Courtney Klotz

Works (5)

Updated: July 5th, 2023 15:35

2020 article

Deletion of S-Layer Associated Ig-Like Domain Protein Disrupts the Lactobacillus acidophilus Cell Surface

Klotz, C., Goh, Y. J., Sarah, O. F., Johnson, B., & Barrangou, R. (2020, March 17). Frontiers in Microbiology, Vol. 11.

By: C. Klotz n, Y. Goh n, O. Sarah n, B. Johnson n & R. Barrangou n 

author keywords: Lactobacillus; probiotic; S-layer; cell surface; S-layer associated protein; Ig-like domain
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Gut microbiota and health
TL;DR: Identification of similar proteins in alternative bacterial species may help pinpoint next-generation host-adapted probiotic candidates. (via Semantic Scholar)
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15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020

2019 article

CRISPR Cinema: Scenes from the Cutting Edge

Klotz, C. (2019, April 1). The CRISPR Journal.

By: C. Klotz n

MeSH headings : CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Genetic Engineering / ethics; Humans; Motion Pictures
topics (OpenAlex): CRISPR and Genetic Engineering; Innovation and Socioeconomic Development
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Source: Web Of Science
Added: May 20, 2019

2018 article

Engineering Components of the Lactobacillus S-Layer for Biotherapeutic Applications

Klotz, C., & Barrangou, R. (2018, October 2). Frontiers in Microbiology, Vol. 9.

By: C. Klotz n & R. Barrangou n 

author keywords: Lactobacillus; probiotic; S-layer; biotherapeutic; mucosal vaccine; CRISPR
topics (OpenAlex): Probiotics and Fermented Foods; Transgenic Plants and Applications; Viral gastroenteritis research and epidemiology
TL;DR: The multi-faceted S-layer protein (Slp), and its use in both heterologous protein expression systems and mucosal vaccine delivery frameworks, is examined, through its diverse genetic components. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018

2017 journal article

Alterations to metabolically active bacteria in the mucosa of the small intestine predict anti-obesity and anti-diabetic activities of grape seed extract in mice

Food & Function, 8(10), 3510–3522.

By: L. Griffin *, K. Witrick *, C. Klotz*, M. Dorenkott*, K. Goodrich*, G. Fundaro*, R. McMillan *, M. Hulver *, M. Ponder *, A. Neilson* 

MeSH headings : Animals; Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Blood Glucose / metabolism; Diabetes Mellitus / drug therapy; Diabetes Mellitus / metabolism; Diabetes Mellitus / microbiology; Diet, High-Fat / adverse effects; Gastrointestinal Microbiome / drug effects; Grape Seed Extract / administration & dosage; Humans; Insulin / metabolism; Intestine, Small / metabolism; Intestine, Small / microbiology; Male; Mice; Mice, Inbred C57BL; Obesity / drug therapy; Obesity / metabolism; Obesity / microbiology; Vitis / chemistry
topics (OpenAlex): Gut microbiota and health; Diet and metabolism studies; Nutritional Studies and Diet
TL;DR: Grape seed extract can prevent early changes in glucose tolerance and alter small intestinal gut microbiota, prior to the onset of skeletal muscle metabolic derangements, when grape seed extract is consumed at a low dose in the context of a moderately high fat diet. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2017 article

Investigating the Effect of Growth Phase on the Surface-Layer Associated Proteome of Lactobacillus acidophilus Using Quantitative Proteomics

Klotz, C., O'Flaherty, S., Goh, Y. J., & Barrangou, R. (2017, November 7). Frontiers in Microbiology, Vol. 8.

By: C. Klotz n, S. O'Flaherty n, Y. Goh n & R. Barrangou n 

author keywords: Lactobacillus; probiotic; cell surface; S-layer; quantitative proteomics
topics (OpenAlex): Probiotics and Fermented Foods; Bacteriophages and microbial interactions; Genomics and Phylogenetic Studies; Advanced Proteomics Techniques and Applications; Glycosylation and Glycoproteins Research
TL;DR: This study establishes a framework for quantifying condition-dependent changes to cell surface proteins that can easily be applied to other S-layer forming bacteria. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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