Works (37)

2022 journal article

Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal stem cells

GUT MICROBES, 14(1).

By: B. Sheahan, C. Theriot, J. Cortes & C. Dekaney

author keywords: Microbiota; intestinal stem cells; doxorubicin; antibiotics; antimicrobials; DNA damage; germ free; injury; small intestine
Source: Web Of Science
Added: January 18, 2022

2021 journal article

Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 12(1), 119–140.

By: B. Sheahan, A. Freeman n, T. Keeley*, L. Samuelson*, J. Roper*, S. Hasapis*, C. Lee*, C. Dekaney

author keywords: Gastrointestinal; irradiation; LGR5; DNA damage response
Source: Web Of Science
Added: August 16, 2021

2021 article

Hyperproliferation of the Intestinal Epithelium

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, Vol. 12, pp. 1145–1146.

By: C. Dekaney

Source: Web Of Science
Added: September 20, 2021

2021 journal article

Multiomic analysis defines the first microRNA atlas across all small intestinal epithelial lineages and reveals novel markers of almost all major cell types

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 321(6), G668–G681.

By: M. Shanahan*, M. Kanke*, O. Oyesola*, Y. Hung*, K. Koch-Laskowski*, A. Singh*, B. Peck*, M. Biraud ...

author keywords: intestinal epithelium; marker; microRNA; Paneth; tuft
Source: Web Of Science
Added: January 3, 2022

2021 review

Secretory Sorcery: Paneth Cell Control of Intestinal Repair and Homeostasis

[Review of ]. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 12(4), 1239–1250.

By: P. Cray, B. Sheahan & C. Dekaney

author keywords: Paneth cells; damage; intestine; ER stress; reversion
Source: Web Of Science
Added: November 8, 2021

2020 journal article

Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

SCIENTIFIC REPORTS, 10(1).

By: P. Cray, B. Sheahan, J. Cortes & C. Dekaney

Source: Web Of Science
Added: January 11, 2021

2020 journal article

Enteroendocrine Progenitor Cell-Enriched mir-7 Regulates Intestinal Epithelial Proliferation in an Xiap-Dependent Manner

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 9(3), 447–464.

By: A. Singh*, Y. Hung*, M. Shanahan*, M. Kanke*, A. Bonfini*, M. Dame*, M. Biraud, B. Peck* ...

author keywords: miR-7; Enteroendocrine Lineage; Small Intestine; Enteroid; Proliferation
Sources: Web Of Science, ORCID
Added: April 6, 2020

2019 journal article

Cellular Plasticity of Defa4(Cre)-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 7(3), 533–554.

By: J. Jones, C. Brindley*, N. Elder*, M. Myers*, M. Rajala*, C. Dekaney, E. McNamee*, M. Frey*, N. Shroyer*, P. Dempsey*

author keywords: Defensin; Paneth Cell; Intestinal Stem Cells; Regeneration; Enteroid; Notch; Chemotherapy
Source: Web Of Science
Added: May 6, 2019

2019 journal article

Mist1 Expression Is Required for Paneth Cell Maturation

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 8(4), 549–560.

By: C. Dekaney, S. King n, B. Sheahan & J. Cortes

author keywords: MIST1; Paneth Cells; Intermediate Cells
Source: Web Of Science
Added: December 16, 2019

2018 article

Decrypting the Crypt: Novel Monoclonal Antibodies to Identify Intestinal Stem Cell Populations

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, Vol. 6, pp. 121–122.

By: B. Sheahan & C. Dekaney

Source: Web Of Science
Added: August 6, 2018

2016 journal article

Intestinal bacteria are necessary for doxorubicin-induced intestinal damage but not for doxorubicin-induced apoptosis

Gut Microbes, 7(5), 414–423.

By: R. Rigby*, J. Carr*, K. Orgel*, S. King n, P. Lund* & C. Dekaney

author keywords: apoptosis; bacteria; damage; doxorubicin; germ free; intestine
Source: Crossref
Added: February 21, 2020

2015 journal article

1009 Depletion of Enteric Microbiota Protects from Chemotherapy-Induced Damage in the Murine Small Intestine

Gastroenterology, 148(4), S-1132.

By: J. Carr, S. King & C. Dekaney

Source: Crossref
Added: February 21, 2020

2015 journal article

798 Mist1 Is Necessary for Paneth Cell Maturation

Gastroenterology, 148(4), S-156-S-157.

