Carlos Christopher Goller
Also known as: Carlos Goller
high-throughput approaches, molecular biology, microbiology, molecular biology education, metagenomics, open educational resources, open educational practices, Delftia
I was born in Mexico and grew up in the city of San Miguel de Allende, Guanajuato. My father was a retired US NAVY Lt. Cdr., and my mother is a retired elementary school teacher who taught for forty years. I attended a bilingual elementary school and then a technical high school in Queretaro (ITESM Campus Queretaro). Thanks to a high school biology teacher named Gabriela Corral, I learned about biotechnology. I was captivated by viruses and bacteria and determined to study biotechnology as a major. Despite my poor guidance counselor trying to convince me to major in physics with a full scholarship at the ITESM, I took a bus several times to Mexico City to take the SAT & SAT subject tests and went to the Benjamin Franklin Library to read about college applications. I applied to several colleges & universities in the United States and attended Worcester Polytechnic Institute in Worcester, MA where I majored in Biology and Biotechnology (yes!). Dr. Jeff Tyler provided a wonderful experience and acted as a superb mentor. I learned about population-based modeling and coding. With Dr. Jose Arguello, I cloned my first bacterial gene. These two undergraduate research experiences convinced me I wanted to pursue a Ph.D. in microbial genetics. My interest in public health and... viruses took me to Emory (next to the CDC) in Atlanta. I was fortunate to join the lab of Dr. Tony Romeo, an incredible bacterial geneticist. I was also lucky to stumble upon Dr. Pat Marsteller and Dr. Arri Eisen who taught me about the joy of reformed teaching and science and society. At Duke, Dr. Pat Seed (the first author of a study I had presented as a journal club topic during graduate school) taught me about the thrill of high-throughput discovery. I was then able to combine teaching and research at North Carolina State University.
Works (124)
Updated: April 22nd, 2024 07:45
2024 journal article
Scaling the wall: overcoming barriers to STEM knowledge mobilization
FRONTIERS IN COMMUNICATION, 9.
author keywords: broader impacts; societal benefits; teacher-researcher collaboration; formal outreach; K-12 education; curriculum development
www.frontiersin.org (publisher PDF)
Sources: Web Of Science, ORCID
Added: April 15, 2024
2023 article
Connecting Ethical Reasoning to Global Challenges through Analysis of Argumentation
Sjogren, C. A., Comstock, G., & Goller, C. C. (2023, March 16). (J. Shaffer, Ed.). JOURNAL OF MICROBIOLOGY & BIOLOGY EDUCATION, Vol. 3.
Contributors: C. Sjogren n, G. Comstock n & n
Ed(s): J. Shaffer
author keywords: critical thinking; argumentation; ethical reasoning; case studies; discussion; literacy; collaborative learning; mastery learning; communicate
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science
Added: March 17, 2023
2023 article
Encontrando Soluciones en su Fregadero (Versión en Español del Video de Carlos Goller)
Goller, C. (2023, August 4).
Source: ORCID
Added: August 11, 2023
2023 article
Finding Health Solutions In Your Sink
Goller, C. (2023, August 4).
Source: ORCID
Added: August 11, 2023
2023 article
Innovating Life Sciences Laboratory Training: Molecular Biology Laboratory Education Modules (MBLEMs) as a Model for Advanced Training at Diverse Institutions
JOURNAL OF BIOLOGICAL CHEMISTRY, Vol. 299, pp. S260–S260.
Sources: Web Of Science, ORCID
Added: September 11, 2023
2023 journal article
Reimaging Leadership in Open Education: Networking to Promote Social Justice and Systemic Change
Journal of Open Educational Resources in Higher Education.
Source: ORCID
Added: February 2, 2024
2022 conference paper
Developing Interdisciplinary and Inclusive Experiences Beyond the Classroom by Starting with a New CURE
Poster presented at the North Carolina Project Kaleidoscope (PKAL NC).
Event: North Carolina Project Kaleidoscope (PKAL NC)
Source: NC State University Libraries
Added: May 21, 2022
2022 journal article
Does organelle shape matter?: Exploring patterns in cell shape and structure with high-throughput (HT) imaging
[Lesson]. CourseSource.
TL;DR:
This lesson demonstrates how the use of high-throughput microscopy has generated data describing organelle structure and variability as well as recommending recommendations and proposing a future experiment.
(via Semantic Scholar)
Sources: NC State University Libraries, ORCID
Added: June 6, 2022
2022 conference paper
Evaluating How Learners Navigate Bioinformatics Narratives and Workflows
Presented at the Lilly Conference Online.
Event: Lilly Conference Online
Source: NC State University Libraries
Added: May 21, 2022
2022 journal article
Hands-on immunology: Engaging learners of all ages through tactile teaching tools
FRONTIERS IN MICROBIOLOGY, 13.
Contributors: M. Ramirez n
author keywords: tactile teaching tool-guided inquiry learning; antibody; epitope; MHC; haplotype; universal design for learning; inclusive teaching; active learning
TL;DR:
Two TTT-GIL activities are reported here designed to engage diverse learners from middle schoolers to masters students in exploring molecular interactions within the immune system and can be adapted for use with learners of different levels and educational backgrounds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
4. Quality Education
(Web of Science)
Sources: Web Of Science, ORCID
Added: October 25, 2022
2022 speech
Learning Outcomes for CURE's, Assessments for Research-based Courses/Evidence of Student Learning. What are they/we learning?
Presented at the NC State Inclusive Excellence HHMI Summer 2022 Workshop, Raleigh, NC.
Event: NC State Inclusive Excellence HHMI Summer 2022 Workshop at Raleigh, NC on May 12, 2022
Source: NC State University Libraries
Added: May 21, 2022
2022 article
Opportunities and Challenges of Online Instruction and Effective Pedagogy That Blurs the Lines between Online and On-Site Teaching and Learning
Pike, A., Pandey, S., Goller, C. C., Herzog, J., & Parks, S. T. (2022, April 11). JOURNAL OF MICROBIOLOGY & BIOLOGY EDUCATION, Vol. 4.
author keywords: editorial; effective pedagogy; online instruction; themed issue
TL;DR:
The 2022 themed issue, “Opportunities and Challenges of Online Instruction: Blurring the Lines Between Online and On-Site Teaching and Learning,” focuses on key topics that are most pertinent to online education, the wealth of practices used to facilitate such an approach to teaching, and how these methods can continue to be used as effective pedagogical tools as the authors strive to improve both remote instruction and the return to in-person teaching.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science
Added: April 14, 2022
2022 conference paper
Se Hace Camino al Anda
Keynote presented at the NC State Latin American Student Association Conference, Raleigh, NC.
