@article{harlow_griesgraber_seman_shuping_sommer_griffith_hileman_nestor_2022, title={The impact of undernutrition on KNDy (kisspeptin/neurokinin B/dynorphin) neurons in female lambs}, volume={5}, DOI={10.1111/jne.13135}, journal={JOURNAL OF NEUROENDOCRINOLOGY}, publisher={Wiley}, author={Harlow, KaLynn and Griesgraber, Max J. and Seman, Andrew D. and Shuping, Sydney L. and Sommer, Jeffrey R. and Griffith, Emily H. and Hileman, Stanley M. and Nestor, Casey C.}, year={2022}, month={May} }
 @article{merkley_shuping_sommer_nestor_2021, title={Evidence That Agouti-Related Peptide May Directly Regulate Kisspeptin Neurons in Male Sheep}, volume={11}, ISBN={2218-1989}, DOI={10.3390/metabol1030138}, number={3}, journal={METABOLITES}, author={Merkley, Christina M. and Shuping, Sydney L. and Sommer, Jeffrey R. and Nestor, Casey C.}, year={2021}, month={Mar} }
 @article{harlow_renwick_shuping_sommer_lents_knauer_nestor_2021, title={Evidence that pubertal status impacts kisspeptin/neurokinin B/dynorphin neurons in the gilt(dagger)}, volume={12}, DOI={10.1093/biolre/ioab189}, journal={BIOLOGY OF REPRODUCTION}, author={Harlow, KaLynn and Renwick, Allison N. and Shuping, Sydney L. and Sommer, Jeffrey R. and Lents, Clay A. and Knauer, Mark T. and Nestor, Casey C.}, year={2021}, month={Dec} }
 @article{aerts_harlow_griesgraber_bowdridge_hardy_nestor_hileman_2021, title={Kisspeptin, Neurokinin B, and Dynorphin Expression during Pubertal Development in Female Sheep}, volume={10}, DOI={10.3390/biology10100988}, journal={BIOLOGY-BASEL}, author={Aerts, Eliana G. and Harlow, KaLynn and Griesgraber, Max J. and Bowdridge, Elizabeth C. and Hardy, Steven L. and Nestor, Casey C. and Hileman, Stanley M.}, year={2021}, month={Oct} }
 @article{harlow_renwick_shuping_sommer_knauer_nestor_2020, title={Effects of genetic selection for early puberty on the hypothalamic-pituitary-ovarian axis in gilts}, volume={98}, ISBN={1525-3163}, DOI={10.1093/jas/skaa054.368}, journal={JOURNAL OF ANIMAL SCIENCE}, author={Harlow, KaLynn and Renwick, Allison and Shuping, Sydney and Sommer, Jeff and Knauer, Mark and Nestor, Casey}, year={2020}, month={Nov}, pages={212–212} }
 @article{merkley_shuping_nestor_2020, title={Neuronal networks that regulate gonadotropin-releasing hormone/luteinizing hormone secretion during undernutrition: evidence from sheep}, volume={3}, DOI={10.1016/j.domaniend.2020.106469}, journal={Domestic Animal Endocrinology}, publisher={Elsevier BV}, author={Merkley, C.M. and Shuping, S.L. and Nestor, C.C}, year={2020}, month={Oct}, pages={106469} }
 @article{estradiol protects proopiomelanocortin neurons against insulin resistance._2018, DOI={10.1210/en.2017-00793}, journal={Endocrinology}, year={2018}, month={Feb} }
 @article{nestor_bedenbaugh_hileman_coolen_lehman_goodman_2018, title={Regulation of GnRH pulsatility in ewes}, volume={156}, DOI={10.1530/REP-18-0127}, number={3}, journal={REPRODUCTION}, author={Nestor, Casey and Bedenbaugh, Michelle N. and Hileman, Stanley M. and Coolen, Lique M. and Lehman, Michael N. and Goodman, Robert L.}, year={2018}, pages={R83–99} }
