Chongxiao (Sean) Chen

Also known as: Sean

Poultry Science

Works (23)

Updated: August 1st, 2023 21:16

2022 journal article

Determination of non-phytate phosphorus requirement for slow-growing feather-frizzled broilers from 1 to 21 days of age

ANIMAL FEED SCIENCE AND TECHNOLOGY, 291.

By: F. Yin*, C. Chen n , J. Chen*, X. He*, C. Xia* & R. Wang*

author keywords: Broiler; Non-phytate phosphorous; Growth performance; Bone quality; Serum; Carcass characteristics
Sources: Web Of Science, NC State University Libraries
Added: September 6, 2022

2022 journal article

Effects of Varying Levels of Dietary DL-Methionine Supplementation on Breast Meat Quality of Male and Female Broilers

Poultry, 1(1), 40–53.

By: A. Pokoo-Aikins *, J. Timmons *, B. Min *, W. Lee, S. Mwangi*, C. McDonough *, C. Chen n 

Source: ORCID
Added: March 22, 2022

2021 journal article

Effect of Age on Bone Structure Parameters in Laying Hens

ANIMALS, 11(2).

By: M. Yamada *, C. Chen n , T. Sugiyama* & W. Kim *

author keywords: laying hens; osteoporosis; medullary bone; aging
TL;DR: It is revealed that reductions in medullary bone quality might be associated with age-related low estrogen levels and stimulation of osteoclastic bone resorption by parathyroid hormone, with a longer egg-laying period leading to osteoporosis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 22, 2021

2021 journal article

Effects of Feeding Varying Levels of DL-Methionine on Live Performance and Yield of Broiler Chickens

ANIMALS, 11(10).

By: A. Pokoo-Aikins *, J. Timmons *, B. Min *, W. Lee, S. Mwangi* & C. Chen n 

author keywords: DL-methionine; amino acid; organic broilers; meat yield
TL;DR: Evaluating the effects of dietary supplemental DL-methionine (MET) on live performance and meat yield for broilers raised to a common weight found elimination of MET from organic broiler diets resulted in reduced ADG, breast fillet yield and feed efficiency of meat yield of broilersraised to day 46/48. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 30, 2021

2021 journal article

Effects of dietary protein, energy and beta-mannanase on laying performance, egg quality, and ileal amino acid digestibility in laying hens

POULTRY SCIENCE, 100(9).

By: D. White*, R. Adhikari *, J. Wang *, C. Chen n , J. Lee * & W. Kim *

author keywords: laying hen; beta-mannanase; feed intake; egg production; amino acid digestibility
MeSH headings : Amino Acids; Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Chickens; Dietary Proteins; Ovum; beta-Mannosidase
TL;DR: The results of these experiments indicate that supplementation of β-mannanase could reduce the feed intake and FCR and improve HDEP and apparent ileal digestibility of key amino acids in corn/soy diets fed to laying hens. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 6, 2021

2021 journal article

Effects of the housing environment and laying hen strain on tibia and femur bone properties of different laying phases of Hy-Line hens

Poultry Science, 100(3), 100933.

By: M. Sharma*, D. White*, C. Chen* , W. Kim * & P. Adhikari *

author keywords: bone property; housing environment; laying hen strain; X-ray microtomography
MeSH headings : Animal Husbandry; Animals; Chickens; Female; Femur; Housing, Animal; Tibia
TL;DR: It is suggested that raising laying hens in alternative housing systems that have provision for exercise such as FR reduces structural bone loss, stimulate structural bone formation, and improve breaking strength of bones; however, it varies with the strain. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities (OpenAlex)
Source: ORCID
Added: January 16, 2021

2021 journal article

Role of 25-Hydroxyvitamin D-3 and 1,25-Dihydroxyvitamin D-3 in Chicken Embryo Osteogenesis, Adipogenesis, Myogenesis, and Vitamin D-3 Metabolism

FRONTIERS IN PHYSIOLOGY, 12.

By: C. Chen n , D. White*, B. Marshall* & W. Kim *

author keywords: vitamin D-3; chicken embryo; osteogenesis; adipogenesis; myogenesis; metabolism; gene expression
TL;DR: The results suggested both 1,25OHD and 25OHD induced chicken embryo osteogenesis and adipogenesis, but inhibited myogenesis during early chicken embryo development. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: March 1, 2021

2020 journal article

25-Hydroxycholesterol Inhibits Adipogenic Differentiation of C3H10T1/2 Pluripotent Stromal Cells

International Journal of Molecular Sciences, 21(2), 412.