Event: NC State Latin American Student Association Conference at Raleigh, NC
Source: NC State University Libraries
Added: May 21, 2022
2022 speech
Social Annotation with Hypothes.is
Virtual workshop presented at the C2 Summit for Pedagogical Advances in STEM, Raritan Valley Community College.
Event: C2 Summit for Pedagogical Advances in STEM at Raritan Valley Community College
Source: NC State University Libraries
Added: May 21, 2022
2022 article
Some Like it Hot!
Goller, C. (2022, January 15). (Vol. 1). Vol. 1.
UN Sustainable Development Goal Categories
13. Climate Action
(OpenAlex)
Source: ORCID
Added: March 6, 2022
2022 speech
The Virtual Science Lab: Does Organelle Shape Matter?
Goller, C. C., Casimo, K., & Metzler, K. (2022, April). Presented at the Allen Institute Webinar.
Event: Allen Institute Webinar on April 26, 2022
Source: NC State University Libraries
Added: May 21, 2022
2022 article
¡Algunos Prefieren lo Caliente! La Vida en Medio Ambiente Extremo
Goller, C. (2022, January 15). (Vol. 1). Vol. 1.
UN Sustainable Development Goal Categories
13. Climate Action
(OpenAlex)
Source: ORCID
Added: March 6, 2022
2021 journal article
Bioinformatic Teaching Resources - For Educators, by Educators - Using KBase, a Free, User-Friendly, Open Source Platform
FRONTIERS IN EDUCATION, 6.
author keywords: computational biology; bioinformatics; data science; STEM education and learning; undergraduate education
TL;DR:
The utility of KBase as a platform for bioinformatics education is demonstrated, and a set of modular, adaptable, and customizable instructional units for teaching concepts in Genomics, Metagenomics, Pangenomics, and Phylogenetics are presented.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: November 23, 2021
2021 conference paper
Building the Open Education Profession with Regional Leadership
Goller, C., Frank, E., Zenon, E., Powell, R., & Cangialosi, K. (2021, July 14). Presented at the Open Education Southern Symposium (OESS).
Event: Open Education Southern Symposium (OESS) on July 14, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Combining open pedagogy and citizen science to empower learners and educators
Tully, D., Cross, W., McKenney, E., & Goller, C. (2021, April 21). Presented at the OERxDomains21 conference.
Event: OERxDomains21 conference on April 21, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 speech
Connecting Courses through a Unique Microbe
Presented at the OERCamp 2021.
Event: OERCamp 2021 on December 10, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 journal article
Divide and Conquer: A Simple Modern Technique for Collaborative Small Group Learning with Reciprocal Peer Teaching
Journal of Microbiology and Biology Education, 22(1), ev22i1-2153.
TL;DR:
Divide and Conquer is a simple, easy-to-use, and modern technique that faculty and instructors can use to rapidly transform traditional lecture content into collaborative small group learning and peer-teaching experiences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, ORCID
Added: June 21, 2021
2021 article
Editorial: Research Topic Tools, Techniques, and Strategies for Teaching in a Real-World Context With Microbiology
Gordy, C. L., Ramirez, M. V., Vandegrift, M., & Goller, C. C. (2021, October 13). FRONTIERS IN MICROBIOLOGY, Vol. 12.
author keywords: microbiology; bioinformatics; educational studies; open education; undergraduate learning; sharing; quantitative skills
Sources: Web Of Science, ORCID
Added: November 15, 2021
2021 conference paper
HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible
Poster presented at the 2021 Biology and Mathematics Educators (BIOME) Institute.
Event: 2021 Biology and Mathematics Educators (BIOME) Institute
Sources: Crossref, ORCID
Added: October 4, 2021
2021 journal article
HITS: Harnessing a Collaborative Training Network to Create Case Studies that Integrate High-Throughput, Complex Datasets into Curricula
Frontiers in Education, 6, 711512.
author keywords: high-throughput; collaborative network; data analyses; quantitative skills; pedagogical case studies
TL;DR:
The rationale for engaging students in HT science, the authors' HT cases, and network model are shared to encourage other life science educators to join us and further develop and integrate HT complex datasets into curricula.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: June 6, 2022
2021 journal article
Integrating Bioinformatics Tools into Inquiry-based Molecular Biology Laboratory Education Modules
Frontiers in Education, 6.
author keywords: bioinformatics; science education; molecular biotechnology; software tools; case studies
TL;DR:
This new paradigm for biology laboratory education that embraces bioinformatics as a critical component of inquiry-based learning for undergraduate and graduate students representing the life sciences, the physical sciences, and engineering is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 23, 2021
2021 conference paper
Leveraging instructor involvement to enhance student engagement via social annotation
Whitham, J., Goller, C., & McKenney, E. (2021, May). Presented at the Lilly Conference Online.
Event: Lilly Conference Online
Source: NC State University Libraries
Added: May 21, 2022
2021 speech
Liquid Margins 20: Making Sense of Science With Social Annotation
Goller, C., McKenney, E. A., & McCartney, M. (2021, March).
Event: on March 12, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 journal article
New Tricks for Old Drugs: Using High-throughput Screening to Repurpose FDA-Approved Drugs to Combat Zika Virus
National Center for Case Study Teaching in Science. https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1194&id=1194
Source: NC State University Libraries
Added: September 27, 2021
2021 speech
Of all the bacteria around us... why Delftia? A BIT of an introduction to Biotechnology
Goller, C. C. (2021, November). Presented at the CPCC Research Club, Central Piedmont Community College.
Event: CPCC Research Club at Central Piedmont Community College on November 11, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Promoting a Culture of Co-Creation and Equity through Course WordPress Sites on Advanced Molecular Technologies
Goller, C. (2021, October 20). Presented at the OpenEd 2021 Conference.
Event: OpenEd 2021 Conference on October 20, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Publishing your evidence-based teaching activity in CourseSource: a step-by-step workshop for preparing your lesson manuscript
Goller, C., & Vinson, E. (2021, June 25). Presented at the American Society for Microbiology Conference for Undergraduate Educators (ASMCUE).
Event: American Society for Microbiology Conference for Undergraduate Educators (ASMCUE) on June 25, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Reimagining Open Education Leadership to Center Historically Marginalized Communities and Students
Goller, C., Ortiz, R., Tyler, D., Zenon, E., Grewe, K., & Cangialosi, K. (2021, October 18). Presented at the OpenEd 2021 Conference.
Event: OpenEd 2021 Conference on October 18, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 journal article
Scientists Offering Solutions through Sprints
QUBES Educational Resources.
