@article{jeon_ackart_li_jackson_melander_melander_abramovitch_chicco_basaraba_obregon-henao_2019, title={2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain}, volume={9}, DOI={10.1038/s41598-018-38064-7}, journal={SCIENTIFIC REPORTS}, author={Jeon, Albert Byungyun and Ackart, David F. and Li, Wei and Jackson, Mary and Melander, Roberta J. and Melander, Christian and Abramovitch, Robert B. and Chicco, Adam J. and Basaraba, Randall J. and Obregon-Henao, Andres}, year={2019} }
 @article{nguyen_minrovic_melander_melander_2019, title={Identification of Anti-Mycobacterial Biofilm Agents Based on the 2-Aminoimidazole Scaffold}, volume={14}, ISBN={1860-7187}, DOI={10.1002/cmdc.201900033}, number={9}, journal={CHEMMEDCHEM}, author={Nguyen, T. Vu and Minrovic, Bradley M. and Melander, Roberta J. and Melander, Christian}, year={2019}, pages={927–937} }
 @article{martin_melander_brackett_scott_chandler_nguyen_minrovic_harrill_ernst_manoil_et al._2019, title={Small Molecule Potentiation of Gram-Positive Selective Antibiotics against Acinetobacter baumannii}, volume={5}, ISBN={2373-8227}, DOI={10.1021/acsinfecdis.9b00067}, number={7}, journal={ACS INFECTIOUS DISEASES}, author={Martin, Sara E. and Melander, Roberta J. and Brackett, Christopher M. and Scott, Alison J. and Chandler, Courtney E. and Nguyen, Catherine M. and Minrovic, Bradley M. and Harrill, Sarah E. and Ernst, Robert K. and Manoil, Colin and et al.}, year={2019}, month={Jul}, pages={1223–1230} }
 @article{nguyen_peszko_melander_melander_2019, title={Using 2-aminobenzimidazole derivatives to inhibit Mycobacterium smegmatis biofilm formation}, volume={10}, ISBN={2040-2511}, DOI={10.1039/c9md00025a}, number={3}, journal={MEDCHEMCOMM}, author={Nguyen, T. Vu and Peszko, Matthew T. and Melander, Roberta J. and Melander, Christian}, year={2019}, pages={456–459} }
 @article{hubble_hubbard_minrovic_melander_melander_2019, title={Using Small-Molecule Adjuvants to Repurpose Azithromycin for Use against Pseudomonas aeruginosa}, volume={5}, ISBN={2373-8227}, DOI={10.1021/acsinfecdis.8b00288}, number={1}, journal={ACS INFECTIOUS DISEASES}, author={Hubble, Veronica B. and Hubbard, Brittany A. and Minrovic, Bradley M. and Melander, Roberta J. and Melander, Christian}, year={2019}, month={Jan}, pages={141–151} }
 @misc{melander_zurawski_melander_2018, title={Narrow-spectrum antibacterial agents}, volume={9}, DOI={10.1039/c7md00528h}, number={1}, journal={MedChemComm}, author={Melander, R. J. and Zurawski, D. V. and Melander, C.}, year={2018}, pages={12–21} }
 @article{milton_minrovic_harris_kang_jung_lewis_thompson_melander_zeng_melander_et al._2018, title={Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp.}, volume={5}, DOI={10.3389/fmolb.2018.00015}, journal={FRONTIERS IN MOLECULAR BIOSCIENCES}, author={Milton, Morgan E. and Minrovic, Bradley M. and Harris, Danni L. and Kang, Brian and Jung, David and Lewis, Caleb P. and Thompson, Richele J. and Melander, Roberta J. and Zeng, Daina and Melander, Christian and et al.}, year={2018} }
 @article{jeon_obregon-henao_ackart_podell_belardinelli_jackson_nguyen_blackledge_melander_melander_et al._2017, title={2-aminoimidazoles potentiate beta-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing beta-lactamase secretion and increasing cell envelope permeability}, volume={12}, number={7}, journal={PLoS One}, author={Jeon, A. B. and Obregon-Henao, A. and Ackart, D. F. and Podell, B. K. and Belardinelli, J. M. and Jackson, M. and Nguyen, T. V. and Blackledge, M. S. and Melander, R. J. and Melander, C. and et al.}, year={2017} }
 @article{yuen_walper_melde_daniele_stenger_2017, title={Electrolyte-sensing transistor decals enabled by ultrathin microbial nanocellulose}, volume={7}, journal={Scientific Reports}, author={Yuen, J. D. and Walper, S. A. and Melde, B. J. and Daniele, M. A. and Stenger, D. A.}, year={2017} }
 @article{draughn_allen_routh_stone_kirker_boegli_schuchman_linder_baynes_james_et al._2017, title={Evaluation of a 2-aminoimidazole variant as adjuvant treatment for dermal bacterial infections}, volume={11}, journal={Drug Design Development and Therapy}, author={Draughn, G. L. and Allen, C. L. and Routh, P. A. and Stone, M. R. and Kirker, K. R. and Boegli, A. and Schuchman, R. M. and Linder, K. E. and Baynes, R. E. and James, G. and et al.}, year={2017}, pages={153–162} }
