Cecilia Renee Schaaf

College of Veterinary Medicine

Works (6)

Updated: June 20th, 2023 22:02

2023 journal article

A LGR5 reporter pig model closely resembles human intestine for improved study of stem cells in disease

FASEB JOURNAL, 37(6).

By: C. Schaaf n, K. Polkoff n, A. Carter n, A. Stewart n, B. Sheahan n, J. Freund n, J. Ginzel*, J. Snyder* ...

author keywords: APC mutation; colorectal cancer; intestine; Lgr5; porcine; stem cell; transgenic large animal
MeSH headings : Humans; Swine; Animals; Mice; In Situ Hybridization, Fluorescence; Intestines; Stem Cells; Ileum; Colon; Coleoptera; Green Fluorescent Proteins / genetics; Receptors, G-Protein-Coupled / genetics
Sources: Web Of Science, ORCID
Added: June 12, 2023

2023 article

Changes in equine intestinal stem/progenitor cell number at resection margins in cases of small intestinal strangulation

Veerasammy, B., Gonzalez, G., Baez-Ramos, P., Schaaf, C. R., Stewart, A. S., Ludwig, E. K., … Gonzalez, L. M. (2023, February 9). EQUINE VETERINARY JOURNAL, Vol. 2.

By: B. Veerasammy n, G. Gonzalez n, P. Baez-Ramos n, C. Schaaf n, A. Stewart n, E. Ludwig n, C. McKinney-Aguirre n, J. Freund n, J. Robertson n, L. Gonzalez n

author keywords: horse; immunofluorescence; intestine; Ki67; small intestinal strangulation; stem cell
Sources: Web Of Science, ORCID
Added: January 31, 2023

2022 journal article

Culture of equine intestinal epithelial stem cells after delayed tissue storage for future applications

BMC VETERINARY RESEARCH, 18(1).

By: A. Stewart n, C. Schaaf n, B. Veerasammy n, J. Freund n & L. Gonzalez n

author keywords: Horse; Stem cell; 3D culture; Organoid; Enteroid; Intestine; Storage
MeSH headings : Animals; Cryopreservation / veterinary; Epithelial Cells / cytology; Horses; Intestines / cytology; Stem Cells / cytology; Time Factors; Cells, Cultured; Intestinal Diseases / therapy; Intestinal Diseases / veterinary
Sources: Web Of Science, ORCID
Added: January 30, 2023

2022 journal article

Orthotopic Transplantation of the Full-length Porcine Intestine After Normothermic Machine Perfusion

TRANSPLANTATION DIRECT, 8(11).

By: N. Abraham*, E. Ludwig n, C. Schaaf n, B. Veerasammy n, A. Stewart n, C. McKinney n, J. Freund n, J. Brassil ...

Sources: Web Of Science, ORCID
Added: October 31, 2022

2022 review

Use of Translational, Genetically Modified Porcine Models to Ultimately Improve Intestinal Disease Treatment

[Review of ]. FRONTIERS IN VETERINARY SCIENCE, 9.

By: C. Schaaf n & L. Gonzalez n

author keywords: cystic fibrosis; colorectal cancer; ischemia-reperfusion injury; genetically altered models; intestinal disease; translational porcine model; stem cell reporter model
Sources: Web Of Science, ORCID
Added: June 13, 2022

2021 journal article

HOPX+ injury-resistant intestinal stem cells drive epithelial recovery after severe intestinal ischemia

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 321(5), G588–G602.

By: A. Stewart n, C. Schaaf n, J. Luff n, J. Freund n, T. Becker*, S. Tufts n, J. Robertson n, L. Gonzalez n

author keywords: epithelial repair; HOPX; ischemia; large animal models; stem cell
MeSH headings : Animals; Cell Proliferation; Disease Models, Animal; Epithelial Cells / metabolism; Epithelial Cells / pathology; Female; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Intestinal Mucosa / metabolism; Intestinal Mucosa / pathology; Male; Mesenteric Ischemia / genetics; Mesenteric Ischemia / metabolism; Mesenteric Ischemia / pathology; Phenotype; Re-Epithelialization; Severity of Illness Index; Stem Cells / metabolism; Stem Cells / pathology; Sus scrofa; Tissue Culture Techniques
Sources: Web Of Science, ORCID
Added: November 3, 2021