methods; Microscopy, Electron, Scanning; Porosity; Prostheses and Implants; Surface Properties; Titanium / chemistry; Weight-Bearing; X-Ray Microtomography
TL;DR:
It is found that the porous structures produced by the electron beam melting process present a promising rapid manufacturing process for the direct fabrication of customized titanium implants for enabling personalized medicine.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 15, 2019
2009 journal article
A Lindenmayer system-based approach for the design of nutrient delivery networks in tissue constructs
Biofabrication, 1(4), 045004.
MeSH headings : Algorithms; Animals; Biotechnology; Computer-Aided Design; Humans; Kidney / blood supply; Models, Cardiovascular; Photochemical Processes; Porosity; Rats; Tissue Engineering / methods; Tissue Scaffolds; Ultraviolet Rays
TL;DR:
The Lindenmayer system is presented, an elegant fractal-based language algorithm framework, to generate conduit networks in two- and three-dimensional architecture with several degrees of complexity to demonstrate the applicability of L-system-based construct designs to drive scaffold fabrication systems.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 15, 2019
2009 journal article
Computer Aided Biomodeling and Analysis of Patient Specific Porous Titanium Mandibular Implants
Journal of Medical Devices, 3(3).
author keywords: CT reconstruction mandibular implants; porous titanium layered manufacturing
TL;DR:
A representative volume element based technique in which precisely defined porous implants with customized stiffness values are designed to match the stiffness and weight characteristics of surrounding healthy bone tissue is discussed.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2009 journal article
Real time in vitro measurement of oxygen uptake rates for HEPG2 liver cells encapsulated in alginate matrices
Microfluidics and Nanofluidics, 6(3), 373–381.
author keywords: Oxygen uptake rate (OUR); Fiber optic sensor; Alginate; HEPG2 liver cells
TL;DR:
It is concluded that THE AUTHORS' can be used as an indicative parameter to assess the metabolic activity of cells encapsulated within a matrix and a fiber optic sensing technology as a non-invasive diagnostic tool to monitor cell behavior and activity.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2007 journal article
A tracer metric numerical model for predicting tortuosity factors in three-dimensional porous tissue scaffolds
Computer Methods and Programs in Biomedicine, 87(1), 21–27.
author keywords: three-dimensional tortuosity; porous media; tracer analysis; tissue engineering
MeSH headings : Connective Tissue / physiology; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional / methods; Models, Statistical; Transplants; United States
TL;DR:
The development of a numerical characterization technique to measure the three-dimensional tortuosity factors for any given interconnected porous design will provide a basis for the study of transport properties of the designed scaffold and its effect on cellular function and response through the development of dynamic culture bioreactors.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2007 journal article
Enabling Sensor Technologies for the Quantitative Evaluation of Engineered Tissue
Annals of Biomedical Engineering, 36(1), 30–40.
author keywords: biomedical sensors; tissue engineering; noninvasive monitoring; engineered tissue
MeSH headings : Biological Assay / methods; Biological Assay / trends; Biosensing Techniques / methods; Biosensing Techniques / trends; Biotechnology / methods; Biotechnology / trends; Cell Culture Techniques / methods; Cell Culture Techniques / trends; Equipment Failure Analysis / instrumentation; Equipment Failure Analysis / methods; Tissue Engineering / instrumentation; Tissue Engineering / methods
TL;DR:
The article presents a short description on the core technologies and research reviews on the use of sensors employed in tissue engineering over the past decade and some of the challenges to the further development of these technologies that are capable of real time measurement of tissue structure, composition, and function both for in-vitro and in- vivo analysis.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2007 journal article
Internal Scaffold Architecture Designs using Lindenmayer Systems
Computer-Aided Design and Applications, 4(1-4), 395–403.
Sources: Crossref, ORCID
Added: January 5, 2020
2006 journal article
Application of computer-assisted design in craniofacial reconstructive surgery using a commercial image guidance system
Journal of Neurosurgery: Pediatrics, 104(1), 64–67.
author keywords: craniofacial deformity; craniosynostosis; computer-assisted design; image guidance; neurosurgical simulation; pediatric neurosurgery
MeSH headings : Child; Computer-Aided Design; Craniosynostoses / surgery; Humans; Intraoperative Period; Male; Neurosurgical Procedures / methods; Plastic Surgery Procedures / methods
TL;DR:
The authors report an example of the marriage of computer-assisted design methods to a commercially available neurosurgical image-guidance system in the treatment of a case of anterior plagiocephaly due to unilateral coronal synostosis.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2006 journal article
Computer Aided Tissue Engineering for the Design and Evaluation of Lumbar-Spine Arthroplasty
Computer-Aided Design and Applications, 3(6), 771–778.