By: D. Moseti*, A. Regassa*, C. Chen* , O. Karmin* & W. Kim *

Contributors: D. Moseti*, A. Regassa*, C. Chen* , O. Karmin* & W. Kim *

author keywords: oxysterols; C3H10T1; 2 stromal cells; differentiation; hedgehog signalling; PPAR gamma; ADD1; SREBF1
MeSH headings : Adipogenesis / drug effects; Adipogenesis / genetics; Animals; Benzoates / pharmacology; Benzylamines / pharmacology; Cell Line; Gene Expression Regulation / drug effects; Hedgehog Proteins / genetics; Hedgehog Proteins / metabolism; Hydroxycholesterols / pharmacology; Lipid Metabolism / drug effects; Liver X Receptors / agonists; Liver X Receptors / metabolism; Mice; Oxysterols / pharmacology; Pluripotent Stem Cells / cytology; Pluripotent Stem Cells / drug effects; RNA, Messenger / genetics; RNA, Messenger / metabolism; Signal Transduction / drug effects; Stromal Cells / cytology; Stromal Cells / drug effects; Time Factors
TL;DR: It is reported that 25-HC was the most potent oxysterol in inhibiting adipogenesis and the expression of key adipogenic transcripts in C3H10T1/2 cells among the tested oxysterols, suggesting its potential application in providing an intervention in osteoporosis and obesity. (via Semantic Scholar)
Source: ORCID
Added: October 14, 2020

2020 journal article

Effect of 20(S)-Hydroxycholesterol on Multilineage Differentiation of Mesenchymal Stem Cells Isolated from Compact Bones in Chicken

GENES, 11(11).

By: R. Adhikari *, C. Chen n  & W. Kim *

author keywords: adipogenesis; chicken; mesenchymal stem cells; myogenesis; osteogenesis; 20(s)-hydroxycholesterol; hedgehog signaling
MeSH headings : Adipocytes / cytology; Adipocytes / drug effects; Adipogenesis / drug effects; Animals; Bone and Bones / cytology; Cell Differentiation / drug effects; Cell Lineage; Cells, Cultured; Chickens; Femur / cytology; Gene Expression Regulation / drug effects; Hedgehog Proteins / metabolism; Hydroxycholesterols / metabolism; Hydroxycholesterols / pharmacology; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Muscle Development / drug effects; Osteogenesis / drug effects; Oxysterols / pharmacology; Tibia / cytology
TL;DR: 20(S) could play an important role in the differentiation of chicken-derived MSCs and provided the theory basis on developing an intervention strategy to regulate skeletal, myogenic, and adipogenic differentiation in chicken, which will contribute to improving chicken bone health and meat quality. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: December 11, 2020

2020 journal article

Effects of Inorganic Zn and Cu Supplementation on Gut Health in Broiler Chickens Challenged With Eimeria spp.

Frontiers in Veterinary Science, 7.

By: T. Santos *, P. Teng *, S. Yadav *, F. Castro *, R. Gould*, S. Craig*, C. Chen* , A. Fuller* ...

Contributors: T. Santos *, P. Teng *, S. Yadav *, F. Castro *, R. Gould*, S. Craig*, C. Chen* , A. Fuller* ...

author keywords: broilers; coccidiosis; copper; gut health; zinc
TL;DR: It is shown that Cu and Zn supplementation improves intestinal integrity during the Eimeria spp. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2020 journal article

Effects of alpha-lipoic acid on the behavior, serum indicators, and bone quality of broilers under stocking density stress

Poultry Science, 99(10), 4653–4661.

