Works (20)

Updated: July 5th, 2023 16:03

2022 article

Inter-pathologist agreement on diagnosis, classification and grading of canine glioma

Krane, G. A., Shockley, K. R., Malarkey, D. E., Miller, A. D., Miller, C. R., Tokarz, D. A., … Mariani, C. L. (2022, July 30). VETERINARY AND COMPARATIVE ONCOLOGY, Vol. 7.

author keywords: brain; cancer; dog; histopathology; immunohistochemistry
MeSH headings : Humans; Animals; Dogs; Oligodendroglioma / diagnosis; Oligodendroglioma / veterinary; Oligodendroglioma / pathology; Pathologists; Dog Diseases / diagnosis; Dog Diseases / pathology; Glioma / diagnosis; Glioma / veterinary; Glioma / pathology; Astrocytoma / veterinary; Brain Neoplasms / diagnosis; Brain Neoplasms / veterinary; Brain Neoplasms / pathology
Sources: Web Of Science, ORCID
Added: August 8, 2022

2021 journal article

A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat


By: K. Meurs n, B. Williams n, D. DeProspero n, S. Friedenberg*, D. Malarkey*, J. Ezzell*, B. Keene n, D. Adin n, T. DeFrancesco n, S. Tou n

author keywords: Hypertrophic cardiomyopathy; ALMS1; Feline; Mitogenic; Sphynx
MeSH headings : Animals; Cardiomyopathy, Hypertrophic / genetics; Cats / genetics; Cell Cycle Proteins / genetics; Exons; Mice; Mutation / genetics
Sources: Web Of Science, ORCID
Added: April 12, 2021

2021 article

Immunohistochemical evaluation of immune cell infiltration in canine gliomas

Krane, G. A., Carly A. O'Dea, Malarkey, D. E., Miller, A. D., Miller, C. R., Tokarz, D. A., … Mariani, C. L. (2021, July 1). VETERINARY PATHOLOGY, Vol. 7.

By: G. Krane n, . Carly A. O'Dea*, D. Malarkey*, A. Miller*, C. Miller*, D. Tokarz*, H. Jensen*, K. Janardhan* ...

author keywords: astrocytoma; brain; dogs; cancer; immunohistochemistry; immunology; lymphocytes; macrophages; oligodendroglioma
MeSH headings : Animals; Antigens, CD20; Dog Diseases; Dogs; Glioma / veterinary; Immunohistochemistry; Lymphocytes, Tumor-Infiltrating; T-Lymphocytes, Regulatory
Sources: Web Of Science, ORCID
Added: August 2, 2021

2009 journal article

Expression of epidermal growth factor receptor and vascular endothelial growth factor in malignant canine epithelial nasal tumours


By: K. Shiomitsu n, C. Johnson n, D. Malarkey*, A. Pruitt n & D. Thrall n

author keywords: canine; EGFR; nasal tumour; radiosensitivity; VEGF
MeSH headings : Animals; Dog Diseases / metabolism; Dog Diseases / pathology; Dog Diseases / radiotherapy; Dogs; ErbB Receptors / metabolism; Gene Expression Regulation, Neoplastic; Immunohistochemistry / veterinary; Neoplasms, Glandular and Epithelial / metabolism; Neoplasms, Glandular and Epithelial / pathology; Neoplasms, Glandular and Epithelial / radiotherapy; Neoplasms, Glandular and Epithelial / veterinary; Nose Neoplasms / radiotherapy; Nose Neoplasms / veterinary; Treatment Outcome; Vascular Endothelial Growth Factor A / metabolism
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Epibulbar melanoma in a foal

Veterinary Ophthalmology, 11, 44–50.

By: R. McMullen, A. Clode*, A. Pandiri n, D. Malarkey*, T. Michau* & B. Gilger*

author keywords: congenital; epibulbar; equine; melanoma; neoplasia
MeSH headings : Animals; Animals, Newborn; Choroid Neoplasms / pathology; Choroid Neoplasms / surgery; Choroid Neoplasms / veterinary; Eye Enucleation / methods; Eye Enucleation / veterinary; Eye Neoplasms / pathology; Eye Neoplasms / surgery; Eye Neoplasms / veterinary; Horse Diseases / pathology; Horse Diseases / surgery; Horses; Limbus Corneae; Macrophages / pathology; Male; Melanoma / pathology; Melanoma / surgery; Melanoma / veterinary; Pigment Epithelium of Eye / pathology; Treatment Outcome
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2004 article

