2021 journal article

Synthesis of sonicated fibrin nanoparticles that modulate fibrin clot polymerization and enhance angiogenic responses

Colloids and Surfaces B: Biointerfaces, 204, 111805.

By: C. Roosa n, I. Muhamed n, A. Young n, K. Nellenbach n, M. Daniele n, F. Ligler n, A. Brown n

author keywords: Fibrin; Nanoparticles; Wound healing; Regenerative medicine; Fibrin sealant
MeSH headings : Fibrin; Fibrin Tissue Adhesive; Nanoparticles; Polymerization; Wound Healing
TL;DR: It is shown that SFBNs may be a promising wound healing therapy that can be easily produced and delivered in a flowable formulation and support cell migration in an in vitro angiogenic sprouting assay, relevant for wound healing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: July 19, 2021

2018 journal article

Biomimetic Microgels with Controllable Deformability Improve Healing Outcomes

Advanced Biosystems, 2(10).

By: E. Sproul n, S. Nandi n, C. Roosa n, L. Schreck* & A. Brown n

author keywords: biomimetic; fibrin; microgel; synthetic platelet; wound healing
TL;DR: Hollow PLPs with low degrees of shell crosslinking improve some wound healing outcomes in vivo, recapitulating the clot retraction function of platelets, while other particle types do not. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: October 29, 2018

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