@article{galiakhmetov_davern_esteves_awosanya_guthrie_proulx_nevzorov_2022, title={Aligned peptoid-based macrodiscs for structural studies of membrane proteins by oriented-sample NMR}, volume={121}, ISSN={["1542-0086"]}, DOI={10.1016/j.bpj.2022.07.024}, number={17}, journal={BIOPHYSICAL JOURNAL}, author={Galiakhmetov, Azamat R. and Davern, Carolynn M. and Esteves, Richard J. A. and Awosanya, Emmanuel O. and Guthrie, Quibria A. E. and Proulx, Caroline and Nevzorov, Alexander A.}, year={2022}, month={Sep}, pages={3263–3270} } @article{bowles_proulx_2022, title={Late-Stage N-Alkylation of Azapeptides}, volume={24}, ISSN={["1523-7052"]}, DOI={10.1021/acs.orglett.2c00046}, number={9}, journal={ORGANIC LETTERS}, author={Bowles, Maxwell O. and Proulx, Caroline}, year={2022}, month={Mar}, pages={1768–1773} } @article{young_proulx_2022, title={On-resin C alpha-functionalization of N-arylglycinyl peptides with boronic acids}, volume={5}, ISSN={["1477-0539"]}, DOI={10.1039/d2ob00524g}, journal={ORGANIC & BIOMOLECULAR CHEMISTRY}, author={Young, Hailey A. and Proulx, Caroline}, year={2022}, month={May} } @article{bowles_proulx_2021, title={Solid phase submonomer azapeptide synthesis}, volume={656}, ISSN={["0076-6879"]}, DOI={10.1016/bs.mie.2021.04.020}, journal={SYNTHETIC AND ENZYMATIC MODIFICATIONS OF THE PEPTIDE BACKBONE}, author={Bowles, Maxwell and Proulx, Caroline}, year={2021}, pages={169–190} } @article{davern_lowe_rosfi_ison_proulx_2021, title={Submonomer synthesis of peptoids containing trans-inducing N-imino- and N-alkylamino-glycines}, volume={5}, ISSN={["2041-6539"]}, DOI={10.1039/d1sc00717c}, journal={CHEMICAL SCIENCE}, author={Davern, Carolynn M. and Lowe, Brandon D. and Rosfi, Adam and Ison, Elon A. and Proulx, Caroline}, year={2021}, month={May} } @article{fregeau_sarduy_elimam_esposito_mellal_menard_graca_proulx_zhang_febbraio_et al._2020, title={Atheroprotective and atheroregressive potential of azapeptide derivatives of GHRP-6 as selective CD36 ligands in apolipoprotein E-deficient mice}, volume={307}, ISSN={["1879-1484"]}, DOI={10.1016/j.atherosclerosis.2020.06.010}, journal={ATHEROSCLEROSIS}, author={Fregeau, Genevieve and Sarduy, Roger and Elimam, Hanan and Esposito, Cloe L. and Mellal, Katia and Menard, Liliane and Graca, Silas D. Leitao da and Proulx, Caroline and Zhang, Jinqiang and Febbraio, Maria and et al.}, year={2020}, month={Aug}, pages={52–62} } @article{proulx_2020, title={Catching up to nature's ribosomes}, volume={368}, ISSN={["1095-9203"]}, DOI={10.1126/science.abb9711}, number={6494}, journal={SCIENCE}, author={Proulx, Caroline}, year={2020}, month={May}, pages={941–941} } @article{young_guthrie_proulx_2020, title={N-Arylation of Amino Acid Esters to Expand Side Chain Diversity in Ketoxime Peptide Ligations}, volume={85}, ISSN={["1520-6904"]}, DOI={10.1021/acs.joc.9b02810}, number={3}, journal={JOURNAL OF ORGANIC CHEMISTRY}, author={Young, Hailey A. and Guthrie, Quibria A. E. and Proulx, Caroline}, year={2020}, month={Feb}, pages={1748–1755} } @misc{reese_shanahan_proulx_menegatti_2020, title={Peptide science: A "rule model" for new generations of peptidomimetics}, volume={102}, ISSN={["1878-7568"]}, DOI={10.1016/j.actbio.2019.10.045}, journal={ACTA BIOMATERIALIA}, author={Reese, Hannah