Debra A. Tokarz
Works (24)
Updated: August 22nd, 2023 21:16
2023 journal article
Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer?s disease mouse models
JOURNAL OF CELL SCIENCE, 136(6).
co-author countries:
United States of America 🇺🇸
author keywords: Alzheimer?s disease; Cell death; Inflammation; TAK1
MeSH headings : Animals; Mice; Alzheimer Disease / genetics; Calcium; Cytokines / metabolism; Neuroinflammatory Diseases; Signal Transduction / physiology
doi.org (publisher)
Sources: Web Of Science, ORCID
Added: May 30, 2023
2022 article
Inter-pathologist agreement on diagnosis, classification and grading of canine glioma
Krane, G. A., Shockley, K. R., Malarkey, D. E., Miller, A. D., Miller, C. R., Tokarz, D. A., … Mariani, C. L. (2022, July 30). VETERINARY AND COMPARATIVE ONCOLOGY, Vol. 7.
co-author countries:
United States of America 🇺🇸
author keywords: brain; cancer; dog; histopathology; immunohistochemistry
MeSH headings : Humans; Animals; Dogs; Oligodendroglioma / diagnosis; Oligodendroglioma / veterinary; Oligodendroglioma / pathology; Pathologists; Dog Diseases / diagnosis; Dog Diseases / pathology; Glioma / diagnosis; Glioma / veterinary; Glioma / pathology; Astrocytoma / veterinary; Brain Neoplasms / diagnosis; Brain Neoplasms / veterinary; Brain Neoplasms / pathology
Sources: Web Of Science, ORCID
Added: August 8, 2022
2021 article
Immunohistochemical evaluation of immune cell infiltration in canine gliomas
Krane, G. A., Carly A. O'Dea, Malarkey, D. E., Miller, A. D., Miller, C. R., Tokarz, D. A., … Mariani, C. L. (2021, July 1). VETERINARY PATHOLOGY, Vol. 7.
co-author countries:
United States of America 🇺🇸
author keywords: astrocytoma; brain; dogs; cancer; immunohistochemistry; immunology; lymphocytes; macrophages; oligodendroglioma
MeSH headings : Animals; Antigens, CD20; Dog Diseases; Dogs; Glioma / veterinary; Immunohistochemistry; Lymphocytes, Tumor-Infiltrating; T-Lymphocytes, Regulatory
Sources: Web Of Science, ORCID
Added: August 2, 2021
2021 journal article
Personalized-induced neural stem cell therapy: Generation, transplant, and safety in a large animal model
BIOENGINEERING & TRANSLATIONAL MEDICINE, 6(1).
co-author countries:
United States of America 🇺🇸
author keywords: glioblastoma; neural stem cells; stem cell delivery
Sources: Web Of Science, ORCID
Added: August 3, 2020
2021 journal article
Scavenger Receptor BI Attenuates IL-17A-Dependent Neutrophilic Inflammation in Asthma
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 64(6), 698–708.
co-author countries:
United States of America 🇺🇸
author keywords: asthma; IL-17A; SR-BI receptor; neutrophilia; adrenal insufficiency
MeSH headings : Adrenal Insufficiency / complications; Adrenal Insufficiency / immunology; Animals; Asthma / immunology; Asthma / metabolism; Asthma / parasitology; Asthma / pathology; CD36 Antigens / deficiency; CD36 Antigens / metabolism; Hypersensitivity / complications; Inflammation / pathology; Interleukin-17 / metabolism; Lung / parasitology; Lung / pathology; Male; Mice, Inbred C57BL; Neutrophils / immunology; Neutrophils / pathology; Ovalbumin / immunology; Pyroglyphidae / physiology; Th17 Cells / immunology
Source: Web Of Science
Added: June 28, 2021
2021 journal article
Sex Differences in Pulmonary Eicosanoids and Specialized Pro-Resolving Mediators in Response to Ozone Exposure
TOXICOLOGICAL SCIENCES, 183(1), 170–183.
co-author countries:
United States of America 🇺🇸
author keywords: air pollution; lipids; lung; inflammation; sex differences
MeSH headings : Animals; Eicosanoids; Female; Lung; Male; Mice; Mice, Inbred C57BL; Ozone / toxicity; Sex Characteristics
Source: Web Of Science
Added: September 27, 2021
2020 journal article
Matrix Metalloproteinase-12 Is Required for Granuloma Progression
FRONTIERS IN IMMUNOLOGY, 11.
