Works (124)

Updated: January 10th, 2024 05:01

2023 journal article

A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results from the CANN randomized, controlled parallel-design study

AMERICAN JOURNAL OF CLINICAL NUTRITION, 118(2), 369–381.

By: D. Vauzour*, A. Scholey*, D. White*, N. Cohen*, A. Cassidy*, R. Gillings*, M. Irvine*, C. Kay n ...

co-author countries: Australia 🇦🇺 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: omega-3; polyphenols; flavonoids; mild cognitive impairment; subjective cognitive impairment; aging; cognition
Sources: Web Of Science, ORCID
Added: September 5, 2023

2023 journal article

Almond intake alters the acute plasma dihydroxy-octadecenoic acid (DiHOME) response to eccentric exercise

FRONTIERS IN NUTRITION, 9.

By: D. Nieman*, A. Omar*, C. Kay n, D. Kasote n, C. Sakaguchi*, A. Lkhagva*, M. Weldemariam*, Q. Zhang*

co-author countries: United States of America 🇺🇸
author keywords: almonds; exercise; oxylipins; inflammation; cytokines; metabolites; (poly)phenols
Sources: Web Of Science, ORCID
Added: February 13, 2023

2023 journal article

Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health

Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro & beta;-Cell Functions Critical for Metabolic Health. METABOLITES, 13(7).

By: E. Krueger*, L. Griffin n, J. Beales*, T. Lloyd*, N. Brown*, W. Elison*, C. Kay n, A. Neilson n, J. Tessem*

co-author countries: United States of America 🇺🇸
author keywords: gut microbiome; phytochemicals; flavanol metabolites; glucose sensitivity; responder analysis; personalized nutrition
Sources: Web Of Science, ORCID
Added: August 14, 2023

2023 journal article

Performance of Urinary Phenyl-γ-Valerolactones as Biomarkers of Dietary Flavan-3-ol Exposure

JOURNAL OF NUTRITION, 153(8), 2193–2204.

By: B. Parmenter*, S. Shinde*, K. Croft*, K. Murray*, C. Bondonno*, A. Genoni*, C. Christophersen*, K. Bindon ...

co-author countries: Australia 🇦🇺 Denmark 🇩🇰 Italy 🇮🇹 United States of America 🇺🇸
author keywords: flavonoids; flavan-3-ols; phenyl-gamma-valerolactones; biomarkers; cocoa; apple; black tea; green tea
Sources: Web Of Science, ORCID
Added: January 8, 2024

2022 journal article

A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthy subjects

REDOX BIOLOGY, 51.

By: E. Cremonini*, E. Daveri*, D. Iglesias*, J. Kang*, Z. Wang*, R. Gray*, A. Mastaloudis*, C. Kay n ...

co-author countries: Argentina 🇦🇷 United States of America 🇺🇸
author keywords: Flavonoids; Obesity; Inflammation; Endotoxemia; Oxidative stress; Antioxidants
MeSH headings : Anthocyanins / pharmacology; Anthocyanins / therapeutic use; Blood Glucose / metabolism; Cross-Over Studies; Diet, High-Fat / adverse effects; Endotoxemia / metabolism; Healthy Volunteers; Humans; Insulin; Leukocytes, Mononuclear / metabolism
Sources: Web Of Science, ORCID
Added: June 20, 2022

2022 journal article

Blueberry anthocyanin intake attenuates the postprandial cardiometabolic effect of an energy-dense food challenge: Results from a double blind, randomized controlled trial in metabolic syndrome participants

CLINICAL NUTRITION, 41(1), 165–176.

By: P. Curtis*, L. Berends*, V. Velpen*, A. Jennings, L. Haag*, P. Chandra n, C. Kay n, E. Rimm*, A. Cassidy

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Metabolic syndrome; Postprandial assessment; Energy-dense meal challenge; Blueberry anthocyanins; Flavonoids; Cardiovascular disease risk
MeSH headings : Aged; Anthocyanins / administration & dosage; Anthocyanins / blood; Anthocyanins / urine; Blood Glucose / metabolism; Blood Pressure / drug effects; Blueberry Plants; Diet, Carbohydrate Loading / adverse effects; Diet, High-Fat / adverse effects; Double-Blind Method; Endothelium, Vascular / drug effects; Energy Intake / drug effects; Female; Humans; Insulin / blood; Lipoproteins / blood; Male; Meals / drug effects; Metabolic Syndrome / metabolism; Middle Aged; Postprandial Period / drug effects; Pulse Wave Analysis; Vascular Stiffness / drug effects
Sources: ORCID, Web Of Science
Added: November 27, 2021

2022 article

Boosting the Bioaccessibility of Dietary Bioactives by Delivery as Protein-Polyphenol Aggregate Particles

Lila, M. A., Hoskin, R. T., Grace, M. H., Xiong, J., Strauch, R., Ferruzzi, M., … Kay, C. (2022, April 8). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, Vol. 4.

By: M. Lila n, R. Hoskin n, M. Grace n, J. Xiong n, R. Strauch n, M. Ferruzzi*, M. Iorizzo n, C. Kay n

co-author countries: United States of America 🇺🇸
author keywords: bioavailability; digestion; absorption; circulation; uptake; matrix
MeSH headings : Humans; Polyphenols / analysis; Fruit / chemistry; Protein Aggregates; Dietary Proteins; Biological Availability; Food Ingredients
Sources: Web Of Science, ORCID
Added: April 14, 2022

2022 article

Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study

Racine, K. C., Iglesias-Carres, L., Herring, J. A., Ferruzzi, M. G., Kay, C. D., Tessem, J. S., & Neilson, A. P. (2022, January 31). (Vol. 1). Vol. 1.

By: K. Racine, L. Iglesias-Carres, J. Herring, M. Ferruzzi, C. Kay*, J. Tessem, A. Neilson

Source: ORCID
Added: February 2, 2022

2022 journal article

Cocoa extract exerts sex-specific anti-diabetic effects in an aggressive type-2 diabetes model: A pilot study

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 626, 205–210.

By: K. Racine*, L. Iglesias-Carres, J. Herring, M. Ferruzzi*, C. Kay*, J. Tessem, A. Neilson*

author keywords: BTBR; Ob/ob; Type-2 diabetes; Flavanol; Insulin; Beta cell
MeSH headings : Animals; Cacao; Diabetes Mellitus, Type 2 / drug therapy; Female; Humans; Hyperglycemia; Hyperinsulinism; Male; Mice; Obesity; Pilot Projects; Plant Extracts / pharmacology; Plant Extracts / therapeutic use
Sources: Web Of Science, ORCID
Added: October 17, 2022

2022 journal article

Effect of Wild Blueberry Metabolites on Biomarkers of Gastrointestinal and Immune Health In Vitro

Immuno, 2(2), 293–306.

By: T. Rathinasabapathy n, J. Lomax n, K. Srikanth*, D. Esposito n, C. Kay n & S. Komarnytsky n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: March 30, 2022

2022 article

Exploring the Contribution of (Poly)phenols to the Dietary Exposome Using High Resolution Mass Spectrometry Untargeted Metabolomics

Li, Y.-Y., Rushing, B., Schroder, M., Sumner, S., & Kay, C. D. (2022, February 25). MOLECULAR NUTRITION & FOOD RESEARCH, Vol. 2.

By: Y. Li*, B. Rushing*, M. Schroder*, S. Sumner* & C. Kay n

co-author countries: United States of America 🇺🇸
author keywords: dietary exposome; dietary exposome library (DEL); metabolites; polyphenols; untargeted metabolomics
MeSH headings : Humans; Chromatography, Liquid; Phenols; Tandem Mass Spectrometry / methods; Phenol; Exposome; Metabolomics / methods; Phytochemicals
Sources: ORCID, Web Of Science
Added: February 26, 2022

2022 journal article

Foaming and sensory characteristics of protein-polyphenol particles in a food matrix

Food Hydrocolloids.