By: H. Ma *, B. Xu *, W. Li *, F. Wei *, W. Kim *, C. Chen* , Q. Sun *, C. Fu *, G. Wang *, S. Li *

Contributors: H. Ma *, B. Xu *, W. Li *, F. Wei *, W. Kim *, C. Chen* , Q. Sun *, C. Fu *, G. Wang *, S. Li *

author keywords: broilers; stocking density; alpha-lipoic acid; behavior; bone quality
MeSH headings : Animal Feed / analysis; Animals; Antioxidants / pharmacology; Behavior, Animal / drug effects; Bone and Bones / drug effects; Chickens / blood; Dietary Supplements; Male; Population Density; Random Allocation; Stress, Physiological / drug effects; Thioctic Acid / blood; Thioctic Acid / pharmacology
TL;DR: The results indicate that the increase of stocking density lowered the bone quality, increased the physiological and oxidative stress indicators, and modified the behavior of broilers, whereas ALA dietary supplementation could counteract the reduction in the performance and physiological responses of broiler chicks under high-density environmental stress. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2020 journal article

Fatty Acid Composition and Regulatory Gene Expression in Late-Term Embryos of ACRB and COBB Broilers

Frontiers in Veterinary Science, 7.

By: S. Su*, Y. Wang *, C. Chen* , M. Suh *, M. Azain * & W. Kim *

Contributors: S. Su*, Y. Wang *, C. Chen* , M. Suh *, M. Azain * & W. Kim *

author keywords: breed; embryo; fatty acids; liver; muscle
TL;DR: Broiler breed affects egg, embryo, and tissue weight, as well as FA composition in initial egg yolk and throughout the embryonic development, indicating that genetic selection may result in fatty acid profile changes such as lower DHA content in chicken tissues and eggs. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2020 journal article

Impact of an alternate feeding program on broiler breeder pullet behavior, performance, and plasma corticosterone

Poultry Science, 99(2), 829–838.

By: C. Aranibar*, C. Chen* , A. Davis *, W. Daley*, C. Dunkley*, W. Kim *, C. Usher*, A. Webster*, J. Wilson*

Contributors: C. Aranibar*, C. Chen* , A. Davis *, W. Daley*, C. Dunkley*, W. Kim *, C. Usher*, A. Webster*, J. Wilson*

MeSH headings : Animal Feed / analysis; Animal Husbandry / methods; Animal Nutritional Physiological Phenomena; Animal Welfare; Animals; Chickens / blood; Chickens / growth & development; Chickens / physiology; Corticosterone / blood; Diet / veterinary; Feeding Behavior; Frustration; Random Allocation; Seeds / chemistry; Soybeans / chemistry
TL;DR: Overall, feeding the ATD females soybean hulls on the off feed day improved the BW uniformity and egg production, but further research will be needed to determine potential differences in nutrient utilization or behavior of the pullets that positively impacted this flock performance. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2020 journal article

Role of long-term supplementation of 25-hydroxyvitamin D3 on egg production and egg quality of laying hen

Poultry Science, 9.

By: C. Chen* , B. Turner, T. Applegate *, G. Litta & W. Kim *

author keywords: 25-hydroxyvitamin D3; laying hen; growth performance; egg production; egg quality
MeSH headings : Animal Feed / analysis; Animals; Calcifediol / pharmacology; Chickens; Diet / veterinary; Dietary Supplements; Egg Shell / drug effects; Eggs / standards; Female; Oviposition / drug effects; Random Allocation
TL;DR: Long-term and early supplementation of 25OHD has positive effects on egg production and egg quality, and the beneficial effects were mainly observed during the early laying stage. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2020 journal article

Role of long-term supplementation of 25-hydroxyvitamin D<inf>3</inf> on laying hen bone 3-dimensional structural development

Poultry Science.

By: C. Chen* , B. Turner, T. Applegate *, G. Litta * & W. Kim *

Contributors: C. Chen* , B. Turner, T. Applegate *, G. Litta * & W. Kim *

author keywords: 25-hydroxyvitamin D-3; 3-dimensional bone structure; pullet; laying hen
MeSH headings : Animals; Bone Density / drug effects; Bone Development / drug effects; Calcifediol / pharmacology; Chickens; Dietary Supplements; Female; Random Allocation
TL;DR: Investigation of the role of long-term supplementation of 25OHD in layer diets on bone 3-dimensional structural development found it could stimulate bone growth and increase bone volume in pullets to provide more space for mineral deposition during the laying period with positive effects on laying hen bone quality. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2020 journal article

The application of micro-CT in egg-laying hen bone analysis: introducing an automated bone separation algorithm

Poultry Science.

