Christopher Moody
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Works (6)
Updated: July 29th, 2023 21:14
2023 journal article
Loading Intracranial Drug-Eluting Reservoirs Across the Blood-Brain Barrier With Focused Ultrasound
ULTRASOUND IN MEDICINE AND BIOLOGY, 49(7), 1679–1685.
author keywords: Blood-brain barrier; Brain delivery; Click chemistry; Drug delivery; Focused ultrasound
MeSH headings : Female; Mice; Animals; Blood-Brain Barrier; Drug Delivery Systems / methods; Neurodegenerative Diseases; Brain / diagnostic imaging; Microbubbles; Magnetic Resonance Imaging / methods
Sources: Web Of Science, ORCID
Added: June 19, 2023
2022 journal article
Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture
ACTA BIOMATERIALIA, 138, 208–217.
author keywords: Alginate; Click chemistry; Bioconjugation; Ionic cross-linking; Drug capture
Sources: Web Of Science, ORCID
Added: October 31, 2021
2021 journal article
On-Demand Drug Release from Click-Refillable Drug Depots
MOLECULAR PHARMACEUTICS, 18(10), 3920–3925.
author keywords: drug delivery; bioorthogonal; stimuli-responsive; photocleavage; click chemistry
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Cell Line, Tumor; Click Chemistry / methods; Delayed-Action Preparations; Doxorubicin / administration & dosage; Doxorubicin / pharmacokinetics; Drug Delivery Systems / methods; Drug Liberation; Fluorescent Dyes; Humans; Mice
www.ncbi.nlm.nih.gov (repository)
Sources: Web Of Science, ORCID
Added: October 26, 2021
2020 journal article
In Vivo Targeting Using Arylboronate/Nopoldiol Click Conjugation
BIOCONJUGATE CHEMISTRY, 31(10), 2288–2292.
MeSH headings : Animals; Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Click Chemistry / methods; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Semicarbazides / chemical synthesis; Semicarbazides / chemistry
Sources: Web Of Science, ORCID
Added: December 21, 2020
2019 journal article
Extracellular-Matrix-Anchored Click Motifs for Specific Tissue Targeting
Molecular Pharmaceutics, 17(2), 392–403.
author keywords: drug delivery; click chemistry; pancreatic cancer; brain delivery; extracellular matrix; computer modeling
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Brain / metabolism; Cell Line, Tumor; Click Chemistry / methods; Computational Biology / methods; Computer Simulation; Disease Models, Animal; Drug Delivery Systems / methods; Esters / administration & dosage; Esters / chemistry; Esters / pharmacokinetics; Extracellular Matrix / drug effects; Female; Hydrogels / administration & dosage; Mice; Mice, Inbred C57BL; Pancreatic Neoplasms / drug therapy; Pancreatic Neoplasms / pathology; Succinimides; Tissue Distribution
Sources: Web Of Science, ORCID, Crossref
Added: April 20, 2020
2018 journal article
Replenishable drug depot to combat post-resection cancer recurrence
BIOMATERIALS, 178, 373–382.
author keywords: Biomaterials; Drug delivery; Cancer therapy; Drug depot; Sustained release
MeSH headings : Alginates / chemistry; Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Cell Line, Tumor; Cell Proliferation / drug effects; Click Chemistry; Doxorubicin / chemistry; Doxorubicin / pharmacology; Doxorubicin / therapeutic use; Female; Hydrogels / chemistry; Kinetics; Mice; Neoplasm Recurrence, Local / drug therapy; Neoplasm Recurrence, Local / pathology; Neoplasms / pathology; Neoplasms / surgery; Prodrugs / chemical synthesis; Prodrugs / pharmacology; Prodrugs / therapeutic use; Prodrugs / toxicity; Subcutaneous Tissue / drug effects
Sources: Web Of Science, ORCID
Added: October 19, 2018
