Works (24)

Updated: August 22nd, 2023 21:16

2023 journal article

Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer?s disease mouse models

JOURNAL OF CELL SCIENCE, 136(6).

By: K. Sai n, A. Nakanishi n, K. Scofield n, D. Tokarz n, K. Linder n, T. Cohen*, J. Ninomiya-Tsuji n

co-author countries: United States of America 🇺🇸
author keywords: Alzheimer?s disease; Cell death; Inflammation; TAK1
MeSH headings : Animals; Mice; Alzheimer Disease / genetics; Calcium; Cytokines / metabolism; Neuroinflammatory Diseases; Signal Transduction / physiology
Sources: Web Of Science, ORCID
Added: May 30, 2023

2022 article

Inter-pathologist agreement on diagnosis, classification and grading of canine glioma

Krane, G. A., Shockley, K. R., Malarkey, D. E., Miller, A. D., Miller, C. R., Tokarz, D. A., … Mariani, C. L. (2022, July 30). VETERINARY AND COMPARATIVE ONCOLOGY, Vol. 7.

By: G. Krane n, K. Shockley*, D. Malarkey*, A. Miller*, C. Miller*, D. Tokarz n, H. Jensen*, K. Janardhan*, M. Breen n, C. Mariani n

co-author countries: United States of America 🇺🇸
author keywords: brain; cancer; dog; histopathology; immunohistochemistry
MeSH headings : Humans; Animals; Dogs; Oligodendroglioma / diagnosis; Oligodendroglioma / veterinary; Oligodendroglioma / pathology; Pathologists; Dog Diseases / diagnosis; Dog Diseases / pathology; Glioma / diagnosis; Glioma / veterinary; Glioma / pathology; Astrocytoma / veterinary; Brain Neoplasms / diagnosis; Brain Neoplasms / veterinary; Brain Neoplasms / pathology
Sources: Web Of Science, ORCID
Added: August 8, 2022

2021 article

Immunohistochemical evaluation of immune cell infiltration in canine gliomas

Krane, G. A., Carly A. O'Dea, Malarkey, D. E., Miller, A. D., Miller, C. R., Tokarz, D. A., … Mariani, C. L. (2021, July 1). VETERINARY PATHOLOGY, Vol. 7.

By: G. Krane n, . Carly A. O'Dea*, D. Malarkey*, A. Miller*, C. Miller*, D. Tokarz*, H. Jensen*, K. Janardhan* ...

co-author countries: United States of America 🇺🇸
author keywords: astrocytoma; brain; dogs; cancer; immunohistochemistry; immunology; lymphocytes; macrophages; oligodendroglioma
MeSH headings : Animals; Antigens, CD20; Dog Diseases; Dogs; Glioma / veterinary; Immunohistochemistry; Lymphocytes, Tumor-Infiltrating; T-Lymphocytes, Regulatory
Sources: Web Of Science, ORCID
Added: August 2, 2021

2021 journal article

Personalized-induced neural stem cell therapy: Generation, transplant, and safety in a large animal model

BIOENGINEERING & TRANSLATIONAL MEDICINE, 6(1).

By: H. Bomba*, K. Sheets*, A. Valdivia*, S. Khagi*, L. Ruterbories n, C. Mariani n, L. Borst n, D. Tokarz n, S. Hingtgen*

co-author countries: United States of America 🇺🇸
author keywords: glioblastoma; neural stem cells; stem cell delivery
Sources: Web Of Science, ORCID
Added: August 3, 2020

2021 journal article

Scavenger Receptor BI Attenuates IL-17A-Dependent Neutrophilic Inflammation in Asthma

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 64(6), 698–708.

By: S. Reece*, S. Varikuti*, B. Kilburg-Basnyat*, K. Dunigan-Russell*, M. Hodge*, B. Luo*, J. Madenspacher*, S. Thomas* ...

co-author countries: United States of America 🇺🇸
author keywords: asthma; IL-17A; SR-BI receptor; neutrophilia; adrenal insufficiency
MeSH headings : Adrenal Insufficiency / complications; Adrenal Insufficiency / immunology; Animals; Asthma / immunology; Asthma / metabolism; Asthma / parasitology; Asthma / pathology; CD36 Antigens / deficiency; CD36 Antigens / metabolism; Hypersensitivity / complications; Inflammation / pathology; Interleukin-17 / metabolism; Lung / parasitology; Lung / pathology; Male; Mice, Inbred C57BL; Neutrophils / immunology; Neutrophils / pathology; Ovalbumin / immunology; Pyroglyphidae / physiology; Th17 Cells / immunology
Source: Web Of Science
Added: June 28, 2021

2021 journal article

Sex Differences in Pulmonary Eicosanoids and Specialized Pro-Resolving Mediators in Response to Ozone Exposure

TOXICOLOGICAL SCIENCES, 183(1), 170–183.