By: S. King, J. Carr & C. Dekaney

Source: Crossref
Added: February 21, 2020

2015 journal article

Tissue underlying the intestinal epithelium elicits proliferation of intestinal stem cells following cytotoxic damage

Cell and Tissue Research, 361(2), 427–438.

By: K. Seiler*, E. Schenhals*, R. von Furstenberg*, B. Allena*, B. Smith*, D. Scaria*, M. Bresler*, C. Dekaney, S. Henning*

author keywords: Doxorubicin damage; Intestinal stem cells; Chordin-like 2; Subepithelial tissue; Amphiregulin; BMP antagonists
Source: Crossref
Added: July 20, 2019

2013 journal article

Mo1824 Jejunal and Ileal Epithelium Demonstrate Differing Damage Responses to Doxorubicin Treatment

Gastroenterology, 144(5), S-672.

By: K. Gewain, S. King & C. Dekaney

Source: Crossref
Added: March 13, 2020

2013 journal article

Paneth cells expand from newly created and preexisting cells during repair after doxorubicin-induced damage

American Journal of Physiology-Gastrointestinal and Liver Physiology, 305(2), G151–G162.

By: S. King*, J. Mohiuddin* & C. Dekaney

author keywords: Paneth cell; doxorubicin; intermediate cell
Source: Crossref
Added: July 20, 2019

2013 journal article

Small Intestinal Stem Cells

Current Opinion in Gastroenterology, 29, 140–145.

By: S. King & C. Dekaney

Source: NC State University Libraries
Added: September 8, 2019

2013 journal article

Tu2027 The Chemotherapeutic Agent Doxorubicin Induces Contrasting Microbial Responses in the Jejunum and Distal Ileum That May Contribute to Differential Injury Patterns

Gastroenterology, 144(5), S-907-S-908.

By: C. Packey, K. Gewain, R. Sartor & C. Dekaney

Source: Crossref
Added: March 13, 2020

2011 journal article

Characterization Of Intestinal Stem Cells During Development: The Role Of Lgr5

Journal of Surgical Research, 165(2), 339.

By: J. Dehmer, A. Garrison, K. Speck, C. Dekaney, S. Henning & M. Helmrath

Source: Crossref
Added: August 28, 2020

2011 journal article

Expansion of Intestinal Epithelial Stem Cells during Murine Development

PLoS ONE, 6(11), e27070.

By: J. Dehmer*, A. Garrison*, K. Speck*, C. Dekaney, L. Van Landeghem*, X. Sun*, S. Henning*, M. Helmrath*

Ed(s): M. Rota

Source: Crossref
Added: July 20, 2019

2010 journal article

750 Germ Free Mice Show Apoptosis but Dramatically Reduced Overt Mucosal Damage After Doxorubicin

Gastroenterology, 138(5), S-103.

By: R. Rigby, P. Lund & C. Dekaney

Source: Crossref
Added: August 28, 2020

2010 journal article

T1727 Paneth Cells Expand From a Pre-Existing Pool During Repair After Doxorubicin-Induced Damage

Gastroenterology, 138(5), S-566.

By: C. Dekaney

Source: Crossref
Added: February 12, 2021

2009 journal article

488 Regeneration of Intestinal Stem Cells Following Doxorubicin Treatment of Mice

Gastroenterology, 136(5), A-79.

By: C. Dekaney, A. Gulati, M. Helmrath & S. Henning

Source: Crossref
Added: August 28, 2020

2009 journal article

Early but not late administration of glucagon-like peptide-2 following ileo-cecal resection augments putative intestinal stem cell expansion

American Journal of Physiology-Gastrointestinal and Liver Physiology, 296(3), G643–G650.

By: A. Garrison*, C. Dekaney, D. von Allmen*, P. Lund*, S. Henning* & M. Helmrath*

author keywords: intestinal adaptation
Source: Crossref
Added: July 20, 2019

2009 journal article

Regeneration of intestinal stem/progenitor cells following doxorubicin treatment of mice

American Journal of Physiology-Gastrointestinal and Liver Physiology, 297(3), G461–G470.

