2022 journal article

Polymer Nanoparticles Enhance Irreversible Electroporation In Vitro

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 69(7), 2353–2362.

By: R. Petrella n, S. Levit*, C. Fesmire n, C. Tang* & M. Sano n

author keywords: Nanoparticles; Electric fields; Electroporation; Media; Polymers; Electrodes; Tumors; Irreversible electroporation; pulsed electric fields; tumor ablation; oncology; nanoparticle; nanobiotechnology; flash nanoprecipitation; polyelectrolyte
MeSH headings : Ablation Techniques; Electric Conductivity; Electroporation / methods; Nanoparticles; Polymers
TL;DR: Results demonstrate the synergy of a combined cationic polymer nanoparticle and pulsed electric field treatment for the ablation of cancer cells, and set the foundation for polymer nanoparticles engineered specifically for irreversible electroporation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 11, 2022

2014 journal article

Cross-linked Polymer Nanofibers for Hyperthermophilic Enzyme Immobilization: Approaches to Improve Enzyme Performance

ACS APPLIED MATERIALS & INTERFACES, 6(15), 11899–11906.

By: C. Tang n, C. Saquing n, S. Morton n, B. Glatz n, R. Kelly n & S. Khan n

author keywords: enzyme immobilization; nanofibers; electrospinning; biocatalysts; mass transfer
MeSH headings : Catalysis; Cross-Linking Reagents / chemistry; Electrochemistry; Enzymes, Immobilized / chemistry; Escherichia coli / metabolism; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Nanofibers / chemistry; Nanotechnology / methods; Polymers / chemistry; Polyvinyl Alcohol / chemistry; Solvents / chemistry; Temperature; Thermotoga maritima / metabolism
TL;DR: An enzyme immobilization method effective at elevated temperatures (up to 105 °C) and sufficiently robust for hyperthermophilic enzymes is reported and Improvements in the apparent activity can be achieved by incorporating a cryoprotectant during immobilization to prevent enzyme deactivation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Electrospinning and heat treatment of whey protein nanofibers

FOOD HYDROCOLLOIDS, 35, 36–50.

By: S. Sullivan n, C. Tang n, A. Kennedy*, S. Talwar n & S. Khan n

author keywords: Whey protein; Nanofiber; Crosslinking; Electrospinning
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Nanofibrous membranes for single-step immobilization of hyperthermophilic enzymes

JOURNAL OF MEMBRANE SCIENCE, 472, 251–260.

By: C. Tang n, C. Saquing n, P. Sarin n, R. Kelly n & S. Khan n

author keywords: Enzyme immobilization; Nanofibers; Electrospinning; Chemical crosslinking; Hyperthermophilic enzymes
TL;DR: Analysis of this immobilization method indicates that the apparent decrease in specific activity could be attributed to enzyme deactivation arising from the crosslinking reaction, whereas mass transfer limits the apparent activity using alternative two-step immobilization methods. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Preservation of Cell Viability and Protein Conformation on Immobilization within Nanofibers via Electrospinning Functionalized Yeast

ACS APPLIED MATERIALS & INTERFACES, 5(19), 9349–9354.

By: M. Canbolat n, N. Gera n, C. Tang n, B. Monian n, B. Rao n, B. Pourdeyhimi n, S. Khan n

author keywords: electrospinning; nanofiber; protein; biocatalyst immobilization; yeast surface display
MeSH headings : Biocatalysis; Cell Survival / drug effects; Green Fluorescent Proteins; Microscopy, Electron, Scanning; Nanofibers / chemistry; Polymers / chemistry; Polymers / pharmacology; Polyvinyl Alcohol / chemistry; Polyvinyl Alcohol / pharmacology; Protein Conformation / drug effects; Saccharomyces cerevisiae / chemistry; Saccharomyces cerevisiae / drug effects; Saccharomyces cerevisiae / growth & development; Water / chemistry
TL;DR: This method of processing functionalized yeast may be a powerful tool in the direct immobilization of properly folded, active enzymes within electrospun nanofibers with potential applications in biocatalysis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Mammalian Cell Viability in Electrospun Composite Nanofiber Structures

MACROMOLECULAR BIOSCIENCE, 11(10), 1346–1356.

By: M. Canbolat n, C. Tang n, S. Bernacki n, B. Pourdeyhimi n & S. Khan n

author keywords: 3T3-L1 mice fibroblasts; electrospinning; nanofibers; fibers; nanotechnology; tissue engineering; viability
MeSH headings : 3T3-L1 Cells; Animals; Cell Adhesion / drug effects; Cell Death / drug effects; Cell Survival / drug effects; Fibroblasts / cytology; Fibroblasts / ultrastructure; Mammals / metabolism; Mice; Nanocomposites / chemistry; Nanocomposites / ultrastructure; Nanofibers / chemistry; Nanofibers / ultrastructure; Polyesters / pharmacology; Polyvinyl Alcohol / pharmacology; Solutions; Solvents; Time Factors; Tissue Engineering / methods
TL;DR: It is observed that cells do not survive cell electrospinning but survive cell layering, and dehydration and fiber stretching are the main causes of cell death. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

journal article

Alginate-polyethylene oxide blend nanofibers and the role of the carrier polymer in electrospinning

Saquing, C. D., Tang, C., Monian, B., Bonino, C. A., Manasco, J. L., Alsberg, E., & Khan, S. A. Industrial & Engineering Chemistry Research, 52(26), 8692–8704.

By: C. Saquing, C. Tang, B. Monian, C. Bonino, J. Manasco, E. Alsberg, S. Khan

Source: NC State University Libraries
Added: August 6, 2018

journal article

Cyclodextrin fibers via polymer-free electrospinning

Manasco, J. L., Saquing, C. D., Tang, C., & Khan, S. A. RSC Advances, 2(9), 3778–3784.

By: J. Manasco, C. Saquing, C. Tang & S. Khan

Source: NC State University Libraries
Added: August 6, 2018

journal article

Effect of pH on protein distribution in electrospun PVA/BSA composite nanofibers

Tang, C., Ozcam, A. E., Stout, B., & Khan, S. A. Biomacromolecules, 13(5), 1269–1278.

By: C. Tang, A. Ozcam, B. Stout & S. Khan

Source: NC State University Libraries
Added: August 6, 2018

journal article

Foam electrospinning: A multiple jet, needle-less process for nanofiber production

Higham, A. K., Tang, C., Landry, A. M., Pridgeon, M. C., Lee, E. M., Andrady, A. L., & Khan, S. A. AIChE Journal, 60(4), 1355–1364.

By: A. Higham, C. Tang, A. Landry, M. Pridgeon, E. Lee, A. Andrady, S. Khan

Source: NC State University Libraries
Added: August 6, 2018

journal article

Rapidly dissolving poly(vinyl alcohol)/cyclodextrin electrospun nanofibrous membranes

Manasco, J. L., Tang, C., Burns, N. A., Saquing, C. D., & Khan, S. A. RSC Advances, 4(26), 13274–13279.

By: J. Manasco, C. Tang, N. Burns, C. Saquing & S. Khan

Source: NC State University Libraries
Added: August 6, 2018

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