R. and Shanahan, Calvin C. and Proulx, Caroline and Menegatti, Stefano}, year={2020}, month={Jan}, pages={35–74} } @misc{proulx_zhang_sabatino_chemtob_ong_lubell_2020, title={Synthesis and Biomedical Potential of Azapeptide Modulators of the Cluster of Differentiation 36 Receptor (CD36)}, volume={8}, ISSN={["2227-9059"]}, DOI={10.3390/biomedicines8080241}, number={8}, journal={BIOMEDICINES}, author={Proulx, Caroline and Zhang, Jinqiang and Sabatino, David and Chemtob, Sylvain and Ong, Huy and Lubell, William D.}, year={2020}, month={Aug} } @misc{proulx_2019, title={Aerobic oxidation of N-aryl peptides for catalyst-free oxime ligations}, author={Proulx, C.}, year={2019}, month={Nov} } @inproceedings{guthrie_proulx_2019, title={Aerobic oxidation of N-phenylglycinyl peptides for catalyst-free oxime ligations}, booktitle={American Chemical Society (ACS) meeting}, author={Guthrie, Q.A.E. and Proulx, C.}, year={2019}, month={Mar} } @article{mcmechen_willis_gourville_proulx_2019, title={Aza-Amino Acids Disrupt -Sheet Secondary Structures}, volume={24}, ISSN={["1420-3049"]}, url={https://www.mdpi.com/1420-3049/24/10/1919}, DOI={10.3390/molecules24101919}, number={10}, journal={MOLECULES}, author={McMechen, Michael A. and Willis, Evan L. and Gourville, Preston C. and Proulx, Caroline}, year={2019}, month={May} } @inproceedings{proulx_2019, place={Monterey, CA}, title={In situ oxidation of N-phenylglycinyl peptides for oxime bond formation at neutral pH}, booktitle={American Peptide Symposium 2019}, author={Proulx, C.}, year={2019} } @article{guthrie_young_proulx_2019, title={Ketoxime peptide ligations: oxidative couplings of alkoxyamines to N-aryl peptides}, volume={10}, ISSN={["2041-6539"]}, DOI={10.1039/c9sc04028e}, number={41}, journal={CHEMICAL SCIENCE}, author={Guthrie, Quibria A. E. and Young, Hailey A. and Proulx, Caroline}, year={2019}, month={Nov}, pages={9506–9512} } @inproceedings{proulx_2019, title={New strategies for Ketoxime peptide ligations}, booktitle={Boulder Peptide Symposium 2019}, author={Proulx, C.}, year={2019}, month={Sep} } @misc{proulx_2019, title={Oxime ligation via in situ oxidation of N-phenylglycinyl peptides}, author={Proulx, C.}, year={2019}, month={Apr} } @article{huynh_bessi_menard_piquereau_proulx_febbraio_lubell_carpentier_burelle_ong_et al._2018, title={Adiponectin has a pivotal role in the cardioprotective effect of CP-3(iv), a selective CD36 azapeptide ligand, after transient coronary artery occlusion in mice}, volume={32}, ISSN={["1530-6860"]}, DOI={10.1096/fj.201700505r}, number={2}, journal={FASEB JOURNAL}, author={Huynh, David N. and Bessi, Valerie L. and Menard, Liliane and Piquereau, Jerome and Proulx, Caroline and Febbraio, Maria and Lubell, William D. and Carpentier, Andre C. and Burelle, Yan and Ong, Huy and et al.}, year={2018}, month={Feb}, pages={807–818} } @article{battigelli_kim_dehigaspitiya_proulx_robertson_murray_rad_kirshenbaum_zuckermann_2018, title={Glycosylated Peptoid Nanosheets as a Multivalent Scaffold for Protein Recognition}, volume={12}, ISSN={1936-0851 1936-086X}, url={http://dx.doi.org/10.1021/ACSNANO.7B08018}, DOI={10.1021/ACSNANO.7B08018}, number={3}, journal={ACS Nano}, publisher={American Chemical Society (ACS)}, author={Battigelli, Alessia and Kim, Jae Hong and Dehigaspitiya, Dilani C. and Proulx, Caroline and Robertson, Ellen J. and Murray, Daniel J. and Rad, Behzad and Kirshenbaum, Kent and Zuckermann, Ronald N.