By: J. Diaz n, E. Foegeding n, L. Stapleton*, C. Kay n, M. Iorizzo n, M. Ferruzzi n, M. Lila n

co-author countries: United States of America 🇺🇸
author keywords: Particles; Polyphenols; Proteins; Foaming; Sensory; Structure
Source: ORCID
Added: August 26, 2021

2022 journal article

Microbial Metabolites of Flavanols in Urine are Associated with Enhanced Anti-Proliferative Activity in Bladder Cancer Cells In Vitro

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 74(1), 194–210.

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Chromatography, Liquid; Gastrointestinal Microbiome; Polyphenols / analysis; Rats; Tandem Mass Spectrometry; Urinary Bladder Neoplasms / drug therapy
Sources: Web Of Science, ORCID
Added: February 10, 2021

2022 journal article

Spray-dried and freeze-dried protein-spinach particles; effect of drying technique and protein type on the bioaccessibility of carotenoids, chlorophylls, and phenolics

FOOD CHEMISTRY, 388.

By: M. Grace n, R. Hoskin n, M. Hayes n, M. Iorizzo n, C. Kay n, M. Ferruzzi n, M. Lila n

co-author countries: United States of America 🇺🇸
author keywords: Spinach phytochemicals; Whey protein; Soy protein; Drying; In vitro digestion; Dried ingredients
MeSH headings : Carotenoids / metabolism; Chlorophyll / metabolism; Digestion; Excipients / metabolism; Flavonoids / metabolism; Freeze Drying; Phenols / metabolism; Spinacia oleracea / metabolism
Sources: Web Of Science, ORCID
Added: June 13, 2022

2022 review

The berry health tool chest - an evidence map and interactive resource

[Review of ]. NUTRITION REVIEWS, 80(1), 68–77.

By: K. Kay n, R. Strauch n, C. Granillo n, M. Bame n, J. Xiong n, A. Mast n, B. Burton-Freeman*, C. Kay n, M. Lila n

co-author countries: United States of America 🇺🇸
author keywords: berry; clinical trial design; dietary intervention; evidence mapping; health criteria
MeSH headings : Eating; Fruit; Humans
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder

SCIENTIFIC REPORTS, 11(1).

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Disease Models, Animal; Female; Fetal Alcohol Spectrum Disorders / blood; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / microbiology; Gastrointestinal Microbiome; Male; Mice; Mothers; Pregnancy
Sources: ORCID, Web Of Science
Added: February 10, 2021

2021 article

Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyper-Glycemia Model: A Pilot Study

Racine, K. C., Iglesias-Carres, L., Herring, J. A., Ferruzzi, M. G., Kay, C. D., Tessem, J. S., & Neilson, A. P. (2021, December 7). (Vol. 12). Vol. 12.

By: K. Racine, L. Iglesias-Carres, J. Herring, M. Ferruzzi, C. Kay*, J. Tessem, A. Neilson

Source: ORCID
Added: December 10, 2021

2021 journal article

High-density linkage map construction and identification of loci regulating fruit quality traits in blueberry

HORTICULTURE RESEARCH, 8(1).

By: M. Mengist n, H. Bostan n, E. Young n, K. Kay*, N. Gillitt*, J. Ballington n, C. Kay n, M. Ferruzzi n ...

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 1, 2021

2021 article

Influence of simulated food and oral processing on carotenoid and chlorophyll in vitro bioaccessibility among six spinach genotypes

Hayes, M., Corbin, S., Nunn, C., Pottorff, M., Kay, C. D., Lila, M. A., … Ferruzzi, M. G. (2021, May 14). FOOD & FUNCTION, Vol. 5.

By: M. Hayes n, S. Corbin*, C. Nunn*, M. Pottorff*, C. Kay n, M. Lila n, M. Iorrizo n, M. Ferruzzi n

co-author countries: Belgium 🇧🇪 United States of America 🇺🇸
MeSH headings : Biological Availability; Carotenoids / chemistry; Carotenoids / metabolism; Carotenoids / pharmacokinetics; Chlorophyll / chemistry; Chlorophyll / metabolism; Chlorophyll / pharmacokinetics; Digestion; Genotype; Models, Biological; Spinacia oleracea / chemistry; Spinacia oleracea / genetics
Sources: ORCID, Web Of Science
Added: June 22, 2021

2021 journal article

Strawberry Consumption, Cardiometabolic Risk Factors, and Vascular Function: A Randomized Controlled Trial in Adults with Moderate Hypercholesterolemia

JOURNAL OF NUTRITION, 151(6), 1517–1526.

co-author countries: United States of America 🇺🇸
author keywords: strawberry; hypercholesterolemia; cardiovascular risk factors; flow-mediated dilation; (poly)phenolic metabolites
MeSH headings : Adult; Blood Pressure; Cardiometabolic Risk Factors; Cardiovascular Diseases / prevention & control; Cholesterol, LDL; Cross-Over Studies; Dietary Supplements; Female; Fragaria; Fruit; Humans; Hypercholesterolemia; Male; Middle Aged; Powders
Sources: Web Of Science, ORCID
Added: August 2, 2021

2020 journal article

Blueberry and/or Banana Consumption Mitigate Arachidonic, Cytochrome P450 Oxylipin Generation During Recovery From 75-Km Cycling: A Randomized Trial

FRONTIERS IN NUTRITION, 7.

By: D. Nieman*, N. Gillitt*, G. Chen*, Q. Zhang*, W. Sha*, C. Kay n, P. Chandra n, K. Kay*, M. Lila n

co-author countries: United States of America 🇺🇸
author keywords: exercise; lipid mediators; carbohydrate; polyphenols; metabolites; inflammation; fatty acids
Sources: Web Of Science, ORCID
Added: September 21, 2020

2020 journal article

Development of a genetic framework to improve the efficiency of bioactive delivery from blueberry

SCIENTIFIC REPORTS, 10(1).

By: M. Mengist n, H. Burtch n, H. Debelo n, M. Pottorff n, H. Bostan n, C. Nunn n, S. Corbin n, C. Kay n ...

co-author countries: United States of America 🇺🇸
MeSH headings : Blueberry Plants / genetics; Blueberry Plants / metabolism; Digestion; Flavonoids / metabolism; Genotype; Hydroxybenzoates / metabolism; In Vitro Techniques
Sources: Web Of Science, ORCID
Added: November 16, 2020

2020 journal article

In Vitro Bioaccessibility of Carotenoids and Chlorophylls in a Diverse Collection of Spinach Accessions and Commercial Cultivars

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 68(11), 3495–3505.

By: M. Hayes n, M. Pottorff n, C. Kay n, A. Van Deynze*, J. Osorio-Marin*, M. Lila n, M. Iorrizo n, M. Ferruzzi n

co-author countries: United States of America 🇺🇸
author keywords: spinach; carotenoids; lutein; beta-carotene; chlorophyll; genotypes; bioaccessibility; in vitro digestion
MeSH headings : Carotenoids; Chlorophyll; Chlorophyll A; Spinacia oleracea / genetics; beta Carotene
Sources: Web Of Science, ORCID
Added: May 8, 2020

2020 journal article

Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites

AMERICAN JOURNAL OF CLINICAL NUTRITION, 112(4), 1051–1068.

co-author countries: Australia 🇦🇺 Canada 🇨🇦 Germany 🇩🇪 Spain 🇪🇸 France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Italy 🇮🇹 United States of America 🇺🇸
author keywords: dietary (poly)phenols; microbial catabolites; phase II metabolites; nomenclature; food/diet metabolome
MeSH headings : Diet; Humans; Isomerism; Polyphenols / administration & dosage; Polyphenols / metabolism; Terminology as Topic
Sources: Web Of Science, ORCID
Added: November 16, 2020

2020 article

Supplemental treatment options for diabetes: how flavanol metabolites improve beta-cell function

Lloyd, T., Griffin, L., Krueger, E., Beales, J., Barlow, A., Sheets, J., … Tessem, J. (2020, April). FASEB JOURNAL, Vol. 34.