Contributors: D. Rook
Sources: Crossref, ORCID
Added: May 16, 2022
2021 conference paper
Searching for Silver and Gold: Teaching students how to analyze microbial communities with KBase narratives
Whitham, W., Boland, M., Krebs, R., & Goller, C. (2021, February 26). Presented at the NC State Office of Faculty Development Teaching and Learning Symposium 2021.
Event: NC State Office of Faculty Development Teaching and Learning Symposium 2021 on February 26, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Searching for Silver and Gold: Teaching students how to analyze microbial communities with KBase narratives
Whitham, W., Boland, M., Krebs, R., & Goller, C. (2021, January 16). Poster presented at the Mid-Atlantic SENCER Center for Innovation Conference.
Event: Mid-Atlantic SENCER Center for Innovation Conference on January 16, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 journal article
Sharing Notes is Encouraged: Annotating and Co-creating with Hypothes.is and Google Docs
Journal of Microbiology & Biology Education, 22(1).
TL;DR:
Based on the evaluation of annotations, notes, and assessments, it is concluded that these activities encourage student engagement and achievement of learning outcomes while raising awareness of the importance of open and collaborative practices.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: March 15, 2021
2021 journal article
Sharing Stories: Developing OER around Podcasts
QUBES Educational Resources.
Contributors: D. Rook
Sources: Crossref, ORCID
Added: May 16, 2022
2021 speech
Show me the Open Science: Dissecting Publishing Contracts
Goller, C. C., Simon, M., Vandegrift, M., & Cross, W. (2021, October).
Event: on October 22, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Silver and Gold: Students Learn to Analyze Metagenomes with Kbase
Whitham, J., Boland, M., Krebs, R., & Goller, C. (2021, May). Presented at the Lilly Online Conference.
Event: Lilly Online Conference
Source: NC State University Libraries
Added: May 21, 2022
2021 journal article
Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
CourseSource, 8.
TL;DR:
This case provides a practical exercise in the use of high-throughput data analysis to explore the molecular basis of cancer at the level of single cells.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 27, 2021
2021 conference paper
Social annotation builds classroom community and confidence
McKenney, E. A., Hamon, L., & Goller, C. (2021, February 26). Presented at the NC State Office of Faculty Development Teaching and Learning Symposium 2021.
Event: NC State Office of Faculty Development Teaching and Learning Symposium 2021 on February 26, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Supporting Open Education Leadership that Promotes Social Justice and Empowers Underserved Students
Canglioso, K., Goller, C., & Zenon, E. (2021, August 11). Presented at the Michigan OER Summit.
Event: Michigan OER Summit on August 11, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
The Career Educator: Getting Your Dream Job
Presented at the American Society for Microbiology Conference for Undergraduate Educators (ASMCUE).
Event: American Society for Microbiology Conference for Undergraduate Educators (ASMCUE)
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
The Ideal Brew: Student-Created Case Studies for Course Improvement
Calzini, M., Goller, C., & Gordy, C. (2021, May). Poster presented at the Lilly Online Conference.
Event: Lilly Online Conference
Source: NC State University Libraries
Added: May 21, 2022
2021 journal article
Three steps to adapt case studies for synchronous and asynchronous online learning
Journal of Microbiology and Biology Education, 22(1), ev22i1-2337.
TL;DR:
This work describes functional examples of a three-step process to prepare cases with defined outcomes for individual student preparation, collaborative learning, and individual student synthesis to create an inclusive learning experience, whether in a traditional or remote learning environment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, ORCID
Added: June 21, 2021
2021 conference paper
Using Open Education to Precipitate Gold Nuggets of Wisdom: An Open Pedagogy Model for Crowdsourcing Notes and Citizen Science Research Using Web-Annotation
Goller, C. (2021, July 12). Presented at the Open Education Southern Symposium (OESS).
Event: Open Education Southern Symposium (OESS) on July 12, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Using Open Educational Resources and Technology to Empower Communities of Undergraduate Scholars
Presented at the ALT Annual Conference 2021.
Event: ALT Annual Conference 2021 on September 8, 2021
Source: NC State University Libraries
Added: May 21, 2022
2021 conference paper
Using WikiEDU to Promote Open Access Science for Sustainable Microbial Biotechnology
Tahir, R., Ramilo, L., Lertjanyarak, T., Norman, D., & Goller, C. (2021, April 13). Presented at the National Conference on Undergraduate Research (NCUR) 2021 conference.
Event: National Conference on Undergraduate Research (NCUR) 2021 conference on April 13, 2021
Source: NC State University Libraries
Added: May 21, 2022
2020 journal article
A CRISPR/Cas guide RNA design in silico activity
CourseSource, 7.
Sources: ORCID, Crossref
Added: December 30, 2020
2020 journal article
Aerobic biodegradation in freshwater and marine environments of textile microfibers generated in clothes laundering: Effects of cellulose and polyester-based microfibers on the microbiome
Marine Pollution Bulletin, 151, 110826.
author keywords: Biodegradability; Aquatic biodegradation; Cotton; Polyester; Rayon; Bacterial communities
MeSH headings : Biodegradation, Environmental; Cellulose; Clothing; Laundering; Microbiota; Polyesters; Textiles; Water Pollutants / analysis
TL;DR:
The bacterial diversity analyses in the different biodegradation inoculums show that there are distinct bacterial communities related to the assimilation and mineralization of complex carbohydrates that were promoted with the cellulosic MCC, cotton, and rayon samples different than the polyester sample.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: March 16, 2020
2020 conference paper
Analyzing the del Gene Cluster for Gold Biomineralization across Delftia spp
Presented at the North Carolina State University Summer 2020 Undergraduate Research Symposium, Raleigh, NC.
Event: North Carolina State University Summer 2020 Undergraduate Research Symposium at Raleigh, NC on July 30, 2020
Source: NC State University Libraries
Added: May 21, 2022
2020 speech
Beyond the Margins: Annotation and Re-Analysis of a Microbiome Study
Presented at the ITC Lilly Online.
Event: ITC Lilly Online on November 30 - December 4, 2020
Source: NC State University Libraries
Added: May 21, 2022
2020 conference paper
Building a Sustainable Open Community with the Open Pedagogy Incubator
Cross, W., Goller, C., McKenney, E., & Tully, D. (2020, November 12). Presented at the OpenEd.
Event: OpenEd on November 12, 2020
Source: NC State University Libraries
Added: May 21, 2022
2020 journal article
COVID-19: Where Did You Come From, Where Did You Go? National Center for Case Study Teaching in Science
National Center for Case Study Teaching in Science. https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1125&id=1125
Source: NC State University Libraries
Added: January 28, 2021
2020 journal article
Catalyzing rapid discovery of gold-precipitating bacterial lineages with university students
PeerJ, 8(4), e8925.
