Brigid Troan

Works (19)

Updated: January 28th, 2026 07:09

2025 journal article

Colloidal-Fibrillar Composite Gels Demonstrate Structural Reinforcement, Secondary Fibrillar Alignment, and Improved Vascular Healing Outcomes

Communications Engineering, 4, 67.

By: N. Moiseiwitsch n, S. Pandit n, N. Zwennes n, K. Nellenbach n, A. Sheridan n, J. LeGrand n, E. Chee n, S. Ozawa n  ...

topics (OpenAlex): Intracranial Aneurysms: Treatment and Complications; Connective tissue disorders research; Bone Tissue Engineering Materials
Sources: Web Of Science, NC State University Libraries, NC State University Libraries
Added: April 12, 2025

2025 article

Immune-cancer analyses across mammals reveal a potential trophic level and platelet-linked tradeoff between cancer and trauma mortality

Kapsetaki, S. E., Seyedi, S., Compton, Z. T., Rupp, S. M., Duke, E. G., Schiffman, J. D., … Boddy, A. M. (2025, December 11). (Vol. 12). Vol. 12.

By: S. Kapsetaki *, S. Seyedi *, Z. Compton *, S. Rupp*, E. Duke  n, J. Schiffman *, B. Troan n, T. Harrison n  ...

topics (OpenAlex): Inflammatory Biomarkers in Disease Prognosis; Immune cells in cancer; Hematopoietic Stem Cell Transplantation
Sources: NC State University Libraries, NC State University Libraries
Added: January 27, 2026

2024 article

Cancer Prevalence across Vertebrates

Compton, Z. T., Mellon, W., Harris, V. K., Rupp, S., Mallo, D., Kapsetaki, S. E., … Boddy, A. M. (2024, October 24). Cancer Discovery, Vol. 15, pp. 227–244.

By: Z. Compton *, W. Mellon, V. Harris, S. Rupp, D. Mallo, S. Kapsetaki, M. Wilmot, R. Kennington ...

MeSH headings : Animals; Neoplasms / epidemiology; Neoplasms / genetics; Neoplasms / veterinary; Prevalence; Vertebrates; Humans
topics (OpenAlex): Veterinary Oncology Research; Molecular Biology Techniques and Applications; Animal Virus Infections Studies
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UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 27, 2025

2024 article

Evaluation of Neoplasia, Treatments, and Survival in Lizard Species

Willig, F., Torpy, F. J., Harrison, S. H., Duke, E. G., Troan, B., Boddy, A. M., … Harrison, T. M. (2024, May 7). Animals, Vol. 14.

By: F. Willig n, F. Torpy n, S. Harrison *, E. Duke  n, B. Troan n, A. Boddy  n, L. Abegglen  n, T. Harrison n 

author keywords: neoplasia; lizard; surgery; chemotherapy; bearded dragon; iguana; monitor; lymphoma; carcinoma
topics (OpenAlex): Turtle Biology and Conservation; Veterinary Oncology Research; Microbial infections and disease research
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 15, 2024

2024 article

Osteosarcoma of the wing in a sulfur‐crested cockatoo

Hastain, S. A., Mumm, L., Ozawa, S., Petritz, O., Gaudette, C., Troan, B. V., & Stowe, D. M. (2024, January 2). Veterinary Clinical Pathology, Vol. 1.

By: S. Hastain n, L. Mumm n, S. Ozawa n , O. Petritz n , C. Gaudette n, B. Troan n, D. Stowe n 

MeSH headings : Humans; Female; Animals; Cockatoos; Osteosarcoma / diagnosis; Osteosarcoma / veterinary; Sarcoma / veterinary; Sulfur; Bone Neoplasms / diagnosis; Bone Neoplasms / veterinary
topics (OpenAlex): Turtle Biology and Conservation; Bird parasitology and diseases; Aquaculture disease management and microbiota
TL;DR: Support is provided for NBT/BCIP application in ALP-expressing tumors, a cytochemical stain that has been minimally investigated in avian species, and its cytologic and histologic features. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 16, 2024

2024 article

Retrospective Study of the Prevalence, Histopathology, Therapy, and Survival Time of Neoplastic Disease in Fish

Ferraro, E., Harrison, S. H., Duke, E., Troan, B., Boddy, A., Abegglen, L. M., & Harrison, T. M. (2024, January 31). Animals, Vol. 14.

