Constanza Meneses

College of Veterinary Medicine

Works (3)

Updated: July 5th, 2023 14:43

2023 journal article

Acute radiotherapy-associated oral pain may promote tumor growth at distant sites

FRONTIERS IN ONCOLOGY, 13.

By: C. Meneses n, E. Gidcumb n, K. Marcus n, Y. Gonzalez  n, Y. Lai n, S. Mishra n, B. Lascelles  n, M. Nolan n

author keywords: pain; radiotherapy; sensory nerves; cancer; mouse; TRPV1
TL;DR: This research points towards radiation-induced activation of capsaicin-responsive (TRPV1) neurons as the cause for accelerated growth of tumors at distant (unirradiated) sites. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: June 12, 2023

2021 journal article

Irradiation of the Normal Murine Tongue Causes Upregulation and Activation of Transient Receptor Potential (TRP) Ion Channels

RADIATION RESEARCH, 196(4), 331–344.

By: Y. Lai, W. Baumer, C. Meneses*, D. Roback*, J. Robertson* , S. Mishra n, B. Lascelles *, M. Nolan n

MeSH headings : Animals; Calcium; Female; Mice; Neurons; Transient Receptor Potential Channels; Trigeminal Ganglion; Up-Regulation
TL;DR: The results intimate that various TRP channels, and TRPV1 in particular, should be explored as analgesic targets for patients experiencing pain after oral irradiation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: October 18, 2021

2020 journal article

Proteomic profiling of proteins in the dorsal horn of the spinal cord in dairy cows with chronic lameness

PLOS ONE, 15(1).

By: D. Herzberg*, P. Strobel*, H. Muller*, C. Meneses n, M. Werner* & H. Bustamante*

MeSH headings : Animals; Cattle; Cattle Diseases / genetics; Cattle Diseases / metabolism; Cattle Diseases / physiopathology; Chronic Pain / genetics; Chronic Pain / metabolism; Chronic Pain / physiopathology; Chronic Pain / veterinary; Dairying; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Gene Regulatory Networks; Heat-Shock Proteins / genetics; Heat-Shock Proteins / metabolism; Isoenzymes / genetics; Isoenzymes / metabolism; Lactation / physiology; Lameness, Animal / genetics; Lameness, Animal / metabolism; Lameness, Animal / physiopathology; Molecular Sequence Annotation; Myelin Basic Protein / genetics; Myelin Basic Protein / metabolism; Nerve Tissue Proteins / classification; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Phosphopyruvate Hydratase / genetics; Phosphopyruvate Hydratase / metabolism; Proteomics / methods; Spinal Cord Dorsal Horn / metabolism; Spinal Cord Dorsal Horn / physiopathology
TL;DR: Chronic inflammatory lameness in cows is associated to increased expression of stress proteins with chaperone, metabolism, redox and structural functions and a state of endoplasmic reticulum stress and unfolded protein response might explain the changes in protein expression in lame cows. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 15, 2020

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