Chie Tamamoto-Mochizuki

Works (7)

Updated: April 5th, 2024 11:51

2023 article

Introduction to the ICADA 2023 canine atopic dermatitis pathogenesis review articles and updated definition

Eisenschenk, M. C., Hensel, P., Saridomichelakis, M. N., Tamamoto-Mochizuki, C., Pucheu-Haston, C. M., & Santoro, D. (2023, December 14). VETERINARY DERMATOLOGY.

By: M. Eisenschenk, P. Hensel, M. Saridomichelakis *, C. Tamamoto-Mochizuki n, C. Pucheu-Haston * & D. Santoro *

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Added: January 2, 2024

2023 article

Update on the role of cytokines and chemokines in canine atopic dermatitis

Tamamoto-Mochizuki, C., Santoro, D. N., Saridomikelakis, M., Eisenschenk, M. N. C., Hensel, P., Pucheu-Haston, C., & ICADA, I. C. A. D. A. (2023, July 23). VETERINARY DERMATOLOGY.

By: C. Tamamoto-Mochizuki n, D. Santoro *, M. Saridomikelakis*, M. Eisenschenk, P. Hensel, C. Pucheu-Haston *, I. Icada

author keywords: allergy; cytokines; dog; hypersensitivity; skin
TL;DR: Advances in technologies have allowed the simultaneous analysis of a broader range of cytokines and chemokines, which revealed an upregulation of a multipolar immunological axis in cAD. (via Semantic Scholar)
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Added: August 14, 2023

2023 article

Update on the role of genetic factors, environmental factors and allergens in canine atopic dermatitis

Hensel, P., Saridomichelakis, M., Eisenschenk, M., Tamamoto-Mochizuki, C., Pucheu-Haston, C., Santoro, D., & IDADA. (2023, October 15). VETERINARY DERMATOLOGY.

By: P. Hensel, M. Saridomichelakis *, M. Eisenschenk, C. Tamamoto-Mochizuki n, C. Pucheu-Haston *, D. Santoro *, Idada

author keywords: allergy; dog; house dust mites; hygiene hypothesis; major allergens
TL;DR: The current evidence on the role of genetic and environmental factors and allergic sensitisation in the pathogenesis of cAD since the last review by ICADA is summarized. (via Semantic Scholar)
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Added: November 13, 2023

2023 article

Update on the skin barrier, cutaneous microbiome and host defence peptides in canine atopic dermatitis

Santoro, D., Saridomichelakis, M., Eisenschenk, M., Tamamoto-Mochizuki, C., Hensel, P., & Pucheu-Haston, C. (2023, November 22). VETERINARY DERMATOLOGY.

By: D. Santoro *, M. Saridomichelakis *, M. Eisenschenk, C. Tamamoto-Mochizuki n, P. Hensel & C. Pucheu-Haston *

author keywords: ceramides; cutaneous dysbiosis; filaggrin; host defence peptides
TL;DR: The understanding of the cutaneous host-microbe interaction is still unclear, as is the role that cutaneous dysbiosis plays in the development and/or worsening of canine AD, and more studies are needed aiming to design new therapeutic approaches to restore the skin barrier. (via Semantic Scholar)
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Added: December 11, 2023

2021 review

IL-31 and IL-31 receptor expression in acute experimental canine atopic dermatitis skin lesions

[Review of ]. VETERINARY DERMATOLOGY, 32(6), 631-+.

By: C. Tamamoto-Mochizuki n & T. Olivry n 

MeSH headings : Animals; Dermatitis, Atopic / veterinary; Dog Diseases; Dogs; Interleukins; Keratinocytes; Skin
TL;DR: The early and transient production of IL-31 by Th cells supports the concept of usingIL-31 inhibiting strategies as a proactive therapy to prevent flares of AD skin lesions. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 19, 2021

2020 journal article

Efficacy study of a topical treatment with a plant extract with antibiofilm activities using an in vivo model of canine superficial pyoderma

VETERINARY DERMATOLOGY, 31(2), 86–89.

By: W. Baeumer, M. Jacobs  n & C. Tamamoto-Mochizuki n

MeSH headings : Administration, Topical; Animals; Anti-Bacterial Agents / administration & dosage; Biofilms / drug effects; Cross-Over Studies; Disease Models, Animal; Dog Diseases / drug therapy; Dogs; Female; Male; Microbial Sensitivity Tests; Plant Extracts / administration & dosage; Proof of Concept Study; Pyoderma / drug therapy; Pyoderma / veterinary; Skin / microbiology; Skin / pathology; Staphylococcus / drug effects
TL;DR: Topical application of W16P576 markedly reduced lesion development in this proof of principle study and clinical trials are warranted to estimate benefits for dogs with naturally occurring pyoderma under field conditions. (via Semantic Scholar)
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Added: December 2, 2019

2019 journal article

Proactive maintenance therapy of canine atopic dermatitis with the anti‐ IL ‐31 lokivetmab. Can a monoclonal antibody blocking a single cytokine prevent allergy flares?

Veterinary Dermatology, 30(2), 98–e26.

By: C. Tamamoto‐Mochizuki  n, J. Paps n & T. Olivry n 

Contributors: C. Tamamoto-Mochizuki n, J. Paps n & T. Olivry n 

TL;DR: Although lokivetmab seems more effective to prevent pruritus than skin lesions in dogs with experimental AD' it also can delay disease flares in some dogs with the spontaneous disease. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: April 2, 2019

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