By: E. Ferraro n, S. Harrison *, E. Duke  n, B. Troan n, A. Boddy *, L. Abegglen *, T. Harrison n 

author keywords: cancer; neoplasia; fish; shark; sarcoma; carcionoma; zoo; aquarium; pathology; histopathology
topics (OpenAlex): Aquaculture disease management and microbiota; Microbial infections and disease research; Myxozoan Parasites in Aquatic Species
TL;DR: Surgical excision of tumors in fish, when feasible for the patient and client, may improve patient outcomes, demonstrate that while information related to clinical therapy of cancer in fish species is lacking, surgical excision of tumors in fish may improve patient outcomes. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 5, 2024

2024 article

Testing Adaptive Therapy Protocols Using Gemcitabine and Capecitabine in a Preclinical Model of Endocrine-Resistant Breast Cancer

Seyedi, S., Teo, R., Foster, L., Saha, D., Mina, L., Northfelt, D., … Maley, C. C. (2024, January 6). Cancers.

By: S. Seyedi *, R. Teo*, L. Foster *, D. Saha *, L. Mina *, D. Northfelt *, K. Anderson *, D. Shibata * ...

author keywords: adaptive therapy; endocrine-resistant MCF7 breast cancer; high-dose therapy; drug-resistant and drug-sensitive subclones
topics (OpenAlex): Cancer Treatment and Pharmacology; Cancer Genomics and Diagnostics; Advanced Breast Cancer Therapies
TL;DR: Adaptive therapy aims to overcome resistance and reduce toxicity by leveraging competitive interactions between drug-sensitive and drug-resistant subclones, prioritizing patient survival and quality of life instead of killing the maximum number of cancer cells. (via Semantic Scholar)
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Source: Web Of Science
Added: February 12, 2024

2023 article

Investigation of Potassium Chloride for Euthanasia of Anesthetized African Clawed Frogs (Xenopus laevis)

Olagbaju, T. T., Troan, B. V., & Balko, J. A. (2023, June 13). Journal of the American Association for Laboratory Animal Science.

By: T. Olagbaju n, B. Troan n & J. Balko n

MeSH headings : Female; Animals; Potassium Chloride; Xenopus laevis; Ice; Euthanasia, Animal / methods; Potassium
topics (OpenAlex): Animal testing and alternatives; Amphibian and Reptile Biology; Immunotoxicology and immune responses
TL;DR: Return to MS-222 solution after KCl administration may be warranted to prevent unintended, premature anesthetic recovery prior to death of anesthetized African clawed frogs. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: November 27, 2023

2023 article

Retrospective analysis of histologic lesions in captive arachnids

Gaudette, C., LaDouceur, E. E. B., Troan, B. V., Whitehurst, N., Dombrowski, D. S., Lewbart, G. A., … Schreeg, M. E. (2023, April 10). Veterinary Pathology, Vol. 4.

By: C. Gaudette n, E. LaDouceur, B. Troan n, N. Whitehurst n, D. Dombrowski*, G. Lewbart n , K. Linder n, K. Passingham n, L. Christian*, M. Schreeg n

author keywords: Araneae; arthropod; Heterometrus; histopathology; inflammation; invertebrate; scorpion; Scorpiones; tarantula
topics (OpenAlex): Invertebrate Immune Response Mechanisms; Vector-Borne Animal Diseases; Neurobiology and Insect Physiology Research
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UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 1, 2023

2023 article

Sudden death in a 5-year-old female African pancake tortoise (Malacocherusus tornieri)

Watanabe, T. T. N., Murillo, D. F. B., White, A., Talley, A., Minter, L. J., & Troan, B. V. (2023, September 27). Journal of the American Veterinary Medical Association.

By: T. Watanabe  n, D. Murillo *, A. White n, A. Talley*, L. Minter* & B. Troan n

author keywords: Entamoeba invadens; African pancake tortoise; Malacocherusus tornieri; amoebiasis; hepatitis
MeSH headings : Female; Animals; Turtles; Death, Sudden / veterinary; Entamoeba
topics (OpenAlex): Turtle Biology and Conservation; Identification and Quantification in Food; Animal Diversity and Health Studies
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Source: Web Of Science
Added: February 19, 2024

2023 article

Vitamin A, Vitamin E, and Carotenoid Concentrations in Livers of Marine Toads (Rhinella marina)

Lee, H., Minter, L. J., Tollefson, T. N., Ridgley, F., Smith, D., Treiber, K., … Heugten, K. D. A.-van. (2023, February 8). Journal of Zoological and Botanical Gardens, Vol. 4, pp. 134–145.