Contributors: N. Riley n, n , Z. Leggett n , D. Lewis n , K. Ciccone n & R. Dunn n
author keywords: Citizen science; Delftia; Microbiology; Bacterial lineages; Sequencing; Microbiology education; Undergraduate education; Public science; Metagenomics; Public engagement
TL;DR:
An interdisciplinary program to engage students from different courses in the sampling, identification and analysis of the DNA sequences of a unique yet common microbe, Delftia spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: ORCID, Crossref, Web Of Science
Added: April 15, 2020
2020 conference paper
Does a personalized and long-term teaching mentoring program actually work?
Moore, M. E., Swamy, U., Goller, C. C., Misra, A., Naganathan, A., Stieben, M. S., … Wick, S. (2020, July). Presented at the SABER 2020.
Event: SABER 2020
Source: NC State University Libraries
Added: May 21, 2022
2020 speech
Does open annotation enhance student performance and sense of belonging?
McKenney, E., & Goller, C. (2020, December). Poster presented at the ITC Lilly Online 2020.
Event: ITC Lilly Online 2020 on November 30 - December 4, 2020
Source: NC State University Libraries
Added: May 21, 2022
2020 journal article
Evolution of an 8‐week upper‐division metagenomics course: Diagramming a learning path from observational to quantitative microbiome analysis
Biochemistry and Molecular Biology Education, 48(4), 391–403.
MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Computational Biology / methods; Genome, Bacterial; Humans; Metagenomics / education; Metagenomics / methods; Microbiota; Problem-Based Learning / methods; RNA, Bacterial / analysis; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / analysis; RNA, Ribosomal, 16S / genetics; Soil Microbiology; Students
TL;DR:
This 8‐week metagenomics laboratory course has the objective of introducing upper‐level undergraduate and graduate students to strategies for designing, executing, and analyzing microbiome investigations and demonstrates that this approach provides an adaptable way to expose students to the cutting‐edge field of meetagenomics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: April 27, 2020
2020 journal article
Facilitating Long-Term Mentoring To Effectively Implement Active Learning Instruction: Formation of the Promoting Active Learning and Mentoring (PALM) Network †
Journal of Microbiology & Biology Education, 21(3).
TL;DR:
The foundation on which PALM was built is described and how a successful mentorship program can pave the way for educators to adapt and implement evidence-based practices like active learning in a college classroom is explained.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: ORCID, Crossref
Added: December 30, 2020
2020 journal article
Harnessing single‐stranded DNA binding protein to explore protein–protein and protein–DNA interactions
Biochemistry and Molecular Biology Education, 48(2), 181–190.
author keywords: ChIP; gamification; interaction; protein-ligand; yeast two-hybrid
MeSH headings : Binding Sites; Blotting, Western; Chromatin Immunoprecipitation; Curriculum; DNA, Single-Stranded / chemistry; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / isolation & purification; Educational Measurement; Female; Humans; Male; Microscopy, Fluorescence; Students; Surveys and Questionnaires
TL;DR:
A series of five experiments based on the robust bacterial single‐stranded DNA binding protein (SSB) to characterize both known and unknown protein–protein and protein–DNA interactions, which indicate a clear increase in both content knowledge and confidence in the topics presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref
Added: December 20, 2019
2020 conference paper
Harnessing the power of Nephele to engage students in microbiome analyses
Presented at the American Society for Microbiology Conference for Undergraduate Educators (ASMCUE).
Event: American Society for Microbiology Conference for Undergraduate Educators (ASMCUE)
Source: NC State University Libraries
Added: May 21, 2022
2020 conference paper
Implementing Citizen Science into the Classroom to Expose Undergraduate STEM and non-STEM Majors
Presented at the Citizen Science in Higher Education Symposium.
Event: Citizen Science in Higher Education Symposium on September 12, 2020
Source: NC State University Libraries
Added: May 21, 2022
2020 conference paper
Increasing the Online Presence of Delftia acidovorans through an Interactive, Accessible, and Engaging Web Hub
Ramilo, L., & Goller, C. (2020, July 30). Presented at the North Carolina State University Summer 2020 Undergraduate Research Symposium, Raleigh, NC.
Event: North Carolina State University Summer 2020 Undergraduate Research Symposium at Raleigh, NC on July 30, 2020
Source: NC State University Libraries
Added: May 21, 2022
2020 journal article
Integrating research into a molecular cloning course to address the evolving biotechnology landscape
Biochemistry and Molecular Biology Education, 7.
author keywords: calcium signaling; cellular biology; cloning; experimental design; inquiry-based laboratory; molecular biology
MeSH headings : Animals; Biotechnology / education; Calcium / metabolism; Cloning, Molecular; Curriculum; Fluorescent Dyes / chemistry; Humans; Proteins / analysis; Research; Students
TL;DR:
This existing molecular cloning course is redesigned to incorporate an independent research project assessing calcium signaling, and the framework described here provides a versatile structure that can be adapted to merge diverse instructor interests with evolving educational needs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: ORCID, Crossref
Added: July 28, 2020
2020 conference paper
The Why and How of Evidence-Based Teaching: Getting Fellowship Support from the PALM Network
Basta, H., Goller, C., Horak, R., & Waddell, E. (2020, October 22). Presented at the 2020 SACNAS The National Diversity in STEM Virtual Conference.
Event: 2020 SACNAS The National Diversity in STEM Virtual Conference on October 22, 2020
Source: NC State University Libraries
Added: May 21, 2022
2020 journal article
Using Metabolic Engineering to Connect Molecular Biology Techniques to Societal Challenges
Frontiers in Microbiology, 11.
author keywords: metabolic engineering; yeast; sustainability; case study; molecular biology; group work; agency; ownership
TL;DR:
An 8-week laboratory module for upper-division undergraduates and graduate students that builds upon students’ basic understanding of GMOs to introduce them to the techniques used to sustainably produce commercially valuable products in yeast through metabolic engineering, and an individual sustainability project assignment created for this course.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: ORCID, Crossref
Added: December 30, 2020
2019 journal article
Barriers to integration of bioinformatics into undergraduate life sciences education: A national study of US life sciences faculty uncover significant barriers to integrating bioinformatics into undergraduate instruction
PLOS ONE, 14(11), e0224288.