 @article{byrne-nash_lucero_osbaugh_melander_melander_feldheim_2017, title={Probing the mechanism of LAL-32, a gold nanoparticle-based antibiotic discovered through small molecule variable ligand display}, volume={28}, DOI={10.1021/acs.bioconjchem.7b00199}, number={7}, journal={Bioconjugate Chemistry}, author={Byrne-Nash, R. and Lucero, D. M. and Osbaugh, N. A. and Melander, R. J. and Melander, C. and Feldheim, D. L.}, year={2017}, pages={1807–1810} }
 @article{barker_martin_chandler_nguyen_harris_goodell_melander_doi_ernst_melander_2017, title={Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria}, volume={25}, DOI={10.1016/j.bmc.2017.08.055}, number={20}, journal={Bioorganic & Medicinal Chemistry}, author={Barker, W. T. and Martin, S. E. and Chandler, C. E. and Nguyen, T. V. and Harris, T. L. and Goodell, C. and Melander, R. J. and Doi, Y. and Ernst, R. K. and Melander, C.}, year={2017}, pages={5749–5753} }
 @article{milton_allen_feldmann_bobay_jung_stephens_melander_theisen_zeng_thompson_et al._2017, title={Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds}, volume={106}, DOI={10.1111/mmi.13759}, number={2}, journal={Molecular Microbiology}, author={Milton, M. E. and Allen, C. L. and Feldmann, E. A. and Bobay, B. G. and Jung, D. K. and Stephens, M. D. and Melander, R. J. and Theisen, K. E. and Zeng, D. and Thompson, R. J. and et al.}, year={2017}, pages={223–235} }
 @article{garcia_blackledge_michalek_su_ptacek_eipers_morrow_lefkowitz_melander_wu_2017, title={Targeting of streptococcus mutans biofilms by a novel small molecule prevents dental caries and preserves the oral microbiome}, volume={96}, DOI={10.1177/0022034517698096}, number={7}, journal={Journal of Dental Research}, author={Garcia, S. S. and Blackledge, M. S. and Michalek, S. and Su, L. and Ptacek, T. and Eipers, P. and Morrow, C. and Lefkowitz, E. J. and Melander, C. and Wu, H.}, year={2017}, pages={807–814} }
 @article{melander_melander_2017, title={The challenge of overcoming antibiotic resistance: An adjuvant approach?}, volume={3}, DOI={10.1021/acsinfecdis.7b00071}, number={8}, journal={ACS Infectious Diseases}, author={Melander, R. J. and Melander, C.}, year={2017}, pages={559–563} }
 @article{nguyen_blackledge_lindsey_minrovic_ackart_jeon_obregon-henao_melander_basaraba_melander_2017, title={The discovery of 2-aminobenzimidazoles that sensitize mycobacterium smegmatis and m. tuberculosis to beta-lactam antibiotics in a pattern distinct from beta-lactamase inhibitors}, volume={56}, DOI={10.1002/anie.201612006}, number={14}, journal={Angewandte Chemie [International Edition in English]}, author={Nguyen, T. V. and Blackledge, M. S. and Lindsey, E. A. and Minrovic, B. M. and Ackart, D. F. and Jeon, A. B. and Obregon-Henao, A. and Melander, R. J. and Basaraba, R. J. and Melander, C.}, year={2017}, pages={3940–3944} }
 @article{stephens_yodsanit_melander_2016, title={Evaluation of ethyl N-(2-phenethyl) carbamate analogues as biofilm inhibitors of methicillin resistant Staphylococcus aureus}, volume={14}, DOI={10.1039/c6ob00706f}, number={28}, journal={Organic & Biomolecular Chemistry}, author={Stephens, M. D. and Yodsanit, N. and Melander, C.}, year={2016}, pages={6853–6856} }
 @article{melander_liu_stephens_bewley_melander_2016, title={Marine sponge alkaloids as a source of anti-bacterial adjuvants}, volume={26}, DOI={10.1016/j.bmcl.2016.11.018}, number={24}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Melander, R. J. and Liu, H. B. and Stephens, M. D. and Bewley, C. A. and Melander, C.}, year={2016}, pages={5863–5866} }
 @article{stephens_hubble_ernst_hoek_melander_cavanagh_melander_2016, title={Potentiation of Francisella resistance to conventional antibiotics through small molecule adjuvants}, volume={7}, DOI={10.1039/c5md00353a}, number={1}, journal={MedChemComm}, author={Stephens, M. D. and Hubble, V. B. and Ernst, R. K. and Hoek, M. L. and Melander, R. J. and Cavanagh, J. and Melander, C.}, year={2016}, pages={128–131} }
 @article{stephens_yodsanit_melander_2016, title={Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida}, volume={7}, DOI={10.1039/c6md00365f}, number={10}, journal={MedChemComm}, author={Stephens, M. D. and Yodsanit, N. and Melander, C.}, year={2016}, pages={1952–1956} }
 @article{brackett_furlani_anderson_krishnamurthy_melander_moskowitz_ernst_melander_2016, title={Second generation modifiers of colistin resistance show enhanced activity and lower inherent toxicity}, volume={72}, DOI={10.1016/j.tet.2015.09.019}, number={25}, journal={Tetrahedron}, author={Brackett, C. M. and Furlani, R. E. and Anderson, R. G. and Krishnamurthy, A. and Melander, R. J. and Moskowitz, S. M. and Ernst, R. K. and Melander, C.}, year={2016}, pages={3549–3553} }
