Works (1)
Updated: July 5th, 2023 15:34
2018 journal article
A Distalless-responsive enhancer of the Hox gene Sex combs reduced is required for segment- and sex-specific sensory organ development in Drosophila
PLOS GENETICS, 14(4).
MeSH headings : Animals; Animals, Genetically Modified; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Drosophila melanogaster / growth & development; Drosophila melanogaster / metabolism; Enhancer Elements, Genetic / genetics; Extremities / growth & development; Female; Gene Expression Regulation, Developmental; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Larva / genetics; Larva / growth & development; Larva / metabolism; Male; Mutation; Sense Organs / growth & development; Sense Organs / metabolism; Sex Factors; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
This work has identified two cis-regulatory elements that control spatially modulated Scr expression within T1 legs and shows that this enhancer functions to integrate Scr into the intrasegmental gene regulatory network, such that Scr serves as a link between leg patterning, sex determination, and sensory organ development.
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journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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