Ed(s): C. Bianchi
MeSH headings : Biology / education; Computational Biology / education; Curriculum; Faculty / statistics & numerical data; Female; Humans; Male; Motivation; Students / psychology; Surveys and Questionnaires / statistics & numerical data; United States
TL;DR:
It was surprised to discover that the cohort of faculty who were awarded their terminal degree most recently reported the most preparation in bioinformatics but teach it at the lowest rate, and Interestingly, the barriers faculty face depended strongly on whether they are members of an underrepresented group and on the Carnegie Classification of their home institution.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: June 1, 2020
2019 conference paper
Digging deeper in the pile... mortality composting
Haynes, M., & Goller, C. (2019, July 31). Presented at the North Carolina State University Summer 2019 Undergraduate Research Symposium, Raleigh, NC.
Event: North Carolina State University Summer 2019 Undergraduate Research Symposium at Raleigh, NC on July 31, 2019
Source: NC State University Libraries
Added: May 21, 2022
2019 conference paper
HITS: A network to promote high-throughput (HT) approaches through inquiry-based case studies
QUBES Educational Resources. Presented at the 2018 Annual Fall Conference for the National Center for Case Study Teaching In Science.
Event: 2018 Annual Fall Conference for the National Center for Case Study Teaching In Science
Sources: Crossref, ORCID
Added: January 5, 2021
2019 conference paper
HITS: Una red de educadores para la creación de casos para el estudio de tecnologías de alto rendimiento
Presented at the PAN-PBL 2019 Immersive Virtual International Conference.
Event: PAN-PBL 2019 Immersive Virtual International Conference on July 12-13, 2019
Source: NC State University Libraries
Added: May 21, 2022
2019 journal article
Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
CourseSource, 6.
Sources: ORCID, Crossref
Added: December 30, 2020
2019 journal article
Shifting Faculty Approaches to Pedagogy through Structured Teaching Postdoc Experiences
Journal of Microbiology & Biology Education, 20(2).
TL;DR:
The benefits of providing pedagogical training at the postdoctoral level are outlined and a framework for structuring an impactful teaching postdoc program is presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: February 27, 2020
2018 journal article
Bioinformatics core competencies for undergraduate life sciences education
PLOS ONE, 13(6), e0196878.
Ed(s): A. Dalby
MeSH headings : Adolescent; Adult; Computational Biology / education; Female; Humans; Male; Mental Competency; Problem-Based Learning; United States
TL;DR:
A set of bioinformatics core competencies for undergraduate life scientists developed using the results of a large national survey and the expertise of a working group ofBioinformaticians and educators are presented.
(via Semantic Scholar)
Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018
2018 speech
Delftia’s secrets: gold, mouthwash, and toxins
Presented at the Wolfpack Citizen Science Challenge, Raleigh, NC.
Event: Wolfpack Citizen Science Challenge at Raleigh, NC on April 11, 2018
Source: NC State University Libraries
Added: June 3, 2022
2018 conference paper
High-throughput screening and early drug development of potential antimicrobials against Delftia acidovorans
Presented at the North Carolina State University Spring Undergraduate Research Symposium, Raleigh, NC.
Event: North Carolina State University Spring Undergraduate Research Symposium at Raleigh, NC on April 18, 2018
Source: NC State University Libraries
Added: June 3, 2022
2018 speech
Inspiring Young Scientists with Genomics Research Opportunities
Presented at the St. Augustine’s University.
Event: St. Augustine’s University on February 6, 2018
Source: NC State University Libraries
Added: June 3, 2022
2018 speech
Outbreaks, metagenomics, and food science
Presented at the Food Microbiology class, North Carolina State University, Raleigh, NC.
Event: Food Microbiology class, North Carolina State University at Raleigh, NC on February 13, 2018
Source: NC State University Libraries
Added: June 3, 2022
2018 conference paper
Using the Allen Cell Explorer to introduce high-throughput approaches & image analysis through interrupted case studies
Using the Allen Cell Explorer to introduce high-throughput approaches & image analysis through interrupted case studies. Presented at the The 2018 ASCB | EMBO Meeting, San Diego, CA.
Event: The 2018 ASCB | EMBO Meeting at San Diego, CA on December 8-12, 2018
Source: NC State University Libraries
Added: June 3, 2022
2018 speech
Where do we go to find fascinating microbes? Not very far...
Goller, C. C., & Riley, N. (2018, January). Presented at the Wolfpack Citizen Science Challenge, Raleigh, NC.
Event: Wolfpack Citizen Science Challenge at Raleigh, NC on January 20, 2018
Source: NC State University Libraries
Added: June 3, 2022
2017 article
Barriers to Integration of Bioinformatics into Undergraduate Life Sciences Education
Williams, J., Drew, J., Galindo-Gonzalez, S., Robic, S., Dinsdale, E., Morgan, W., … Pauley, M. (2017, October 19). (Vol. 10). Vol. 10.
TL;DR:
An extensive survey of life sciences faculty in the United States found that the cohort of faculty with the most recently awarded PhD degrees reported the most training but were teaching bioinformatics at a lower rate than faculty who earned their degrees in previous decades.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2020
2017 speech
From microscopes to personalized medicine: Microbiomes and Cancer Biology
Goller, C. (2017, February). Guest lecture presented at the Cancer Biology course at High Point University,
Event: Cancer Biology course at High Point University, on February 27, 2017
Source: NC State University Libraries
Added: June 3, 2022
2017 conference paper
High-throughput screening of oncology drugs as potential antibiotics against Delftia acidovorans
Presented at the North Carolina State University Summer 2017 Undergraduate Research Symposium, Raleigh, NC.
Event: North Carolina State University Summer 2017 Undergraduate Research Symposium at Raleigh, NC on August 1, 2017
Source: NC State University Libraries
Added: June 3, 2022
2017 speech
Inspiring Young Deaf Scientists: NC State Research Opportunities. Next-generation sequencing and BIT SURE
Keynote presented at the NC School for the Deaf, Morganton, NC.
Event: NC School for the Deaf at Morganton, NC on November 10, 2017
Source: NC State University Libraries
Added: June 3, 2022
2017 conference paper
Metagenomic analyses of gutter and amphibian microbiomes from environmental swab samples using high-throughput 16S amplification and sequencing
Presented at the North Carolina State University Summer 2017 Undergraduate Research Symposium, Raleigh, NC.
Event: North Carolina State University Summer 2017 Undergraduate Research Symposium at Raleigh, NC on August 1, 2017
Source: NC State University Libraries
Added: June 3, 2022
2017 speech
Metagenomics in Food Microbiology
Guest lecture presented at the Food Science course, North Carolina State University, Raleigh, NC.
Event: Food Science course, North Carolina State University at Raleigh, NC on February 14, 2017
Source: NC State University Libraries
Added: June 3, 2022
2017 speech
Mi viaje como científico
Goller, C. C. (2017, November). Presented at the NC School for the Deaf, Morganton, NC.