}, year={2018}, month={Mar}, pages={2455–2465} } @article{guthrie_proulx_2018, title={Oxime Ligation via in situ Oxidation of N-Phenylglycinyl Peptides}, volume={20}, ISSN={["1523-7052"]}, DOI={10.1021/acs.orglett.8b00713}, number={9}, journal={ORGANIC LETTERS}, author={Guthrie, Quibria A. E. and Proulx, Caroline}, year={2018}, month={May}, pages={2564–2567} } @inproceedings{guthrie_proulx_2018, title={Oxime ligation via in situ oxidation of N-phenylglycinyl peptides}, author={Guthrie, Q.A. and Proulx, C.}, year={2018}, month={Feb} } @misc{chingle_proulx_lubell_2017, title={Azapeptide Synthesis Methods for Expanding Side-Chain Diversity for Biomedical Applications}, volume={50}, ISSN={["1520-4898"]}, DOI={10.1021/acs.accounts.7b00114}, number={7}, journal={ACCOUNTS OF CHEMICAL RESEARCH}, author={Chingle, Ramesh and Proulx, Caroline and Lubell, William D.}, year={2017}, month={Jul}, pages={1541–1556} } @article{robertson_battigelli_proulx_mannige_haxton_yun_whitelam_zuckermann_2016, title={Design, Synthesis, Assembly, and Engineering of Peptoid Nanosheets}, volume={49}, ISSN={0001-4842 1520-4898}, url={http://dx.doi.org/10.1021/ACS.ACCOUNTS.5B00439}, DOI={10.1021/ACS.ACCOUNTS.5B00439}, number={3}, journal={Accounts of Chemical Research}, publisher={American Chemical Society (ACS)}, author={Robertson, Ellen J. and Battigelli, Alessia and Proulx, Caroline and Mannige, Ranjan V. and Haxton, Thomas K. and Yun, Lisa and Whitelam, Stephen and Zuckermann, Ronald N.}, year={2016}, month={Jan}, pages={379–389} } @article{flood_proulx_robertson_battigelli_wang_schwartzberg_zuckermann_2016, title={Improved chemical and mechanical stability of peptoid nanosheets by photo-crosslinking the hydrophobic core}, volume={52}, ISSN={1359-7345 1364-548X}, url={http://dx.doi.org/10.1039/C6CC00588H}, DOI={10.1039/C6CC00588H}, abstractNote={Photo-crosslinking produced more robust nanosheets that can survive sonication, lyophilization, and other biochemical manipulations.}, number={26}, journal={Chemical Communications}, publisher={Royal Society of Chemistry (RSC)}, author={Flood, Dillon and Proulx, Caroline and Robertson, Ellen J. and Battigelli, Alessia and Wang, Shuo and Schwartzberg, Adam M. and Zuckermann, Ronald N.}, year={2016}, pages={4753–4756} } @article{robertson_proulx_su_garcia_yoo_nehls_connolly_taravati_zuckermann_2016, title={Molecular Engineering of the Peptoid Nanosheet Hydrophobic Core}, volume={32}, ISSN={0743-7463 1520-5827}, url={http://dx.doi.org/10.1021/ACS.LANGMUIR.6B02735}, DOI={10.1021/ACS.LANGMUIR.6B02735}, number={45}, journal={Langmuir}, publisher={American Chemical Society (ACS)}, author={Robertson, Ellen J. and Proulx, Caroline and Su, Jessica K. and Garcia, Rita L. and Yoo, Stan and Nehls, Eric M. and Connolly, Michael D. and Taravati, Laudann and Zuckermann, Ronald N.}, year={2016}, month={Oct}, pages={11946–11957} } @article{proulx_noë_yoo_connolly_zuckermann_2016, title={On-resin N -terminal peptoid degradation: Toward mild sequencing conditions}, volume={106}, ISSN={0006-3525}, url={http://dx.doi.org/10.1002/BIP.22884}, DOI={10.1002/BIP.22884}, number={5}, journal={Biopolymers}, publisher={Wiley}, author={Proulx, Caroline and Noë, Falko and Yoo, Stan and Connolly, Michael D. and Zuckermann, Ronald N.