 @article{pan_fan_wu_melander_liu_2015, title={A new small molecule inhibits Streptococcus mutans biofilms invitro and in vivo}, volume={119}, DOI={10.1111/jam.12940}, number={5}, journal={Journal of Applied Microbiology}, author={Pan, W. and Fan, M. and Wu, H. and Melander, C. and Liu, C.}, year={2015}, pages={1403–1411} }
 @article{wahome_beauchesne_pedone_cavanagh_melander_zimba_moeller_2015, title={Augmenting anti-cancer natural products with a small molecule adjuvant}, volume={13}, number={1}, journal={Marine Drugs}, author={Wahome, P. G. and Beauchesne, K. R. and Pedone, A. C. and Cavanagh, J. and Melander, C. and Zimba, P. and Moeller, P. D. R.}, year={2015}, pages={65–75} }
 @article{melander_melander_2015, title={From worms to targeting virulence factors}, volume={22}, DOI={10.1016/j.chembiol.2015.04.005}, number={4}, journal={Chemistry & Biology}, author={Melander, R. J. and Melander, C.}, year={2015}, pages={436–437} }
 @article{garrido_simpson_dahl_bresee_whitehead_lindsey_harris_smith_carter_feldheim_et al._2015, title={Gold nanoparticles to improve HIV drug delivery}, volume={7}, DOI={10.4155/fmc.15.57}, number={9}, journal={Future medicinal chemistry}, author={Garrido, C. and Simpson, C. A. and Dahl, N. P. and Bresee, J. and Whitehead, D. C. and Lindsey, E. A. and Harris, T. L. and Smith, C. A. and Carter, C. J. and Feldheim, D. L. and et al.}, year={2015}, pages={1097–1107} }
 @article{richardson_furlani_podell_ackart_haugen_melander_melander_basaraba_2015, title={Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives}, volume={56}, DOI={10.1016/j.tetlet.2015.01.122}, number={23}, journal={Tetrahedron Letters}, author={Richardson, M. A. and Furlani, R. E. and Podell, B. K. and Ackart, D. F. and Haugen, J. D. and Melander, R. J. and Melander, C. and Basaraba, R. J.}, year={2015}, pages={3406–3409} }
 @article{melander_melander_2015, title={Innovative strategies for combating biofilm-based infections}, volume={831}, journal={Biofilm-based healthcare-associated infections, vol ii}, author={Melander, R. J. and Melander, C.}, year={2015}, pages={69–91} }
 @article{stowe_thompson_peng_su_blackledge_draughn_coe_johannes_lapham_mackenzie_et al._2015, title={Membrane-permeabilizing activity of reverse-amide 2-aminoimidazole antibiofilm agents against Acinetobacter baumannii}, volume={12}, DOI={10.2174/1567201811666140924125740}, number={2}, journal={Current Drug Delivery}, author={Stowe, S. D. and Thompson, R. J. and Peng, L. L. and Su, Z. M. and Blackledge, M. S. and Draughn, G. L. and Coe, W. H. and Johannes, E. and Lapham, V. K. and Mackenzie, J. and et al.}, year={2015}, pages={223–230} }
 @article{furlani_richardson_podell_ackart_haugen_melander_basaraba_melander_2015, title={Second generation 2-aminoimidazole based advanced glycation end product inhibitors and breakers}, volume={25}, DOI={10.1016/j.bmcl.2015.06.080}, number={21}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Furlani, R. E. and Richardson, M. A. and Podell, B. K. and Ackart, D. F. and Haugen, J. D. and Melander, R. J. and Basaraba, R. J. and Melander, C.}, year={2015}, pages={4820–4823} }
 @article{melander_minvielle_melander_2014, title={Controlling bacterial behavior with indole-containing natural products and derivatives}, volume={70}, DOI={10.1016/j.tet.2014.05.089}, number={37}, journal={Tetrahedron}, author={Melander, R. J. and Minvielle, M. J. and Melander, C.}, year={2014}, pages={6363–6372} }
 @article{ackart_hascall-dove_caceres_kirk_podell_melander_orme_leid_nick_basaraba_2014, title={Expression of antimicrobial drug tolerance by attached communities of Mycobacterium tuberculosis}, volume={70}, DOI={10.1111/2049-632x.12144}, number={3}, journal={Pathogens and Disease}, author={Ackart, D. F. and Hascall-Dove, L. and Caceres, S. M. and Kirk, N. M. and Podell, B. K. and Melander, C. and Orme, I. M. and Leid, J. G. and Nick, J. A. and Basaraba, R. J.}, year={2014}, pages={359–369} }
 @article{bresee_bond_worthington_smith_gifford_simpson_carter_wang_hartman_osbaugh_et al._2014, title={Nanoscale structure-activity relationships, mode of action, and biocompatibility of gold nanoparticle antibiotics}, volume={136}, DOI={10.1021/ja408505n}, number={14}, journal={Journal of the American Chemical Society}, author={Bresee, J. and Bond, C. M. and Worthington, R. J. and Smith, C. A. and Gifford, J. C. and Simpson, C. A. and Carter, C. J. and Wang, G. K. and Hartman, J. and Osbaugh, N. A. and et al.}, year={2014}, pages={5295–5300} }