By: C. Dekaney, A. Gulati, A. Garrison*, M. Helmrath* & S. Henning*

author keywords: crypt fission; apoptosis; Paneth cells; goblet cells; Lgr5
Source: Crossref
Added: July 20, 2019

2008 journal article

163. Timing of Glucagon-Like Peptide-2 (GLP-2) Required for Augmented Expansion of Intestinal Stem Cells Following Ileo-Cecal Resection (ICR) in Mice

Journal of Surgical Research, 144(2), 249–250.

By: A. Garrison*, C. Dekaney, D. von Allmen*, S. Henning* & M. Helmrath*

Source: Crossref
Added: August 28, 2020

2008 journal article

29. Bacterial Dependent up Regulation of Ileal Bile Acid Binding Protein and Bile Acid Transporters Is FXR-Mediated Following Ileo-Cecal Resection (ICR)

Journal of Surgical Research, 144(2), 188–189.

By: C. Dekaney, D. von Allmen*, A. Garrison*, R. Rigby*, P. Lund*, S. Henning*, M. Helmrath*

Source: Crossref
Added: August 28, 2020

2008 journal article

Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection

Surgery, 144(2), 174–181.

By: C. Dekaney, D. von Allmen*, A. Garrison*, R. Rigby*, P. Lund*, S. Henning*, M. Helmrath*

Source: Crossref
Added: July 20, 2019

2008 journal article

Developmental insight into intestinal adaptation: characterization of intestinal stem cell (ISC) expansion and glucagon-like peptide-2 (GLP-2) actions during murine intestinal development

Journal of the American College of Surgeons, 207(3), S55–S56.

By: A. Garrison*, C. Dekaney, D. von Allmen*, S. Henning* & M. Helmrath*

Source: Crossref
Added: January 21, 2021

2008 journal article

Regulation of ornithine aminotransferase gene expression and activity by all-transretinoic acid in Caco-2 intestinal epithelial cells

The Journal of Nutritional Biochemistry, 19(10), 674–681.

By: C. Dekaney, G. Wu, Y. Yin & L. Jaeger*

author keywords: retinoic acid; ornithine aminotransferase; polyamines; intestinal cells
Source: Crossref
Added: August 28, 2020

2008 journal article

T1818 Early Administration of Glucagon-Like Peptide-2 (GLP-2) Following Ileocecal Resection Augments Insulin-Like Growth Factor-I (IGF-I) Signaling During Intestinal Stem Cell Expansion

Gastroenterology, 134(4), A-569-A-570.

By: A. Garrison, C. Dekaney, D. von Allmen, P. Lund, S. Henning & M. Helmrath

Source: Crossref
Added: January 21, 2021

2007 journal article

Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice

American Journal of Physiology-Gastrointestinal and Liver Physiology, 293(5), G1013–G1022.

By: C. Dekaney, J. Fong*, R. Rigby*, P. Lund*, S. Henning* & M. Helmrath*

author keywords: intestinal stem cells; intestinal resection; crypt fission; label retention
Source: Crossref
Added: July 20, 2019

2007 journal article

Rapid expansion of intestinal secretory lineages following a massive small bowel resection in mice

American Journal of Physiology-Gastrointestinal and Liver Physiology, 292(1), G215–G222.

By: M. Helmrath*, J. Fong*, C. Dekaney & S. Henning*

author keywords: intestinal adaptation; intestinal failure; Paneth cells; goblet cells
Source: Crossref
Added: July 20, 2019

2006 journal article

Massive small bowel resection results in sustained increases in intestinal stem cell number

Journal of Surgical Research, 130(2), 253.

By: C. Dekaney, J. Fong, J. Rodriguez, S. Henning & M. Helmrath

Source: Crossref
Added: August 28, 2020

2006 journal article

Reply

Gastroenterology, 130(3), 1013–1014.

By: C. Dekaney, J. Rodriguez, M. Graul & S. Henning

Source: Crossref
Added: August 28, 2020

2005 journal article

Isolation and Characterization of a Putative Intestinal Stem Cell Fraction From Mouse Jejunum

Gastroenterology, 129(5), 1567–1580.

By: C. Dekaney, J. Rodriguez*, M. Graul* & S. Henning*

Source: Crossref
Added: July 20, 2019

2004 journal article

Early activation of Wnt β-catenin system following a massive small bowel resection in mice

Journal of Surgical Research, 121(2), 309–310.

By: M. Helmrath*, J. Fong*, C. Dekaney & H. Henning*

Source: Crossref
Added: August 28, 2020