}, year={2016}, month={Sep}, pages={726–736} } @article{proulx_yoo_connolly_zuckermann_2015, title={Accelerated Submonomer Solid-Phase Synthesis of Peptoids Incorporating Multiple Substituted N-Aryl Glycine Monomers}, volume={80}, ISSN={0022-3263 1520-6904}, url={http://dx.doi.org/10.1021/ACS.JOC.5B01449}, DOI={10.1021/ACS.JOC.5B01449}, number={21}, journal={The Journal of Organic Chemistry}, publisher={American Chemical Society (ACS)}, author={Proulx, Caroline and Yoo, Stan and Connolly, Michael D. and Zuckermann, Ronald N.}, year={2015}, month={Aug}, pages={10490–10497} } @inproceedings{proulx_yoo_connolly_zuckermann_2015, title={Molecular Engineering of the Peptoid Nanosheet Hydrophobic Core}, author={Proulx, C. and Yoo, S. and Connolly, M.D. and Zuckermann, R.N.}, year={2015}, month={Jun} } @article{mannige_haxton_proulx_robertson_battigelli_butterfoss_zuckermann_whitelam_2015, title={Peptoid nanosheets exhibit a new secondary-structure motif}, volume={526}, ISSN={0028-0836 1476-4687}, url={http://dx.doi.org/10.1038/NATURE15363}, DOI={10.1038/NATURE15363}, number={7573}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Mannige, Ranjan V. and Haxton, Thomas K. and Proulx, Caroline and Robertson, Ellen J. and Battigelli, Alessia and Butterfoss, Glenn L. and Zuckermann, Ronald N. and Whitelam, Stephen}, year={2015}, month={Oct}, pages={415–420} } @article{proulx_lubell_2014, title={Analysis of N-amino-imidazolin-2-one peptide turn mimic 4-position substituent effects on conformation by X-ray crystallography}, volume={102}, ISSN={0006-3525}, url={http://dx.doi.org/10.1002/BIP.22327}, DOI={10.1002/BIP.22327}, number={1}, journal={Biopolymers}, publisher={Wiley}, author={Proulx, Caroline and Lubell, William D.}, year={2014}, month={Jan}, pages={7–15} } @article{robertson_olivier_qian_proulx_zuckermann_richmond_2014, title={Assembly and molecular order of two-dimensional peptoid nanosheets through the oil–water interface}, volume={111}, ISSN={0027-8424 1091-6490}, url={http://dx.doi.org/10.1073/PNAS.1414843111}, DOI={10.1073/PNAS.1414843111}, number={37}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Robertson, Ellen J. and Olivier, Gloria K. and Qian, Menglu and Proulx, Caroline and Zuckermann, Ronald N. and Richmond, Geraldine L.}, year={2014}, month={Sep}, pages={13284–13289} } @inproceedings{proulx_yoo_zuckermann_2014, title={Improvements in the Solid-Phase Synthesis of Peptoids Incorporating Weak Nucleophile Submonomers}, author={Proulx, C. and Yoo, S. and Zuckermann, R.N.}, year={2014}, month={Jun} } @inproceedings{proulx_yoo_connolly_zuckermann_2014, title={Influence of Backbone Flexibility on the Two-dimensional Assembly of Peptoid Nanosheets}, author={Proulx, C. and Yoo, S. and Connolly, M.D. and Zuckermann, R.N.}, year={2014}, month={Aug} } @inproceedings{proulx_su_yoo_olivier_garcia_connolly_mannige_haxton_whitelam_zuckermann_2014, title={Molecular Engineering of the Peptoid Nanosheet Hydrophobic Core}, author={Proulx, C. and Su, J.K. and Yoo, S. and Olivier, G.K. and Garcia, R.L. and Connolly, M.D. and Mannige, R.V. and Haxton, T.K. and Whitelam, S. and Zuckermann, R.N.