Carlos Christopher Goller

Also known as: Carlos Goller

https://orcid.org/0000-0002-2013-0334

high-throughput approaches, molecular biology, microbiology, molecular biology education, metagenomics, open educational resources, open educational practices, Delftia

I was born in Mexico and grew up in the city of San Miguel de Allende, Guanajuato. My father was a retired US NAVY Lt. Cdr., and my mother is a retired elementary school teacher who taught for forty years. I attended a bilingual elementary school and then a technical high school in Queretaro (ITESM Campus Queretaro). Thanks to a high school biology teacher named Gabriela Corral, I learned about biotechnology. I was captivated by viruses and bacteria and determined to study biotechnology as a major. Despite my poor guidance counselor trying to convince me to major in physics with a full scholarship at the ITESM, I took a bus several times to Mexico City to take the SAT & SAT subject tests and went to the Benjamin Franklin Library to read about college applications. I applied to several colleges & universities in the United States and attended Worcester Polytechnic Institute in Worcester, MA where I majored in Biology and Biotechnology (yes!). Dr. Jeff Tyler provided a wonderful experience and acted as a superb mentor. I learned about population-based modeling and coding. With Dr. Jose Arguello, I cloned my first bacterial gene. These two undergraduate research experiences convinced me I wanted to pursue a Ph.D. in microbial genetics. My interest in public health and... viruses took me to Emory (next to the CDC) in Atlanta. I was fortunate to join the lab of Dr. Tony Romeo, an incredible bacterial geneticist. I was also lucky to stumble upon Dr. Pat Marsteller and Dr. Arri Eisen who taught me about the joy of reformed teaching and science and society. At Duke, Dr. Pat Seed (the first author of a study I had presented as a journal club topic during graduate school) taught me about the thrill of high-throughput discovery. I was then able to combine teaching and research at North Carolina State University.

Works (40)

2021 journal article

Divide and Conquer: A Simple Modern Technique for Collaborative Small Group Learning with Reciprocal Peer Teaching

Journal of Microbiology and Biology Education, 22(1), ev22i1-2153.

By: L. Samsa & C. Goller

Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 21, 2021

2021 conference paper

HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible

Poster presented at the 2021 Biology and Mathematics Educators (BIOME) Institute.

By: C. Goller & S. Robertson

Event: 2021 Biology and Mathematics Educators (BIOME) Institute

Sources: Crossref, ORCID
Added: October 4, 2021

2021 journal article

Integrating Bioinformatics Tools Into Inquiry-Based Molecular Biology Laboratory Education Modules

FRONTIERS IN EDUCATION, 7.

By: C. Goller, M. Srougi, S. Chen, L. Schenkman & R. Kelly

Sources: Web Of Science, ORCID
Added: August 23, 2021

2021 journal article

New Tricks for Old Drugs: Using High-throughput Screening to Repurpose FDA-Approved Drugs to Combat Zika Virus

National Center for Case Study Teaching in Science. Retrieved from https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1194&id=1194

By: C. Goller, S. Chen & M. Srougi

Source: NC State University Libraries
Added: September 27, 2021

2021 journal article

Sharing Notes is Encouraged: Annotating and Co-creating with Hypothes.is and Google Docs

Journal of Microbiology & Biology Education, 22(1).

By: C. Goller, M. Vandegrift, W. Cross & D. Smyth

Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 15, 2021

2021 journal article

Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

CourseSource, 8.

By: L. Samsa, M. Eslinger, A. Kleinschmit, A. Solem & C. Goller

Sources: Crossref, ORCID
Added: September 27, 2021

2021 journal article

Three steps to adapt case studies for synchronous and asynchronous online learning

Journal of Microbiology and Biology Education, 22(1), ev22i1-2337.

By: A. Bixler, M. Eslinger, A. Kleinschmit, M. Gaudier-Diaz, U. Sankar, P. Marsteller, C. Goller, S. Robertson

Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 21, 2021

2020 journal article

A CRISPR/Cas guide RNA design in silico activity

CourseSource, 7.

