Brady Zanella
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Works (1)
Updated: April 5th, 2024 17:03
2023 article
Mechanistic Studies of Aziridine Formation Catalyzed by Mononuclear Non-Heme Iron Enzymes
Cha, L., Paris, J. C., Zanella, B., Spletzer, M., Yao, A., Guo, Y., & Chang, W.-chen. (2023, March 13). JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol. 3.
MeSH headings : Iron / chemistry; Aziridines; Hydroxylation; Catalysis
TL;DR:
The use of in silico methods to identify enzymes with potential aziridine-installing (aziridinase) functionality are reported and reconstitute enzymatic activity in vitro and demonstrate that an iron(IV)-oxo species initiates aziridine ring closure by the C-H bond cleavage.
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3. Good Health and Well-being
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Sources: Web Of Science, ORCID
Added: April 4, 2023
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