By: T. Lloyd*, L. Griffin n, E. Krueger*, J. Beales*, A. Barlow*, J. Sheets*, I. Ekpo*, M. Ross* ...

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: October 12, 2020

2020 review

Terms and nomenclature used for plant-derived components in nutrition and related research: efforts toward harmonization

[Review of ]. NUTRITION REVIEWS, 78(6), 451–458.

By: J. Frank*, N. Fukagawa*, A. Bilia*, E. Johnson*, O. Kwon*, V. Prakash*, T. Miyazawa*, M. Clifford* ...

co-author countries: Australia 🇦🇺 Germany 🇩🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 India 🇮🇳 Italy 🇮🇹 Japan 🇯🇵 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: bioactive; carotenoid; flavonoid; nomenclature; nutraceutical; phytochemical; phytonutrient; polyphenol
MeSH headings : Biomedical Research; Humans; Nutritional Sciences; Phytochemicals; Plant Preparations; Terminology as Topic
Sources: Web Of Science, ORCID
Added: June 29, 2020

2019 journal article

Adaptation of an in Vitro Digestion Model for High Throughput Phenolic Bioaccessibility Phenotyping Within Cultivated (highbush) Blueberry Varieties (P06-004-19)

Current Developments in Nutrition, 3(Supplement 1).

By: H. Burtch n, M. Ferruzzi n, C. Kay n, M. Lila n, M. Iorrizo n & M. Mengist n

co-author countries: United States of America 🇺🇸
Sources: NC State University Libraries, ORCID
Added: November 6, 2020

2019 journal article

Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome—results from a 6-month, double-blind, randomized controlled trial

The American Journal of Clinical Nutrition, 109(6), 1535–1545.

By: P. Curtis*, V. van der Velpen*, L. Berends*, A. Jennings*, M. Feelisch*, A. Umpleby*, M. Evans*, B. Fernandez* ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: metabolic syndrome; blueberry anthocyanins; flavonoids; cardiovascular disease risk; anthocyanin-derived phenolic acid metabolites
MeSH headings : Aged; Apolipoproteins / blood; Biomarkers / blood; Blood Pressure; Blueberry Plants / metabolism; Cholesterol, HDL / blood; Cholesterol, LDL / blood; Double-Blind Method; Female; Fruit / metabolism; Heart / physiopathology; Humans; Insulin Resistance; Male; Metabolic Syndrome / blood; Metabolic Syndrome / diet therapy; Metabolic Syndrome / physiopathology; Middle Aged; Prospective Studies; Pulse Wave Analysis
Sources: Crossref, ORCID
Added: December 5, 2019

2019 journal article

Contribution of Berry Polyphenols to the Human Metabolome

Molecules.

By: P. Chandra n, A. Rathore n, K. Kay*, J. Everhart n, P. Curtis*, B. Burton-Freeman*, A. Cassidy*, C. Kay n

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: mass spectrometry; metabolome; metabolomics; microbiome; (poly)phenol
MeSH headings : Anthocyanins / chemistry; Anthocyanins / pharmacokinetics; Blueberry Plants / chemistry; Fragaria / chemistry; Fruit / chemistry; Humans; Metabolome; Polyphenols / chemistry; Polyphenols / pharmacokinetics
Source: ORCID
Added: November 25, 2019

2019 journal article

Diversity in the Bioaccessibility of Carotenoid and Chlorophyll Compounds in 69 Spinach Genotypes (P06-007-19)

Current Developments in Nutrition, 3(Supplement 1).

By: M. Hayes n, M. Pottorff n, C. Kay n, A. Van Deynze*, J. Osorio-Marin*, M. Lila n, M. Iorrizo n, M. Ferruzzi n

co-author countries: United States of America 🇺🇸
Sources: NC State University Libraries, ORCID
Added: November 6, 2020

2019 journal article

Managing Risks Associated with Establishing the Metabolome of Dietary Phytochemicals (P06-010-19)

Current Developments in Nutrition, 3(Supplement 1).

By: C. Kay n, J. Everhart n & A. Rathore n

co-author countries: United States of America 🇺🇸
Sources: NC State University Libraries, ORCID
Added: November 6, 2020

2018 journal article

Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells

Molecules, 23(4), 898.

By: E. Warner*, I. Rodriguez-Ramiro*, M. O’Connell* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: anthocyanin; smooth muscle cells; metabolism; antioxidant; atherosclerosis
MeSH headings : Animals; Anthocyanins / chemistry; Anthocyanins / pharmacology; Aorta; Cell Proliferation / drug effects; Cells, Cultured; Gene Expression Regulation / drug effects; Heme Oxygenase (Decyclizing) / metabolism; Molecular Structure; Muscle, Smooth, Vascular / cytology; Muscle, Smooth, Vascular / drug effects; Muscle, Smooth, Vascular / metabolism; Phenols / chemistry; Phenols / pharmacology; Rats; Rats, Sprague-Dawley
Sources: Crossref, ORCID
Added: December 5, 2019

2018 journal article

Effect of adding milk to black tea on vascular function in healthy men and women: a randomised controlled crossover trial

Food & Function, 9(12), 6307–6314.

By: A. Ahmad*, L. Rich*, H. Koch*, K. Croft*, M. Ferruzzi n, C. Kay n, J. Hodgson*, N. Ward*

co-author countries: Australia 🇦🇺 United States of America 🇺🇸
MeSH headings : Adult; Animals; Blood Pressure; Brachial Artery / physiology; Camellia sinensis / chemistry; Camellia sinensis / metabolism; Cross-Over Studies; Female; Heart Rate; Humans; Male; Milk / metabolism; Tea / metabolism; Vasodilation; Young Adult
Sources: Crossref, ORCID
Added: December 8, 2019

2018 article

Increased Plasma Levels of Gut-Derived Phenolics Linked to Walking and Running Following 2-Weeks Flavonoid Supplementation

Nieman, D. C., Kay, C. D., Rathore, A. S., Grace, M. H., Strauch, R. C., Stephan, E. H., … Lila, M. A. (2018, October 15). (Vol. 10). Vol. 10.

By: D. Nieman, C. Kay*, A. Rathore, M. Grace, R. Strauch, E. Stephan, C. Sakaguchi, M. Lila*

Source: ORCID
Added: November 13, 2019

2018 journal article

Increased Plasma Levels of Gut-Derived Phenolics Linked to Walking and Running Following Two Weeks of Flavonoid Supplementation

Nutrients, 10(11).

By: D. Nieman*, C. Kay n, A. Rathore n, M. Grace n, R. Strauch n, E. Stephan*, C. Sakaguchi*, M. Lila n

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸

Contributors: D. Nieman*, C. Kay n, A. Rathore n, M. Grace n, R. Strauch n, E. Stephan*, C. Sakaguchi*, M. Lila n

author keywords: exercise; polyphenol; metabolite; hippurate; intestinal tract; colon
Source: ORCID
Added: November 12, 2019

2018 journal article

The Bioavailability, Transport, and Bioactivity of Dietary Flavonoids: A Review from a Historical Perspective

Comprehensive Reviews in Food Science and Food Safety, 17(5), 1054–1112.

