Christian Woelfel

Works (6)

Updated: July 29th, 2023 21:16

2023 article

Presumed pituitary apoplexy in 26 dogs: Clinical findings, treatments, and outcomes

Woelfel, C. W., Mariani, C. L., Nolan, M. W., Keenihan, E. K., Topulos, S. P., Early, P. J., … Olby, N. J. (2023, April 21). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 4.

By: C. Woelfel n, C. Mariani n , M. Nolan n, E. Keenihan n, S. Topulos n, P. Early n, K. Munana n , S. Musulin n , N. Olby n 

author keywords: adenoma; carcinoma; endocrionopathy; hemorrhage; magnetic resonance imaging; suprasellar; survival
MeSH headings : Dogs; Animals; Pituitary Apoplexy / therapy; Pituitary Apoplexy / veterinary; Pituitary Apoplexy / diagnosis; Pituitary Neoplasms / complications; Pituitary Neoplasms / diagnostic imaging; Pituitary Neoplasms / therapy; Pituitary Neoplasms / veterinary; Retrospective Studies; Hydrocephalus / veterinary; Infarction / veterinary; Magnetic Resonance Imaging / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / therapy
TL;DR: Dogs with pituitary apoplexy present with a variety of acute signs of neurological disease and inconsistent endocrine dysfunction and dogs that survive to discharge can have a favorable outcome. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 22, 2023

2022 article

A novel mutation of the CLCN1 gene in a cat with myotonia congenita: Diagnosis and treatment

Woelfel, C., Meurs, K., Friedenberg, S., DeBruyne, N., & Olby, N. J. (2022, July 11). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 7.

By: C. Woelfel n, K. Meurs n , S. Friedenberg *, N. DeBruyne n & N. Olby n 

author keywords: chloride channel; electromyography; nondystrophic myotonia; phenytoin
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / genetics; Cats; Chloride Channels / genetics; Electromyography / veterinary; Exons; Male; Mutation; Myotonia Congenita / diagnosis; Myotonia Congenita / drug therapy; Myotonia Congenita / genetics; Myotonia Congenita / veterinary
TL;DR: Phenytoin treatment was initiated at 3 mg/kg po q24 h and resulted in long‐term improvement and is reported for the first time its successful treatment. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 18, 2022

2022 journal article

Novel subcutaneous cytarabine infusion with the Omnipod system in dogs with meningoencephalomyelitis of unknown etiology

AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(9).

By: S. Mancini n, P. Early n, B. Slater*, N. Olby n , C. Mariani n , K. Munana n , C. Woelfel n, J. Schacher n, L. Zhong *, K. Messenger n

MeSH headings : Animals; Area Under Curve; Chromatography, High Pressure Liquid / veterinary; Cytarabine / therapeutic use; Dogs; Half-Life; Humans; Infusions, Intravenous / veterinary; North Carolina
TL;DR: An SC continuous-rate infusion of cytarabine via the Omnipod system is feasible in dogs and was able to achieve a steady-state concentration of more than 1 μg/mL 4 to 10 hours postinitiation of cyTarabine and a Cmax of 7,510 ng/mL, comparable to values reported previously with IV continuous- rate infusion administration in healthy research Beagles and dogs with meningoencephalomyelitis of unknown etiology. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 1, 2022

2021 journal article

Association between filum terminale internum length and pain in Cavalier King Charles spaniels with and without syringomyelia

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(1), 363–371.

By: C. Sparks n, C. Woelfel n, I. Robertson n & N. Olby n 

author keywords: Chiari-like malformation; conus medullaris; dural sac; morphometry; tethered cord
MeSH headings : Animals; Cauda Equina / diagnostic imaging; Dog Diseases; Dogs; Magnetic Resonance Imaging / veterinary; Pain / veterinary; Prospective Studies; Reproducibility of Results; Syringomyelia / diagnostic imaging; Syringomyelia / veterinary
TL;DR: Painful CKCS without SM have decreased distance between the termination of the spinal cord and dural sac, suggesting a shorter FTIL, and more caudal spinal cord termination is associated with development of lumbar SM. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 1, 2021

2021 journal article

Outcomes and prognostic indicators in 59 paraplegic medium to large breed dogs with extensive epidural hemorrhage secondary to thoracolumbar disc extrusion

VETERINARY SURGERY, 50(3), 527–536.

By: C. Woelfel n, J. Robertson n , C. Mariani n , K. Munana n , P. Early n & N. Olby n 

MeSH headings : Animals; Cohort Studies; Dog Diseases / diagnosis; Dog Diseases / surgery; Dogs; Female; Hematoma, Epidural, Spinal / complications; Hematoma, Epidural, Spinal / surgery; Hematoma, Epidural, Spinal / veterinary; Intervertebral Disc Degeneration / complications; Intervertebral Disc Degeneration / surgery; Intervertebral Disc Degeneration / veterinary; Laminectomy / statistics & numerical data; Laminectomy / veterinary; Male; Paraplegia / diagnosis; Paraplegia / surgery; Paraplegia / veterinary; Prognosis; Recovery of Function; Retrospective Studies; Species Specificity; Treatment Outcome; Walking
TL;DR: Paraplegic medium to large breed dogs with DEEH have a less favorable outcome after surgical decompression than paraplegic dogs with TL-IVDE, and loss of pain perception and increased HASTEi are associated with a poor outcome, while more extensive decompression improves outcome. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: March 8, 2021

2021 article

Subaxial cervical articular process subluxation and dislocation: Cervical locked facet injuries in dogs

Woelfel, C. W., Bray, K. Y., Early, P. J., Mariani, C. L., & Olby, N. J. (2021, November 24). VETERINARY SURGERY, Vol. 11.

By: C. Woelfel n, K. Bray*, P. Early n, C. Mariani n  & N. Olby n 

MeSH headings : Animals; Cervical Vertebrae; Dogs; Joint Dislocations / veterinary; Neck; Retrospective Studies
TL;DR: In these dogs, locked facet injuries affected the caudal cervical vertebrae in small breeds and could be identified on imaging through the presence of dorsal displacement of a cranial articular process. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: December 6, 2021

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