@article{silva_laska_brown_sederoff_khodakovskaya_2011, title={Arabidopsis thaliana calcium-dependent lipid-binding protein (AtCLB): a novel repressor of abiotic stress response}, volume={62}, ISSN={["1460-2431"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-79957467259&partnerID=MN8TOARS}, DOI={10.1093/jxb/erq468}, abstractNote={Ca(2+) is an important second messenger in plant signal transduction pathways regulating stress-induced gene expression. Functional analysis of plant proteins containing Ca(2+)-binding domains (C2 domains) will help us understand the mechanisms behind the role of transcriptional regulators in the Ca(2+) signalling pathway and open new perspectives for crop genetic improvement. We identified a novel transcriptional regulator, a Ca(2+)-dependent lipid-binding protein (AtCLB) containing a C2 domain. AtCLB binds specifically to the promoter of the Arabidopsis thalianol synthase gene (AtTHAS1), whose expression is induced by gravity and light. Here we describe the role of the Atclb gene encoding the AtCLB protein. Expression of the Atclb gene was documented in all analysed tissues of Arabidopsis (leaf, root, stem, flower, and silique) by real-time PCR analysis. Immunofluorescence analysis revealed that AtCLB protein is localized in the nucleus of cells in Arabidopsis root tips. We demonstrated that the AtCLB protein was capable of binding to the membrane lipid ceramide. The role of the Atclb gene in negatively regulating responses to abiotic stress in Arabidopsis thaliana was identified. The loss of the Atclb gene function confers an enhanced drought and salt tolerance and a modified gravitropic response in T-DNA insertion knockout mutant lines. Expression of AtTHAS1 in Atclb knockout mutant lines was increased compared with wild type and a 35S-Atclb overexpression line suggesting AtCLB as a transcriptional repressor of AtTHAS1.}, number={8}, journal={JOURNAL OF EXPERIMENTAL BOTANY}, author={Silva, Kanishka and Laska, Bozena and Brown, Christopher and Sederoff, Heike Winter and Khodakovskaya, Mariya}, year={2011}, month={May}, pages={2679–2689} }
 @article{brown_rezvanian_zikry_krim_2009, title={Temperature dependence of asperity contact and contact resistance in gold RF MEMS switches}, volume={19}, number={2}, journal={Journal of Micromechanics and Microengineering}, author={Brown, C. and Rezvanian, O. and Zikry, M. A. and Krim, J.}, year={2009} }
 @article{brown_morris_kingon_krim_2008, title={Cryogenic Performance of RF MEMS Switch Contacts}, volume={17}, ISSN={["1941-0158"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-57449110516&partnerID=MN8TOARS}, DOI={10.1109/JMEMS.2008.2005328}, abstractNote={A series of experiments was performed to characterize RF microelectromechanical system switch performance under variable environmental conditions and cryogenic temperatures. Data were recorded in helium and nitrogen environments to lower stiction failure rates as well as to circumvent switch bouncing arising from low pressure at cryogenic temperatures. Contact resistance values were observed to be lower at cryogenic temperatures but still two orders of magnitude higher than the values predicted for the constriction resistance of gold asperity contacts, consistent with the presence of adsorbed films on the contacts. An asperity-heating model was applied, from which it was deduced that contact voltages can selectively disassociate adsorbed films from the contact surface while not softening the gold asperity contacts. The results are consistent with the reduced mobility of the adsorbed surface films at cryogenic temperatures.}, number={6}, journal={JOURNAL OF MICROELECTROMECHANICAL SYSTEMS}, author={Brown, Chris and Morris, Arthur S., III and Kingon, Angus I. and Krim, Jacqueline}, year={2008}, month={Dec}, pages={1460–1467} }
 @article{rezvanian_zikry_brown_krim_2007, title={Surface roughness, asperity contact and gold RFMEMS switch behavior}, volume={17}, ISSN={["1361-6439"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-34748865043&partnerID=MN8TOARS}, DOI={10.1088/0960-1317/17/10/012}, abstractNote={Modeling predictions and experimental measurements were obtained to characterize the electro-mechanical response of radio frequency (RF) microelectromechanical (MEM) switches due to variations in surface roughness and finite asperity deformations. Three-dimensional surface roughness profiles were generated, based on a Weierstrass–Mandelbrot fractal representation, to match the measured roughness characteristics of contact bumps of manufactured RF MEMS switches. Contact asperity deformations due to applied contact pressures were then obtained by a creep constitutive formulation. The contact pressure is derived from the interrelated effects of roughness characteristics, material hardening and softening, temperature increases due to Joule heating and contact forces. This modeling framework was used to understand how contact resistance evolves due to changes in the real contact area, the number of asperities in contact, and the temperature and resistivity profiles at the contact points. The numerical predictions were qualitatively consistent with the experimental measurements and observations of how contact resistance evolves as a function of deformation time history. This study provides a framework that is based on integrated modeling and experimental measurements, which can be used in the design of reliable RF MEMS devices with extended life cycles.}, number={10}, journal={JOURNAL OF MICROMECHANICS AND MICROENGINEERING}, author={Rezvanian, O. and Zikry, M. A. and Brown, C. and Krim, J.}, year={2007}, month={Oct}, pages={2006–2015} }