Christopher Paul Smith

Works (8)

Updated: April 5th, 2024 05:11

2018 journal article

Improving wood properties for wood utilization through multi-omics integration in lignin biosynthesis

Nature Communications, 9(1), 1579.

By: J. Wang n , M. Matthews  n, C. Williams n , R. Shi n, C. Yang  n, S. Tunlaya-Anukit  n, H. Chen n, Q. Li * ...

Contributors: J. Wang n , M. Matthews  n, C. Williams n , R. Shi n, C. Yang  n, S. Tunlaya-Anukit  n, H. Chen n, Q. Li * ...

MeSH headings : Gene Expression Regulation, Plant; Lignin / biosynthesis; Lignin / genetics; Plants, Genetically Modified / genetics; Populus / genetics; Populus / metabolism; Transcriptome / genetics; Trees / genetics; Trees / metabolism; Wood / chemistry; Wood / physiology; Xylem / metabolism
TL;DR: A multi-omics quantitative integrative analysis of lignin biosynthesis can advance the strategic engineering of wood for timber, pulp, and biofuels and may lead to greater understanding of other pathways for improved growth and adaptation. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

On the substructure controls in rare variant analysis: Principal components or variance components?

GENETIC EPIDEMIOLOGY, 42(3), 276–287.

By: Y. Luo  n, A. Maity n , M. Wu *, C. Smith n, Q. Duan *, Y. Li*, J. Tzeng n

Contributors: Y. Luo  n, A. Maity n , M. Wu *, C. Smith n, Q. Duan *, Y. Li*, J. Tzeng n

author keywords: population substructure; principal components analysis; rare variant association tests; variance components
MeSH headings : Computer Simulation; Confounding Factors, Epidemiologic; Genetic Association Studies; Genetic Variation; Humans; Models, Genetic; Principal Component Analysis
TL;DR: Evaluating the performance of SKAT coupling with principal components (PC) or variance components (VC) based PS correction methods found that PC‐based methods can account for confounding effects in most scenarios except for admixture, although the number of sufficient PCs depends on the PS complexity and the type of variants used. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: Effects of estradiol and progesterone addback

Translational Psychiatry, 7.

By: T. Nguyen, J. Reuter, N. Gaikwad, D. Rotroff, H. Kucera, A. Motsinger-Reif, C. Smith, L. Nieman ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

A transcriptome-based genetic map of Chinese chestnut (Castanea mollissima) and identification of regions of segmental homology with peach (Prunus persica)

Tree Genetics & Genomes, 9(2), 557–571.

By: T. Kubisiak*, C. Nelson *, M. Staton *, T. Zhebentyayeva *, C. Smith n, B. Olukolu*, G. Fang*, F. Hebard* ...

author keywords: Fagaceae; Castanea spp.; Chestnut; Genetic map; Comparative genomics; Disease resistance
TL;DR: A highly informative genetic map was constructed to extend genomic studies in the Fagaceae and to aid the introgression of Chinese chestnut blight resistance genes into American chestnut. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2010 journal article

Genomic hotspots for adaptation: The population genetics of Mullerian mimicry in Heliconius erato

PLoS Genetics, 6(4).

By: B. Counterman, F. Araujo-Perez, H. Hines, S. Baxter, C. Morrison, D. Lindstrom, R. Papa, L. Ferguson ...

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Comparison of the transcriptomes of American chestnut (Castanea dentata) and Chinese chestnut (Castanea mollissima) in response to the chestnut blight infection

BMC PLANT BIOLOGY, 9.

By: A. Barakat*, D. DiLoreto*, Y. Zhang *, C. Smith n, K. Baier*, W. Powell *, N. Wheeler n, R. Sederoff n, J. Carlson *

MeSH headings : Ascomycota; DNA, Complementary / genetics; Expressed Sequence Tags; Fagaceae / genetics; Fagaceae / microbiology; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Library; Genes, Plant; Genomics; Plant Diseases / genetics; RNA, Plant / genetics; Sequence Analysis, DNA
TL;DR: This study sequenced the transcriptome from fungal infected and healthy stem tissues collected from blight-sensitive American chestnut and blight-resistant Chinese chestnut trees using ultra high throughput pyrosequencing to identify genes involved in resistance to Cryphonectria parasitica, resulting in the identification of a large set of cDNA unigenes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Does strong linkage disequilibrium guarantee redundant association results?

Genetic Epidemiology, 32(6), 546–552.

By: D. Nielsen n , S. Suchindran n & C. Smith n

author keywords: linkage disequilibrium; association mapping; negative correlation; case control; transmission disequilibrium
MeSH headings : Computer Simulation; Gene Frequency; Genetic Markers; Genome, Human; Haplotypes; Humans; Linkage Disequilibrium; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable
TL;DR: This work finds that in the null hypothesis situation, where there is no association between the markers and the phenotype, the relationship between LD and the correlation between association test outcomes is clear, though it is not always ideal. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2007 journal article

Comprehensive Transcriptome Profiling in Tomato Reveals a Role for Glycosyltransferase in Mi-Mediated Nematode Resistance

Plant Physiology, 144(2), 1079–1092.

By: J. Schaff n, D. Nielsen n , C. Smith n, E. Scholl n & D. Bird n 

Contributors: J. Schaff n, D. Nielsen n , C. Smith n, E. Scholl n & D. Bird  n

MeSH headings : Animals; Feeding Behavior / physiology; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Silencing; Genomics; Glycosyltransferases / metabolism; Host-Parasite Interactions / physiology; Solanum lycopersicum / enzymology; Solanum lycopersicum / genetics; Solanum lycopersicum / parasitology; Oligonucleotide Array Sequence Analysis; Plant Roots / enzymology; Plant Roots / metabolism; Plant Roots / parasitology; Reproduction / physiology; Tylenchoidea / physiology
TL;DR: The root transcriptome of the resistant and susceptible cultivars ‘Motelle’ and ‘Moneymaker’ is interrogated, providing a picture of global gene expression changes in roots during compatible and incompatible associations with RKN, and point to candidates for further investigation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

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