By: G. Williamson*, C. Kay n & A. Crozier*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: bioactivity; bioavailability; dietary flavonoids; metabolism; transport
Sources: Crossref, ORCID
Added: December 5, 2019

2017 article

Anthocyanins and Flavanones Are More Bioavailable than Previously Perceived: A Review of Recent Evidence

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 8, Vol. 8, pp. 155–180.

co-author countries: Spain 🇪🇸 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: anthocyanins; flavanones; bioavailability; bioactivity
MeSH headings : Anthocyanins / pharmacokinetics; Anthocyanins / urine; Biological Availability; Colon / metabolism; Colon / microbiology; Diet; Flavanones / pharmacokinetics; Flavanones / urine; Fruit / metabolism; Gastrointestinal Microbiome; Humans; Kidney / metabolism; Phenols / pharmacokinetics; Vegetables / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Influence of Ingesting a Flavonoid-Rich Supplement On the Human Metabolome and Concentration of Urine Phenolics

The FASEB Journal, 31(Supplement 1), 972.26.

By: D. Nieman*, S. Ramamoorthy*, C. Kay n, C. Goodman*, C. Capps*, Z. Shue*, N. Heyl*, M. Grace n, M. Lila n

co-author countries: United States of America 🇺🇸
Sources: NC State University Libraries, ORCID
Added: November 6, 2020

2017 journal article

Influence of Ingesting a Flavonoid-Rich Supplement on the Metabolome and Concentration of Urine Phenolics in Overweight/Obese Women

JOURNAL OF PROTEOME RESEARCH, 16(8), 2924–2935.

By: D. Nieman*, S. Ramamoorthy*, C. Kay n, C. Goodman*, C. Capps*, Z. Shue*, N. Heyl*, M. Grace n, M. Lila n

co-author countries: United States of America 🇺🇸

Contributors: D. Nieman*, S. Ramamoorthy*, C. Kay n, C. Goodman*, C. Capps*, Z. Shue*, N. Heyl*, M. Grace n, M. Lila n

author keywords: dietary supplement; metabolomics; polyphenol; obesity
MeSH headings : Adolescent; Adult; Aged; Dietary Supplements; Female; Flavonoids / administration & dosage; Flavonoids / pharmacology; Humans; Intestinal Mucosa / metabolism; Metabolome / drug effects; Metabolomics / methods; Middle Aged; Obesity / metabolism; Obesity / urine; Overweight / metabolism; Overweight / urine; Phenols / urine; Young Adult
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells

Molecular Nutrition & Food Research, 61(9).

By: E. Warner*, M. Smith*, Q. Zhang*, K. Raheem*, D. O'Hagan*, M. O'Connell*, C. Kay n

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Anthocyanins / metabolism; Anthocyanins / pharmacology; Biomarkers; Cells, Cultured; Endothelial Cells / drug effects; Glucosides / pharmacology; Humans; Interleukin-6 / analysis; Interleukin-6 / antagonists & inhibitors; Interleukin-6 / genetics; Transcription Factor RelA / metabolism; Tumor Necrosis Factor-alpha / pharmacology; Vascular Cell Adhesion Molecule-1 / analysis; Vascular Cell Adhesion Molecule-1 / antagonists & inhibitors; Vascular Cell Adhesion Molecule-1 / genetics
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Acute benefits of the microbial-derived isoflavone metabolite equol on arterial stiffness in men prospectively recruited according to equol producer phenotype: a double-blind randomized controlled trial, 2

The American Journal of Clinical Nutrition, 103(3), 694–702.

Colin Kay

Source: ORCID
Added: November 13, 2019

2016 journal article

Common Phenolic Metabolites of Flavonoids, but Not Their Unmetabolized Precursors, Reduce the Secretion of Vascular Cellular Adhesion Molecules by Human Endothelial Cells--3

The Journal of Nutrition, 146(3), 465–473.

Colin Kay

Source: ORCID
Added: November 13, 2019

2016 conference paper

Elucidating metabolic signatures of phytochemical consumption

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 252.

By: C. Kay

Event: AMER CHEMICAL SOC 1155 16TH ST, NW, WASHINGTON, DC 20036 USA

Source: ORCID
Added: November 13, 2019

2015 journal article

Anthocyanins and their physiologically relevant metabolites alter the expression of IL-6 and VCAM-1 in CD40L and oxidized LDL challenged vascular endothelial cells

Molecular Nutrition & Food Research, 59(6), 1095–1106.

By: H. Amin*, C. Czank*, S. Raheem*, Q. Zhang*, N. Botting*, A. Cassidy*, C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: Adhesion molecule; Cytokine; Cyanidin-3-glucoside; Inflammation; Metabolites
MeSH headings : Anthocyanins / pharmacology; CD40 Ligand / metabolism; Coumaric Acids / metabolism; Endothelial Cells / cytology; Endothelial Cells / drug effects; Endothelial Cells / metabolism; Gene Expression; Glucosides / pharmacology; Glucuronides / metabolism; Human Umbilical Vein Endothelial Cells; Humans; Hydroxybenzoates / metabolism; Interleukin-6 / genetics; Interleukin-6 / metabolism; Lipoproteins, LDL / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Vascular Cell Adhesion Molecule-1 / genetics; Vascular Cell Adhesion Molecule-1 / metabolism
Source: Crossref
Added: February 9, 2020

2015 journal article

Anthocyanins and their physiologically relevant metabolites alter the expression of IL-6 and VCAM-1 in CD40L and oxidized LDL challenged vascular endothelial cells

Molecular Nutrition & Food Research, 59(6), 1095–1106.

Colin Kay

Source: ORCID
Added: November 13, 2019

2015 journal article

Flavonoid metabolites reduce tumor necrosis factor-α secretion to a greater extent than their precursor compounds in human THP-1 monocytes

Molecular Nutrition & Food Research, 59(6), 1143–1154.

By: J. di Gesso*, J. Kerr*, Q. Zhang*, S. Raheem*, S. Yalamanchili*, D. O'Hagan*, C. Kay*, M. O'Connell*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: Cytokine; Inflammation; Metabolism; Phase 2 conjugates; Polyphenol
MeSH headings : Cell Line; Cell Survival / drug effects; Flavonoids / chemistry; Flavonoids / pharmacology; Humans; Hydroxybenzoates / pharmacology; Interleukin-10 / metabolism; Interleukin-1beta / metabolism; Lipopolysaccharides / adverse effects; Monocytes / drug effects; NF-kappa B / genetics; NF-kappa B / metabolism; Parabens / pharmacology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Tumor Necrosis Factor-alpha / metabolism
Sources: Crossref, ORCID
Added: January 5, 2020

2015 journal article

Orange juice--derived flavanone and phenolic metabolites do not acutely affect cardiovascular risk biomarkers: a randomized, placebo-controlled, crossover trial in men at moderate risk of cardiovascular disease--

The American Journal of Clinical Nutrition, 101(5), 931–938.

Colin Kay

Source: ORCID
Added: November 13, 2019

2015 journal article

Phenolic Metabolites of Anthocyanins Modulate Mechanisms of Endothelial Function

Journal of Agricultural and Food Chemistry, 63(9), 2423–2431.

By: M. Edwards*, C. Czank*, G. Woodward*, A. Cassidy* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: endothelium; eNOS; cyanidin; HUVEC; NADPH-oxidase
MeSH headings : Anthocyanins / metabolism; Cell Line; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Nitric Oxide / metabolism; Nitric Oxide Synthase Type III / metabolism; Phenols / metabolism; Superoxides / metabolism
Sources: Crossref, ORCID
Added: November 13, 2019

2015 journal article

Rethinking paradigms for studying mechanisms of action of plant bioactives

Nutrition Bulletin, 40(4), 335–339.

By: C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: anti-inflammatory; bioactivity flavonoid; metabolism; microflora; vascular
Sources: Crossref, ORCID
Added: January 5, 2020

2015 conference paper

Sulfurophane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo

International Journal of Experimental Pathology, 96(2), A24.

