Ca2+ signaling–mediated low-intensity pulsed ultrasound–induced proliferation and activation of motor neuron cells
Truong, T.-T., Chiu, W.-T., Lai, Y.-S., Huang, H., Jiang, X., & Huang, C.-C. (2022, March 29). Ultrasonics, Vol. 124.
author keywords: Low-intensity pulsed ultrasound; Motor neuron disease; NSC-34 cell line; Neurite outgrowth; Morphology; Ca (2+) signaling; Ca (2+) -dependent transcription factors
MeSH headings : Animals; Calcium Signaling; Cell Proliferation; Mice; Motor Neurons / physiology; NF-kappa B; Ultrasonic Waves
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Nerve injury and regeneration; Tendon Structure and Treatment
TL;DR:
It is suggested that the LIPUS-induced Ca2+ signaling and transcription factor activation facilitate the morphological maturation and proliferation of NSC-34 cells, presenting a promising noninvasive method to improve stimulation therapy for MNDs in the future.
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