Expression of cyclooxygenase-2 in canine epithelial nasal tumors


By: M. Kleiter n, D. Malarkey*, D. Ruslander n & D. Thrall n

author keywords: canine; cyclooxygenase-2; nasal tumors; radiation therapy
MeSH headings : Adenocarcinoma / enzymology; Adenocarcinoma / veterinary; Animals; Carcinoma, Squamous Cell / enzymology; Carcinoma, Squamous Cell / veterinary; Case-Control Studies; Combined Modality Therapy; Cyclooxygenase 2; Dog Diseases / drug therapy; Dog Diseases / enzymology; Dog Diseases / radiotherapy; Dogs; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Isoenzymes / metabolism; Nose Neoplasms / enzymology; Nose Neoplasms / veterinary; Prostaglandin-Endoperoxide Synthases / metabolism; Records / veterinary; Retrospective Studies
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Identification of spontaneous feline idiopathic pulmonary fibrosis - Morphology and ultrastructural evidence for a type II pneumocyte defect

CHEST, 125(6), 2278–2288.

By: K. Williams*, D. Malarkey n, L. Cohn*, D. Patrick*, J. Dye* & G. Toews*

author keywords: animal model; cats; fibrosis; idiopathic pulmonary fibrosis; lung; type II pneumocytes
MeSH headings : Animals; Apoptosis; Cats; Culture Techniques; Disease Models, Animal; Female; Immunohistochemistry; Male; Microscopy, Electron; Probability; Pulmonary Alveoli / cytology; Pulmonary Alveoli / ultrastructure; Pulmonary Fibrosis / pathology; Reference Values; Sensitivity and Specificity
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Radiographic features of aortic bulb/valve mineralization in 20 dogs


By: J. Douglass n, C. Berry n, D. Thrall n, D. Malarkey n & K. Spaulding n

author keywords: canine; aortic bulb mineralization; radiography
MeSH headings : Animals; Aortic Valve / diagnostic imaging; Aortic Valve / pathology; Calcification, Physiologic; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Female; Male; Radiography
Source: Web Of Science
Added: August 6, 2018

2002 article

Heterobilharzia americana infection in a dog

Flowers, JR, Hammerberg, B., Wood, S. L., Malarkey, D. E., Dam, G. J., Levy, M. G., & McLawhorn, L. D. (2002, January 15). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 220, pp. 193–196.

By: . Flowers, B. Hammerberg*, S. Wood, D. Malarkey*, G. Dam, M. Levy*, L. McLawhorn

MeSH headings : Animals; Anthelmintics / therapeutic use; Antigens, Helminth / blood; Antigens, Helminth / immunology; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Feces / parasitology; Male; Parasite Egg Count / veterinary; Praziquantel / therapeutic use; Schistosomatidae / isolation & purification; Trematode Infections / diagnosis; Trematode Infections / drug therapy; Trematode Infections / parasitology; Trematode Infections / veterinary
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Lack of teratogenicity of microcystin-LR in the mouse and toad


By: N. Chernoff*, E. Hunter*, L. Hall*, M. Rosen*, C. Brownie n, D. Malarkey n, M. Marr*, J. Herkovits*

author keywords: microcystin; developmental toxicology; mouse; frog; embryo
MeSH headings : Animals; Bufo arenarum / abnormalities; Cyanobacteria / pathogenicity; Embryo, Mammalian / abnormalities; Embryo, Mammalian / drug effects; Embryo, Nonmammalian / abnormalities; Embryo, Nonmammalian / drug effects; Enzyme Inhibitors / administration & dosage; Enzyme Inhibitors / toxicity; Female; In Vitro Techniques; Lethal Dose 50; Marine Toxins; Maternal Exposure / adverse effects; Mice; Microcystins; Peptides, Cyclic / administration & dosage; Peptides, Cyclic / toxicity; Survival Rate; Toxicity Tests, Acute
Source: Web Of Science
Added: August 6, 2018

2002 article

The hepatic endothelial carcinogen riddelliine induces endothelial apoptosis, mitosis, S phase, and p53 and hepatocytic vascular endothelial growth factor expression after short-term exposure

Nyska, A., Moomaw, C. R., Foley, J. F., Maronpot, R. R., Malarkey, D. E., Cummings, C. A., … Chan, P. C. (2002, November 1). TOXICOLOGY AND APPLIED PHARMACOLOGY, Vol. 184, pp. 153–164.