By: R. Davidson, O. Jupp, R. de Ferrars, C. Kay, K. Culley, R. Norton, C. Driscoll, T. Vincent, S. Donell, Y. Bao

Event: Joint meeting of British Societies for Matrix Biology and Developmental Biology at University of East Anglia (Norwich) on September 1-3, 2014

Source: NC State University Libraries
Added: March 12, 2021

2015 journal article

The bioactivity of flavonoids is likely the result of cumulative low exposure to a variety of structurally similar phenolic metabolites

The FASEB Journal, 29(Supplement 1), 118.4.

By: C. Kay*, J. de Gesso*, E. Warner*, H. Amin*, R. de Ferrars*, M. Edwards*, Q. Zang*, D. O'Hagan*, M. O'Connell*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: NC State University Libraries, ORCID
Added: November 6, 2020

2014 journal article

A moderate-fat diet containing pistachios improves emerging markers of cardiometabolic syndrome in healthy adults with elevated LDL levels

British Journal of Nutrition, 112(5), 744–752.

By: S. Holligan*, S. West*, S. Gebauer*, C. Kay* & P. Kris-Etherton*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Pistachios; Small and dense LDL; HDL subclasses; Insulin resistance; Cardiometabolic disease; C-reactive protein; Plant sterols
MeSH headings : Anticholesteremic Agents / administration & dosage; Biomarkers / blood; C-Reactive Protein / analysis; Cardiovascular Diseases / blood; Cardiovascular Diseases / prevention & control; Cholesterol / blood; Cross-Over Studies; Dietary Fats / administration & dosage; Female; Humans; Insulin Resistance; Lipoproteins / blood; Lipoproteins, LDL / blood; Male; Metabolic Syndrome / blood; Metabolic Syndrome / prevention & control; Middle Aged; Nuts / chemistry; Phytosterols / administration & dosage; Phytotherapy; Pistacia; Sitosterols / blood; Triglycerides / blood
Sources: Crossref, ORCID
Added: November 13, 2019

2014 journal article

Methods for Isolating, Identifying, and Quantifying Anthocyanin Metabolites in Clinical Samples

Analytical Chemistry, 86(20), 10052–10058.

By: R. de Ferrars, C. Czank*, S. Saha*, P. Needs*, Q. Zhang*, K. Raheem*, N. Botting*, P. Kroon*, C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
MeSH headings : Anthocyanins / analysis; Chromatography, High Pressure Liquid; Tandem Mass Spectrometry
Sources: Crossref, ORCID
Added: November 13, 2019

2014 journal article

Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo

Osteoarthritis and Cartilage, 22, S322–S323.

By: R. Davidson*, O. Jupp*, R. de Ferrars*, C. Kay*, K. Culley*, R. Norton*, C. Driscoll*, T. Vincent* ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: January 5, 2020

2014 journal article

The pharmacokinetics of anthocyanins and their metabolites in humans

British Journal of Pharmacology, 171(13), 3268–3282.

By: R. De Ferrars, C. Czank, Q. Zhang, N. Botting, P. Kroon, A. Cassidy, C. Kay

Source: ORCID
Added: November 13, 2019

2013 article

A moderate-fat diet with pistachios lowers small-dense LDL and improves markers of insulin sensitivity in subjects with moderately-elevated cholesterol Levels

Federation of American Societies for Experimental Biology.

By: S. Holligan, S. West, S. Gebauer, C. Kay & P. Kris-Etherton

Source: ORCID
Added: November 13, 2019

2013 journal article

Absorption, distribution, metabolism and elimination of a stable isotope-labelled anthocyanin in humans

FASEB Journal, 27(Supplement 1), 125.6.

By: C. Kay, N. Botting, A. Cassidy, C. Czank, R. de Ferrars, P. Kroon, D. Morrison, T. Preston, Q. Zang

Event: Experimental Biology 2013 Meeting

Source: NC State University Libraries
Added: March 9, 2021

2013 journal article

Encyclopedia of Human Nutrition: Phytochemicals: Classification and Occurrence

By: C. Kay & A. Cassidy

Source: ORCID
Added: November 13, 2019

2013 journal article

Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study--

The American of Clinical Nutrition, 97(5), 995–1003.

Colin Kay

Source: ORCID
Added: November 13, 2019

2013 journal article

Metabolism of dietary flavonoids alters their effect on tumor necrosis factor-α

Cytokine, 63(3), 259.

By: J. di Gesso*, J. Kerr*, S. Yalamanchili*, A. Cassidy*, N. Botting*, D. O’Hagan*, Q. Zhang*, S. Raheen*, C. Kay*, M. O’Connell*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧

Event: SI: 2013 ICS at San Francisco, CA on September 29 - October 3, 2013

Sources: Crossref, ORCID, Web Of Science
Added: November 6, 2020

2013 journal article

Phenolic metabolites of anthocyanins following a dietary intervention study in post-menopausal women

Molecular Nutrition & Food Research, 58(3), 490–502.

By: R. de Ferrars, A. Cassidy*, P. Curtis* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: Anthocyanins; Elderberries; Glucuronide; Phenolic acids; Sulfate
MeSH headings : Anthocyanins / blood; Anthocyanins / metabolism; Anthocyanins / pharmacology; Anthocyanins / urine; Dietary Supplements; Female; Humans; Middle Aged; Phenols / blood; Phenols / metabolism; Phenols / urine; Plant Extracts / analysis; Plant Extracts / chemistry; Postmenopause; Sambucus / chemistry
Sources: Crossref, ORCID
Added: January 5, 2020

2013 chapter

Potential Health Benefits of Blackcurrants

In Bioactives in Fruit (pp. 215–250).

By: R. Miller*, S. Putnam*, M. Edwards*, G. Woodward* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: January 5, 2020

2013 chapter

Potential Health Benefits of Blackcurrants

In M. Skinner & D. Hunter (Eds.), Bioactives in fruit: health benefits and functional foods (pp. 215–250).

By: R. Miller*, S. Putnam*, M. Edwards*, G. Woodward* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧

Ed(s): M. Skinner & D. Hunter

Sources: NC State University Libraries, ORCID
Added: March 19, 2021

2013 journal article

Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo

Arthritis & Rheumatism, 65(12), 3130–3140.

By: R. Davidson*, O. Jupp*, R. de Ferrars*, C. Kay*, K. Culley*, R. Norton*, C. Driscoll*, T. Vincent* ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
MeSH headings : Animals; Arthritis, Experimental / metabolism; Cartilage, Articular / drug effects; Cartilage, Articular / metabolism; Cattle; Chondrocytes / drug effects; Chondrocytes / metabolism; Humans; Isothiocyanates / pharmacology; Matrix Metalloproteinases / metabolism; Mice; NF-E2-Related Factor 2 / metabolism; NF-kappa B / metabolism; Osteoarthritis / metabolism; Signal Transduction / drug effects; Signal Transduction / physiology; Sulfoxides
Sources: Crossref, ORCID
Added: November 13, 2019

2013 journal article

Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo

Osteoarthritis and Cartilage, 21, S217–S218.

By: R. Davidson*, O. Jupp*, R. de Ferrars*, C. Kay*, K. Culley*, R. Norton*, C. Driscoll*, T. Vincent* ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Source: Crossref
Added: March 8, 2020

2013 journal article

The metabolic fate of anthocyanins in humans

FASEB Journal, 27(Supplement 1), 125.7.

By: R. de Ferrars, A. Cassidy*, P. Curtis*, K. Raheem*, Q. Zhang* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧

Event: Experimental Biology 2013 Meeting at Boston, MA

Sources: NC State University Libraries, ORCID
Added: March 19, 2021

2013 journal article

Vascular bioactivity of anthocyanin degradants: inhibition of endothelial superoxide production

Proceedings of the Nutrition Society, 72(OCE4).