co-author countries:
Egypt 🇪🇬 United States of America 🇺🇸
author keywords: sarcoidosis; MMP12; PPAR gamma; MWCNT; granuloma; inflammation
MeSH headings : Animals; Granuloma / chemically induced; Granuloma / genetics; Granuloma / immunology; Granuloma / pathology; Macrophages, Alveolar / immunology; Macrophages, Alveolar / pathology; Matrix Metalloproteinase 12 / genetics; Matrix Metalloproteinase 12 / immunology; Mice; Mice, Knockout; Nanotubes, Carbon / adverse effects; Sarcoidosis, Pulmonary / chemically induced; Sarcoidosis, Pulmonary / genetics; Sarcoidosis, Pulmonary / immunology; Sarcoidosis, Pulmonary / pathology
Source: Web Of Science
Added: October 26, 2020
2019 journal article
Alveolar Macrophage ABCG1 Deficiency Promotes Pulmonary Granulomatous Inflammation
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 61(3), 332–340.
co-author countries:
United States of America 🇺🇸
author keywords: pulmonary sarcoidosis; granuloma; alveolar macrophage; lipid transporters; carbon nanotubes
MeSH headings : ATP Binding Cassette Transporter 1 / genetics; ATP Binding Cassette Transporter, Subfamily G, Member 1 / deficiency; ATP-Binding Cassette Transporters / genetics; Animals; Granuloma / metabolism; Inflammation / metabolism; Lung / metabolism; Macrophages, Alveolar / metabolism; Mice, Knockout; Pneumonia / metabolism; Sarcoidosis, Pulmonary / metabolism
Source: Web Of Science
Added: September 23, 2019
2019 journal article
Cardiac Leiomyosarcoma in a Cat Presenting for Bilateral Renal Neoplasia
JOURNAL OF COMPARATIVE PATHOLOGY, 168, 19–24.
co-author countries:
United States of America 🇺🇸
author keywords: cardiac neoplasia; cat; immunohistochemistry; leiomyosarcoma
MeSH headings : Animals; Cat Diseases / pathology; Cats; Female; Heart Neoplasms / veterinary; Kidney Neoplasms / veterinary; Leiomyosarcoma / veterinary
Source: Web Of Science
Added: June 4, 2019
2018 journal article
A de novo mutation in the EXT2 gene associated with osteochondromatosis in a litter of American Staffordshire Terriers
Journal of Veterinary Internal Medicine, 32(3), 986–992.
co-author countries:
United States of America 🇺🇸
author keywords: bone; cartilage; genetics; multiple cartilaginous exostoses; mutation; osteochondroma
MeSH headings : Animals; Cartilage / pathology; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genetic Variation / genetics; Male; Mosaicism / veterinary; N-Acetylglucosaminyltransferases / genetics; Osteochondromatosis / genetics; Osteochondromatosis / pathology; Osteochondromatosis / veterinary; Polymorphism, Single Nucleotide / genetics; Whole Genome Sequencing / veterinary
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2018 journal article
C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event
Cell Death & Disease, 9(11).
co-author countries:
United States of America 🇺🇸
Contributors: Z. Messenger*, J. Hall*, D. Jima*, J. House* , H. Tam, n, R. Smart*
MeSH headings : 9,10-Dimethyl-1,2-benzanthracene / administration & dosage; Animals; Apoptosis / drug effects; Apoptosis / genetics; CCAAT-Enhancer-Binding Protein-beta / deficiency; CCAAT-Enhancer-Binding Protein-beta / genetics; Cell Differentiation; Cell Transformation, Neoplastic / genetics; Cell Transformation, Neoplastic / metabolism; Cell Transformation, Neoplastic / pathology; Gene Expression Regulation, Neoplastic; Genes, Lethal; Keratinocytes / drug effects; Keratinocytes / metabolism; Keratinocytes / pathology; Mice; Mice, Knockout; Receptors, Death Domain / genetics; Receptors, Death Domain / metabolism; Signal Transduction; Skin / drug effects; Skin / metabolism; Skin / pathology; Skin Neoplasms / chemically induced; Skin Neoplasms / genetics; Skin Neoplasms / metabolism; Skin Neoplasms / pathology; Tetradecanoylphorbol Acetate / administration & dosage; Tetradecanoylphorbol Acetate / analogs & derivatives; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / metabolism; ras Proteins / genetics; ras Proteins / metabolism
Sources: Web Of Science, Crossref, ORCID
Added: October 29, 2018
2018 journal article
PPAR-gamma pathways attenuate pulmonary granuloma formation in a carbon nanotube induced murine model of sarcoidosis
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 503(2), 684–690.