 @article{padilla_qiu_nestor_zhang_smith_whiddon_rønnekleiv_kelly_palmiter_2017, title={AgRP to Kiss1 neuron signaling links nutritional state and fertility}, volume={114}, ISSN={0027-8424 1091-6490}, url={http://dx.doi.org/10.1073/pnas.1621065114}, DOI={10.1073/pnas.1621065114}, number={9}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Padilla, Stephanie L. and Qiu, Jian and Nestor, Casey C and Zhang, Chunguang and Smith, Arik W. and Whiddon, Benjamin B. and Rønnekleiv, Oline K. and Kelly, Martin J. and Palmiter, Richard D.}, year={2017}, month={Feb}, pages={2413–2418} }
 @article{agouti-related peptide neural circuits mediate adaptive behaviors in the starved state._2016, DOI={10.1038/nn.4274}, journal={Nature neuroscience}, year={2016}, month={Mar} }
 @article{qiu_nestor_zhang_padilla_palmiter_kelly_rønnekleiv_2016, title={High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons}, volume={5}, ISSN={2050-084X}, url={http://dx.doi.org/10.7554/eLife.16246}, DOI={10.7554/eLife.16246}, abstractNote={Kisspeptin (Kiss1) and neurokinin B (NKB) neurocircuits are essential for pubertal development and fertility. Kisspeptin neurons in the hypothalamic arcuate nucleus (Kiss1ARH) co-express Kiss1, NKB, dynorphin and glutamate and are postulated to provide an episodic, excitatory drive to gonadotropin-releasing hormone 1 (GnRH) neurons, the synaptic mechanisms of which are unknown. We characterized the cellular basis for synchronized Kiss1ARH neuronal activity using optogenetics, whole-cell electrophysiology, molecular pharmacology and single cell RT-PCR in mice. High-frequency photostimulation of Kiss1ARH neurons evoked local release of excitatory (NKB) and inhibitory (dynorphin) neuropeptides, which were found to synchronize the Kiss1ARH neuronal firing. The light-evoked synchronous activity caused robust excitation of GnRH neurons by a synaptic mechanism that also involved glutamatergic input to preoptic Kiss1 neurons from Kiss1ARH neurons. We propose that Kiss1ARH neurons play a dual role of driving episodic secretion of GnRH through the differential release of peptide and amino acid neurotransmitters to coordinate reproductive function.}, journal={eLife}, publisher={eLife Sciences Publications, Ltd}, author={Qiu, Jian and Nestor, Casey C and Zhang, Chunguang and Padilla, Stephanie L and Palmiter, Richard D and Kelly, Martin J and Rønnekleiv, Oline K}, year={2016}, month={Aug} }
 @article{nestor_qiu_padilla_zhang_bosch_fan_palmiter_rønnekleiv_kelly_aicher_2016, title={Optogenetic Stimulation of Arcuate Nucleus Kiss1 Neurons Reveals a Steroid-Dependent Glutamatergic Input to POMC and AgRP Neurons in Male Mice}, volume={30}, DOI={10.1210/me.2016-1026}, number={6}, journal={Molecular Endocrinology}, author={Nestor, CC and Qiu, J and Padilla, SL and Zhang, C and Bosch, MA and Fan, W and Palmiter, RD and Rønnekleiv, OK and Kelly, MJ and Aicher, SA}, year={2016}, pages={630–644} }
 @article{nestor_kelly_rønnekleiv_2014, title={Cross-talk between reproduction and energy homeostasis: central impact of estrogens, leptin and kisspeptin signaling}, volume={17}, ISSN={1868-1891 1868-1883}, url={http://dx.doi.org/10.1515/hmbci-2013-0050}, DOI={10.1515/hmbci-2013-0050}, abstractNote={Abstract}, number={3}, journal={Hormone Molecular Biology and Clinical Investigation}, publisher={Walter de Gruyter GmbH}, author={Nestor, Casey C. and Kelly, Martin J. and Rønnekleiv, Oline K.}, year={2014}, month={Jan} }