By: C. Chen*  & W. Kim *

Contributors: C. Chen*  & W. Kim *

author keywords: micro-CT; laying hen bone; bone separation; 3D analysis
MeSH headings : Algorithms; Animals; Bone and Bones / diagnostic imaging; Chickens / anatomy & histology; Pattern Recognition, Automated / methods; X-Ray Microtomography
TL;DR: An automated segmentation algorithm is described to allow researchers to segment bone compartments without human bias, designed according to the morphology difference of medullary bones compared to trabecular and cortical bones. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2019 journal article

Effects of lysophospholipid on growth performance, carcass yield, intestinal development, and bone quality in broilers

Poultry Science, 98(9), 3902–3913.

By: C. Chen* , B. Jung & W. Kim*

Contributors: C. Chen* , B. Jung & W. Kim*

author keywords: lysophospholipids; growth performance; carcass yield; intestinal development; bone quality
MeSH headings : Animal Feed / analysis; Animals; Bone and Bones / drug effects; Bone and Bones / physiology; Chickens / growth & development; Chickens / physiology; Diet / veterinary; Dietary Supplements / analysis; Dose-Response Relationship, Drug; Intestines / drug effects; Intestines / growth & development; Lysophospholipids / administration & dosage; Lysophospholipids / metabolism; Male; Meat / analysis; Random Allocation
TL;DR: Dairy LPL supplementation promoted growth performance, carcass yield, intestinal development, intestinal health, and bone quality in broilers and significantly increased the total Ca and P deposition and positively affected the bone structure development. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: October 15, 2020

2019 journal article

Isolation and differentiation of mesenchymal stem cells from broiler chicken compact bones

Frontiers in Physiology, 10(JAN).

By: R. Adhikari *, C. Chen* , E. Waters *, F. West * & W. Kim *

Contributors: R. Adhikari *, C. Chen* , E. Waters *, F. West * & W. Kim *

author keywords: mesenchymal stem cells; isolation; broiler; biological characteristics; pluripotency
TL;DR: The results suggest that MSCs isolated from broiler compact bones (cBMSCs) possess similar biological characteristics as MSCS isolated from other chicken tissue sources. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: October 15, 2020

2018 journal article

Effect of antibiotic withdrawal in feed on chicken gut microbial dynamics, immunity, growth performance and prevalence of foodborne pathogens

PLoS ONE, 13(2).

By: S. Kumar *, C. Chen* , N. Indugu *, G. Werlang *, M. Singh *, W. Kim *, H. Thippareddi *

Contributors: S. Kumar *, C. Chen* , N. Indugu *, G. Werlang *, M. Singh *, W. Kim *, H. Thippareddi *

MeSH headings : Animal Feed; Animals; Bacitracin / administration & dosage; Chickens; Cytokines / genetics; Food Microbiology; Gene Expression; Growth; Intestines / immunology; Intestines / microbiology; Microbiota / genetics; RNA, Ribosomal, 16S / genetics; Real-Time Polymerase Chain Reaction
TL;DR: Insight is provided of the impact of AGP supplementation in the feed on gut microbial modulations, bird performance, host immunity and pathogen prevalence that can assist in designing alternative strategies to replace antibiotics in modern poultry production and for food safety. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2018 journal article

Effects of vitamin d and calcium for the prevention of osteoporosis at various stages of life of laying hens-review

International Journal of Poultry Science, 17(9), 405–409.

By: M. Duran, C. Chen*  & W. Kim *

Contributors: M. Duran, C. Chen*  & W. Kim *

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: October 15, 2020

2017 journal article

Fatty Acids Have Different Adipogenic Differentiation Potentials in Stromal Vascular Cells Isolated from Abdominal Fat in Laying Hens

Lipids, 52(6), 513–522.

By: A. Regassa*, M. Suh *, J. Datar*, C. Chen*  & W. Kim *

Contributors: A. Regassa*, M. Suh *, J. Datar*, C. Chen*  & W. Kim *

author keywords: Adipogenesis; Fatty acids; Gene expression; Glycerol-3-phosphate dehydrogenase; Hen stromal vascular cell
MeSH headings : Abdominal Fat / blood supply; Adipocytes / cytology; Adipocytes / metabolism; Adipogenesis; Animals; Blood Vessels / cytology; Blood Vessels / metabolism; Cells, Cultured; Chickens / genetics; Chickens / physiology; Fatty Acids / metabolism; Female; Gene Expression Regulation, Developmental; Stromal Cells / cytology; Stromal Cells / metabolism
TL;DR: Results showed that FA have different potentials to induce adipogenesis, LNA is the most potent among the tested FA, and these potentials can be improved in the presence of CS. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

2012 journal article

Effects of aluminum trichloride on the trace elements and cytokines in the spleen of rats

Food and Chemical Toxicology, 50(8), 2911–2915.

