Christopher C. Ladner

Works (1)

Updated: July 5th, 2023 15:39

2015 journal article

Harnessing natural product assembly lines: structure, promiscuity, and engineering

Journal of Industrial Microbiology & Biotechnology, 43(2-3), 371–387.

By: C. Ladner n & G. Williams n 

author keywords: Combinatorial biosynthesis; Synthetic biology; Enzyme engineering; Polyketide synthases; Non-ribosomal peptide synthases
MeSH headings : Biological Products / chemistry; Biological Products / metabolism; Biosynthetic Pathways / genetics; Metabolic Engineering; Peptides / metabolism; Polyketides / metabolism
TL;DR: This review briefly summarizes recent structural advances related to natural product assembly lines, discusses chemical approaches to probing assembly line structures in the absence of traditional biophysical data, and surveys efforts that harness the inherent or engineered promiscuity of assembly lines for the synthesis of non-natural polyketides and non-ribosomal peptide analogues. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.