 @article{qiu_zhang_borgquist_nestor_smith_bosch_ku_wagner_rønnekleiv_kelly_2014, title={Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels}, volume={19}, ISSN={1550-4131}, url={http://dx.doi.org/10.1016/j.cmet.2014.03.004}, DOI={10.1016/j.cmet.2014.03.004}, number={4}, journal={Cell Metabolism}, publisher={Elsevier BV}, author={Qiu, Jian and Zhang, Chunguang and Borgquist, Amanda and Nestor, Casey C and Smith, Arik W. and Bosch, Martha A. and Ku, Stephen and Wagner, Edward J. and Rønnekleiv, Oline K. and Kelly, Martin J.}, year={2014}, month={Apr}, pages={682–693} }
 @article{porter_hileman_hardy_nestor_lehman_goodman_2014, title={Neurokinin-3 Receptor Activation in the Retrochiasmatic Area is Essential for the Full Pre-Ovulatory Luteinising Hormone Surge in Ewes}, volume={26}, ISSN={0953-8194}, url={http://dx.doi.org/10.1111/jne.12180}, DOI={10.1111/jne.12180}, number={11}, journal={Journal of Neuroendocrinology}, publisher={Wiley}, author={Porter, K. L. and Hileman, S. M. and Hardy, S. L. and Nestor, C. C and Lehman, M. N. and Goodman, R. L.}, year={2014}, month={Oct}, pages={776–784} }
 @article{rønnekleiv_fang_zhang_nestor_mao_kelly_2014, title={Research Resource: Gene Profiling of G Protein–Coupled Receptors in the Arcuate Nucleus of the Female}, volume={28}, ISSN={0888-8809 1944-9917}, url={http://dx.doi.org/10.1210/me.2014-1103}, DOI={10.1210/me.2014-1103}, number={8}, journal={Molecular Endocrinology}, publisher={The Endocrine Society}, author={Rønnekleiv, Oline K. and Fang, Yuan and Zhang, Chunguang and Nestor, Casey C. and Mao, Peizhong and Kelly, Martin J.}, year={2014}, month={Aug}, pages={1362–1380} }
 @article{nestor_coolen_nesselrod_valent_connors_hileman_cheng_lehman_goodman_2013, title={Evidence that Orphanin FQ Mediates Progesterone Negative Feedback in the Ewe}, volume={154}, ISSN={0013-7227 1945-7170}, url={http://dx.doi.org/10.1210/en.2013-1274}, DOI={10.1210/en.2013-1274}, number={11}, journal={Endocrinology}, publisher={The Endocrine Society}, author={Nestor, Casey C and Coolen, Lique M. and Nesselrod, Gail L. and Valent, Miro and Connors, John M. and Hileman, Stanley M. and Cheng, Guanliang and Lehman, Michael N. and Goodman, Robert L.}, year={2013}, month={Nov}, pages={4249–4258} }
 @article{goodman_hileman_nestor_porter_connors_hardy_millar_cernea_coolen_lehman_et al._2013, title={Kisspeptin, Neurokinin B, and Dynorphin Act in the Arcuate Nucleus to Control Activity of the GnRH Pulse Generator in Ewes}, volume={154}, ISSN={0013-7227 1945-7170}, url={http://dx.doi.org/10.1210/en.2013-1331}, DOI={10.1210/en.2013-1331}, number={11}, journal={Endocrinology}, publisher={The Endocrine Society}, author={Goodman, Robert L. and Hileman, Stanley M. and Nestor, Casey C and Porter, Katrina L. and Connors, John M. and Hardy, Steve L. and Millar, Robert P. and Cernea, Maria and Coolen, Lique M. and Lehman, Michael N. and et al.}, year={2013}, month={Nov}, pages={4259–4269} }
 @article{goodman_maltby_millar_hileman_nestor_whited_tseng_coolen_lehman_2012, title={Evidence That Dopamine Acts via Kisspeptin to Hold GnRH Pulse Frequency in Check in Anestrous Ewes}, volume={153}, ISSN={0013-7227 1945-7170}, url={http://dx.doi.org/10.1210/en.2012-1611}, DOI={10.1210/en.2012-1611}, number={12}, journal={Endocrinology}, publisher={The Endocrine Society}, author={Goodman, Robert L. and Maltby, Matthew J. and Millar, Robert P. and Hileman, Stanley M. and Nestor, Casey C and Whited, Brant and Tseng, Ashlie S. and Coolen, Lique M. and Lehman, Michael N.}, year={2012}, month={Dec}, pages={5918–5927} }
