Carla M. Haslauer

Works (5)

Updated: July 5th, 2023 15:53

2011 journal article

Collagen-PCL Sheath-Core Bicomponent Electrospun Scaffolds Increase Osteogenic Differentiation and Calcium Accretion of Human Adipose-Derived Stem Cells

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 22(13), 1695–1712.

By: C. Haslauer n, A. Moghe n, J. Osborne n, B. Gupta n & E. Loboa n

author keywords: Biomedical applications; tissue engineering; fibers; nanostructures; human adipose-derived stem cells; electrospinning
MeSH headings : Adipose Tissue / cytology; Adipose Tissue / metabolism; Bone and Bones; Calcium / metabolism; Cell Differentiation; Cell Proliferation; Collagen / chemistry; Humans; Microscopy, Electron, Scanning; Nanofibers / chemistry; Osteogenesis; Polyesters / chemistry; Polymers; Stem Cells / cytology; Stem Cells / metabolism; Tissue Engineering; Tissue Scaffolds
TL;DR: The sheath-core composite fibers significantly increased calcium accretion of hASCs, indicating that collagen–PCL sheath–core bicomponent structures have potential for bone tissue engineering applications using h ASCs. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2010 journal article

Fiber-reinforced scaffolds for tissue engineering and regenerative medicine: use of traditional textile substrates to nanofibrous arrays

JOURNAL OF MATERIALS CHEMISTRY, 20(40), 8776–8788.

By: S. McCullen*, C. Haslauer* & E. Loboa n

TL;DR: Fiber reinforcement continues to be an ideal strategy for tissue scaffolds that require mechanical reinforcement while providing high surface volume in a compliant form and next steps to expand this field are discussed. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2010 journal article

In Situ Monitoring of Adipogenesis with Human-Adipose-Derived Stem Cells Using Surface-Enhanced Raman Spectroscopy

APPLIED SPECTROSCOPY, 64(11), 1227–1233.

By: B. Moody n, C. Haslauer n, E. Kirk n, A. Kannan n, E. Loboa n & G. McCarty n 

author keywords: Raman spectroscopy; Adipogenesis; Stem cells; Surface-enhanced Raman spectroscopy; SERS
MeSH headings : Adipogenesis / physiology; Adipose Tissue / cytology; Adipose Tissue / metabolism; Adult; Cells, Cultured; Endocytosis; Female; Gold Colloid / chemistry; Gold Colloid / pharmacokinetics; Humans; Metal Nanoparticles / chemistry; Microscopy, Electron, Transmission; Spectrum Analysis, Raman / methods; Stem Cells / cytology; Stem Cells / metabolism
TL;DR: It is shown that intracellular SERS is able to detect the production of lipids as little as one day after the onset of adipogenesis and that a complex interplay between lipids, proteins, and chemical messengers can be observed shortly thereafter. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Musculoskeletal mechanobiology: Interpretation by external force and engineered substratum

JOURNAL OF BIOMECHANICS, 43(1), 119–127.

By: S. McCullen n, C. Haslauer n & E. Loboa n

author keywords: Mechanobiology; Musculoskeletal; External forces; Cell-substrate interactions
MeSH headings : Adenosine Triphosphate / metabolism; Animals; Biomechanical Phenomena; Cytoskeleton / physiology; Humans; Mechanotransduction, Cellular; Muscle, Skeletal / physiology; Nitric Oxide / metabolism; Stress, Mechanical; Tensile Strength
TL;DR: This review outlines many of the main mechanotransduction mechanisms known to date, and describes recent literature examining effects of both external forces and cell-substrate interactions on musculoskeletal cells. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 journal article

Cyclic tensile strain increases interactions between human epidermal keratinocytes and quantum dot nanoparticles

TOXICOLOGY IN VITRO, 22(2), 491–497.

By: J. Rouse n, C. Haslauer n, E. Loboa n & N. Monteiro-Riviere n 

Contributors: J. Rouse n, C. Haslauer n, E. Loboa n & N. Monteiro-Riviere n 

author keywords: quantum dot nanoparticles; keratinocytes; skin; tensile strain; cellular uptake
MeSH headings : Borates / toxicity; Cell Membrane Permeability / drug effects; Cell Survival / drug effects; Cells, Cultured; Cytokines / analysis; Cytokines / biosynthesis; Epidermal Cells; Epidermis / drug effects; Ethidium; Fluoresceins; Fluorescent Dyes; Humans; Keratinocytes / drug effects; Keratinocytes / physiology; Microscopy, Fluorescence; Pharmaceutical Vehicles / chemistry; Polyethylene Glycols / chemistry; Quantum Dots; Tensile Strength
TL;DR: Application of physiological load conditions can increase cell membrane permeability, thereby increasing the concentration of QD nanoparticles in cells, and addition of strain results in an increase in cytokine production and QD uptake, resulting in irritation and a negative impact on cell viability. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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