By: H. Lee  n, L. Minter n, T. Tollefson, F. Ridgley *, D. Smith *, K. Treiber*, H. Scott*, B. Troan n, K. Heugten n 

author keywords: amphibians; fat soluble vitamins; nutrition; carotenoids
topics (OpenAlex): Insect Utilization and Effects; Animal and Plant Science Education
TL;DR: The results from this study indicate that higher dietary vitamin A, vitamin E, and carotenoid content may be needed and/or the cricket gut loading and dusting techniques used to feed the amphibians food source insects may be inadequate. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 10, 2023

2022 article

A Multi-Institutional Collaboration to Understand Neoplasia, Treatment and Survival of Snakes

Duke, E. G., Harrison, S. H., Moresco, A., Trout, T., Troan, B. V., Garner, M. M., … Harrison, T. M. (2022, January 21). Animals, Vol. 2, p. 258.

By: E. Duke n, S. Harrison *, A. Moresco n , T. Trout*, B. Troan n, M. Garner, M. Smith  n, S. Smith n, T. Harrison n 

author keywords: Boidae; chemotherapy; Colubridae; neoplasia; oncology; surgery; prevalence; Viperida
topics (OpenAlex): Turtle Biology and Conservation; Microbial infections and disease research; Veterinary Oncology Research
TL;DR: The prevalence of tumors in 133 snakes, representing 65 different species, housed in six zoos and aquariums was calculated to provide data on a select population of snakes to help veterinarians gain greater understanding of cancer types and to treat cancer in these animals. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 26, 2022

2022 article

Of Elephants and Other Mammals: A Comparative Review of Reproductive Tumors and Potential Impact on Conservation

Abegglen, L. M., Harrison, T. M., Moresco, A., Fowles, J. S., Troan, B. V., Kiso, W. K., … Schiffman, J. D. (2022, August 8). Animals.

By: L. Abegglen  n, T. Harrison n , A. Moresco n , J. Fowles *, B. Troan n, W. Kiso, D. Schmitt *, A. Boddy  n, J. Schiffman  n

Contributors: L. Abegglen  n, T. Harrison n , A. Moresco n , J. Fowles *, B. Troan n, W. Kiso, D. Schmitt *, A. Boddy  n, J. Schiffman  n

author keywords: Elephas maximus; Loxodonta africana; fertility; leiomyoma; neoplasia; prevention; treatment; uterine; fibroid; comparative oncology
topics (OpenAlex): Reproductive Biology and Fertility; Reproductive Physiology in Livestock; Wildlife Ecology and Conservation
TL;DR: Evidence suggests that reproductive tumors can negatively impact elephant conservation, and future studies that document reproductive outcomes, including the success of various treatment approaches in elephants with tumors will benefit conservation efforts. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 13, 2022

2022 article

Retrospective Analysis of Cataract Formation and Nutritional Etiology in a Managed Collection of Parakeet Auklets (Aethia psittacula)

Phillips, B. E., Dierenfeld, E. S., English, R., Troan, B., Reininger, K., Zombeck, D. J., … Minter, L. J. (2022, January 28). Journal of Avian Medicine and Surgery.

By: B. Phillips*, E. Dierenfeld, R. English, B. Troan*, K. Reininger*, D. Zombeck*, R. DeVoe*, B. Wolfe*, M. Loomis n, L. Minter n

MeSH headings : Animals; Birds; Cataract / etiology; Cataract / veterinary; Charadriiformes; Retrospective Studies
topics (OpenAlex): Connexins and lens biology; Heme Oxygenase-1 and Carbon Monoxide; Animal Ecology and Behavior Studies
TL;DR: The parakeet auklet is a piscivorous seabird with a natural diet of various invertebrate and teleost species, which is challenging to replicate in a managed collection, which was hypothesized to be related to inappropriate vitamin A and E levels. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: February 21, 2022

2021 article

Ductal Plate Malformations in Captive Snakes

Patania, O. M., Troan, B. V., & Cullen, J. M. (2021, May 3). Veterinary Pathology.

By: O. Patania  n, B. Troan n & J. Cullen n

author keywords: bile ducts; ductal plate malformation; immunohistochemistry; liver; polycystic liver disease; snake; von Meyenburg complex
MeSH headings : Animals; Bile Ducts; Bile Ducts, Intrahepatic; Cysts / veterinary; Liver Diseases / veterinary; Snakes
topics (OpenAlex): Pediatric Hepatobiliary Diseases and Treatments; Genetic and Kidney Cyst Diseases; Congenital Anomalies and Fetal Surgery
TL;DR: Histochemical and immunohistochemical staining, including Gomori’s trichome and pan-cytokeratin, respectively, were applied on select cases to confirm histologic features of ductal plate malformations in captive snakes. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: June 14, 2021

2021 journal article

Migration and Histologic Effects of Visible Implant Elastomer (VIE) and Passive Integrated Transponder (PIT) Tags in the Marine Toad (Rhinella marina)

Animals, 11(11), 3255.