Event: NC School for the Deaf at Morganton, NC on November 10, 2017
Source: NC State University Libraries
Added: June 3, 2022
2017 journal article
Unique Down to Our Microbes—Assessment of an Inquiry-Based Metagenomics Activity †
Journal of Microbiology & Biology Education, 18(2).
TL;DR:
An inquiry-based activity designed for introductory life science majors and nonmajors, students perform an investigation of the bacterial communities inhabiting the human belly button and associated metagenomics data collected through a citizen science project and visualized using an open-access bioinformatics tool.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref
Added: December 30, 2020
2017 journal article
Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course
CourseSource, 4.
TL;DR:
Students first familiarize themselves with the format of QIIME commands with a worksheet that deconstructs a command to help students understand the input, output, and arguments, and build student confidence in their ability to analyze high-throughput sequencing results of metagenomic datasets with the open-source QIime pipeline.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: December 30, 2020
2017 journal article
What is Recklessness in Scientific Research? The Frank Sauer Case
Accountability in Research, 24(8), 497–502.
author keywords: Collaboration; data management; misconduct in research; research ethics; research integrity; science policy
MeSH headings : Ethics, Research; Research Support as Topic / ethics; Research Support as Topic / legislation & jurisprudence; Scientific Misconduct / legislation & jurisprudence; United States; United States Office of Research Integrity / legislation & jurisprudence
TL;DR:
The case raises some interesting and important questions concerning research integrity because it focused on the legal issue of what constitutes recklessness in scientific research.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
16. Peace, Justice and Strong Institutions
(OpenAlex)
Sources: ORCID, Crossref
Added: December 30, 2020
2016 conference paper
BITS of Metagenomics
Presented at the Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE) conference, Omaha, Nebraska.
Event: Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE) conference at Omaha, Nebraska on August 5, 2016
Source: NC State University Libraries
Added: June 3, 2022
2016 speech
Exploring the Wildlife of Our Homes through Web-based Visualizations
Presented at the NC State Coffee & Viz series. Hunt Library, North Carolina State University, Raleigh, NC.
Event: NC State Coffee & Viz series. Hunt Library, North Carolina State University at Raleigh, NC on November 4, 2016
Source: NC State University Libraries
Added: June 3, 2022
2016 journal article
Threading the Needle: Small-Molecule Targeting of a Xenobiotic Receptor to Ablate Escherichia coli Polysaccharide Capsule Expression Without Altering Antibiotic Resistance
Journal of Infectious Diseases, 213(8), 1330–1339.
author keywords: E. coli; polysaccharide capsule; multidrug efflux pumps; small-molecule capsule inhibitor
MeSH headings : Animals; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacterial Capsules / drug effects; Bacterial Capsules / metabolism; Disease Models, Animal; Drug Discovery / methods; Drug Resistance, Multiple, Bacterial; Escherichia coli Infections / microbiology; Escherichia coli Proteins / antagonists & inhibitors; Escherichia coli Proteins / genetics; Female; Gene Knockdown Techniques / methods; Mice; Mice, Inbred C57BL; Repressor Proteins / antagonists & inhibitors; Repressor Proteins / genetics; Uropathogenic Escherichia coli / drug effects; Uropathogenic Escherichia coli / genetics; Virulence
TL;DR:
MprA regulates UPEC polysaccharide encapsulation, is essential for UPEC virulence, and can be targeted without inducing antibiotic resistance.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 30, 2020
2014 journal article
A Modern Twist on the Beaumont and St. Martin Case: Encouraging Analysis and Discussion in the Bioethics Classroom with Reflective Writing and Concept Mapping †
Journal of Microbiology & Biology Education, 15(2), 229–231.
TL;DR:
An activity was developed to encourage reflection on a classical ethical dilemma between a patient, St. Martin, and his employer/caretaker, Beaumont and mirrored the course’s structured approach of using concept mapping and reflection to dissect ethical dilemmas.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: ORCID, Crossref
Added: December 30, 2020
2014 conference paper
Analyzing big data with simple flowcharts and questioning techniques
Poster presented at the 111th Annual meeting North Carolina Academy of Science, North Carolina Museum of Natural Sciences, Raleigh, NC.
Event: 111th Annual meeting North Carolina Academy of Science at North Carolina Museum of Natural Sciences, Raleigh, NC on March 29, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 conference paper
Delftia acidovorans induces a proinflammatory response in THP-1 monocyes
Poster presented at the State of North Carolina Undergraduate Research and Creativity Symposium, North Carolina State University, Raleigh, NC.
Event: State of North Carolina Undergraduate Research and Creativity Symposium at North Carolina State University, Raleigh, NC on November 22, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 speech
Golden nuggets: Research and discoveries from the teaching lab
Goller, C. C. (2014, October). Presented at the Shaw University, Raleigh, NC.
Event: Shaw University at Raleigh, NC on October 22, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 journal article
Lifting the Mask: Identification of New Small Molecule Inhibitors of Uropathogenic Escherichia coli Group 2 Capsule Biogenesis
PLoS ONE, 9(7), e96054.
Ed(s): M. Skurnik
MeSH headings : Animals; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacterial Capsules / metabolism; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Escherichia coli Infections / drug therapy; Escherichia coli Infections / pathology; Female; Humans; Mice; Urinary Tract Infections / drug therapy; Urinary Tract Infections / pathology; Uropathogenic Escherichia coli / metabolism
TL;DR:
This work has provided a conceptually new class of molecules to combat UPEC infection, and future studies will establish the molecular basis for their action along with efficacy in UTI and other UPEC infections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref
Added: December 30, 2020
2014 speech
Metagenomics
Goller, C. C. (2014, February). Presented at the BIT 815: Deep Sequencing, North Carolina State Univeristy, Raleigh, NC.
Event: BIT 815: Deep Sequencing, North Carolina State Univeristy at Raleigh, NC on February 3, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 speech
Moving DNA around: Introduction to Biotechnology
Goller, C. C. (2014, April). Presented at the BIO 110: Principles of Biology. Wake Technical Community College, Raleigh, NC.
Event: BIO 110: Principles of Biology. Wake Technical Community College at Raleigh, NC on April 14, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 conference paper
Multiplex PCR as a Tool for the Detection of Delftia acidovorans
Poster presented at the North Carolina State University Summer Undergraduate Research Symposium, Raleigh, NC.
Event: North Carolina State University Summer Undergraduate Research Symposium at Raleigh, NC on July 30, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 conference paper
PCR detection of Delftia acidovorans in Samples from Sinks
Poster presented at the North Carolina State University Summer Undergraduate Research Symposium, Raleigh, NC.