By: M. Edwards*, C. Czank*, A. Cassidy* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: November 13, 2019

2012 journal article

Dietary Flavonoids and Risk of Stroke in Women

Stroke, 43(4), 946–951.

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: citrus fruits; flavanones; flavonoids; hemorrhagic; ischemic; polyphenols; stroke
MeSH headings : Adult; Brain Ischemia / epidemiology; Brain Ischemia / prevention & control; Citrus; Dietary Supplements; Female; Flavonoids / administration & dosage; Follow-Up Studies; Fruit; Humans; Incidence; Intracranial Hemorrhages / epidemiology; Intracranial Hemorrhages / prevention & control; Middle Aged; Retrospective Studies; Stroke / epidemiology; Stroke / prevention & control; Surveys and Questionnaires; United States; United States Department of Agriculture
Source: Crossref
Added: January 5, 2020

2012 journal article

Dietary flavonoids and risk of stroke in women

Stroke, STROKEAHA-111.

Colin Kay

Source: ORCID
Added: November 13, 2019

2012 journal article

Diets Containing Pistachios Reduce Systolic Blood Pressure and Peripheral Vascular Responses to Stress in Adults With Dyslipidemia

Hypertension, 60(1), 58–63.

By: S. West*, S. Gebauer*, C. Kay*, D. Bagshaw*, D. Savastano*, C. Diefenbach*, P. Kris-Etherton*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: diet; stress; blood pressure; endothelium; total peripheral resistance; nuts; pistachios
MeSH headings : Adult; Blood Pressure / physiology; Brachial Artery / diagnostic imaging; Brachial Artery / physiopathology; Cardiac Output / physiology; Cross-Over Studies; Diet, Fat-Restricted / methods; Dose-Response Relationship, Drug; Dyslipidemias / physiopathology; Fasting; Heart Rate / physiology; Humans; Outcome Assessment, Health Care; Pistacia; Stress, Physiological / physiology; Ultrasonography; Vascular Resistance / physiology
Sources: Crossref, ORCID
Added: November 13, 2019

2012 journal article

Effect of cyanidin-glucoside and its metabolites on inflammatory biomarkers of vascular function

Proceedings of the Nutrition Society, 71(OCE2).

By: H. Amin*, C. Czank*, A. Cassidy* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: November 13, 2019

2012 journal article

Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials--

The American Journal of Clinical Nutrition, 95(3), 740–751.

Colin Kay

Source: ORCID
Added: November 13, 2019

2012 journal article

Effects of pistachios and walnuts on hemodynamic reactivity to stress: Clinical trials in adults with dyslipidemia

Australasian Medical Journal (Online, 5(12), 676.

By: S. West, S. Gebauer, C. Kay, A. Skulas-Ray & P. Kris-Etherton

Source: NC State University Libraries
Added: November 6, 2020

2012 journal article

Flavonoid metabolism: the synthesis of phenolic glucuronides and sulfates as candidate metabolites for bioactivity studies of dietary flavonoids

Tetrahedron, 68(22), 4194–4201.

By: Q. Zhang*, K. Raheem*, N. Botting*, A. Slawin*, C. Kay* & D. O'Hagan*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: Flavanoids; Metabolites; Phenolic glucuronides; Phenolic sulfates; Synthesis
Sources: Crossref, ORCID
Added: January 5, 2020

2012 journal article

Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women--

The American Journal of Clinical Nutrition, 96(4), 781–788.

By: A. Jennings, A. Welch, S. Fairweather-Tait, C. Kay, A. Minihane, P. Chowienczyk, B. Jiang, M. Cecelja ...

Source: ORCID
Added: November 13, 2019

2012 journal article

Investigating the bioavailability of anthocyanin metabolites

Proceedings of the Nutrition Society, 71(OCE2).

By: R. de Ferrars*, A. Cassidy*, P. Curtis*, C. Czank*, Q. Zhang*, K. Kalowole*, N. Botting*, C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: November 13, 2019

2012 journal article

Relative impact of flavonoid composition, dose and structure on vascular function: A systematic review of randomised controlled trials of flavonoid-rich food products

Molecular Nutrition & Food Research, 56(11), 1605–1616.

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Blood pressure; Cardiovascular disease; Dose response; Flavonoids; Flow-mediated dilation
MeSH headings : Biomarkers / metabolism; Blood Pressure / drug effects; Cardiovascular Diseases / diet therapy; Cardiovascular Diseases / drug therapy; Cardiovascular Diseases / metabolism; Catechin / pharmacology; Dose-Response Relationship, Drug; Endothelium, Vascular / drug effects; Endothelium, Vascular / physiology; Flavonoids / chemistry; Flavonoids / pharmacology; Flavonoids / therapeutic use; Humans; Proanthocyanidins / pharmacology; Randomized Controlled Trials as Topic; Regression Analysis; Structure-Activity Relationship; United States
Source: Crossref
Added: March 8, 2020

2012 journal article

Relative impact of flavonoid composition, dose and structure on vascular function: a systematic review of randomised controlled trials of flavonoid-rich food products

Molecular Nutrition & Food Research, 56(11), 1605–1616.

Colin Kay

Source: ORCID
Added: November 13, 2019

2012 journal article

Synthesis of [6, 8, 10, 3’, 5’-C-13 (5)]-cyanidin-3-glucoside, for human in vivo metabolism studies

Journal of Labelled Compounds & Radiopharmaceuticals, 55(3), 131–132.

By: Q. Zhang, N. Botting & C. Kay

Source: NC State University Libraries
Added: November 6, 2020

2012 journal article

The impact of human metabolism on the bioactivity of anthocyanins

Proceedings of the Nutrition Society, 71(OCE2).

By: C. Czank*, R. De Ferrars*, H. Amin*, P. Kroon*, Q. Zhang*, K. Kalowole*, N. Botting*, A. Cassidy*, C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: November 13, 2019

2012 journal article

Vascular bioactivity of anthocyanins and phenolic acid degradants: modulation of superoxide and nitric oxide

Proceedings of the Nutrition Society, 71(OCE2).

By: M. Edwards*, C. Czank*, A. Cassidy* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: January 5, 2020

2011 journal article

A gram scale synthesis of a multi-13 C-labelled anthocyanin,[6, 8, 10, 3′, 5′-13 C 5] cyanidin-3-glucoside, for use in oral tracer studies in humans

Chemical Communications, 47(38), 10596–10598.

By: Q. Zhang, N. Botting & C. Kay

Source: ORCID
Added: November 13, 2019

2011 journal article

A gram scale synthesis of a multi-13C-labelled anthocyanin, [6,8,10,3′,5′-13C5]cyanidin-3-glucoside, for use in oral tracer studies in humans

Chemical Communications, 47(38), 10596.

By: Q. Zhang*, N. Botting* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
MeSH headings : Administration, Oral; Anthocyanins / chemical synthesis; Anthocyanins / chemistry; Anthocyanins / pharmacokinetics; Carbon Isotopes / chemistry; Glucosides / chemical synthesis; Glucosides / chemistry; Glucosides / pharmacokinetics; Humans; Isotope Labeling; Stereoisomerism
Sources: Crossref, ORCID
Added: March 8, 2020

2011 journal article

A potential mechanism of action of dietary anthocyanins: modulation of endothelial superoxide production by phenolic acid metabolites

Proceedings of the Nutrition Society, 70(OCE4).

By: G. Woodward*, A. Cassidy* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: January 5, 2020

2011 journal article

Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation

Molecular Nutrition & Food Research, 55(3), 378–386.