By: A. Nyska*, C. Moomaw, J. Foley, R. Maronpot, D. Malarkey, C. Cummings, S. Peddada, C. Moyer ...

author keywords: pyrrolizidine alkaloid; endothelium; hemangiosarcoma; cytotoxicity; vascular endothelial growth factor; VEGFR2; BrdU; factor VIII-related antigen; von Willebrand factor; p53
MeSH headings : Administration, Oral; Animals; Apoptosis / drug effects; Bromodeoxyuridine / metabolism; Carcinogens / administration & dosage; Carcinogens / toxicity; Dose-Response Relationship, Drug; Endothelial Growth Factors / blood; Hepatocytes / drug effects; Hepatocytes / metabolism; Hepatocytes / pathology; Immunoenzyme Techniques; Intercellular Signaling Peptides and Proteins / blood; Kupffer Cells / drug effects; Kupffer Cells / metabolism; Kupffer Cells / pathology; Liver / drug effects; Liver / metabolism; Liver / pathology; Lymphokines / blood; Male; Mitosis; Pyrrolizidine Alkaloids / administration & dosage; Pyrrolizidine Alkaloids / toxicity; Rats; Rats, Inbred F344; S Phase / drug effects; Tumor Suppressor Protein p53 / metabolism; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 / metabolism; Vascular Endothelial Growth Factors; von Willebrand Factor / metabolism
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Natural history of hypertrophic cardiomyopathy and aortic thromboembolism in a family of domestic shorthair cats


By: C. Baty n, D. Malarkey n, C. Atkins n, T. DeFrancesco n, J. Sidley n & B. Keene n

author keywords: cardiac myocyte disarray; end stage; spontaneous echo contrast; systolic function; ventricular remodeling
Sources: Web Of Science, ORCID
Added: August 6, 2018

2000 journal article

Histologic and immunohistochemical characterization of lens capsular plaques in dogs with cataracts


By: C. Colitz n, D. Malarkey*, M. Dykstra*, M. McGahan & M. Davidson*

MeSH headings : Actins / analysis; Animals; Cataract / pathology; Cataract / veterinary; Cataract Extraction / veterinary; Dog Diseases / pathology; Dogs; Fibronectins / analysis; Histocytochemistry; Humans; Immunohistochemistry / methods; Lens, Crystalline / pathology; Lens, Crystalline / ultrastructure; Tenascin / analysis; Transforming Growth Factor beta / analysis
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Persistent hyperplastic tunica vasculosa lentis and persistent hyperplastic primary vitreous in transgenic line TgN3261Rpw


By: C. Colitz n, D. Malarkey n, R. Woychik* & J. Wilkinson*

author keywords: embryology; eye; mice; persistent hyperplastic primary vitreous; persistent hyperplastic tunica vasculosa lentis
MeSH headings : Animals; Blotting, Southern / veterinary; Dog Diseases / pathology; Dogs; Eye Abnormalities / pathology; Eye Abnormalities / veterinary; Hyperplasia / pathology; Hyperplasia / veterinary; Lens, Crystalline / abnormalities; Lens, Crystalline / embryology; Mice; Mice, Mutant Strains / embryology; Mice, Transgenic / embryology; Mutagenesis, Insertional; Vitreous Body / abnormalities; Vitreous Body / embryology
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice

CARCINOGENESIS, 20(8), 1583–1590.

By: J. Christensen*, E. Romach*, L. Healy*, A. Gonzales*, S. Anderson*, D. Malarkey n, J. Corton*, T. Fox*, R. Cattley*, T. Goldsworthy*

MeSH headings : Adenoma / chemically induced; Adenoma / metabolism; Adenoma / pathology; Animals; Apoptosis; Carcinogens; Carcinoma / chemically induced; Carcinoma / metabolism; Carcinoma / pathology; Carrier Proteins / metabolism; Chlordan; DNA-Binding Proteins; Liver Neoplasms, Experimental / chemically induced; Liver Neoplasms, Experimental / metabolism; Liver Neoplasms, Experimental / pathology; Male; Mice; Neoplasm Proteins / metabolism; Phenobarbital; Phenotype; Polychlorinated Dibenzodioxins; Proto-Oncogene Proteins / metabolism; Proto-Oncogene Proteins c-bcl-2 / metabolism; Pyrimidines; Transcription Factors; bcl-2-Associated X Protein; bcl-X Protein
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Association of v-Ha-ras transgene expression with development of erythroleukemia in Tg.AC transgenic mice