 @article{ackart_lindsey_podell_melander_basaraba_melander_2014, title={Reversal of Mycobacterium tuberculosis phenotypic drug resistance by 2-aminoimidazole- based small molecules}, volume={70}, DOI={10.1111/2049-632x.12143}, number={3}, journal={Pathogens and Disease}, author={Ackart, D. F. and Lindsey, E. A. and Podell, B. K. and Melander, R. J. and Basaraba, R. J. and Melander, C.}, year={2014}, pages={370–378} }
 @article{harris_worthington_hittle_zurawski_ernst_melander_2014, title={Small molecule downregulation of PmrAB reverses lipid A modification and breaks colistin resistance}, volume={9}, DOI={10.1021/cb400490k}, number={1}, journal={ACS Chemical Biology}, author={Harris, T. L. and Worthington, R. J. and Hittle, L. E. and Zurawski, D. V. and Ernst, R. K. and Melander, C.}, year={2014}, pages={122–127} }
 @article{brackett_melander_an_krishnamurthy_thompson_cavanagh_melander_2014, title={Small-molecule suppression of beta-lactam resistance in multidrug-resistant gram-negative pathogens}, volume={57}, DOI={10.1021/jm501050e}, number={17}, journal={Journal of Medicinal Chemistry}, author={Brackett, C. M. and Melander, R. J. and An, I. H. and Krishnamurthy, A. and Thompson, R. J. and Cavanagh, J. and Melander, C.}, year={2014}, pages={7450–7458} }
 @article{gifford_bresee_carter_wang_melander_melander_feldheim_2014, title={Thiol-modified gold nanoparticles for the inhibition of Mycobacterium smegmatis}, volume={50}, DOI={10.1039/c4cc06236a}, number={100}, journal={Chemical Communications}, author={Gifford, J. C. and Bresee, J. and Carter, C. J. and Wang, G. K. and Melander, R. J. and Melander, C. and Feldheim, D. L.}, year={2014}, pages={15860–15863} }
 @article{furlani_yeagley_melander_2013, title={A flexible approach to 1,4-di-substituted 2-aminoimidazoles that inhibit and disperse biofilms and potentiate the effects of beta-lactams against multi-drug resistant bacteria}, volume={62}, DOI={10.1016/j.ejmech.2012.12.005}, journal={European Journal of Medicinal Chemistry}, author={Furlani, R. E. and Yeagley, A. A. and Melander, C.}, year={2013}, pages={59–70} }
 @article{blackledge_worthington_melander_2013, title={Biologically inspired strategies for combating bacterial biofilms}, volume={13}, DOI={10.1016/j.coph.2013.07.004}, number={5}, journal={Current Opinion in Pharmacology}, author={Blackledge, M. S. and Worthington, R. J. and Melander, C.}, year={2013}, pages={699–706} }
 @misc{worthington_melander_2013, title={Combination approaches to combat multidrug-resistant bacteria}, volume={31}, DOI={10.1016/j.tibtech.2012.12.006}, number={3}, journal={Trends in Biotechnology}, author={Worthington, R. J. and Melander, C.}, year={2013}, pages={177–184} }
 @article{minvielle_eguren_melander_2013, title={Highly active modulators of indole signaling alter pathogenic behaviors in gram-negative and gram-positive bacteria}, volume={19}, DOI={10.1002/chem.201303510}, number={51}, journal={Chemistry (Weinheim An Der Bergstrasse, Germany)}, author={Minvielle, M. J. and Eguren, K. and Melander, C.}, year={2013}, pages={17595–17602} }
 @article{minvielle_bunders_melander_2013, title={Indole-triazole conjugates are selective inhibitors and inducers of bacterial biofilms}, volume={4}, DOI={10.1039/c3md00064h}, number={6}, journal={MedChemComm}, author={Minvielle, M. J. and Bunders, C. A. and Melander, C.}, year={2013}, pages={916–919} }
 @article{yeagley_su_mccullough_worthington_melander_2013, title={N-Substituted 2-aminoimidazole inhibitors of MRSA biofilm formation accessed through direct 1,3-bis(tert-butoxycarbonyl)guanidine cyclization}, volume={11}, DOI={10.1039/c2ob26469b}, number={1}, journal={Organic & Biomolecular Chemistry}, author={Yeagley, A. A. and Su, Z. M. and McCullough, K. D. and Worthington, R. J. and Melander, C.}, year={2013}, pages={130–137} }
 @article{worthington_melander_2013, title={Overcoming resistance to beta-lactam antibiotics}, volume={78}, DOI={10.1021/jo400236f}, number={9}, journal={Journal of Organic Chemistry}, author={Worthington, R. J. and Melander, C.}, year={2013}, pages={4207–4213} }
 @article{blackledge_melander_2013, title={Programmable DNA-binding small molecules}, volume={21}, DOI={10.1016/j.bmc.2013.04.023}, number={20}, journal={Bioorganic & Medicinal Chemistry}, author={Blackledge, M. S. and Melander, C.}, year={2013}, pages={6101–6114} }
 @misc{worthington_blackledge_melander_2013, title={Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence}, volume={5}, DOI={10.4155/fmc.13.58}, number={11}, journal={Future medicinal chemistry}, author={Worthington, R. J. and Blackledge, M. S. and Melander, C.}, year={2013}, pages={1265–1284} }