By: M. Yaeger*, S. Reece*, B. Kilburg-Basnyat*, M. Hodge*, A. Pal*, K. Dunigan-Russell*, B. Luo*, D. You n ...

co-author countries: United States of America 🇺🇸
author keywords: air pollution; lipids; lung; inflammation; sex differences
MeSH headings : Animals; Eicosanoids; Female; Lung; Male; Mice; Mice, Inbred C57BL; Ozone / toxicity; Sex Characteristics
Source: Web Of Science
Added: September 27, 2021

2020 journal article

Matrix Metalloproteinase-12 Is Required for Granuloma Progression

FRONTIERS IN IMMUNOLOGY, 11.

By: A. Mohan*, N. Neequaye*, A. Malur*, E. Soliman*, M. McPeek*, N. Leffler*, D. Ogburn*, D. Tokarz n ...

co-author countries: Egypt 🇪🇬 United States of America 🇺🇸
author keywords: sarcoidosis; MMP12; PPAR gamma; MWCNT; granuloma; inflammation
MeSH headings : Animals; Granuloma / chemically induced; Granuloma / genetics; Granuloma / immunology; Granuloma / pathology; Macrophages, Alveolar / immunology; Macrophages, Alveolar / pathology; Matrix Metalloproteinase 12 / genetics; Matrix Metalloproteinase 12 / immunology; Mice; Mice, Knockout; Nanotubes, Carbon / adverse effects; Sarcoidosis, Pulmonary / chemically induced; Sarcoidosis, Pulmonary / genetics; Sarcoidosis, Pulmonary / immunology; Sarcoidosis, Pulmonary / pathology
Source: Web Of Science
Added: October 26, 2020

2019 journal article

Alveolar Macrophage ABCG1 Deficiency Promotes Pulmonary Granulomatous Inflammation

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 61(3), 332–340.

By: M. McPeek, A. Malur, D. Tokarz n, K. Lertpiriyapong*, K. Gowdy, G. Murray*, C. Wingard*, M. Fessler*, B. Barna, M. Thomassen

co-author countries: United States of America 🇺🇸
author keywords: pulmonary sarcoidosis; granuloma; alveolar macrophage; lipid transporters; carbon nanotubes
MeSH headings : ATP Binding Cassette Transporter 1 / genetics; ATP Binding Cassette Transporter, Subfamily G, Member 1 / deficiency; ATP-Binding Cassette Transporters / genetics; Animals; Granuloma / metabolism; Inflammation / metabolism; Lung / metabolism; Macrophages, Alveolar / metabolism; Mice, Knockout; Pneumonia / metabolism; Sarcoidosis, Pulmonary / metabolism
Source: Web Of Science
Added: September 23, 2019

2019 journal article

Cardiac Leiomyosarcoma in a Cat Presenting for Bilateral Renal Neoplasia

JOURNAL OF COMPARATIVE PATHOLOGY, 168, 19–24.

By: M. Schreeg n, B. Evans n, J. Allen n, M. Lewis n, E. Luckring n, M. Evola n, D. Richard, K. Piner* ...

co-author countries: United States of America 🇺🇸
author keywords: cardiac neoplasia; cat; immunohistochemistry; leiomyosarcoma
MeSH headings : Animals; Cat Diseases / pathology; Cats; Female; Heart Neoplasms / veterinary; Kidney Neoplasms / veterinary; Leiomyosarcoma / veterinary
Source: Web Of Science
Added: June 4, 2019

2018 journal article

A de novo mutation in the EXT2 gene associated with osteochondromatosis in a litter of American Staffordshire Terriers

Journal of Veterinary Internal Medicine, 32(3), 986–992.