By: L. Samsa, L. Andersen, A. Groth & C. Goller

Sources: ORCID, Crossref
Added: December 30, 2020

2020 journal article

Aerobic biodegradation in freshwater and marine environments of textile microfibers generated in clothes laundering: Effects of cellulose and polyester-based microfibers on the microbiome

Marine Pollution Bulletin, 151, 110826.

By: M. Zambrano, J. Pawlak, J. Daystar, M. Ankeny, C. Goller & R. Venditti

Sources: Web Of Science, ORCID, Crossref
Added: March 16, 2020

2020 journal article

COVID-19: Where Did You Come From, Where Did You Go? National Center for Case Study Teaching in Science

National Center for Case Study Teaching in Science. Retrieved from https://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1125&id=1125

By: S. Chen, C. Goller & M. Srougi

Source: NC State University Libraries
Added: January 28, 2021

2020 journal article

Catalyzing rapid discovery of gold-precipitating bacterial lineages with university students

PeerJ, 8, e8925.

By: N. Riley, C. Goller, Z. Leggett, D. Lewis, K. Ciccone & R. Dunn

Sources: ORCID, Crossref
Added: December 30, 2020

2020 journal article

Evolution of an 8‐week upper‐division metagenomics course: Diagramming a learning path from observational to quantitative microbiome analysis

Biochemistry and Molecular Biology Education, 48(4), 391–403.

By: C. Goller & L. Ott

Sources: Web Of Science, ORCID, Crossref
Added: April 27, 2020

2020 journal article

Facilitating Long-Term Mentoring To Effectively Implement Active Learning Instruction: Formation of the Promoting Active Learning and Mentoring (PALM) Network †

Journal of Microbiology & Biology Education, 21(3).

By: M. Moore, A. Naganathan, S. Blumer, C. Goller, A. Misra, S. Raut, U. Swamy, S. Wick, M. Wolyniak

Sources: ORCID, Crossref
Added: December 30, 2020

2020 journal article

Harnessing single‐stranded DNA binding protein to explore protein–protein and protein–DNA interactions

Biochemistry and Molecular Biology Education, 48(2), 181–190.

By: S. Chen & C. Goller

Sources: ORCID, Crossref
Added: December 30, 2020

2020 journal article

Integrating research into a molecular cloning course to address the evolving biotechnology landscape

Biochemistry and Molecular Biology Education, 7.

By: C. Garcia, I. Chapman, S. Chen, E. Lazear, T. Lentz, C. Williams, J. Dums, C. Goller, S. Robertson

Sources: ORCID, Crossref
Added: December 30, 2020

2020 journal article

Using Metabolic Engineering to Connect Molecular Biology Techniques to Societal Challenges

Frontiers in Microbiology, 11.

By: C. Gordy & C. Goller

Sources: ORCID, Crossref
Added: December 30, 2020

2019 journal article

Barriers to integration of bioinformatics into undergraduate life sciences education: A national study of US life sciences faculty uncover significant barriers to integrating bioinformatics into undergraduate instruction

PLOS ONE, 14(11), e0224288.

By: J. Williams, J. Drew, S. Galindo-Gonzalez, S. Robic, E. Dinsdale, W. Morgan, E. Triplett, J. Burnette ...

Ed(s): C. Bianchi

Sources: Web Of Science, ORCID, Crossref
Added: June 1, 2020

2019 conference paper

HITS: A network to promote high-throughput (HT) approaches through inquiry-based case studies

QUBES Educational Resources. Presented at the 2018 Annual Fall Conference for the National Center for Case Study Teaching In Science.

By: C. Goller, S. Chen & S. Robertson

Event: 2018 Annual Fall Conference for the National Center for Case Study Teaching In Science

Sources: Crossref, ORCID
Added: January 5, 2021

2019 journal article

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

CourseSource, 6.

By: A. Kleinschmit, B. Brink, S. Roof, C. Goller & S. Robertson

Sources: ORCID, Crossref
Added: December 30, 2020

2019 journal article

Shifting Faculty Approaches to Pedagogy through Structured Teaching Postdoc Experiences

Journal of Microbiology & Biology Education, 20(2).

By: S. Chen & C. Goller

Sources: Web Of Science, ORCID, Crossref
Added: February 27, 2020

2018 journal article

Bioinformatics core competencies for undergraduate life sciences education

PLOS ONE, 13(6), e0196878.

