Characterization of Md5-BAC-REV-LTR virus as Marek's disease vaccine in commercial meat-type chickens: protection and immunosuppression
Ellington, C., Cortes, A. L., Faiz, N. M., Mays, J. K., Fadly, A., Silva, R. F., & Gimeno, I. M. (2021, October 9). AVIAN PATHOLOGY, Vol. 10.
author keywords: Marek's disease; vaccination; immunosuppression; LTR; recombinant vaccines; control
MeSH headings : Animals; Chickens; Herpesvirus 2, Gallid; Immunosuppression Therapy / veterinary; Marek Disease Vaccines / genetics; Meat; Reticuloendotheliosis virus; Terminal Repeat Sequences / genetics
TL;DR:
It is shown that Md5-BAC-REV-LTR has the potential to be used as a MD vaccine and is highly protective against early challenge with vv+ MDV in commercial meat-type chickens.
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