By: S. Friedenberg*, D. Vansteenkiste*, O. Yost n, A. Treeful*, K. Meurs n, D. Tokarz n, N. Olby n

co-author countries: United States of America 🇺🇸
author keywords: bone; cartilage; genetics; multiple cartilaginous exostoses; mutation; osteochondroma
MeSH headings : Animals; Cartilage / pathology; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genetic Variation / genetics; Male; Mosaicism / veterinary; N-Acetylglucosaminyltransferases / genetics; Osteochondromatosis / genetics; Osteochondromatosis / pathology; Osteochondromatosis / veterinary; Polymorphism, Single Nucleotide / genetics; Whole Genome Sequencing / veterinary
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2018 journal article

C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event

Cell Death & Disease, 9(11).

By: Z. Messenger*, J. Hall*, D. Jima*, J. House*, H. Tam, D. Tokarz n, R. Smart*

co-author countries: United States of America 🇺🇸

Contributors: Z. Messenger*, J. Hall*, D. Jima*, J. House*, H. Tam, D. Tokarz n, R. Smart*

MeSH headings : 9,10-Dimethyl-1,2-benzanthracene / administration & dosage; Animals; Apoptosis / drug effects; Apoptosis / genetics; CCAAT-Enhancer-Binding Protein-beta / deficiency; CCAAT-Enhancer-Binding Protein-beta / genetics; Cell Differentiation; Cell Transformation, Neoplastic / genetics; Cell Transformation, Neoplastic / metabolism; Cell Transformation, Neoplastic / pathology; Gene Expression Regulation, Neoplastic; Genes, Lethal; Keratinocytes / drug effects; Keratinocytes / metabolism; Keratinocytes / pathology; Mice; Mice, Knockout; Receptors, Death Domain / genetics; Receptors, Death Domain / metabolism; Signal Transduction; Skin / drug effects; Skin / metabolism; Skin / pathology; Skin Neoplasms / chemically induced; Skin Neoplasms / genetics; Skin Neoplasms / metabolism; Skin Neoplasms / pathology; Tetradecanoylphorbol Acetate / administration & dosage; Tetradecanoylphorbol Acetate / analogs & derivatives; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / metabolism; ras Proteins / genetics; ras Proteins / metabolism
Sources: Web Of Science, Crossref, ORCID
Added: October 29, 2018

2018 journal article

PPAR-gamma pathways attenuate pulmonary granuloma formation in a carbon nanotube induced murine model of sarcoidosis

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 503(2), 684–690.

By: M. McPeek*, A. Malur*, D. Tokarz n, G. Murray*, B. Barna* & M. Thomassen*

co-author countries: United States of America 🇺🇸
author keywords: Sarcoidosis; Granuloma; Carbon nanotube; Inflammation; Lipid transporters; Alveolar macrophage
MeSH headings : Animals; Disease Models, Animal; Dyslipidemias / etiology; Dyslipidemias / genetics; Dyslipidemias / metabolism; Dyslipidemias / pathology; Gene Expression Regulation; Granuloma / etiology; Granuloma / genetics; Granuloma / metabolism; Granuloma / pathology; Lung / metabolism; Lung / pathology; Lung Diseases / etiology; Lung Diseases / genetics; Lung Diseases / metabolism; Lung Diseases / pathology; Macrophages, Alveolar / metabolism; Macrophages, Alveolar / pathology; Mice, Inbred C57BL; Nanotubes, Carbon / adverse effects; PPAR gamma / agonists; PPAR gamma / metabolism; Sarcoidosis / etiology; Sarcoidosis / genetics; Sarcoidosis / metabolism; Sarcoidosis / pathology; Signal Transduction
Source: Web Of Science
Added: October 19, 2018

2018 journal article

Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes

NANOTOXICOLOGY, 12(9), 975–991.

By: K. Duke n, E. Thompson n, M. Ihrie n, A. Taylor-Just n, E. Ash n, K. Shipkowski n, J. Hall n, D. Tokarz n ...

co-author countries: United States of America 🇺🇸
author keywords: Caron nanotubes; immunotoxicology; cancer; granuloma; p53
MeSH headings : Animals; Dose-Response Relationship, Drug; Granuloma, Respiratory Tract / chemically induced; Granuloma, Respiratory Tract / genetics; Granuloma, Respiratory Tract / immunology; Inhalation Exposure; Lung / drug effects; Lung / immunology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Surface Properties; Tertiary Lymphoid Structures / chemically induced; Tertiary Lymphoid Structures / genetics; Tertiary Lymphoid Structures / immunology; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / physiology
Source: Web Of Science
Added: March 4, 2019

2017 journal article

Disruption of Trim9 function abrogates macrophage motility in vivo

Journal of Leukocyte Biology, 102(6), 1371–1380.