 @article{lindsey_worthington_alcaraz_melander_2012, title={2-Aminopyrimidine as a novel scaffold for biofilm modulation}, volume={10}, number={13}, journal={Organic & Biomolecular Chemistry}, author={Lindsey, E. A. and Worthington, R. J. and Alcaraz, C. and Melander, C.}, year={2012}, pages={2552–2561} }
 @article{su_peng_melander_2012, title={A modular approach to the synthesis of 1,4,5-substituted-2-aminoimidazoles}, volume={53}, DOI={10.1016/j.tetlet.2011.12.090}, number={10}, journal={Tetrahedron Letters}, author={Su, Z. M. and Peng, L. L. and Melander, C.}, year={2012}, pages={1204–1206} }
 @article{worthington_melander_2012, title={Deconvoluting interspecies bacterial communication}, volume={51}, DOI={10.1002/anie.201202440}, number={26}, journal={Angewandte Chemie [International Edition in English]}, author={Worthington, R. J. and Melander, C.}, year={2012}, pages={6314–6315} }
 @article{stowe_tucker_thompson_piper_richards_rogers_mathies_melander_cavanagh_2012, title={Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems}, volume={35}, DOI={10.3109/01480545.2011.614620}, number={3}, journal={Drug and Chemical Toxicology}, author={Stowe, S. D. and Tucker, A. T. and Thompson, R. and Piper, A. and Richards, J. J. and Rogers, S. A. and Mathies, L. D. and Melander, C. and Cavanagh, J.}, year={2012}, pages={310–315} }
 @article{worthington_rogers_huigens_melander_ritchie_2012, title={Foliar-applied small molecule that suppresses biofilm formation and enhances control of copper-resistant Xanthomonas euvesicatoria on pepper}, volume={96}, DOI={10.1094/pdis-02-12-0190-re}, number={11}, journal={Plant Disease}, author={Worthington, R. J. and Rogers, S. A. and Huigens, R. W. and Melander, C. and Ritchie, D. F.}, year={2012}, pages={1638–1644} }
 @article{olson_bobay_melander_cavanagh_2012, title={H-1, C-13, and N-15 resonance assignments and secondary structure prediction of the full-length transition state regulator AbrB from Bacillus anthracis}, volume={6}, DOI={10.1007/s12104-011-9333-2}, number={1}, journal={Biomolecular NMR Assignments}, author={Olson, A. L. and Bobay, B. G. and Melander, C. and Cavanagh, J.}, year={2012}, pages={95–98} }
 @article{thompson_bobay_stowe_olson_peng_su_actis_melander_cavanagh_2012, title={Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-aminoimidazole-based antibiofilm agent}, volume={51}, DOI={10.1021/bi3015289}, number={49}, journal={Biochemistry}, author={Thompson, R. J. and Bobay, B. G. and Stowe, S. D. and Olson, A. L. and Peng, L. L. and Su, Z. M. and Actis, L. A. and Melander, C. and Cavanagh, J.}, year={2012}, pages={9776–9778} }
 @article{melander_margolis_2012, title={Medicinal chemistry: Forcing an enemy into the open}, volume={4}, number={9}, journal={Nature Chemistry}, author={Melander, C. and Margolis, D. M.}, year={2012}, pages={692–693} }
 @article{harris_worthington_melander_2012, title={Potent small-molecule suppression of oxacillin resistance in methicillin-resistant Staphylococcus aureus}, volume={51}, DOI={10.1002/anie.201206911}, number={45}, journal={Angewandte Chemie [International Edition in English]}, author={Harris, T. L. and Worthington, R. J. and Melander, C.}, year={2012}, pages={11254–11257} }
 @article{worthington_richards_melander_2012, title={Small molecule control of bacterial biofilms}, volume={10}, number={37}, journal={Organic & Biomolecular Chemistry}, author={Worthington, R. J. and Richards, J. J. and Melander, C.}, year={2012}, pages={7457–7474} }
 @article{worthington_bunders_reed_melander_2012, title={Small molecule suppression of carbapenem resistance in NDM-1 producing Klebsiella pneumoniae}, volume={3}, DOI={10.1021/ml200290p}, number={5}, journal={ACS Medicinal Chemistry Letters}, author={Worthington, R. J. and Bunders, C. A. and Reed, C. S. and Melander, C.}, year={2012}, pages={357–361} }
 @article{budhathoki-uprety_peng_melander_novak_2012, title={Synthesis of guanidinium functionalized polycarbodiimides and their antibacterial activities}, volume={1}, DOI={10.1021/mz200116k}, number={3}, journal={ACS Macro Letters}, author={Budhathoki-Uprety, J. and Peng, L. and Melander, C. and Novak, B. M.}, year={2012}, pages={370–374} }
 @article{harris_worthington_melander_2011, title={A facile synthesis of 1,5-disubstituted-2-aminoimidazoles: Antibiotic activity of a first generation library}, volume={21}, DOI={10.1016/j.bmcl.2011.05.123}, number={15}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Harris, T. L. and Worthington, R. J. and Melander, C.}, year={2011}, pages={4516–4519} }
