David Huang

College of Sciences

Works (2)

Updated: July 8th, 2023 21:14

2022 journal article

Phylogeny-guided microbiome OTU-specific association test (POST)

MICROBIOME, 10(1).

By: C. Huang  n, B. Callahan n , M. Wu *, S. Holloway n, H. Brochu n , W. Lu n, X. Peng n , J. Tzeng n

author keywords: Association test; Phylogenetic tree; Kernel machine regression
MeSH headings : Computational Biology / methods; Computer Simulation; Female; Humans; Infant, Newborn; Microbiota / genetics; Phylogeny; Premature Birth
TL;DR: This work proposes a local collapsing test called phylogeny-guided microbiome OTU-specific association test (POST), and develops a user friendly R package POSTm, which can enhance the selection performance of associated microbiome features by improving the overall true-positive and false-positive detection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 20, 2022

2021 journal article

Development of targeted therapy of NRF2(high) esophageal squamous cell carcinoma

CELLULAR SIGNALLING, 86.

By: C. Paiboonrungruang*, E. Simpson*, Z. Xiong*, C. Huang  n, J. Li, Y. Li *, X. Chen *

author keywords: Esophageal squamous cell carcinoma; NRF2
MeSH headings : Animals; Cell Line, Tumor; Esophageal Neoplasms / drug therapy; Esophageal Neoplasms / pathology; Esophageal Squamous Cell Carcinoma / drug therapy; Esophageal Squamous Cell Carcinoma / pathology; Mice; NF-E2-Related Factor 2
TL;DR: This review focuses on three aspects, NRF2 inhibitors and their mechanisms of action, screening novel drug targets, and evaluation ofNRF2 activity in the esophagus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: September 20, 2021

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