By: D. Tokarz n, A. Heffelfinger n, D. Jima n, J. Gerlach n, R. Shah n, I. Rodriguez-Nunez n, A. Kortum n, A. Fletcher n ...

co-author countries: United States of America 🇺🇸
author keywords: chemotaxis; zebrafish; leukocyte; ubiquitin
MeSH headings : Animals; Cell Movement / genetics; Cell Shape; Chemotaxis; Humans; Macrophages / cytology; Macrophages / metabolism; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Tripartite Motif Proteins / genetics; Tripartite Motif Proteins / metabolism; U937 Cells; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling

Development, 144(16), 2925–2939.

By: Y. Chernyavskaya*, R. Mudbhary*, C. Zhang n, D. Tokarz*, V. Jacob*, S. Gopinath*, X. Sun*, S. Wang* ...

co-author countries: United Arab Emirates 🇦🇪 United States of America 🇺🇸
author keywords: Transposon; DNA methylation; Uhrf1; Interferon; Antiviral
MeSH headings : Animals; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases / genetics; DNA (Cytosine-5-)-Methyltransferases / metabolism; DNA Methylation / genetics; DNA Methylation / physiology; Retroelements / genetics; Signal Transduction / genetics; Signal Transduction / physiology; Trans-Activators / genetics; Trans-Activators / metabolism; Zebrafish / embryology; Zebrafish / metabolism; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Angiopellosis as an Alternative Mechanism of Cell Extravasation

STEM CELLS, 35(1), 170–180.

By: T. Allen n, D. Gracieux n, M. Talib n, D. Tokarz n, M. Hensley n, J. Cores n, A. Vandergriff n, J. Tang n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Extravasation; Angiopellosis; Transmigration; Stem cell infusion; Diapedesis
MeSH headings : Animals; Blood Vessels / physiology; CD11 Antigens / metabolism; Cell Aggregation; Cell Membrane / metabolism; Cell Shape; Dogs; Extravasation of Diagnostic and Therapeutic Materials / pathology; Female; Humans; Injections; Intravital Microscopy; Male; Mesenchymal Stem Cells; Microspheres; Myocytes, Cardiac / cytology; Polymers / chemistry; Rats; Time Factors; Transendothelial and Transepithelial Migration; Zebrafish / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

B-cell lymphoma with plasmacytoid differentiation, atypical cytoplasmic inclusions, and secondary leukemia in a dog

Veterinary Clinical Pathology, 42(1), 40–46.

By: A. Kol*, M. Christopher*, K. Skorupski*, D. Tokarz* & W. Vernau*

co-author countries: United States of America 🇺🇸
author keywords: Clonality; immunophenotype; lymphocyte; MUM-1; Russell body
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Fatal Outcome; Inclusion Bodies / pathology; Leukemia / complications; Leukemia / drug therapy; Leukemia / veterinary; Lymphoma, B-Cell / complications; Lymphoma, B-Cell / drug therapy; Lymphoma, B-Cell / pathology; Lymphoma, B-Cell / veterinary; Male
Source: Crossref
Added: July 28, 2019

2012 journal article

Intrathoracic pulsion diverticulum in a horse

Canadian Veterinary Journal, 53, 408–411.

By: S. Yamout, D. Tokarz, K. Magdesian & S. le Jeune

Source: NC State University Libraries
Added: July 28, 2019

2011 journal article

Amanitin Toxicosis in Two Cats with Acute Hepatic and Renal Failure

Veterinary Pathology, 49(6), 1032–1035.

By: D. Tokarz*, R. Poppenga, J. Kaae, M. Filigenzi, L. Lowenstine* & P. Pesavento*

co-author countries: United States of America 🇺🇸
author keywords: amanitins; cats; gastrointestinal tract; kidney; liver; mushroom poisoning
MeSH headings : Alanine Transaminase / metabolism; Alpha-Amanitin / poisoning; Animals; Cat Diseases / etiology; Cat Diseases / pathology; Cats; Diagnosis, Differential; Fatal Outcome; Female; Gastrointestinal Tract / pathology; Humans; Kidney / pathology; Lethargy / veterinary; Liver / pathology; Liver Failure / etiology; Liver Failure / pathology; Liver Failure / veterinary; Male; Mushroom Poisoning / pathology; Mushroom Poisoning / veterinary; Necrosis / veterinary; Renal Insufficiency / etiology; Renal Insufficiency / pathology; Renal Insufficiency / veterinary
Source: Crossref
Added: July 28, 2019

2010 journal article

Salmon Poisoning Disease in Dogs: 29 Cases

Journal of Veterinary Internal Medicine, 24(3), 504–513.