Event: North Carolina State University Summer Undergraduate Research Symposium at Raleigh, NC on July 30, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 speech
The wildlife around us and the fascinating questions we can ask using biotechnology techniques
Goller, C. C. (2014, October). Presented at the Biomanufacturing Training and Education Center (BTEC), North Carolina State University, Raleigh, NC.
Event: Biomanufacturing Training and Education Center (BTEC) at North Carolina State University, Raleigh, NC on October 3, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 speech
What scientists and engineers write
Goller, C. C. (2014, February). Presented at the ENG 101 Featuring Scientists and Engineers in the Writing Class Program, North Carolina State University, Raleigh, NC.
Event: ENG 101 Featuring Scientists and Engineers in the Writing Class Program, North Carolina State University at Raleigh, NC on February 11, 2014
Source: NC State University Libraries
Added: June 3, 2022
2014 speech
Writing in the sciences and translations
Goller, C. C. (2014, February). Presented at the FLE 402: Advanced Written Communication in English for International Students, North Carolina State University, Raleigh, NC.
Event: FLE 402: Advanced Written Communication in English for International Students, North Carolina State University at Raleigh, NC on February 19, 2014
Source: NC State University Libraries
Added: June 3, 2022
2013 journal article
3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl) thiophene-2-carboxylic acid inhibits E.coli UT189 bacterial capsule biogenesis
https://www.ncbi.nlm.nih.gov/books/NBK143534
Source: ORCID
Added: December 30, 2020
2013 speech
Biofilms and Bioremediation
Presented at the BIT 100: Topics in Biotechnology, North Carolina State University, Raleigh, NC.
Event: BIT 100: Topics in Biotechnology, North Carolina State University at Raleigh, NC on September 4, 2013
Source: NC State University Libraries
Added: June 3, 2022
2013 journal article
N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide inhibits E. coli UT189 bacterial capsule biogenesis
https://www.ncbi.nlm.nih.gov/books/NBK148500
Source: ORCID
Added: December 30, 2020
2013 conference paper
Uncovering the biodiversity in Lake Raleigh utilizing bioinformatics and deep sequencing
Poster presented at the State of North Carolina Undergraduate Research and Creativity Symposium, Charlotte, NC.
Event: State of North Carolina Undergraduate Research and Creativity Symposium at Charlotte, NC on November 16, 2013
Source: NC State University Libraries
Added: June 3, 2022
2013 speech
What I write
Goller, C. C. (2013, September). Presented at the ENG 101, Featuring Scientists and Engineers in the Writing Class Program, North Carolina State University, Raleigh, NC.
Event: ENG 101, Featuring Scientists and Engineers in the Writing Class Program, North Carolina State University at Raleigh, NC on September 25, 2013
Source: NC State University Libraries
Added: June 3, 2022
2013 speech
What/how do scientists and engineers write to learn?
Presented at the Campus Writing & Speaking Program’s Brown Bag Lunch, North Carolina State University, Raleigh NC.
Event: Campus Writing & Speaking Program’s Brown Bag Lunch, North Carolina State University at Raleigh NC on November 18, 2013
Source: NC State University Libraries
Added: June 3, 2022
2012 report
3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl) thiophene-2-carboxylic acid inhibits E.coli UT189 bacterial capsule biogenesis
In Probe Reports from the NIH Molecular Libraries Program. https://www.ncbi.nlm.nih.gov/books/NBK143534/
Source: NC State University Libraries
Added: January 28, 2021
2012 journal article
Coming of AGE
Virulence, 3(1), 12–14.
author keywords: Salmonella; gene expression; vaccine; AGE; attenuated
MeSH headings : Animals; Escherichia coli Proteins / genetics; Female; Gene Expression; Humans; Molecular Chaperones / genetics; Salmonella Infections / microbiology; Salmonella typhimurium / genetics; Salmonella typhimurium / immunology; Virulence Factors / genetics
TL;DR:
The generation of live attenuated vaccines would be greatly facilitated by novel, portable approaches for attenuating Gram-negative pathogens.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: December 30, 2020
2012 journal article
N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide inhibits E. coli UT189 bacterial capsule biogenesis
Probe Reports from the NIH Molecular Libraries Program. https://www.ncbi.nlm.nih.gov/books/NBK148500/
Source: NC State University Libraries
Added: January 30, 2021
2010 journal article
High-Throughput Identification of Chemical Inhibitors of E. coli Group 2 Capsule Biogenesis as Anti-Virulence Agents
PLoS ONE, 5(7), e11642.
Ed(s): D. Ojcius
MeSH headings : Anti-Bacterial Agents / pharmacology; Antigens, Bacterial / drug effects; Antigens, Bacterial / metabolism; Antigens, Surface / drug effects; Antigens, Surface / metabolism; Bacterial Capsules / drug effects; Bacterial Capsules / metabolism; Escherichia coli / drug effects; Escherichia coli / metabolism; Escherichia coli / pathogenicity; Humans; Virulence / drug effects
TL;DR:
A screen for anti-capsular small molecules was conducted and an agent designated “C7” was identified that blocks the production of K1 and K5 capsules, unrelated polysaccharide types among the Group 2–3 capsules.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: December 30, 2020
2010 journal article
Polysaccharide Capsule and Sialic Acid-Mediated Regulation Promote Biofilm-Like Intracellular Bacterial Communities during Cystitis
Infection and Immunity, 78(3), 963–975.
MeSH headings : Animals; Bacterial Capsules / metabolism; Biofilms / growth & development; Colony Count, Microbial; Cystitis / immunology; Cystitis / microbiology; Cystitis / pathology; Disease Models, Animal; Mice; Mice, Knockout; N-Acetylneuraminic Acid / metabolism; Signal Transduction; Toll-Like Receptor 4 / deficiency; Urinary Tract Infections / microbiology; Uropathogenic Escherichia coli / pathogenicity; Virulence
TL;DR:
It is suggested that capsule is necessary for efficient IBC formation and that aberrant sialic acid accumulation, resulting from disruption of K1 capsule assembly, produces a NanR-mediated defect in intracellular proliferation and IBC development.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: December 30, 2020
2010 journal article
Revisiting the Escherichia coli polysaccharide capsule as a virulence factor during urinary tract infection: Contribution to intracellular biofilm development
Virulence, 1(4), 333–337.
author keywords: Escherichia coli; polysaccharide; capsule; sialic acid; urinary tract infection; biofilm; IBC; virulence; intra-cellularbacterial communities
MeSH headings : Animals; Bacterial Capsules / metabolism; Biofilms / growth & development; Cytosol / microbiology; Escherichia coli Infections / microbiology; Humans; Mice; N-Acetylneuraminic Acid / metabolism; Urinary Tract Infections / microbiology; Uropathogenic Escherichia coli / growth & development; Uropathogenic Escherichia coli / pathogenicity; Virulence; Virulence Factors / metabolism
TL;DR:
Evidence is provided for an expanded role for K capsule in the intracellular and extracellular pathogenesis of UTI, and additional rationale for the development of small molecule inhibitors of capsule biogenesis as anti-virulence therapeutics is provided.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref
Added: December 30, 2020
2010 conference paper
Role of the sialic acid regulator NanR of Uropathogenic Escherichia coli in urinary tract infections
Poster presented at the Duke University Pediatrics Division Research Retreat, Durham, NC.