By: M. Wilson Sayres, C. Hauser, M. Sierk, S. Robic, A. Rosenwald, T. Smith, E. Triplett, J. Williams ...

Ed(s): A. Dalby

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 article

Barriers to Integration of Bioinformatics into Undergraduate Life Sciences Education

Williams, J., Drew, J., Galindo-Gonzalez, S., Robic, S., Dinsdale, E., Morgan, W., … Pauley, M. (2017, October 19). (Vol. 10). Vol. 10.

By: J. Williams, J. Drew, S. Galindo-Gonzalez, S. Robic, E. Dinsdale, W. Morgan, E. Triplett, J. Burnette ...

Source: ORCID
Added: December 30, 2020

2017 journal article

Unique Down to Our Microbes—Assessment of an Inquiry-Based Metagenomics Activity †

Journal of Microbiology & Biology Education, 18(2).

By: T. Lentz, L. Ott, S. Robertson, S. Windsor, J. Kelley, M. Wollenberg, R. Dunn, C. Goller

Sources: ORCID, Crossref
Added: December 30, 2020

2017 journal article

Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course

CourseSource, 4.

By: J. Stevens, R. DeHority & C. Goller

Sources: ORCID, Crossref
Added: December 30, 2020

2017 journal article

What is Recklessness in Scientific Research? The Frank Sauer Case

Accountability in Research, 24(8), 497–502.

By: D. Resnik, E. Smith, S. Chen & C. Goller

Sources: ORCID, Crossref
Added: December 30, 2020

2016 journal article

Threading the Needle: Small-Molecule Targeting of a Xenobiotic Receptor to Ablate Escherichia coli Polysaccharide Capsule Expression Without Altering Antibiotic Resistance

Journal of Infectious Diseases, 213(8), 1330–1339.

By: M. Arshad, C. Goller, D. Pilla, F. Schoenen & P. Seed

Sources: Crossref, ORCID
Added: December 30, 2020

2014 journal article

A Modern Twist on the Beaumont and St. Martin Case: Encouraging Analysis and Discussion in the Bioethics Classroom with Reflective Writing and Concept Mapping †

Journal of Microbiology & Biology Education, 15(2), 229–231.

By: C. Goller

Sources: ORCID, Crossref
Added: December 30, 2020

2014 journal article

Lifting the Mask: Identification of New Small Molecule Inhibitors of Uropathogenic Escherichia coli Group 2 Capsule Biogenesis

PLoS ONE, 9(7), e96054.

By: C. Goller, M. Arshad, J. Noah, S. Ananthan, C. Evans, N. Nebane, L. Rasmussen, M. Sosa ...

Ed(s): M. Skurnik

Sources: ORCID, Crossref
Added: December 30, 2020

2013 journal article

3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl) thiophene-2-carboxylic acid inhibits E.coli UT189 bacterial capsule biogenesis

Source: ORCID
Added: December 30, 2020

2013 journal article

N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide inhibits E. coli UT189 bacterial capsule biogenesis

Source: ORCID
Added: December 30, 2020

2012 report

3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl) thiophene-2-carboxylic acid inhibits E.coli UT189 bacterial capsule biogenesis

In Probe Reports from the NIH Molecular Libraries Program. Retrieved from National Center for Biotechnology Information website: https://www.ncbi.nlm.nih.gov/books/NBK143534/

By: J. Noah, S. Ananthan, C. Evans, N. Nebane, L. Rasmussen, M. Sosa, N. Tower, E. White ...

Source: NC State University Libraries
Added: January 28, 2021

2012 journal article

Coming of AGE

Virulence, 3(1), 12–14.

By: C. Goller & P. Seed

Sources: ORCID, Crossref
Added: December 30, 2020

2012 journal article

N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide inhibits E. coli UT189 bacterial capsule biogenesis

Probe Reports from the NIH Molecular Libraries Program. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK148500/

By: J. Noah, S. Ananthan, C. Evans, N. Nebane, L. Rasmussen, M. Sosa, N. Tower, E. White ...

