@article{zhang_chen_becker_rufo_yang_mai_zhang_gu_wang_ma_et al._2022, title={A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER)}, url={https://doi.org/10.1126/sciadv.ade0640}, DOI={10.1126/sciadv.ade0640}, abstractNote={High-precision isolation of small extracellular vesicles (sEVs) from biofluids is essential toward developing next-generation liquid biopsies and regenerative therapies. However, current methods of sEV separation require specialized equipment and time-consuming protocols and have difficulties producing highly pure subpopulations of sEVs. Here, we present Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER), which allows single-step, rapid (<10 min), high-purity (>96% small exosomes, >80% exomeres) fractionation of sEV subpopulations from biofluids without the need for any sample preprocessing. Particles are iteratively deflected in a size-selective manner via an excitation resonance. This previously unidentified phenomenon generates patterns of virtual, tunable, pillar-like acoustic field in a fluid using surface acoustic waves. Highly precise sEV fractionation without the need for sample preprocessing or complex nanofabrication methods has been demonstrated using ANSWER, showing potential as a powerful tool that will enable more in-depth studies into the complexity, heterogeneity, and functionality of sEV subpopulations.}, journal={Science Advances}, author={Zhang, Jinxin and Chen, Chuyi and Becker, Ryan and Rufo, Joseph and Yang, Shujie and Mai, John and Zhang, Peiran and Gu, Yuyang and Wang, Zeyu and Ma, Zhehan and et al.}, year={2022}, month={Nov} }
 @article{zhang_rufo_chen_xia_tian_zhang_hao_zhong_gu_chakrabarty_et al._2021, title={Acoustoelectronic nanotweezers enable dynamic and large-scale control of nanomaterials}, url={https://doi.org/10.1038/s41467-021-24101-z}, DOI={10.1038/s41467-021-24101-z}, abstractNote={Abstract}, journal={Nature Communications}, author={Zhang, Peiran and Rufo, Joseph and Chen, Chuyi and Xia, Jianping and Tian, Zhenhua and Zhang, Liying and Hao, Nanjing and Zhong, Zhanwei and Gu, Yuyang and Chakrabarty, Krishnendu and et al.}, year={2021}, month={Jun} }
 @article{gu_chen_mao_bachman_becker_rufo_wang_zhang_mai_yang_et al._2021, title={Acoustofluidic centrifuge for nanoparticle enrichment and separation}, volume={7}, url={https://doi.org/10.1126/sciadv.abc0467}, DOI={10.1126/sciadv.abc0467}, abstractNote={Acoustofluidic centrifugation enables the spinning of a fluidic droplet and nanoparticle enrichment and separation.}, number={1}, journal={Science Advances}, publisher={American Association for the Advancement of Science (AAAS)}, author={Gu, Yuyang and Chen, Chuyi and Mao, Zhangming and Bachman, Hunter and Becker, Ryan and Rufo, Joseph and Wang, Zeyu and Zhang, Peiran and Mai, John and Yang, Shujie and et al.}, year={2021}, month={Jan} }
 @article{zhang_chen_su_mai_gu_tian_zhu_zhong_fu_yang_et al._2020, title={Acoustic streaming vortices enable contactless, digital control of droplets}, volume={6}, url={https://doi.org/10.1126/sciadv.aba0606}, DOI={10.1126/sciadv.aba0606}, abstractNote={The switching of acoustic streaming vortices allows the contactless gating and routing of microliter droplets with scalability.}, number={24}, journal={Science Advances}, publisher={American Association for the Advancement of Science (AAAS)}, author={Zhang, Peiran and Chen, Chuyi and Su, Xingyu and Mai, John and Gu, Yuyang and Tian, Zhenhua and Zhu, Haodong and Zhong, Zhanwei and Fu, Hai and Yang, Shujie and et al.}, year={2020}, month={Jun} }
 @article{zhang_yang_chen_hartman_huang_wang_tian_zhang_faulkenberry_meyer_et al._2019, title={Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans}, volume={19}, url={https://doi.org/10.1039/C8LC01012A}, DOI={10.1039/C8LC01012A}, abstractNote={A surface acoustic wave based chip capable of rotating C. elegans in both static and continuous flow in a controllable manner.}, number={6}, journal={Lab on a Chip}, publisher={Royal Society of Chemistry (RSC)}, author={Zhang, Jinxin and Yang, Shujie and Chen, Chuyi and Hartman, Jessica H. and Huang, Po-Hsun and Wang, Lin and Tian, Zhenhua and Zhang, Peiran and Faulkenberry, David and Meyer, Joel N. and et al.}, year={2019}, pages={984–992} }
 @article{tian_yang_huang_wang_zhang_gu_bachman_chen_wu_xie_et al._2019, title={Wave number–spiral acoustic tweezers for dynamic and reconfigurable manipulation of particles and cells}, volume={5}, url={https://doi.org/10.1126/sciadv.aau6062}, DOI={10.1126/sciadv.aau6062}, abstractNote={Acoustic tweezers with frequency multiplexing enable dynamic manipulation of micro-objects using dual-channel excitation.}, number={5}, journal={Science Advances}, publisher={American Association for the Advancement of Science (AAAS)}, author={Tian, Zhenhua and Yang, Shujie and Huang, Po-Hsun and Wang, Zeyu and Zhang, Peiran and Gu, Yuyang and Bachman, Hunter and Chen, Chuyi and Wu, Mengxi and Xie, Yangbo and et al.}, year={2019}, month={May} }