co-author countries:
United States of America 🇺🇸
author keywords: Sarcoidosis; Granuloma; Carbon nanotube; Inflammation; Lipid transporters; Alveolar macrophage
MeSH headings : Animals; Disease Models, Animal; Dyslipidemias / etiology; Dyslipidemias / genetics; Dyslipidemias / metabolism; Dyslipidemias / pathology; Gene Expression Regulation; Granuloma / etiology; Granuloma / genetics; Granuloma / metabolism; Granuloma / pathology; Lung / metabolism; Lung / pathology; Lung Diseases / etiology; Lung Diseases / genetics; Lung Diseases / metabolism; Lung Diseases / pathology; Macrophages, Alveolar / metabolism; Macrophages, Alveolar / pathology; Mice, Inbred C57BL; Nanotubes, Carbon / adverse effects; PPAR gamma / agonists; PPAR gamma / metabolism; Sarcoidosis / etiology; Sarcoidosis / genetics; Sarcoidosis / metabolism; Sarcoidosis / pathology; Signal Transduction
Source: Web Of Science
Added: October 19, 2018
2018 journal article
Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes
NANOTOXICOLOGY, 12(9), 975–991.
co-author countries:
United States of America 🇺🇸
author keywords: Caron nanotubes; immunotoxicology; cancer; granuloma; p53
MeSH headings : Animals; Dose-Response Relationship, Drug; Granuloma, Respiratory Tract / chemically induced; Granuloma, Respiratory Tract / genetics; Granuloma, Respiratory Tract / immunology; Inhalation Exposure; Lung / drug effects; Lung / immunology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Surface Properties; Tertiary Lymphoid Structures / chemically induced; Tertiary Lymphoid Structures / genetics; Tertiary Lymphoid Structures / immunology; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / physiology
Source: Web Of Science
Added: March 4, 2019
2017 journal article
Disruption of Trim9 function abrogates macrophage motility in vivo
Journal of Leukocyte Biology, 102(6), 1371–1380.
co-author countries:
United States of America 🇺🇸
author keywords: chemotaxis; zebrafish; leukocyte; ubiquitin
MeSH headings : Animals; Cell Movement / genetics; Cell Shape; Chemotaxis; Humans; Macrophages / cytology; Macrophages / metabolism; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Tripartite Motif Proteins / genetics; Tripartite Motif Proteins / metabolism; U937 Cells; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2017 journal article
Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling
Development, 144(16), 2925–2939.
co-author countries:
United Arab Emirates 🇦🇪 United States of America 🇺🇸
author keywords: Transposon; DNA methylation; Uhrf1; Interferon; Antiviral
MeSH headings : Animals; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases / genetics; DNA (Cytosine-5-)-Methyltransferases / metabolism; DNA Methylation / genetics; DNA Methylation / physiology; Retroelements / genetics; Signal Transduction / genetics; Signal Transduction / physiology; Trans-Activators / genetics; Trans-Activators / metabolism; Zebrafish / embryology; Zebrafish / metabolism; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Angiopellosis as an Alternative Mechanism of Cell Extravasation
STEM CELLS, 35(1), 170–180.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Extravasation; Angiopellosis; Transmigration; Stem cell infusion; Diapedesis
MeSH headings : Animals; Blood Vessels / physiology; CD11 Antigens / metabolism; Cell Aggregation; Cell Membrane / metabolism; Cell Shape; Dogs; Extravasation of Diagnostic and Therapeutic Materials / pathology; Female; Humans; Injections; Intravital Microscopy; Male; Mesenchymal Stem Cells; Microspheres; Myocytes, Cardiac / cytology; Polymers / chemistry; Rats; Time Factors; Transendothelial and Transepithelial Migration; Zebrafish / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2012 journal article
B-cell lymphoma with plasmacytoid differentiation, atypical cytoplasmic inclusions, and secondary leukemia in a dog
Veterinary Clinical Pathology, 42(1), 40–46.
co-author countries:
United States of America 🇺🇸
author keywords: Clonality; immunophenotype; lymphocyte; MUM-1; Russell body
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Fatal Outcome; Inclusion Bodies / pathology; Leukemia / complications; Leukemia / drug therapy; Leukemia / veterinary; Lymphoma, B-Cell / complications; Lymphoma, B-Cell / drug therapy; Lymphoma, B-Cell / pathology; Lymphoma, B-Cell / veterinary; Male
Source: Crossref
Added: July 28, 2019
2012 journal article
Intrathoracic pulsion diverticulum in a horse
Canadian Veterinary Journal, 53, 408–411.