 @article{liu_worthington_melander_wu_2011, title={A new small molecule specifically inhibits the cariogenic bacterium streptococcus mutans in multispecies biofilms}, volume={55}, DOI={10.1128/aac.01496-10}, number={6}, journal={Antimicrobial Agents and Chemotherapy}, author={Liu, C. and Worthington, R. J. and Melander, C. and Wu, H.}, year={2011}, pages={2679–2687} }
 @misc{stowe_richards_tucker_thompson_melander_cavanagh_2011, title={Anti-biofilm compounds derived from marine sponges}, volume={9}, number={10}, journal={Marine Drugs}, author={Stowe, S. D. and Richards, J. J. and Tucker, A. T. and Thompson, R. and Melander, C. and Cavanagh, J.}, year={2011}, pages={2010–2035} }
 @article{su_peng_worthington_melander_2011, title={Evaluation of 4,5-disubstituted-2-aminoimidazole-triazole conjugates for antibiofilm/antibiotic resensitization activity against MRSA and Acinetobacter baumannii}, volume={6}, DOI={10.1002/cmdc.201100316}, number={12}, journal={Chemmedchem}, author={Su, Z. M. and Peng, L. L. and Worthington, R. J. and Melander, C.}, year={2011}, pages={2243–2251} }
 @article{bunders_cavanagh_melander_2011, title={Flustramine inspired synthesis and biological evaluation of pyrroloindoline triazole amides as novel inhibitors of bacterial biofilms}, volume={9}, DOI={10.1039/c1ob05605k}, number={15}, journal={Organic & Biomolecular Chemistry}, author={Bunders, C. and Cavanagh, J. and Melander, C.}, year={2011}, pages={5476–5481} }
 @article{bresee_maier_boncella_melander_feldheim_2011, title={Growth inhibition of Staphylococcus aureus by mixed monolayer gold nanoparticles}, volume={7}, DOI={10.1002/smll.201100420}, number={14}, journal={Small (Weinheim An Der Bergstrasse, Germany)}, author={Bresee, J. and Maier, K. E. and Boncella, A. E. and Melander, C. and Feldheim, D. L.}, year={2011}, pages={2027–2031} }
 @article{peng_desousa_su_novak_nevzorov_garland_melander_2011, title={Inhibition of Acinetobacter baumannii biofilm formation on a methacrylate polymer containing a 2-aminoimidazole subunit}, volume={47}, number={17}, journal={Chemical Communications (Cambridge, England)}, author={Peng, L. L. and DeSousa, J. and Su, Z. M. and Novak, B. M. and Nevzorov, A. A. and Garland, E. R. and Melander, C.}, year={2011}, pages={4896–4898} }
 @article{bunders_minvielle_worthington_ortiz_cavanagh_melander_2011, title={Intercepting bacterial indole signaling with flustramine derivatives}, volume={133}, DOI={10.1021/ja209836z}, number={50}, journal={Journal of the American Chemical Society}, author={Bunders, C. A. and Minvielle, M. J. and Worthington, R. J. and Ortiz, M. and Cavanagh, J. and Melander, C.}, year={2011}, pages={20160–20163} }
 @article{rogers_lindsey_whitehead_mullikin_melander_2011, title={Synthesis and biological evaluation of 2-aminoimidazole/carbamate hybrid anti-biofilm and anti-microbial agents}, volume={21}, DOI={10.1016/j.bmcl.2010.12.057}, number={4}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Rogers, S. A. and Lindsey, E. A. and Whitehead, D. C. and Mullikin, T. and Melander, C.}, year={2011}, pages={1257–1260} }
 @article{su_rogers_mccall_smith_ravishankar_mullikin_melander_2010, title={A nitroenolate approach to the synthesis of 4,5-disubstituted-2-aminoimidazoles. Pilot library assembly and screening for antibiotic and antibiofilm activity}, volume={8}, number={12}, journal={Organic & Biomolecular Chemistry}, author={Su, Z. M. and Rogers, S. A. and McCall, W. S. and Smith, A. C. and Ravishankar, S. and Mullikin, T. and Melander, C.}, year={2010}, pages={2814–2822} }
 @article{heinecke_melander_2010, title={Analysis of kinamycin D-mediated DNA cleavage}, volume={51}, DOI={10.1016/j.tetlet.2009.12.142}, number={11}, journal={Tetrahedron Letters}, author={Heinecke, C. L. and Melander, C.}, year={2010}, pages={1455–1458} }
 @article{rogers_bero_melander_2010, title={Chemical synthesis and biological screening of 2-aminoimidazole-based bacterial and fungal antibiofilm agents}, volume={11}, DOI={10.1002/cbic.200900617}, number={3}, journal={Chembiochem}, author={Rogers, S. A. and Bero, J. D. and Melander, C.}, year={2010}, pages={396–410} }
 @article{bresee_maier_melander_feldheim_2010, title={Identification of antibiotics using small molecule variable ligand display on gold nanoparticles}, volume={46}, number={40}, journal={Chemical Communications (Cambridge, England)}, author={Bresee, J. and Maier, K. E. and Melander, C. and Feldheim, D. L.}, year={2010}, pages={7516–7518} }
