Constanza Meneses

College of Veterinary Medicine

Works (3)

Updated: July 5th, 2023 14:43

2023 journal article

Acute radiotherapy-associated oral pain may promote tumor growth at distant sites

FRONTIERS IN ONCOLOGY, 13.

By: C. Meneses n, E. Gidcumb  n, K. Marcus n, Y. Gonzalez n, Y. Lai n , S. Mishra n, B. Lascelles  n, M. Nolan n 

author keywords: pain; radiotherapy; sensory nerves; cancer; mouse; TRPV1
TL;DR: This research points towards radiation-induced activation of capsaicin-responsive (TRPV1) neurons as the cause for accelerated growth of tumors at distant (unirradiated) sites. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 12, 2023

2021 journal article

Irradiation of the Normal Murine Tongue Causes Upregulation and Activation of Transient Receptor Potential (TRP) Ion Channels

RADIATION RESEARCH, 196(4), 331–344.

By: Y. Lai* , W. Baumer, C. Meneses*, D. Roback*, J. Robertson* , S. Mishra n, B. Lascelles *, M. Nolan n 

MeSH headings : Animals; Calcium; Female; Mice; Neurons; Transient Receptor Potential Channels; Trigeminal Ganglion; Up-Regulation
TL;DR: The results intimate that various TRP channels, and TRPV1 in particular, should be explored as analgesic targets for patients experiencing pain after oral irradiation. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 18, 2021

2020 journal article

Proteomic profiling of proteins in the dorsal horn of the spinal cord in dairy cows with chronic lameness

PLOS ONE, 15(1).

By: D. Herzberg *, P. Strobel*, H. Muller*, C. Meneses n, M. Werner* & H. Bustamante *

MeSH headings : Animals; Cattle; Cattle Diseases / genetics; Cattle Diseases / metabolism; Cattle Diseases / physiopathology; Chronic Pain / genetics; Chronic Pain / metabolism; Chronic Pain / physiopathology; Chronic Pain / veterinary; Dairying; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Gene Regulatory Networks; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Isoenzymes / genetics; Isoenzymes / metabolism; Lactation / physiology; Lameness, Animal / genetics; Lameness, Animal / metabolism; Lameness, Animal / physiopathology; Molecular Sequence Annotation; Myelin Basic Protein / genetics; Myelin Basic Protein / metabolism; Nerve Tissue Proteins / classification; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Phosphopyruvate Hydratase / genetics; Phosphopyruvate Hydratase / metabolism; Proteomics / methods; Spinal Cord Dorsal Horn / metabolism; Spinal Cord Dorsal Horn / physiopathology
TL;DR: Chronic inflammatory lameness in cows is associated to increased expression of stress proteins with chaperone, metabolism, redox and structural functions and a state of endoplasmic reticulum stress and unfolded protein response might explain the changes in protein expression in lame cows. (via Semantic Scholar)
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Source: Web Of Science
Added: June 15, 2020

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