Christopher Anthony Basciano

Works (5)

Updated: July 7th, 2023 21:15

2010 journal article

COMPUTER MODELING OF YTTRIUM-90-MICROSPHERE TRANSPORT IN THE HEPATIC ARTERIAL TREE TO IMPROVE CLINICAL OUTCOMES

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 76(2), 631–637.

By: A. Kennedy n, C. Kleinstreuer n, C. Basciano n & W. Dezarn*

author keywords: Hepatic artery system; Y-90-microspheres; Computer modeling; Blood flow; Particle transport
MeSH headings : Computer Simulation; Embolization, Therapeutic / methods; Hepatic Artery / anatomy & histology; Hepatic Artery / physiology; Humans; Liver / blood supply; Liver Circulation / physiology; Liver Neoplasms / blood supply; Liver Neoplasms / radiotherapy; Microspheres; Models, Cardiovascular; Yttrium Radioisotopes / pharmacokinetics; Yttrium Radioisotopes / therapeutic use
TL;DR: Computer simulations of both blood flow patterns and microsphere dynamics have the potential to provide valuable insight on how to optimize (90)Y-microsphere implantation into hepatic tumors while sparing normal tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Computer Modeling of Controlled Microsphere Release and Targeting in a Representative Hepatic Artery System

ANNALS OF BIOMEDICAL ENGINEERING, 38(5), 1862–1879.

By: C. Basciano n, C. Kleinstreuer n, A. Kennedy *, W. Dezarn* & E. Childress n

author keywords: Computational fluid-particle dynamics; Yttrium-90 particle transport; Transient particle-hemodynamics; Non-Newtonian fluid; Drug-targeting methodology
MeSH headings : Animals; Computer Simulation; Drug Delivery Systems / methods; Hemodynamics / physiology; Hepatic Artery / physiology; Liver / blood supply; Liver Neoplasms / drug therapy; Liver Neoplasms / radiotherapy; Microspheres; Yttrium / adverse effects
TL;DR: Results begin paving the way towards directing 100% of the released microspheres to specific daughter vessels under transient flow conditions in realistic geometries via a novel drug-particle targeting methodology. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Invariant-Based Anisotropic Constitutive Models of the Healthy and Aneurysmal Abdominal Aortic Wall

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 131(2).

By: C. Basciano n & C. Kleinstreuer n

author keywords: ab initio calculations; biomechanics; blood vessels; diseases; elasticity; physiological models
MeSH headings : Anisotropy; Aorta, Abdominal / physiology; Aortic Aneurysm, Abdominal / physiopathology; Biomechanical Phenomena; Computer Simulation; Elasticity; Humans; Models, Cardiovascular; Nonlinear Dynamics
TL;DR: Although the traditional invariant framework exhibits significant covariance, the invariant terms utilized in the new models exhibited limited covariance and are able to accurately reproduce experimental trends, suggesting numerical stability and potentially the inherent limitations of a covariant theoretical framework. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Computational mechanics of Nitinol stent grafts

JOURNAL OF BIOMECHANICS, 41(11), 2370–2378.

By: C. Kleinstreuer n, Z. Li*, C. Basciano n, S. Seelecke n & M. Farber n

author keywords: stent; stent graft; abdominal aortic aneurysm; Nitinol; graft material; finite element analysis; computer simulations; wall stress and strain; crimp; fatigue; fracture
MeSH headings : Alloys; Computer Simulation; Models, Biological; Stents; Stress, Mechanical
TL;DR: A Nitinol stent with PET graft may greatly improve fatigue life, while its compliance is much lower than the NITI-ePTFE combination, which is not acceptable for proper AAA stent-graft design. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Fluid dynamics of cell cytokinesis - Numerical analysis of intracellular flow during cell division

INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER, 34(1), 1–7.

By: F. Zheng n, C. Basciano n, J. Li n & A. Kuznetsov

author keywords: intracellular flow; cell division; cytokinesis; numerical modeling
TL;DR: Intracellular flow of cytoplasmic fluid during cell cytokinesis is investigated and it is established that the pressure difference between the daughter cell and the intercellular bridge increases as time progresses and a region of stagnation develops on the downstream side of the nucleus as the bridge thins. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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