 @article{bunders_richards_melander_2010, title={Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteria}, volume={20}, DOI={10.1016/j.bmcl.2010.04.042}, number={12}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Bunders, C. A. and Richards, J. J. and Melander, C.}, year={2010}, pages={3797–3800} }
 @article{reed_huigens_rogers_melander_2010, title={Modulating the development of E. coli biofilms with 2-aminoimidazoles}, volume={20}, DOI={10.1016/j.bmcl.2010.08.075}, number={21}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Reed, C. S. and Huigens, R. W. and Rogers, S. A. and Melander, C.}, year={2010}, pages={6310–6312} }
 @article{rogers_huigens_cavanagh_melander_2010, title={Synergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agents}, volume={54}, DOI={10.1128/aac.01418-09}, number={5}, journal={Antimicrobial Agents and Chemotherapy}, author={Rogers, S. A. and Huigens, R. W. and Cavanagh, J. and Melander, C.}, year={2010}, pages={2112–2118} }
 @article{rogers_whitehead_mullikin_melander_2010, title={Synthesis and bacterial biofilm inhibition studies of ethyl N-(2-phenethyl) carbamate derivatives}, volume={8}, number={17}, journal={Organic & Biomolecular Chemistry}, author={Rogers, S. A. and Whitehead, D. C. and Mullikin, T. and Melander, C.}, year={2010}, pages={3857–3859} }
 @article{huigens_reyes_reed_bunders_rogers_steinhauer_melander_2010, title={The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii}, volume={18}, DOI={10.1016/j.bmc.2009.12.003}, number={2}, journal={Bioorganic & Medicinal Chemistry}, author={Huigens, R. W. and Reyes, S. and Reed, C. S. and Bunders, C. and Rogers, S. A. and Steinhauer, A. T. and Melander, C.}, year={2010}, pages={663–674} }
 @article{rogers_huigens_melander_2009, title={A 2-aminobenzimidazole that inhibits and disperses gram-positive biofilms through a zinc-dependent mechanism}, volume={131}, DOI={10.1021/ja9024676}, number={29}, journal={Journal of the American Chemical Society}, author={Rogers, S. A. and Huigens, R. W. and Melander, C.}, year={2009}, pages={9868-} }
 @article{richards_reyes_stowe_tucker_ballard_mathies_cavanagh_melander_2009, title={Amide isosteres of oroidin: Assessment of antibiofilm activity and C. elegans Toxicity}, volume={52}, DOI={10.1021/jm900378s}, number={15}, journal={Journal of Medicinal Chemistry}, author={Richards, J. J. and Reyes, S. and Stowe, S. D. and Tucker, A. T. and Ballard, T. E. and Mathies, L. D. and Cavanagh, J. and Melander, C.}, year={2009}, pages={4582–4585} }
 @article{ballard_richards_aquino_reed_melander_2009, title={Antibiofilm activity of a diverse oroidin library generated through reductive acylation}, volume={74}, DOI={10.1021/jo802260t}, number={4}, journal={Journal of Organic Chemistry}, author={Ballard, T. E. and Richards, J. J. and Aquino, A. and Reed, C. S. and Melander, C.}, year={2009}, pages={1755–1758} }
 @misc{richards_melander_2009, title={Controlling bacterial biofilms}, volume={10}, DOI={10.1002/cbic.200900317}, number={14}, journal={Chembiochem}, author={Richards, J. J. and Melander, C.}, year={2009}, pages={2287–2294} }
 @article{melander_moeller_ballard_richards_huigens_cavanagh_2009, title={Evaluation of dihydrooroidin as an antifouling additive in marine paint}, volume={63}, DOI={10.1016/j.ibiod.2008.08.009}, number={4}, journal={International Biodeterioration & Biodegradation}, author={Melander, C. and Moeller, P. D. R. and Ballard, T. E. and Richards, J. J. and Huigens, R. W. and Cavanagh, J.}, year={2009}, pages={529–532} }
 @article{huigens_rogers_steinhauer_melander_2009, title={Inhibition of Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation with a class of TAGE-triazole conjugates}, volume={7}, DOI={10.1039/b817926c}, number={4}, journal={Organic & Biomolecular Chemistry}, author={Huigens, R. W. and Rogers, S. A. and Steinhauer, A. T. and Melander, C.}, year={2009}, pages={794–802} }
 @article{rogers_krayer_lindsey_melander_2009, title={Tandem dispersion and killing of bacteria from a biofilm}, volume={7}, DOI={10.1039/b817923a}, number={3}, journal={Organic & Biomolecular Chemistry}, author={Rogers, S. A. and Krayer, M. and Lindsey, J. S. and Melander, C.}, year={2009}, pages={603–606} }
 @article{rogers_melander_2008, title={Construction and screening of a 2-aminoimidazole library identifies a small molecule capable of inhibiting and dispersing bacterial biofilms across order, class, and phylum}, volume={47}, DOI={10.1002/anie.200800862}, number={28}, journal={Angewandte Chemie [International Edition in English]}, author={Rogers, S. A. and Melander, C.}, year={2008}, pages={5229–5231} }