TL;DR:
The goal of this study was to develop a scaffold-like intervertebral disc with the mechanical characteristics required to function in the lumbar spine environment, thereby facilitating biological growth and eventual fixation of the disc within the spinal column.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2006 journal article
Internal architecture design and freeform fabrication of tissue replacement structures
Computer-Aided Design, 38(2), 115–124.
author keywords: computer-aided tissue engineering; scaffold design; interior architecture; TheriForm
TL;DR:
The details of the development in the design and fabrication of the interior architecture of scaffolds using a novel design approach that seeks to generate layered scaffold freeform fabrication tool path without forming complicated 3D CAD scaffold models are presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(OpenAlex)
Sources: Crossref, ORCID
Added: January 5, 2020
2005 journal article
A Computer-aided Multi-scale Modeling and Direct Fabrication of Bone Structure
Computer-Aided Design and Applications, 2(5), 627–635.
TL;DR:
It was shown that the reconstructed model is statistically equivalent to the original structure in the microscopic level and the design intension can be integrated in the developed model.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2005 journal article
Bio-CAD modeling and its applications in computer-aided tissue engineering
Computer-Aided Design, 37(11), 1097–1114.
author keywords: CAD Bio-CAD; biomodeling; computer-aided tissue engineering; tissue scaffold design
TL;DR:
Enabling state-of-the-art computer software in assisting 3D reconstruction and in bio-modeling development will be introduced, and utilization of the bio-CAD model for the description and representation of the morphology, heterogeneity, and organizational structure of tissue anatomy, and the generation of bio-blueprint modeling are presented.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2005 journal article
Computer-aided characterization for effective mechanical properties of porous tissue scaffolds
Computer-Aided Design, 37(1), 65–72.
author keywords: computer-aided tissue engineering; tissue engineering; tissue scaffold; freeform fabrication; effective properties
TL;DR:
Application of the algorithm to characterize the effective mechanical properties of porous poly-e-caprolactone scaffold manufactured by precision extruding freeform deposition will also be presented, along with a parametric study of the process and design parameter to the structural properties of tissue scaffold.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2005 journal article
Creation of a unit block library of architectures for use in assembled scaffold engineering
Computer-Aided Design, 37(11), 1141–1149.
author keywords: rapid prototyping; tissue engineering; computer-aided designs; scaffolds; computer-aided tissue engineering (CATE); cellular solids; permeability
TL;DR:
To aid scientists in fabrication of a successful scaffold, characterization and documentation of a library of micro-architectures capable of being seamlessly merged according to the mechanical properties, flow perfusion characteristics, and porosity, determined by the scientist based on application and anatomic location are proposed.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2005 journal article
Direct slicing of STEP based NURBS models for layered manufacturing
Computer-Aided Design, 37(4), 387–397.
author keywords: direct slicing; solid freeform fabrication; layered manufacturing; biomodeling; medical rapid prototyping
TL;DR:
The results of the development of a direct slicing algorithm for layered freeform fabrication based on a neutral, international standard STEP-formatted non-uniform rational B-spline (NURBS) geometric representation and is intended to be independent of any commercial CAD software are presented.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2005 journal article
Three-Dimensional Reconstruction for Medical-CAD Modeling
Computer-Aided Design and Applications, 2(1-4), 431–438.
TL;DR:
Methodology to generate bio-CAD models from high resolution non-invasive imaging, the medical image process and the 3D reconstruction technique will be described, enabling state-of-the-art computer programs to be enabled.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 10, 2020
2004 journal article
Computer Aided Tissue Engineering for Modeling and Design of Novel Tissue Scaffolds
Computer-Aided Design and Applications, 1(1-4), 633–640.
TL;DR:
Some of the salient applications of CATE are presented, particularly in the modeling and design of scaffolds with controlled internal and external architecture; with vascular channels of different sizes; with modular and interconnecting subunits; with multi-layered heterogeneous dense and compact regions.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2004 journal article
Computer-aided tissue engineering: application to biomimetic modelling and design of tissue scaffolds
Biotechnology and Applied Biochemistry, 39(1), 49.
author keywords: bone scaffold; computer-aided design (CAD); computer-aided tissue engineering (CATE); tissue engineering; tissue scaffold design
MeSH headings : Biocompatible Materials / chemical synthesis; Biomechanical Phenomena; Biomimetics / methods; Bone Substitutes; Computer-Aided Design; Membranes, Artificial; Models, Anatomic; Tissue Engineering / methods
TL;DR:
A general CATE‐based process for biomimetic modelling, anatomic reconstruction, computer‐assisted‐design of tissue scaffold, quantitative‐computed‐tomography characterization, finite element analysis and freeform extruding deposition for fabrication of scaffold is presented.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
2004 journal article
Computer-aided tissue engineering: overview, scope and challenges
Biotechnology and Applied Biochemistry, 39(1), 29.
author keywords: cell printing; computer-aided tissue engineering; organ printing; solid freeform fabrication; tissue engineering; tissue scaffold
MeSH headings : Animals; Artificial Organs; Biocompatible Materials / chemical synthesis; Blood Vessels / physiology; Computer-Aided Design; Humans; Micromanipulation; Models, Biological; Tissue Engineering / methods; Tissue Transplantation / methods
TL;DR:
Methodologies of development of CATE modelling from high‐resolution non‐invasive imaging and image‐based three‐dimensional reconstruction, and various reconstructive techniques for CAD‐based tissue modelling generation will be described.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020
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