By: G. Woodward, P. Needs & C. Kay

Source: ORCID
Added: November 13, 2019

2011 journal article

Anthocyanins Remain Stable during Commercial Blackcurrant Juice Processing

Journal of Food Science, 76(6), S408–S414.

By: G. Woodward*, D. McCarthy*, D. Pham-Thanh* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: anthocyanin; flavonoids; food processing; juice
MeSH headings : Anthocyanins / analysis; Anthocyanins / chemistry; Antioxidants / chemistry; Beverages / analysis; Chromatography, High Pressure Liquid; Filtration; Food Additives / chemistry; Food Additives / metabolism; Food Handling; Fruit / chemistry; Gallic Acid / analysis; Hot Temperature; Hydrolysis; Hydroxybenzoates / analysis; Models, Chemical; Pasteurization; Pectins / analysis; Pectins / metabolism; Phenols / analysis; Polygalacturonase / metabolism; Ribes / chemistry; Sulfites / chemistry; United Kingdom
Sources: Crossref, ORCID
Added: January 5, 2020

2011 conference paper

Effects of pistachios on emerging CVD risk factors in moderately hypercholesterolemic individuals

The FASEB Journal, 25(S1), 971.21.

By: S. Holligan, S. Gebauer*, S. West*, C. Kay* & P. Kris-Etherton

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸

Event: Federation of American Societies for Experimental Biology 2011 Meeting at Washington, DC

Sources: NC State University Libraries, ORCID
Added: March 19, 2021

2011 journal article

Effects of sugar-sweetened and sugar-free cocoa on endothelial function in overweight adults

International Journal of Cardiology, 149(1), 83–88.

By: V. Njike*, Z. Faridi*, K. Shuval*, S. Dutta*, C. Kay*, S. West*, P. Kris-Etherton*, D. Katz*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Cocoa; Endothelial function; Cardiac risk
MeSH headings : Adult; Biomarkers / metabolism; Brachial Artery / drug effects; Brachial Artery / physiology; Cacao; Cardiovascular Diseases / diet therapy; Cardiovascular Diseases / epidemiology; Cardiovascular Diseases / prevention & control; Cholesterol / blood; Cross-Over Studies; Dietary Sucrose / administration & dosage; Endothelium, Vascular / drug effects; Endothelium, Vascular / physiology; Female; Humans; Male; Middle Aged; Overweight / diet therapy; Overweight / epidemiology; Placebos; Risk Factors; Vasodilation / drug effects; Vasodilation / physiology
Sources: Crossref, ORCID
Added: November 13, 2019

2011 chapter

Phytochemicals

In Nutrition and Metabolism (pp. 339–352).

By: A. Cassidy & C. Kay*

Sources: Crossref, ORCID
Added: January 5, 2020

2011 journal article

Reply to C Drossard et al

The American Journal of Clinical Nutrition, 93(4), 866–867.

By: A. Cassidy*, C. Kay* & E. Rimm*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: January 5, 2020

2010 journal article

Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation

Molecular Nutrition & Food Research, 55(3), 378–386.

By: G. Woodward*, P. Needs* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: Anthocyanins; Glucuronide; Metabolism; Phenolic acids
MeSH headings : Analysis of Variance; Anthocyanins / metabolism; Chromatography, High Pressure Liquid; Digestion; Glucosides / metabolism; Glucuronides / chemical synthesis; Glucuronides / metabolism; Humans; Hydroxybenzoates / chemical synthesis; Hydroxybenzoates / metabolism; Intestinal Mucosa / metabolism; Male; Microsomes, Liver / metabolism; Parabens / metabolism
Source: Crossref
Added: September 11, 2020

2010 journal article

Anthocyanins form potentially-bioactive phenolic degradation products under simulated physiological conditions

Proceedings of the Nutrition Society, 69(OCE1).

By: G. Woodward*, A. Cassidy*, P. Kroon* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: January 5, 2020

2010 journal article

CVD risk biomarkers and liver and kidney function are not modified following 12-week ingestion of an elderberry extract rich in anthocyanins

Proceedings of the Nutrition Society, 69(OCE1).

By: P. Curtis*, P. Kroon*, W. Hollands*, R. Walls*, C. Kay*, G. Jenkins*, A. Cassidy*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: January 5, 2020

2010 journal article

Habitual intake of flavonoid subclasses and incident hypertension in adults--

The American Journal of Clinical Nutrition, 93(2), 338–347.

Colin Kay

Source: ORCID
Added: November 13, 2019

2010 journal article

Pistachios increase serum antioxidants and lower serum oxidized-LDL in hypercholesterolemic adults

The Journal of Nutrition, 140(6), 1093–1098.

By: C. Kay, S. Gebauer, S. West & P. Kris-Etherton

Source: ORCID
Added: November 13, 2019

2010 journal article

The future of flavonoid research

British Journal of Nutrition, 104(S3), S91–S95.

By: C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: Flavonoid; Bioactivity; Bioavailability; Metabolism
MeSH headings : Biological Availability; Biomedical Research; Diet; Flavonoids / metabolism; Flavonoids / pharmacology; Phenols / metabolism; Phenols / pharmacology; Polyphenols
Sources: Crossref, ORCID
Added: November 13, 2019

2009 journal article

Acute Fish Oil and Soy Isoflavone Supplementation Increase Postprandial Serum (n-3) Polyunsaturated Fatty Acids and Isoflavones but Do Not Affect Triacylglycerols or Biomarkers of Oxidative Stress in Overweight and Obese Hypertriglyceridemic Men

The Journal of Nutrition, 139(6), 1128–1134.

By: H. Hanwell*, C. Kay*, J. Lampe*, B. Holub* & A. Duncan*

co-author countries: Canada 🇨🇦 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Biomarkers; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Fatty Acids, Omega-3 / blood; Fish Oils / administration & dosage; Fish Oils / pharmacology; Humans; Hypertriglyceridemia / blood; Isoflavones / blood; Isoflavones / pharmacology; Male; Middle Aged; Overweight / blood; Oxidative Stress / physiology; Postprandial Period; Soybeans; Triglycerides / blood
Sources: Crossref, ORCID
Added: January 5, 2020

2009 journal article

Anthocyanin Stability and Recovery: Implications for the Analysis of Clinical and Experimental Samples

Journal of Agricultural and Food Chemistry, 57(12), 5271–5278.

By: G. Woodward*, P. Kroon*, A. Cassidy* & C. Kay*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: Degradation; anthocyanin; phenolic acids; flavonoid; stability
MeSH headings : Anthocyanins / chemistry; Anthocyanins / metabolism; Humans; Models, Biological
Sources: Crossref, ORCID
Added: November 13, 2019

2009 journal article

Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks

The Journal of Nutrition, 139(12), 2266–2271.

Colin Kay

Source: ORCID
Added: November 13, 2019

2009 journal article

Soy protein isoflavones, serum lipids and markers of oxidation and inflammation

Journal of Nutrition, 139, 1–7.

By: C. Hanwell, C. Kay, B. Holub & A. Duncan

Source: NC State University Libraries
Added: March 26, 2021

2009 journal article

The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products

Molecular Nutrition & Food Research, 53(S1), S92–S101.

By: C. Kay*, P. Kroon* & A. Cassidy*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
author keywords: Anthocyanin; Degradation; Flavonoid; Metabolite; Phenolic
MeSH headings : Anthocyanins / administration & dosage; Anthocyanins / chemistry; Anthocyanins / metabolism; Biological Availability; Caco-2 Cells; Culture Media; Diet; Drug Stability; Glucosides / chemistry; Glucosides / metabolism; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics
Sources: Crossref, ORCID
Added: November 13, 2019

2008 journal article

Bioactivity, absorption, and metabolism of anthocyanins

Recent Advances in Polyphenol Research, 1, 228–262.