By: Y. Zhu *, X. Li *, C. Chen* , F. Wang, J. Li *, C. Hu*, Y. Li *, L. Miao*

Contributors: Y. Zhu *, X. Li *, C. Chen* , F. Wang, J. Li *, C. Hu*, Y. Li *, L. Miao*

author keywords: Aluminum; Spleen; Trace elements; Cytokines; Rats
MeSH headings : Aluminum Chloride; Aluminum Compounds / pharmacology; Animals; Body Weight / drug effects; Chlorides / pharmacology; Interleukin-2 / metabolism; Male; Rats; Rats, Wistar; Spleen / drug effects; Spleen / metabolism; Trace Elements / metabolism; Tumor Necrosis Factor-alpha / metabolism
TL;DR: The results suggest that AlCl(3) can suppress the growth of spleen, disorder the balance of trace elements and inhibit the immune regulation of cytokines in the spleen. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: October 15, 2020

2011 journal article

Effects of Aluminum on immune functions of cultured splenic T and B lymphocytes in rats

Biological Trace Element Research, 147(1-3), 246–250.

By: Y. She *, N. Wang *, C. Chen* , Y. Zhu *, S. Xia*, C. Hu*, Y. Li *

Contributors: Y. She *, N. Wang *, C. Chen* , Y. Zhu *, S. Xia*, C. Hu*, Y. Li *

author keywords: Aluminum; Immune functions; Splenic lymphocytes; Rats
MeSH headings : Aluminum / pharmacology; Aluminum Chloride; Aluminum Compounds / pharmacology; Animals; B-Lymphocytes / drug effects; B-Lymphocytes / immunology; B-Lymphocytes / metabolism; CD3 Complex / immunology; CD3 Complex / metabolism; CD4-Positive T-Lymphocytes / drug effects; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; CD8-Positive T-Lymphocytes / drug effects; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; Cell Proliferation / drug effects; Cells, Cultured; Chlorides / pharmacology; Dose-Response Relationship, Drug; Interleukin-2 / immunology; Interleukin-2 / metabolism; Interleukin-6 / immunology; Interleukin-6 / metabolism; Lymphocyte Count; Male; Radioimmunoassay; Rats; Rats, Wistar; Spleen / cytology; Spleen / immunology; T-Lymphocytes / drug effects; T-Lymphocytes / immunology; T-Lymphocytes / metabolism; Tumor Necrosis Factor-alpha / immunology; Tumor Necrosis Factor-alpha / metabolism
TL;DR: The results showed that Al exposure can inhibit the immune functions of splenic T and B lymphocytes of rats in vitro, and the levels of IL-2, IL-6, TNF-α, the proportions of CD3+ and CD4+ T lymphocytes, andThe ratio of CD4-/CD8-T lymphocytes were lowered by Al treatments, while the proportion of CD8+ Tymphocytes was increased. (via Semantic Scholar)
Source: ORCID
Added: October 15, 2020

Employment

Updated: August 15th, 2022 09:43

2022 - present

University of Georgia Department of Poultry Science Athens, GA, US
Assistant Professor/Extension Specialist Department of Poultry Science

2020 - present

NC State University Raleigh, NC, US
Project Coordinator/Manager Animal Health and Nutrition Consoritum

2020 - present

North Carolina State University Raleigh, North Carolina, US
Research Assistant Professor Prestage Department of Poultry Science

2019 - 2020

University of Georgia Athens, Georgia, US
Postdoc Department of Poultry Science

2014 - 2018

University of Georgia Athens, GA, US
Graduate assistant Poultry Science department

Education

Updated: May 22nd, 2015 12:34

2014 - present

University of Georgia Athens, GA, US
Poultry Science

2009 - 2014

China Agricultural University Beijing, Beijing, CN
Bachelor Veterinary Medicine

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