}, year={2014}, month={Aug} } @inproceedings{zhang_proulx_lubell_2014, title={Multi-component Diversity-Oriented Synthesis of Aza-lysine-peptide Mimics}, author={Zhang, J. and Proulx, C. and Lubell, W.D.}, year={2014}, month={Jun} } @article{zhang_proulx_tomberg_lubell_2014, title={Multicomponent Diversity-Oriented Synthesis of Aza-Lysine-Peptide Mimics}, volume={16}, ISSN={1523-7060 1523-7052}, url={http://dx.doi.org/10.1021/OL403297V}, DOI={10.1021/OL403297V}, number={1}, journal={Organic Letters}, publisher={American Chemical Society (ACS)}, author={Zhang, Jinqiang and Proulx, Caroline and Tomberg, Anna and Lubell, William D.}, year={2014}, month={Dec}, pages={298–301} } @inbook{sun_proulx_zuckermann_2014, title={Precision Sequence Control in Bioinspired Peptoid Polymers}, ISBN={9780841230019 9780841230026}, ISSN={0097-6156 1947-5918}, url={http://dx.doi.org/10.1021/bk-2014-1170.ch003}, DOI={10.1021/bk-2014-1170.ch003}, booktitle={ACS Symposium Series}, publisher={American Chemical Society}, author={Sun, Jing and Proulx, Caroline and Zuckermann, Ronald N.}, year={2014}, month={Jan}, pages={35–53} } @article{sanii_haxton_olivier_cho_barton_proulx_whitelam_zuckermann_2014, title={Structure-Determining Step in the Hierarchical Assembly of Peptoid Nanosheets}, volume={8}, ISSN={1936-0851 1936-086X}, url={http://dx.doi.org/10.1021/NN505007U}, DOI={10.1021/NN505007U}, number={11}, journal={ACS Nano}, publisher={American Chemical Society (ACS)}, author={Sanii, Babak and Haxton, Thomas K. and Olivier, Gloria K. and Cho, Andrew and Barton, Bastian and Proulx, Caroline and Whitelam, Stephen and Zuckermann, Ronald N.}, year={2014}, month={Oct}, pages={11674–11684} } @article{proulx_picard_boeglin_pohankova_chemtob_ong_lubell_2012, title={Azapeptide Analogues of the Growth Hormone Releasing Peptide 6 as Cluster of Differentiation 36 Receptor Ligands with Reduced Affinity for the Growth Hormone Secretagogue Receptor 1a}, volume={55}, ISSN={0022-2623 1520-4804}, url={http://dx.doi.org/10.1021/jm300557t}, DOI={10.1021/jm300557t}, number={14}, journal={Journal of Medicinal Chemistry}, publisher={American Chemical Society (ACS)}, author={Proulx, Caroline and Picard, Émilie and Boeglin, Damien and Pohankova, Petra and Chemtob, Sylvain and Ong, Huy and Lubell, William D.}, year={2012}, month={Jul}, pages={6502–6511} } @article{proulx_lubell_2012, title={N-Amino-imidazolin-2-one Peptide Mimic Synthesis and Conformational Analysis}, volume={14}, ISSN={1523-7060 1523-7052}, url={http://dx.doi.org/10.1021/ol302021n}, DOI={10.1021/ol302021n}, number={17}, journal={Organic Letters}, publisher={American Chemical Society (ACS)}, author={Proulx, Caroline and Lubell, William D.