@article{thulson_davis_d'costa_coryell_kramer_mohlke_loeser_diekman_phanstiel_2022, title={3D chromatin structure in chondrocytes identifies putative osteoarthritis risk genes}, ISSN={["1943-2631"]}, DOI={10.1093/genetics/iyac141}, journal={GENETICS}, author={Thulson, Eliza and Davis, Eric S. and D'Costa, Susan and Coryell, Philip R. and Kramer, Nicole E. and Mohlke, Karen L. and Loeser, Richard F. and Diekman, Brian O. and Phanstiel, Douglas H.}, year={2022}, month={Sep} } @article{copp_chubinskaya_bracey_shine_sessions_loeser_diekman_2022, title={Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis}, ISSN={["1474-9726"]}, DOI={10.1111/acel.13698}, journal={AGING CELL}, author={Copp, Michaela E. and Chubinskaya, Susan and Bracey, Daniel N. and Shine, Jacqueline and Sessions, Garrett and Loeser, Richard F. and Diekman, Brian O.}, year={2022}, month={Aug} } @article{novais_tran_johnston_darris_roupas_sessions_shapiro_diekman_risbud_2021, title={Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice}, volume={12}, ISSN={["2041-1723"]}, DOI={10.1038/s41467-021-25453-2}, number={1}, journal={NATURE COMMUNICATIONS}, author={Novais, Emanuel J. and Tran, Victoria A. and Johnston, Shira N. and Darris, Kayla R. and Roupas, Alex J. and Sessions, Garrett A. and Shapiro, Irving M. and Diekman, Brian O. and Risbud, Makarand V}, year={2021}, month={Sep} } @article{collins_kapustina_bolduc_pike_diekman_mix_chubinskaya_eroglu_michel_poole_et al._2021, title={Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes}, volume={166}, ISBN={1873-4596}, DOI={10.1016/j.freeradbiomed.2021.01.054}, journal={FREE RADICAL BIOLOGY AND MEDICINE}, author={Collins, John A. and Kapustina, Maryna and Bolduc, Jesalyn A. and Pike, James F. W. and Diekman, Brian O. and Mix, Kimberlee and Chubinskaya, Susan and Eroglu, Emrah and Michel, Thomas and Poole, Leslie B. and et al.}, year={2021}, month={Apr}, pages={90–103} } @article{copp_flanders_gagliardi_gilbertie_sessions_chubinskaya_loeser_schnabel_diekman_2021, title={The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence}, volume={29}, ISBN={1522-9653}, DOI={10.1016/j.joca.2020.11.004}, number={3}, journal={OSTEOARTHRITIS AND CARTILAGE}, author={Copp, M. E. and Flanders, M. C. and Gagliardi, R. and Gilbertie, J. M. and Sessions, G. A. and Chubinskaya, S. and Loeser, R. F. and Schnabel, L. and Diekman, B. O.}, year={2021}, month={Mar}, pages={402–412} } @article{tessier_doolittle_sao_rotty_bear_ulici_loeser_shapiro_diekman_risbud_2020, title={Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation}, volume={5}, ISBN={2379-3708}, DOI={10.1172/jci.insight.131382}, number={4}, journal={JCI INSIGHT}, author={Tessier, Steven and Doolittle, Alexandra C. and Sao, Kimheak and Rotty, Jeremy D. and Bear, James E. and Ulici, Veronica and Loeser, Richard F. and Shapiro, Irving M. and Diekman, Brian O. and Risbud, Makarand V}, year={2020} } @article{loeser_kelley_armstrong_collins_diekman_carlson_2020, title={Deletion ofJNKEnhances Senescence in Joint Tissues and Increases the Severity of Age-Related Osteoarthritis in Mice}, volume={72}, ISBN={2326-5205}, DOI={10.1002/art.41312}, number={10}, journal={ARTHRITIS & RHEUMATOLOGY}, author={Loeser, Richard F. and Kelley, Kathryn L. and Armstrong, Alexandra and Collins, John A. and Diekman, Brian O. and Carlson, Cathy S.}, year={2020}, pages={1679–1688} } @article{diekman_2020, title={Dynamic interplay between connective tissues and the surrounding environment during aging}, volume={61}, ISBN={1607-8438}, DOI={10.1080/03008207.2020.1682282}, number={1}, journal={CONNECTIVE TISSUE RESEARCH}, author={Diekman, Brian O'Callaghan}, year={2020}, pages={1–3} } @article{griffith_huang_cho_khare_rich_lee_ligler_diekman_polacheck_2020, title={Microfluidics for the study of mechanotransduction}, volume={53}, ISBN={1361-6463}, DOI={10.1088/1361-6463/ab78d4}, number={22}, journal={JOURNAL OF PHYSICS D-APPLIED PHYSICS}, author={Griffith, Christian M. and Huang, Stephanie A. and Cho, Crescentia and Khare, Tanmay M. and Rich, Matthew and Lee, Gi-hun and Ligler, Frances S. and Diekman, Brian O. and Polacheck, William J.}, year={2020} } @article{loeser_collins_diekman_carlson_2020, title={Reply}, ISBN={2326-5205}, DOI={10.1002/art.41431}, journal={ARTHRITIS & RHEUMATOLOGY}, author={Loeser, Richard F. and Collins, John A. and Diekman, Brian O. and Carlson, Cathy S.}, year={2020} } @article{liu_souroullas_diekman_krishnamurthy_hall_sorrentino_parker_sessions_gudkov_sharpless_2019, title={Cells exhibiting strong p16(INK4a) promoter activation in vivo display features of senescence}, volume={116}, DOI={10.1073/pnas.1818313116}, number={7}, journal={PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA}, author={Liu, Jie-Yu and Souroullas, George P. and Diekman, Brian O. and Krishnamurthy, Janakiraman and Hall, Brandon M. and Sorrentino, Jessica A. and Parker, Joel S. and Sessions, Garrett A. and Gudkov, Andrei V. and Sharpless, Norman E.}, year={2019}, pages={2603–2611} } @article{d'costa_rich_diekman_2019, title={Engineered Cartilage from Human Chondrocytes with Homozygous Knockout of Cell Cycle Inhibitor p21}, ISBN={1937-335X}, DOI={10.1089/ten.tea.2019.0214}, journal={TISSUE ENGINEERING PART A}, author={D'Costa, Susan and Rich, Matthew J. and Diekman, Brian O.}, year={2019} } @article{novais_diekman_shapiro_risbud_2019, title={p16(Ink4a) deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence}, volume={82}, ISBN={1569-1802}, DOI={10.1016/j.matbio.2019.02.004}, journal={MATRIX BIOLOGY}, author={Novais, Emanuel J. and Diekman, Brian O. and Shapiro, Irving M. and Risbud, Makarand V.}, year={2019}, month={Sep}, pages={54–70} } @misc{colins_diekman_loeser_2018, title={Targeting aging for disease modification in osteoarthritis}, volume={30}, DOI={10.1097/bor.0000000000000456}, number={1}, journal={Current Opinion in Rheumatology}, author={Colins, J. A. and Diekman, B. O. and Loeser, R. F.}, year={2018}, pages={101–107} }