By: C. Trempus*, S. Ward*, G. Farris*, D. Malarkey*, R. Faircloth*, R. Cannon*, J. Mahler*

MeSH headings : Animals; Blood Cell Count; Blood Cells / metabolism; Bone Marrow / metabolism; DNA-Binding Proteins / metabolism; Erythroid-Specific DNA-Binding Factors; GATA1 Transcription Factor; Genes, ras / genetics; Globins / metabolism; Leukemia, Erythroblastic, Acute / genetics; Leukemia, Erythroblastic, Acute / metabolism; Leukemia, Erythroblastic, Acute / pathology; Liver / metabolism; Liver / pathology; Mice; Mice, Transgenic; Organ Size; Polymerase Chain Reaction; Spleen / metabolism; Spleen / pathology; Transcription Factors / metabolism; Transcription, Genetic; ras Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Effect of the viable-yellow (A(vy)) agouti allele on skin tumorigenesis and humoral hypercalcemia in v-Ha-ras transgenic TG.AC mice

CARCINOGENESIS, 19(10), 1837–1845.

By: L. Hansen*, D. Malarkey*, J. Wilkinson*, M. Rosenberg*, R. Woychik* & R. Tennant*

MeSH headings : Agouti Signaling Protein; Alleles; Animals; Base Sequence; Body Weight; DNA Primers; Genes, ras; Hypercalcemia / complications; Hypercalcemia / genetics; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma / chemically induced; Papilloma / complications; Papilloma / genetics; Proteins / genetics; Skin Neoplasms / chemically induced; Skin Neoplasms / complications; Skin Neoplasms / genetics; Tetradecanoylphorbol Acetate / toxicity
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Impact of Helicobacter hepaticus infection in B6C3F(1) mice from twelve national toxicology program two-year carcinogenesis studies


By: . Hailey*, J. Haseman*, . Bucher*, A. Radovsky*, D. Malarkey n, R. Miller n, A. Nyska*, R. Maronpot*

author keywords: liver neoplasia; mice; hemangiosarcoma; cell proliferation; H-ras; hepatitis
MeSH headings : Animals; Carcinogenicity Tests; Cell Cycle / physiology; Female; Genes, ras; Helicobacter; Helicobacter Infections / complications; Hepatitis / microbiology; Liver Neoplasms, Experimental / genetics; Liver Neoplasms, Experimental / microbiology; Male; Mice; Mice, Inbred Strains; Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rats; Rats, Inbred F344
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Spontaneous and chemically induced proliferative lesions in Tg.AC transgenic and p53-heterozygous mice


By: J. Mahler*, N. Flagler*, D. Malarkey n, P. Mann*, J. Haseman* & W. Eastin*

author keywords: mice; genetically altered; hazard identification; neoplasms; carcinogenicity
MeSH headings : Animals; Carcinogenicity Tests / methods; Carcinogens / toxicity; Genes, p53 / genetics; Heterozygote; Mice; Mice, Transgenic / genetics; Mice, Transgenic / physiology; Neoplasms, Experimental / chemically induced; Neoplasms, Experimental / genetics; Neoplasms, Experimental / pathology
Source: Web Of Science
Added: August 6, 2018

1997 journal article

A PCR-RFLP method for the detection of Helicobacter hepaticus in frozen or fixed liver from B6C3F(1) mice


By: D. Malarkey*, T. Ton*, . Hailey* & T. Devereux*

author keywords: mouse liver carcinogenesis; diagnostic assay; archival tissues; sensitivity; specificity; bioassay; National Toxicology Program (NTP)
MeSH headings : Animals; DNA, Bacterial / analysis; Female; Formaldehyde; Frozen Sections; Helicobacter / genetics; Helicobacter Infections / pathology; Liver / microbiology; Liver / pathology; Male; Mice; Mice, Inbred Strains; Paraffin Embedding; Polymerase Chain Reaction / methods; Polymorphism, Restriction Fragment Length; Tissue Fixation
Source: Web Of Science
Added: August 6, 2018