Event: Duke University Pediatrics Division Research Retreat at Durham, NC on March 20, 2010
Source: NC State University Libraries
Added: June 3, 2022
2009 conference paper
Inhibitors of Bacterial Capsules as Novel Therapeutic for Urinary Tract Infections
Poster presented at the Duke University Pediatrics Division Research Retreat, Durham, NC.
Event: Duke University Pediatrics Division Research Retreat at Durham, NC on June 20, 2009
Source: NC State University Libraries
Added: June 3, 2022
2008 journal article
Environmental influences on biofilm development.
Current Topics in Microbiology and Immunology.
MeSH headings : Bacterial Adhesion / physiology; Bacterial Physiological Phenomena; Biofilms / growth & development; Chemotaxis / physiology; Ecosystem; Humans; Polysaccharides, Bacterial / physiology; Surface Properties
TL;DR:
This chapter will present examples of how environmental conditions affect biofilm development, most of which come from studies of species that have mammalian hosts.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2020
2008 conference paper
PGA Accumulation and Biofilm Formation in Escherichia coli: Modulation by c-di-GMP
Poster presented at the 108th General Meeting of the American Society for Microbiology, Boston, MA.
Event: 108th General Meeting of the American Society for Microbiology at Boston, MA on June 1-5, 2008
Source: NC State University Libraries
Added: June 3, 2022
2008 journal article
Roles of pgaABCD Genes in Synthesis, Modification, and Export of the Escherichia coli Biofilm Adhesin Poly-β-1,6-N-Acetyl-d-Glucosamine
Journal of Bacteriology, 190(10), 3670–3680.
MeSH headings : Adhesins, Escherichia coli / biosynthesis; Adhesins, Escherichia coli / metabolism; Amidohydrolases / physiology; Biofilms; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli / physiology; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Escherichia coli Proteins / physiology; Gene Expression Regulation, Bacterial; Microscopy, Immunoelectron; Operon / genetics; Polysaccharides / biosynthesis; beta-N-Acetylhexosaminidases / physiology
TL;DR:
Covalent modification of beta-1,6-GlcNAc by N-deacetylation serves distinct biological functions in gram-negative and gram-positive species, dictated by cell envelope differences.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: December 30, 2020
2006 journal article
The Cation-Responsive Protein NhaR of Escherichia coli Activates pgaABCD Transcription, Required for Production of the Biofilm Adhesin Poly-β-1,6-N-Acetyl-d-Glucosamine
Journal of Bacteriology, 188(23), 8022–8032.
MeSH headings : Adaptation, Physiological; Adhesins, Bacterial / genetics; Adhesins, Bacterial / metabolism; Antigens, Bacterial / genetics; Base Sequence; Biofilms / growth & development; Cations; DNA, Bacterial / genetics; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; DNA-Binding Proteins / physiology; Escherichia coli / genetics; Escherichia coli / physiology; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Escherichia coli Proteins / physiology; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Molecular Sequence Data; Operon / genetics; Promoter Regions, Genetic / physiology; Protein Binding; RNA, Bacterial / genetics; RNA, Messenger / genetics; Sodium Chloride / pharmacology; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription Factors / physiology; Transcription, Genetic
TL;DR:
A novel mechanism for regulation of biofilm formation in response to environmental conditions is defined and an expanded role for NhaR is suggested in promoting bacterial survival.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: December 30, 2020
2002 journal article
Economics of cage culture in Puerto Rico
Aquaculture Economics & Management, 6(5-6), 363–372.
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: ORCID, Crossref
Added: December 30, 2020
Employment
Updated: September 4th, 2021 17:13
2020 - present
North Carolina State University Raleigh, NC, US
Associate Teaching Professor
Biological Sciences
2015 - 2020
North Carolina State University Raleigh, NC, US
Assistant Teaching Professor
Biological Sciences
Education
Updated: November 30th, 2021 22:29
2012 - 2015
North Carolina State University Raleigh, NC, US
Postdoctoral Teaching Scholar
Biotechnology Program
2008 - 2012
Duke University Department of Pediatrics Durham, NC, US
The Hartwell Foundation Postdoctoral Fellow
Pediatrics Infectious Diseases
2002 - 2008
Emory University Atlanta, GA, US
Ph.D. in Microbiology and Molecular Genetics
Microbiology and Immunology
1998 - 2002
Worcester Polytechnic Institute Worcester, MA, US
BS Biology and Biotechnology
Biology and Biotechnology
Funding History
Funding history based on the linked ORCID record. Updated: April 22nd, 2024 23:38
grant
March 1, 2023 - February 28, 2026
Evaluating the impact of an open-data-based lessons and course-based research experiences on student knowledge, skills, and attitudes
Directorate for STEM Education
grant
January 1, 2023 - December 1, 2025
Collaborative Research: Evaluating the Impact of the Promoting Active Learning and Mentoring (PALM) Network on Vision
National Science Foundation
grant
July 1, 2022 - June 1, 2023
SCoOP: Sustainable Composting and Outreach Program. NC State Office of Sustainability, Sustainability Fund
North Carolina State University Sustainability Fund
grant
July 1, 2021 - June 1, 2022
MORE: Mentored, Open Research Experiences
Code for Science and Society, Inc.
grant
March 15, 2020 - February 28, 2025
Molecular Biotechnology Laboratory Education Modules (MBLEM)
National Institute of General Medical Sciences
grant
March 22, 2019
2019 HITS Summer Workshop
North Carolina Biotechnology Center
grant
September 15, 2017 - August 31, 2020
REU Site: BioTechnology Sequencing-based Undergraduate Research Experience (BIT SURE)
Directorate for Biological Sciences
grant
August 15, 2017 - July 31, 2022
RCN-UBE: HITS: High-throughput Discovery Science & Inquiry-based Case Studies for Today's Students
Directorate for Biological Sciences
grant
January 1, 2017
Do not fear the robot: bringing automation into the undergraduate classroom
NC STEM Initiative
grant
July 1, 2005 - June 30, 2008
MINORITY PREDOCTORAL FELLOWSHIP PROGRAM
National Institute of Allergy and Infectious Diseases
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