 @article{nestor_briscoe_davis_valent_goodman_hileman_2012, title={Evidence of a Role for Kisspeptin and Neurokinin B in Puberty of Female Sheep}, volume={153}, ISSN={0013-7227 1945-7170}, url={http://dx.doi.org/10.1210/en.2011-2009}, DOI={10.1210/en.2011-2009}, number={6}, journal={Endocrinology}, publisher={The Endocrine Society}, author={Nestor, Casey C and Briscoe, Amanda M.S. and Davis, Shay M. and Valent, Miro and Goodman, Robert L. and Hileman, Stanley M.}, year={2012}, month={Jun}, pages={2756–2765} }
 @article{goodman_holaskova_nestor_connors_billings_valent_lehman_hileman_2011, title={Evidence that the Arcuate Nucleus Is an Important Site of Progesterone Negative Feedback in the Ewe}, volume={152}, ISSN={0013-7227 1945-7170}, url={http://dx.doi.org/10.1210/en.2011-0195}, DOI={10.1210/en.2011-0195}, number={9}, journal={Endocrinology}, publisher={The Endocrine Society}, author={Goodman, Robert L. and Holaskova, Ida and Nestor, Casey C. and Connors, John M. and Billings, Heather J. and Valent, Miro and Lehman, Michael N. and Hileman, Stanley M.}, year={2011}, month={Sep}, pages={3451–3460} }
 @article{lin_huang_zhang_hollander_frisbee_martin_nestor_goodman_yu_2010, title={Inactivation of L-type calcium channel modulated by HCN2 channel}, volume={298}, ISSN={0363-6143 1522-1563}, url={http://dx.doi.org/10.1152/ajpcell.00355.2009}, DOI={10.1152/ajpcell.00355.2009}, abstractNote={ Ca<jats:sup>2+}, number={5}, journal={American Journal of Physiology-Cell Physiology}, publisher={American Physiological Society}, author={Lin, Yen-Chang and Huang, Jianying and Zhang, Qi and Hollander, John M. and Frisbee, Jefferson C. and Martin, Karen H. and Nestor, Casey and Goodman, Robert and Yu, Han-Gang}, year={2010}, month={May}, pages={C1029–C1037} }
 @article{billings_connors_altman_hileman_holaskova_lehman_mcmanus_nestor_jacobs_goodman_et al._2010, title={Neurokinin B Acts via the Neurokinin-3 Receptor in the Retrochiasmatic Area to Stimulate Luteinizing Hormone Secretion in Sheep}, volume={151}, ISSN={0013-7227 1945-7170}, url={http://dx.doi.org/10.1210/en.2010-0174}, DOI={10.1210/en.2010-0174}, number={8}, journal={Endocrinology}, publisher={The Endocrine Society}, author={Billings, Heather J. and Connors, John M. and Altman, Stephanie N. and Hileman, Stanley M. and Holaskova, Ida and Lehman, Michael N. and McManus, Christina J. and Nestor, Casey C and Jacobs, Britni H. and Goodman, Robert L. and et al.}, year={2010}, month={Aug}, pages={3836–3846} }
 @article{bogusz_hardy_lehman_connors_hileman_sliwowska_billings_mcmanus_valent_singh_et al._2008, title={Evidence that γ-Aminobutyric Acid Is Part of the Neural Circuit Mediating Estradiol Negative Feedback in Anestrous Ewes}, volume={149}, ISSN={0013-7227 1945-7170}, url={http://dx.doi.org/10.1210/en.2007-1362}, DOI={10.1210/en.2007-1362}, number={6}, journal={Endocrinology}, publisher={The Endocrine Society}, author={Bogusz, Adrienne L. and Hardy, Steven L. and Lehman, Michael N. and Connors, John M. and Hileman, Stanley M. and Sliwowska, Joanna H. and Billings, Heather J. and McManus, Christina J. and Valent, Miroslav and Singh, Sushma R. and et al.}, year={2008}, month={Jun}, pages={2762–2772} }