 @article{huigens_ma_gambino_moeller_basso_cavanagh_wozniak_melander_2008, title={Control of bacterial biofilms with marine alkaloid derivatives}, volume={4}, DOI={10.1039/b719989a}, number={6}, journal={Molecular BioSystems}, author={Huigens, R. W. and Ma, L. Y. and Gambino, C. and Moeller, P. D. R. and Basso, A. and Cavanagh, J. and Wozniak, D. J. and Melander, C.}, year={2008}, pages={614–621} }
 @article{richards_reed_melander_2008, title={Effects of N-pyrrole substitution on the anti-biofilm activities of oroidin derivatives against Acinetobacter baumannii}, volume={18}, DOI={10.1016/j.bmcl.2008.06.089}, number={15}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Richards, J. J. and Reed, C. S. and Melander, C.}, year={2008}, pages={4325–4327} }
 @article{richards_ballard_melander_2008, title={Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues}, volume={6}, DOI={10.1039/b719082d}, number={8}, journal={Organic & Biomolecular Chemistry}, author={Richards, J. J. and Ballard, T. E. and Melander, C.}, year={2008}, pages={1356–1363} }
 @article{richards_huigens_ballard_basso_cavanagh_melander_2008, title={Inhibition and dispersion of proteobacterial biofilms}, number={14}, journal={Chemical Communications (Cambridge, England)}, author={Richards, J. J. and Huigens, R. W. and Ballard, T. E. and Basso, A. and Cavanagh, J. and Melander, C.}, year={2008}, pages={1698–1700} }
 @article{bowman_ballard_ackerson_feldheim_margolis_melander_2008, title={Inhibition of HIV fusion with multivalent gold nanoparticles}, volume={130}, DOI={10.1021/ja710321g}, number={22}, journal={Journal of the American Chemical Society}, author={Bowman, M. C. and Ballard, T. E. and Ackerson, C. J. and Feldheim, D. L. and Margolis, D. M. and Melander, C.}, year={2008}, pages={6896-} }
 @article{ballard_melander_2008, title={Kinamycin-mediated DNA cleavage under biomimetic conditions}, volume={49}, DOI={10.1016/j.tetlet.2008.03.019}, number={19}, journal={Tetrahedron Letters}, author={Ballard, T. E. and Melander, C.}, year={2008}, pages={3157–3161} }
 @article{ballard_richards_wolfe_melander_2008, title={Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: A structure-activity relationship study}, volume={14}, DOI={10.1002/chem.200801419}, number={34}, journal={Chemistry (Weinheim An Der Bergstrasse, Germany)}, author={Ballard, T. E. and Richards, J. J. and Wolfe, A. L. and Melander, C.}, year={2008}, pages={10745–10761} }
 @article{richards_ballard_huigens_melander_2008, title={Synthesis and screening of an oroidin library against Pseudomonas aeruginosa biofilms}, volume={9}, DOI={10.1002/cbic.200700774}, number={8}, journal={Chembiochem}, author={Richards, J. J. and Ballard, T. E. and Huigens, R. W. and Melander, C.}, year={2008}, pages={1267–1279} }
 @article{richards_melander_2008, title={Synthesis of a 2-aminoimidazole library for antibiofilm screening utilizing the Sonogashira reaction}, volume={73}, DOI={10.1021/jo800618q}, number={13}, journal={Journal of Organic Chemistry}, author={Richards, J. J. and Melander, C.}, year={2008}, pages={5191–5193} }
 @article{burns_bobay_basso_cavanagh_melander_2008, title={Targeting RNA with cysteine-constrained peptides}, volume={18}, DOI={10.1016/j.bmcl.2007.11.096}, number={2}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Burns, V. A. and Bobay, B. G. and Basso, A. and Cavanagh, J. and Melander, C.}, year={2008}, pages={565–567} }
 @article{huigens_richards_parise_ballard_zeng_deora_melander_2007, title={Inhibition of Pseudomonas aeruginosa biofilm formation with bromoageliferin analogues}, volume={129}, number={22}, journal={Journal of the American Chemical Society}, author={Huigens, R. W. and Richards, J. J. and Parise, G. and Ballard, T. E. and Zeng, W. and Deora, R. and Melander, C.}, year={2007}, pages={6966-} }
 @article{zeng_ballard_tkachenko_burns_feldheim_melander_2006, title={Mimicking the biological activity of diazobenzo[b]fluorene natural products with electronically tuned diazofluorene analogs}, volume={16}, DOI={10.1016/j.bmcl.2006.07.024}, number={19}, journal={Bioorganic & Medicinal Chemistry Letters}, author={Zeng, W. and Ballard, T. E. and Tkachenko, A. G. and Burns, V. A. and Feldheim, D. L. and Melander, C.}, year={2006}, pages={5148–5151} }
 @article{zeng_ballard_melander_2006, title={Tuning the oxidation properties of vanadium(V) through ligand stoichiometry}, volume={47}, DOI={10.1016/j.tetlet.2006.06.051}, number={33}, journal={Tetrahedron Letters}, author={Zeng, W. and Ballard, T. E. and Melander, C.}, year={2006}, pages={5923–5926} }