By: G. Mazza & C. Kay

Source: ORCID
Added: November 13, 2019

2008 journal article

Effects of pistachios on cardiovascular disease risk factors and potential mechanisms of action: a dose-response study--

The American Journal of Clinical Nutrition, 88(3), 651–659.

By: S. Gebauer, S. West, C. Kay, P. Alaupovic, D. Bagshaw & P. Kris-Etherton

Source: ORCID
Added: November 13, 2019

2008 journal article

The major intestinal metabolites of anthocyanins are unlikely to be conjugates of their parent compounds but metabolites of their degradation products

Proceedings of the Nutrition Society, 67(OCE8).

By: C. Kay*, P. Kroon* & A. Cassidy*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: January 5, 2020

2007 chapter

Clinical Nutrition Studies

In Handbook of Nutrition and Food, Second Edition (pp. 693–714).

By: T. Psota, S. West, P. Kris-Etherton, D. Maddox Bagshaw & C. Kay*

Sources: Crossref, ORCID
Added: November 13, 2019

2007 conference paper

Effect of acute fish oil and soy isoflavone supplementation on postprandial serum triglycerides and biomarkers of oxidative stress in overweight or obese, hypertriglyeridemic men

The FASEB Journal, 21(5), A370.

By: H. Courtney*, C. Kay*, J. Lampe*, B. Holub* & A. Duncan*

co-author countries: Canada 🇨🇦 United States of America 🇺🇸

Event: Federation of American Societies for Experimental Biology 2007

Sources: NC State University Libraries, ORCID
Added: March 26, 2021

2007 journal article

Pistachios Reduce Blood Pressure and Vascular Responses to Acute Stress in Healthy Adults

The FASEB Journal, 21(5).

By: S. West*, C. Kay*, S. Gebauer*, D. Savastano*, C. Diefenbach* & P. Kris‐Etherton

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 3, 2020

2007 chapter

Pistachios beneficially affect multiple lipid and apolipoprotein CVD risk factors

In The FASEB Journal (Vol. 21, p. A695).

By: S. Gebauer, C. Kay*, S. West*, P. Alaupovic*, T. Psota & P. Kris-Etherton

co-author countries: United States of America 🇺🇸

Event: Federation of American Societies for Experimental Biology Meeting

Sources: NC State University Libraries, ORCID
Added: March 26, 2021

2007 article

Pistachios reduce serum oxidized LDL and increase serum antioxidant levels

Federation of American Societies for Experimental Biology.

By: C. Kay, S. Gebauer, S. West & P. Kris-Etherton

Source: ORCID
Added: November 13, 2019

2006 journal article

Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans

Nutrition Research Reviews, 19(1), 137–146.

By: C. Kay*

co-author countries: United States of America 🇺🇸
author keywords: anthocyanins; flavonoids; pharmacokinetics; metabolites
Sources: Crossref, ORCID
Added: November 13, 2019

2006 journal article

Effects of antioxidant-rich foods on vascular reactivity: Review of the clinical evidence

Current Atherosclerosis Reports, 8(6), 510–522.

By: C. Kay*, P. Kris-Etherton & S. West*

co-author countries: United States of America 🇺🇸
MeSH headings : Antioxidants / pharmacology; Cardiovascular Diseases / diet therapy; Cardiovascular Diseases / physiopathology; Food, Fortified; Humans; Prognosis; Vascular Resistance / drug effects
Sources: Crossref, ORCID
Added: November 13, 2019

2006 conference paper

Inflammatory status modifies the actions of n3 fatty acids on vascular function

The FASEB Journal, 20(4), A10.

By: C. Kay*, P. Kris-Etherton*, B. Holub*, K. Hecker* & S. West*

co-author countries: Belgium 🇧🇪 Canada 🇨🇦 United States of America 🇺🇸

Event: Federation of American Societies for Experimental Biology Meeting

Sources: NC State University Libraries, ORCID
Added: March 26, 2021

2005 chapter

Anthocyanins and Cancer Prevention

In Nutrition and Cancer Prevention.

By: B. Holub & C. Kay*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: December 5, 2019

2005 journal article

Anthocyanins exist in the circulation primarily as metabolites in adult men

The Journal of Nutrition, 135(11), 2582–2588.

By: C. Kay, G. Mazza & B. Holub

Source: ORCID
Added: November 13, 2019

2004 thesis

Analysis of the bioactivity, metabolism, and pharmacokinetics of anthocyanins in humans

(Thesis). University of Guelph, Guelph, Ont.

By: C. Kay

Source: NC State University Libraries
Added: March 29, 2021

2004 journal article

Anthocyanin metabolites in human urine and serum

British Journal of Nutrition, 91(6), 933–942.

By: C. Kay*, G. Mazza*, B. Holub* & J. Wang*

co-author countries: Canada 🇨🇦
author keywords: flavonoids; cyanidin 3-glycosides; glucurottide; methylated anthocyanins
MeSH headings : Adult; Anthocyanins / blood; Anthocyanins / metabolism; Anthocyanins / urine; Blueberry Plants; Chromatography, High Pressure Liquid / methods; Fruit / metabolism; Gas Chromatography-Mass Spectrometry / methods; Glucosides / blood; Glucosides / metabolism; Glucosides / urine; Humans; Hydrolysis; Male; Mass Spectrometry / methods; Middle Aged; Plant Extracts / administration & dosage; Plant Extracts / metabolism
Sources: Crossref, Web Of Science, ORCID
Added: November 13, 2019

2004 journal article

Methods of analysis for anthocyanins in plants and biological fluids

Journal of AOAC International, 87(1), 129–145.

By: G. Mazza, J. Cacace & C. Kay

Source: ORCID
Added: November 13, 2019

2003 conference paper

Anthocyanins Absorption and Serum Antioxidant Status in Humans

The 12th World Food Congress.

By: G. Mazza, C. Kay & B. Holub

Source: NC State University Libraries
Added: March 29, 2021

2003 journal article

The postprandial effects of dietary antioxidants in humans

Current Atherosclerosis Reports, 5(6), 452.

By: C. Kay & B. Holub

Source: ORCID
Added: November 13, 2019

2002 journal article

Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects

Journal of Agricultural and Food Chemistry, 50(26), 7731–7737.

By: G. Mazza, C. Kay, T. Cottrell & B. Holub

Source: ORCID
Added: November 13, 2019

2002 thesis

Assessment of the in Vivo Antioxidant Potential of Wild Blueberries in Humans

(Thesis). University of Guelph, Guelph, Ont.

By: C. Kay

Source: NC State University Libraries
Added: March 29, 2021

2002 journal article

The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects

British Journal of Nutrition, 88(4), 389–397.

By: C. Kay & B. Holub

Source: ORCID
Added: November 13, 2019

2000 journal article

Activity and concentration of polyphenolic antioxidants in apple: Effect of cultivar, harvest year and storage condition.

Pakistan Journal of Biological Sciences, 11(12), 1056–1067.

By: M. Hajimahmoodi, M. Oveisi, N. Sadeghi, B. Jannat, M. Hadjibabaie, E. Farahani, M. Akrami, R. Namdar ...

Source: ORCID
Added: November 13, 2019

1991 report

Agroindustria rural en Venezuela

Quito, Ecuador: Instituto Latinoamericano de Fomento Agroindustrial.

By: A. Kesteren, E. Izquierdo, J. Serrano, A. Rodda, M. Lois, C. Revilla, E. Nolte, D. Padilla, J. Rocha, J. Restrepo

Source: NC State University Libraries
Added: March 29, 2021

Employment

Updated: February 20th, 2024 11:06

2022 - present

University of Arkansas for Medical Sciences Little Rock, US
Professor Pediatrics

Education

Updated: October 1st, 2018 11:55

1995 - present

University of Guelph Guelph, ON, CA
PhD Nutrition

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