}, year={2012}, month={Aug}, pages={4552–4555} } @book{lubell_ong_proulx_hopewell_beauregard_garcia-ramos_2012, title={Peptidomimetics Comprising N-Amino Cyclic Urea Residues and Uses Thereof}, number={US 61/655,682}, author={Lubell, William D. and Ong, Huy and Proulx, Caroline and Hopewell, Robert and Beauregard, Kim and Garcia-Ramos, Yésica}, year={2012}, month={Jun} } @article{garcia-ramos_proulx_lubell_2012, title={Synthesis of hydrazine and azapeptide derivatives by alkylation of carbazates and semicarbazones}, volume={90}, ISSN={0008-4042 1480-3291}, url={http://dx.doi.org/10.1139/v2012-070}, DOI={10.1139/v2012-070}, abstractNote={ Hydrazine and azapeptide analogs were synthesized effectively by alkylation of alkylidene carbazates and semicarbazones. In comparisons of benzylidene, benzhydrylidene, and fluorenylidene tert-butyl carbazates in alkylations using bases of different pKb}, number={11}, journal={Canadian Journal of Chemistry}, publisher={Canadian Science Publishing}, author={Garcia-Ramos, Yesica and Proulx, Caroline and Lubell, William D.}, year={2012}, month={Nov}, pages={985–993} } @article{proulx_sabatino_hopewell_spiegel_garcía ramos_lubell_2011, title={Azapeptides and their therapeutic potential}, volume={3}, ISSN={1756-8919 1756-8927}, url={http://dx.doi.org/10.4155/fmc.11.74}, DOI={10.4155/fmc.11.74}, abstractNote={ Azapeptides are peptide analogs in which one or more of the amino residues is replaced by a semicarbazide. This substitution of a nitrogen for the α-carbon center results in conformational restrictions, which bend the peptide about the aza-amino acid residue away from a linear geometry. The resulting azapeptide turn conformations have been observed by x-ray crystallography and spectroscopy, as well as predicted based on computational models. In biologically active peptide analogs, the aza-substitution has led to enhanced activity and selectivity as well as improved properties, such as prolonged duration of action and metabolic stability. In light of these characteristics, azapeptides have found important uses as receptor ligands, enzyme inhibitors, drugs, pro-drugs, probes and imaging agents. Recent improvements in synthetic methods for their procurement have ushered in a new era of azapeptide chemistry. This review aims to provide a historical look at the development of azapeptide science along with a focus on recent developments and perspectives on the future of this useful tool for medicinal chemistry. }, number={9}, journal={Future Medicinal Chemistry}, publisher={Future Science Ltd}, author={Proulx, Caroline and Sabatino, David and Hopewell, Robert and Spiegel, Jochen and García Ramos, Yésica and Lubell, William D.}, year={2011}, month={Jul}, pages={1139–1164} } @inproceedings{proulx_lubell_2011, title={In search of azapeptide analogs of GHRP-6 with selective affinity for the CD36 vs GHS-R1a receptor: exploiting the reactivity of semicarbazones and aza-propargyl glycine in combinatorial azapeptide synthesis}, author={Proulx, C. and Lubell, W. D.}, year={2011}, month={Jun} } @article{bolduc_lambert-lanteigne_colin_zhao_proulx_boeglin_lubell_pelletier_féthière_ong_et al._2011, title={Modified peptide monolayer binding His-tagged biomolecules for small ligand screening with SPR biosensors}, volume={136}, ISSN={0003-2654 1364-5528}, url={http://dx.doi.org/10.1039/c1an15235a}, DOI={10.1039/c1an15235a}, number={15}, journal={The Analyst}, publisher={Royal Society of Chemistry (RSC)}, author={Bolduc, Olivier R. and Lambert-Lanteigne, Patrick and Colin, Damien Y. and Zhao, Sandy Shuo and Proulx, Caroline and Boeglin, Damien and Lubell, William D. and Pelletier, Joelle N. and Féthière, James and Ong, Huy and et al.