Source: NC State University Libraries
Added: January 30, 2021

2010 journal article

High-Throughput Identification of Chemical Inhibitors of E. coli Group 2 Capsule Biogenesis as Anti-Virulence Agents

PLoS ONE, 5(7), e11642.

By: C. Goller & P. Seed

Ed(s): D. Ojcius

Sources: ORCID, Crossref
Added: December 30, 2020

2010 journal article

Polysaccharide Capsule and Sialic Acid-Mediated Regulation Promote Biofilm-Like Intracellular Bacterial Communities during Cystitis

Infection and Immunity, 78(3), 963–975.

By: G. Anderson, C. Goller, S. Justice, S. Hultgren & P. Seed

Sources: ORCID, Crossref
Added: December 30, 2020

2010 journal article

Revisiting the Escherichia coli polysaccharide capsule as a virulence factor during urinary tract infection: Contribution to intracellular biofilm development

Virulence, 1(4), 333–337.

By: C. Goller & P. Seed

Sources: ORCID, Crossref
Added: December 30, 2020

2008 journal article

Environmental influences on biofilm development.

Current Topics in Microbiology and Immunology.

Source: ORCID
Added: December 30, 2020

2008 journal article

Roles of pgaABCD Genes in Synthesis, Modification, and Export of the Escherichia coli Biofilm Adhesin Poly-β-1,6-N-Acetyl-d-Glucosamine

Journal of Bacteriology, 190(10), 3670–3680.

By: Y. Itoh, J. Rice, C. Goller, A. Pannuri, J. Taylor, J. Meisner, T. Beveridge, J. Preston, T. Romeo

Sources: ORCID, Crossref
Added: December 30, 2020

2006 journal article

The Cation-Responsive Protein NhaR of Escherichia coli Activates pgaABCD Transcription, Required for Production of the Biofilm Adhesin Poly-β-1,6-N-Acetyl-d-Glucosamine

Journal of Bacteriology, 188(23), 8022–8032.

By: C. Goller, X. Wang, Y. Itoh & T. Romeo

Sources: ORCID, Crossref
Added: December 30, 2020

2002 journal article

Economics of cage culture in Puerto Rico

Aquaculture Economics & Management, 6(5-6), 363–372.

By: J. Brown, C. Goller, T. Peters, A. Olean, S. Vernon‐Gerstenfeld & A. Gerstenfeld

Sources: ORCID, Crossref
Added: December 30, 2020

Employment

2020 - present

North Carolina State University Raleigh, NC, US
Associate Teaching Professor Biological Sciences

2015 - 2020

North Carolina State University Raleigh, NC, US
Assistant Teaching Professor Biological Sciences

Education

2012 - 2015

North Carolina State University Raleigh, NC, US
Postdoctoral Teaching Scholar Biotechnology Program

2008 - 2012

Duke University Department of Pediatrics Durham, NC, US
Hartwell Postdoctoral Fellow Pediatrics Infectious Diseases

2002 - 2008

Emory University Atlanta, GA, US
Ph.D. in Microbiology and Molecular Genetics Microbiology and Immunology

1998 - 2002

Worcester Polytechnic Institute Worcester, MA, US
BS Biology and Biotechnology Biology and Biotechnology

Funding History

Funding history based on the linked ORCID record.

grant July 1, 2021 - June 1, 2022
MORE: Mentored, Open Research Experiences
Code for Science and Society, Inc.
grant March 15, 2020 - February 28, 2025
Molecular Biotechnology Laboratory Education Modules (MBLEM)
National Institute of General Medical Sciences
grant March 22, 2019
2019 HITS Summer Workshop
North Carolina Biotechnology Center
grant September 15, 2017 - August 31, 2020
REU Site: BioTechnology Sequencing-based Undergraduate Research Experience (BIT SURE)
Directorate for Biological Sciences
grant August 15, 2017 - July 31, 2022
RCN-UBE: HITS: High-throughput Discovery Science & Inquiry-based Case Studies for Today's Students
Directorate for Biological Sciences
grant January 1, 2017
Do not fear the robot: bringing automation into the undergraduate classroom
NC STEM Initiative
grant July 1, 2005 - June 30, 2008
MINORITY PREDOCTORAL FELLOWSHIP PROGRAM
National Institute of Allergy and Infectious Diseases