By: J. Sykes*, S. Marks*, S. Mapes*, R. Schultz*, R. Pollard*, D. Tokarz*, P. Pesavento*, L. Lindsay*, J. Foley*

co-author countries: United States of America 🇺🇸
author keywords: Fish; Nanophyetus salmincola; Rickettsia; Trematode; Ultrasound
MeSH headings : Animal Feed; Animals; Anthelmintics / therapeutic use; Anti-Bacterial Agents / therapeutic use; California; Dog Diseases / drug therapy; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Female; Food Parasitology; Foodborne Diseases / veterinary; Male; Rickettsia Infections / drug therapy; Rickettsia Infections / epidemiology; Rickettsia Infections / veterinary; Salmon; Treatment Outcome; Trematoda / microbiology; Trematode Infections / drug therapy; Trematode Infections / parasitology; Trematode Infections / veterinary
Source: Crossref
Added: July 28, 2019

2008 journal article

Neuropathy Target Esterase Gene Mutations Cause Motor Neuron Disease

The American Journal of Human Genetics, 82(3), 780–785.

By: S. Rainier*, M. Bui*, E. Mark*, D. Thomas*, D. Tokarz*, L. Ming*, C. Delaney*, R. Richardson* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Axons / physiology; Carboxylic Ester Hydrolases / genetics; Chromosome Mapping; Female; Genetic Linkage; Humans; Male; Molecular Sequence Data; Motor Neuron Disease / genetics; Mutation; Pedigree
Source: Crossref
Added: July 28, 2019

2005 journal article

Molecular characterization of isosporoid coccidia (Isospora and Atoxoplasma spp.) in passerine birds.

Journal of Parasitology, 91(3), 635–647.

By: M. Schrenzel, G. Maalouf, P. Gaffney, D. Tokarz*, L. Keener, D. McClure, S. Griffey, D. McAloose, B. Rideout

MeSH headings : Animals; Base Sequence; Bird Diseases / parasitology; Coccidiosis / parasitology; Coccidiosis / veterinary; DNA, Protozoan / chemistry; DNA, Protozoan / isolation & purification; Eimeriidae / classification; Eimeriidae / genetics; Eimeriidae / ultrastructure; Genotype; HSP70 Heat-Shock Proteins / genetics; Isospora / classification; Isospora / genetics; Isospora / ultrastructure; Molecular Sequence Data; Passeriformes / parasitology; Phylogeny; Polymerase Chain Reaction / veterinary; RNA, Ribosomal / genetics; Sequence Alignment
Source: Crossref
Added: December 31, 2020

2004 journal article

Myofibrillogenesis Regulator 1 Gene Mutations Cause Paroxysmal Dystonic Choreoathetosis

Archives of Neurology, 61(7), 1025–1029.

By: S. Rainier*, D. Thomas*, D. Tokarz*, L. Ming*, M. Bui*, E. Plein*, X. Zhao*, R. Lemons* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Athetosis / genetics; Athetosis / physiopathology; Chorea / genetics; Chorea / physiopathology; Chromosomes, Human, Pair 2 / genetics; Dystonia / genetics; Dystonia / physiopathology; Female; Genes, Regulator / genetics; Genes, Regulator / physiology; Genetic Linkage / genetics; Haplotypes / genetics; Humans; Male; Muscle Development / genetics; Mutation; Pedigree; Physical Chromosome Mapping
Source: Crossref
Added: December 31, 2020

2003 journal article

NIPA1 Gene Mutations Cause Autosomal Dominant Hereditary Spastic Paraplegia (SPG6)

The American Journal of Human Genetics, 73(4), 967–971.

By: S. Rainier*, J. Chai*, D. Tokarz*, R. Nicholls* & J. Fink*

co-author countries: Bulgaria 🇧🇬 United States of America 🇺🇸
MeSH headings : Base Sequence; Female; Genes, Dominant; Humans; Male; Membrane Proteins / genetics; Models, Molecular; Mutation; Pedigree; Protein Structure, Secondary; Reference Values; Spastic Paraplegia, Hereditary / genetics
Source: Crossref
Added: July 28, 2019

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