}, year={2011}, pages={3142} } @article{sabatino_proulx_pohankova_ong_lubell_2011, title={Structure–Activity Relationships of GHRP-6 Azapeptide Ligands of the CD36 Scavenger Receptor by Solid-Phase Submonomer Azapeptide Synthesis}, volume={133}, ISSN={0002-7863 1520-5126}, url={http://dx.doi.org/10.1021/ja203007u}, DOI={10.1021/ja203007u}, number={32}, journal={Journal of the American Chemical Society}, publisher={American Chemical Society (ACS)}, author={Sabatino, David and Proulx, Caroline and Pohankova, Petra and Ong, Huy and Lubell, William D.}, year={2011}, month={Aug}, pages={12493–12506} } @inproceedings{proulx_lubell_2011, place={San Diego, CA}, title={Synthesis of [Azaphenylglycine4]- and [Aza-1-phenyl-2,3-triazole-3-alanine4] Growth Hormone Releasing Peptide-6 and Comparison of their Conformations with [AzaPhe4]GHRP-6}, booktitle={Peptides: Building Bridges. Proceedings of the 22nd American Peptide Symposium}, publisher={Prompt Scientific Publishing}, author={Proulx, C. and Lubell, W.D.}, editor={Lebl, M.Editor}, year={2011}, pages={80–81} } @inproceedings{proulx_lubell_2011, title={Synthesis of substituted imidazolinones via a cationic gold(I)-mediated intramolecular cyclization}, author={Proulx, C. and Lubell, W.D.}, year={2011}, month={Jun} } @inproceedings{proulx_lubell_2011, title={Teaching haemoglobin to third graders}, author={Proulx, C. and Lubell, W.D.}, year={2011}, month={Jun} } @inproceedings{proulx_lubell_2011, title={Tuning the selectivity of GHRP-6 towards the CD36 vs GHS-R1a receptor by exploiting the reactivity of semicarbazones and aza-propargyl glycine in combinatorial azapeptide synthesis}, author={Proulx, C. and Lubell, W. D.}, year={2011}, month={Jun} } @article{proulx_lubell_2010, title={Aza-1,2,3-triazole-3-alanine Synthesis via Copper-Catalyzed 1,3-Dipolar Cycloaddition on Aza-progargylglycine}, volume={75}, ISSN={0022-3263 1520-6904}, url={http://dx.doi.org/10.1021/jo100957z}, DOI={10.1021/jo100957z}, number={15}, journal={The Journal of Organic Chemistry}, publisher={American Chemical Society (ACS)}, author={Proulx, Caroline and Lubell, William D.}, year={2010}, month={Aug}, pages={5385–5387} } @article{proulx_lubell_2010, title={Copper-Catalyzed N-Arylation of Semicarbazones for the Synthesis of Aza-Arylglycine-Containing Aza-Peptides}, volume={12}, ISSN={1523-7060 1523-7052}, url={http://dx.doi.org/10.1021/ol100932m}, DOI={10.1021/ol100932m}, number={13}, journal={Organic Letters}, publisher={American Chemical Society (ACS)}, author={Proulx, Caroline and Lubell, William D.}, year={2010}, month={Jul}, pages={2916–2919} } @inproceedings{proulx_lubell_2010, title={Copper-catalyzed N-arylation of a semicarbazone building block for the parallel synthesis of aryl-azaglycine containing azapeptides}, author={Proulx, C. and Lubell, W.D.}, year={2010}, month={May} } @inproceedings{proulx_lubell_2010, title={Copper-catalyzed N-arylation of semicarbazones for the synthesis of aza-arylglycine containing aza-peptides}, author={Proulx, C. and Lubell, W.D.