Source: NC State University Libraries
Added: July 28, 2019
2011 journal article
Amanitin Toxicosis in Two Cats with Acute Hepatic and Renal Failure
Veterinary Pathology, 49(6), 1032–1035.
co-author countries:
United States of America 🇺🇸
author keywords: amanitins; cats; gastrointestinal tract; kidney; liver; mushroom poisoning
MeSH headings : Alanine Transaminase / metabolism; Alpha-Amanitin / poisoning; Animals; Cat Diseases / etiology; Cat Diseases / pathology; Cats; Diagnosis, Differential; Fatal Outcome; Female; Gastrointestinal Tract / pathology; Humans; Kidney / pathology; Lethargy / veterinary; Liver / pathology; Liver Failure / etiology; Liver Failure / pathology; Liver Failure / veterinary; Male; Mushroom Poisoning / pathology; Mushroom Poisoning / veterinary; Necrosis / veterinary; Renal Insufficiency / etiology; Renal Insufficiency / pathology; Renal Insufficiency / veterinary
Source: Crossref
Added: July 28, 2019
2010 journal article
Salmon Poisoning Disease in Dogs: 29 Cases
Journal of Veterinary Internal Medicine, 24(3), 504–513.
co-author countries:
United States of America 🇺🇸
author keywords: Fish; Nanophyetus salmincola; Rickettsia; Trematode; Ultrasound
MeSH headings : Animal Feed; Animals; Anthelmintics / therapeutic use; Anti-Bacterial Agents / therapeutic use; California; Dog Diseases / drug therapy; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Female; Food Parasitology; Foodborne Diseases / veterinary; Male; Rickettsia Infections / drug therapy; Rickettsia Infections / epidemiology; Rickettsia Infections / veterinary; Salmon; Treatment Outcome; Trematoda / microbiology; Trematode Infections / drug therapy; Trematode Infections / parasitology; Trematode Infections / veterinary
Source: Crossref
Added: July 28, 2019
2008 journal article
Neuropathy Target Esterase Gene Mutations Cause Motor Neuron Disease
The American Journal of Human Genetics, 82(3), 780–785.
co-author countries:
United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Axons / physiology; Carboxylic Ester Hydrolases / genetics; Chromosome Mapping; Female; Genetic Linkage; Humans; Male; Molecular Sequence Data; Motor Neuron Disease / genetics; Mutation; Pedigree
Source: Crossref
Added: July 28, 2019
2005 journal article
Molecular characterization of isosporoid coccidia (Isospora and Atoxoplasma spp.) in passerine birds.
Journal of Parasitology, 91(3), 635–647.
MeSH headings : Animals; Base Sequence; Bird Diseases / parasitology; Coccidiosis / parasitology; Coccidiosis / veterinary; DNA, Protozoan / chemistry; DNA, Protozoan / isolation & purification; Eimeriidae / classification; Eimeriidae / genetics; Eimeriidae / ultrastructure; Genotype; HSP70 Heat-Shock Proteins / genetics; Isospora / classification; Isospora / genetics; Isospora / ultrastructure; Molecular Sequence Data; Passeriformes / parasitology; Phylogeny; Polymerase Chain Reaction / veterinary; RNA, Ribosomal / genetics; Sequence Alignment
Source: Crossref
Added: December 31, 2020
2004 journal article
Myofibrillogenesis Regulator 1 Gene Mutations Cause Paroxysmal Dystonic Choreoathetosis
Archives of Neurology, 61(7), 1025–1029.
co-author countries:
United States of America 🇺🇸
MeSH headings : Athetosis / genetics; Athetosis / physiopathology; Chorea / genetics; Chorea / physiopathology; Chromosomes, Human, Pair 2 / genetics; Dystonia / genetics; Dystonia / physiopathology; Female; Genes, Regulator / genetics; Genes, Regulator / physiology; Genetic Linkage / genetics; Haplotypes / genetics; Humans; Male; Muscle Development / genetics; Mutation; Pedigree; Physical Chromosome Mapping
Source: Crossref
Added: December 31, 2020
2003 journal article
NIPA1 Gene Mutations Cause Autosomal Dominant Hereditary Spastic Paraplegia (SPG6)
The American Journal of Human Genetics, 73(4), 967–971.
co-author countries:
Bulgaria 🇧🇬 United States of America 🇺🇸
MeSH headings : Base Sequence; Female; Genes, Dominant; Humans; Male; Membrane Proteins / genetics; Models, Molecular; Mutation; Pedigree; Protein Structure, Secondary; Reference Values; Spastic Paraplegia, Hereditary / genetics
Source: Crossref
Added: July 28, 2019