By: M. Cabot n, B. Troan n, K. Ange-van Heugten n , R. Schnellbacher *, D. Smith *, F. Ridgley *, L. Minter n

author keywords: marine toad; passive integrated transponder (PIT); pathology; Rhinella marina; visible implant elastomer (VIE)
topics (OpenAlex): Turtle Biology and Conservation; Amphibian and Reptile Biology; Bird parasitology and diseases
TL;DR: Evaluated for pathologic changes associated with passive integrated transponder (PIT) and visible implant elastomer (VIE) tags in the marine toad (Rhinella marina), it is recommended that the use of PIT tags over VIE tags for identification of adult anurans, when feasible, is recommended. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: February 17, 2022

2020 article

Taxonomic Distribution of Neoplasia among Non-Domestic Felid Species under Managed Care

Moresco, A., Muñoz, K., Gutiérrez, F., Arias-Bernal, L., Yarto-Jaramillo, E., Teixeira, R., … Troan, B. (2020, December 11). Animals, Vol. 10, p. 2376.

By: A. Moresco n , K. Muñoz, F. Gutiérrez, L. Arias-Bernal *, E. Yarto-Jaramillo *, R. Teixeira *, J. Peña-Stadlin, B. Troan n

Contributors: A. Moresco n , K. Munoz, F. Gutierrez, L. Arias-Bernal *, E. Yarto-Jaramillo *, R. Teixeira *, J. Pena-Stadlin, B. Troan n

author keywords: cancer; jaguar; mammary carcinoma; Leopardus; Otocolobus; Panthera; Puma; Neofelis; seminoma; Sertoli cell tumor
topics (OpenAlex): Veterinary Oncology Research; Microbial infections and disease research; Virus-based gene therapy research
TL;DR: It is found that jaguars, lions, tigers and leopards are at a much higher risk of developing cancer than small cats and routine medical exams in all nondomestic felids, but Panthera species in particular, should include thorough assessments of any clinical signs of neoplasia. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 19, 2021

2016 article

Amoebic meningoencephalitis and disseminated infection caused by Balamuthia mandrillaris in a Western lowland gorilla (Gorilla gorilla gorilla)

Gjeltema, J. L., Troan, B., Muehlenbachs, A., Liu, L., Silva, A. J. D., Qvarnstrom, Y., … Voe, R. S. D. (2016, January 22). Journal of the American Veterinary Medical Association.

By: J. Gjeltema*, B. Troan*, A. Muehlenbachs, L. Liu, A. Silva, Y. Qvarnstrom, J. Tobias*, M. Loomis*, R. Voe*

MeSH headings : Amebiasis / parasitology; Amebiasis / veterinary; Animals; Ape Diseases / parasitology; Balamuthia mandrillaris / isolation & purification; Balamuthia mandrillaris / pathogenicity; Central Nervous System Protozoal Infections / parasitology; Central Nervous System Protozoal Infections / veterinary; Gorilla gorilla / parasitology; Male; Periodontal Abscess / complications; Periodontal Abscess / parasitology; Periodontal Abscess / veterinary; Tooth Root / parasitology; Tooth Root / pathology
topics (OpenAlex): Legionella and Acanthamoeba research; Cerebrospinal fluid and hydrocephalus; Rabies epidemiology and control
TL;DR: A 22-year-old male gorilla housed in a zoo was evaluated for signs of lethargy, head-holding, and cervical stiffness followed by development of neurologic abnormalities including signs of depression, lip droop, and tremors, and was diagnosed with amoebic meningoencephalitis. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2014 article

Malignant hypertension and retinopathy in a western lowland gorilla (Gorilla gorilla gorilla)

Niemuth, J. N., Voe, R. S. D., Jennings, S. H., Loomis, M. R., & Troan, B. V. (2014, March 20). Journal of Medical Primatology, Vol. 43, pp. 276–279.

By: J. Niemuth n , R. Voe n, S. Jennings n, M. Loomis n & B. Troan n

author keywords: arteriosclerosis; hypertensive encephalopathy; necrotizing arteriolitis; retinal detachment
MeSH headings : Animals; Animals, Zoo; Eye / pathology; Female; Gorilla gorilla; Hypertension, Malignant / pathology; Hypertension, Malignant / veterinary; Hypertensive Retinopathy / pathology; Hypertensive Retinopathy / veterinary
topics (OpenAlex): Cerebral Venous Sinus Thrombosis; Neurological Complications and Syndromes; Pituitary Gland Disorders and Treatments
TL;DR: A 34‐year‐old western lowland gorilla presented with peracute blindness and died at the age of 34 after suffering from multiple organ failure. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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