}, year={2010}, month={Mar} } @article{bourguet_proulx_klocek_sabatino_lubell_2010, title={Solution-phase submonomer diversification of aza-dipeptide building blocks and their application in aza-peptide and aza-DKP synthesis}, volume={16}, ISSN={1075-2617 1099-1387}, url={http://dx.doi.org/10.1002/psc.1235}, DOI={10.1002/psc.1235}, number={6}, journal={Journal of Peptide Science}, publisher={Wiley}, author={Bourguet, Carine B. and Proulx, Caroline and Klocek, Sophie and Sabatino, David and Lubell, William D.}, year={2010}, month={Jun}, pages={284–296} } @inproceedings{proulx_boeglin_chemtob_ong_lubell_2009, title={Aza-peptide analogs of GHRP-6 with selective receptor affinity for CD36 versus GHS-R1a”}, author={Proulx, C. and Boeglin, D. and Chemtob, S. and Ong, H. and Lubell, W.D.}, year={2009}, month={Jun} } @inproceedings{proulx_lubell_2009, title={Cu(I)-catalyzed N-arylation of semicarbazones for the synthesis of aryl-aza glycine containing azapeptides}, author={Proulx, C. and Lubell, W.D.}, year={2009}, month={Oct} } @article{sabatino_proulx_klocek_bourguet_boeglin_ong_lubell_2009, title={Exploring Side-Chain Diversity by Submonomer Solid-Phase Aza-Peptide Synthesis}, volume={11}, ISSN={1523-7060 1523-7052}, url={http://dx.doi.org/10.1021/ol901423c}, DOI={10.1021/ol901423c}, number={16}, journal={Organic Letters}, publisher={American Chemical Society (ACS)}, author={Sabatino, David and Proulx, Caroline and Klocek, Sophie and Bourguet, Carine B. and Boeglin, Damien and Ong, Huy and Lubell, William D.}, year={2009}, month={Aug}, pages={3650–3653} } @inbook{proulx_lubell_2009, place={Hoboken, N.J.}, edition={2nd}, title={O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N’,N’-tetramethyluronium tetrafluoroborate}, ISBN={9780470017548}, booktitle={Encyclopedia of Reagents for Organic Synthesis}, publisher={John Wiley & Sons Ltd}, author={Proulx, C. and Lubell, W.D.}, editor={Paquette, Leo A.Editor}, year={2009} } @inbook{proulx_lubell_2009, place={Chichester}, edition={2nd}, title={O-(6-Chloro-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate}, booktitle={Encyclopedia of Reagents for Organic Synthesis}, publisher={John Wiley & Sons Ltd}, author={Proulx, C. and Lubell, W. D.}, editor={Paquette, Leo A.Editor}, year={2009} } @inbook{proulx_lubell_2009, place={San Diego, CA}, title={Solid-Phase Synthesis of Aza-Proline Analogs of GHRP-6}, booktitle={Peptides: Breaking Away. Proceedings of the 21st American Peptide Symposium}, publisher={Prompt Scientific Publishing}, author={Proulx, C. and Lubell, W.D.}, editor={Lebl, M.Editor}, year={2009}, pages={56–57} } @inproceedings{proulx_boeglin_chemtob_ong_lubell_2008, title={Aza-peptide analogs of GHRP-6 with selective receptor affinity for CD36 versus GHS-R1a”}, author={Proulx, C. and Boeglin, D. and Chemtob, S. and Ong, H. and Lubell, W.D.}, year={2008}, month={Aug} } @book{ong_chemtob_lubell_boeglin_proulx_sabatino_sajjadi_2008, title={Azapeptides as CD36 Binding Compounds}, number={PCT/CA2008/001162}, author={Ong, Huy and Chemtob, Sylvain and Lubell, William D. and Boeglin, Damien and Proulx, Caroline and Sabatino, David and Sajjadi, Zohreh}, year={2008}, month={Jun} } @inproceedings{proulx_boeglin_chemtob_ong_lubell_2008, title={Elucidation of structural and conformational requirements for GHRP-6 binding to the GHSR-1a and CD36 receptors using aza-peptides}, author={Proulx, C. and Boeglin, D. and Chemtob, S. and Ong, H. and Lubell, W.D.}, year={2008}, month={Nov} }