Works (45)

Updated: October 30th, 2024 05:02

2024 article

136 Evaluation of internal parasite burden in grazing beef cattle in North Carolina over a production lifecycle

Williams, K. G., Pickworth, C. L., Weaver, A. R., & Poole, D. H. (2024, March 2). JOURNAL OF ANIMAL SCIENCE, Vol. 102, pp. 67–68.

By: K. Williams*, C. Pickworth n, A. Weaver n & D. Poole n

author keywords: beef; lifecycle; parasites
Sources: Web Of Science, NC State University Libraries
Added: March 25, 2024

2024 journal article

Examining the long-term impacts of ergot alkaloids on fetal heifer development and subsequent growth and reproductive performance

JOURNAL OF ANIMAL SCIENCE, 102.

By: M. Haimon n, R. Poole n, M. Newsome n, A. Brown n, H. Dudley n & D. Poole n

author keywords: beef heifers; ergot alkaloids; fetal programming
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 3, 2024

2024 journal article

Exploring the impacts of fescue toxicosis on the pulmonary arterial pressure of angus cows

JOURNAL OF ANIMAL SCIENCE, 102.

By: E. Rajo-Gomez n, M. Giurgis n, C. Pickworth n, A. Weaver n, D. Foster n, P. Khanal*, D. Poole n

author keywords: fescue toxicosis; pregnant cows; pulmonary arterial pressure
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 8, 2024

2024 article

Exposure to ergot alkaloids and heat stress alter pulmonary arterial pressure and nutritional intake in beef heifers

Rajo, E. B., Weaver, A. R., Pickworth, C. L., Foster, D., & Poole, D. H. (2024, September 13). JOURNAL OF ANIMAL SCIENCE, Vol. 102, pp. 271–272.

By: E. Rajo n, A. Weaver n, C. Pickworth n, D. Foster n & D. Poole n

author keywords: ergot alkaloids; pulmonary arterial pressure; water intake
Sources: Web Of Science, NC State University Libraries
Added: September 30, 2024

2024 article

Impact of progesterone signaling on tumor necrosis factor-alpha synthesis by luteal macrophages

Giurgis, M., McCann-Deshazer, M., Gadsby, J. E., & Poole, D. H. (2024, March 2). JOURNAL OF ANIMAL SCIENCE, Vol. 102, pp. 55–56.

By: M. Giurgis n, M. McCann-Deshazer n, J. Gadsby n & D. Poole n

author keywords: Luteolysis; Macrophage; Progesterone
TL;DR: Collectively, TRIL treatment effectively reduced P4 synthesis in LC cultures, and the greater concentration of TRIL is needed for P4 suppression in longer term culture systems. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 25, 2024

2023 article

Awardee Talk: Foraging for Collaboration: Beef-Forage System Strengths Unite Research and Extension Efforts in the Asas Southern Section

Mullenix, K., Gadberry, S., Rhinehart, J. D., Dillard, S. L., Tucker, J. J. J., Stewart, R. L., … Soffa, D. R. (2023, November 6). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 152–153.

By: K. Mullenix*, S. Gadberry, J. Rhinehart*, S. Dillard*, J. Tucker, R. Stewart, J. Vendramini, D. Poole n ...

Sources: Web Of Science, NC State University Libraries
Added: December 18, 2023

2023 article

Exposure to Endophyte-Infected Tall Fescue Negatively Impacts Pulmonary Arterial Pressure in Beef Cattle

Rajo, E. B., Williams, K., Pickworth, C. L., Foster, D., & Poole, D. H. (2023, May). JOURNAL OF ANIMAL SCIENCE, Vol. 101.

By: E. Rajo n, K. Williams n, C. Pickworth n, D. Foster n & D. Poole n

author keywords: cow productivity; fescue; pulmonary arterial pressure
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024

2023 article

Impact of Fescue Variety on Fecal Egg Counts in Mature Beef Cattle

Williams, K., Rajo, E. B., Weaver, A. R., Poole, D. H., & Pickworth, C. L. (2023, May). JOURNAL OF ANIMAL SCIENCE, Vol. 101.

By: K. Williams n, E. Rajo n, A. Weaver n, D. Poole n & C. Pickworth n

author keywords: fescue; parasite; cattle
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024

2020 journal article

Beef cattle that respond differently to fescue toxicosis have distinct gastrointestinal tract microbiota

PLOS ONE, 15(7).

MeSH headings : Animals; Ascomycota / isolation & purification; Ascomycota / metabolism; Cattle; Discriminant Analysis; Epichloe / metabolism; Ergot Alkaloids / analysis; Ergot Alkaloids / toxicity; Feces / microbiology; Gastrointestinal Microbiome / drug effects; Lolium / microbiology; Neocallimastigales / isolation & purification; Neocallimastigales / metabolism; Symbiosis; Toxins, Biological / analysis; Toxins, Biological / toxicity
TL;DR: This study reveals significantly (P<0.05) different bacterial and fungal microbiota between HT and LT cattle, and indicates that fungal phylotypes may be important for an animal’s response to fescue toxicosis, and found that fungan phylotypes affiliating to the Neocallimastigaceae were consistently more abundant in the HT cattle. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2020

2020 article

Changes in Cytokine Profiles in Response to Ergovaline Exposure in Slick vs. Normal Hair Coat in Beef Heifers.

Brown, A. R., Haimon, M. K. L., Poole, R., Poore, M. H., & Poole, D. H. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 40–40.

By: A. Brown n, M. Haimon n, R. Poole*, M. Poore n & D. Poole n

TL;DR: In contrast to previous data, exposure to ergovaline via endophyte-infected fescue, did not induce an innate immune response, and cytokine concentrations were elevated in heifers with the slick hair genotype. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 1, 2021

2020 article

Changes in growth performance, feeding behaviors, and posture behaviors of growing pigs subjected to low-intensity heat stress

Anderson, L. E., Holt, J. P., Heugten, E., & Poole, D. H. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 3–3.

By: L. Anderson n, J. Holt n, E. Heugten n & D. Poole n

author keywords: heat stress behavior
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021

2020 article

Changes in serum cortisol concentrations and cytokine profiles of growing pigs subjected to low-intensity heat stress

Anderson, L. E., Holt, J. P., Heugten, E., & Poole, D. H. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 266–266.

By: L. Anderson n, J. Holt n, E. Heugten n & D. Poole n

author keywords: heat stress cytokine
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021

2020 journal article

Evaluation of Resistance to Fescue Toxicosis in Purebred Angus Cattle Utilizing Animal Performance and Cytokine Response

TOXINS, 12(12).

By: D. Poole n, K. Mayberry n, M. Newsome n, R. Poole n, J. Galliou n, P. Khanal n, M. Poore n, N. Serao n

author keywords: fescue toxicosis; genetic tolerance; cytokines; cow productivity
MeSH headings : Animal Feed / analysis; Animal Feed / toxicity; Animals; Behavior, Animal / drug effects; Behavior, Animal / physiology; Cattle; Cattle Diseases / chemically induced; Cattle Diseases / metabolism; Cattle Diseases / microbiology; Cytokines / metabolism; Ergot Alkaloids / analysis; Ergot Alkaloids / toxicity; Herbivory / drug effects; Herbivory / physiology; Poaceae / microbiology; Poaceae / toxicity
TL;DR: Findings from this study support the proposed fescue toxicosis selection method, could accurately distinguish between tolerant and susceptible animals based on the performance parameters in cattle chronically exposed to ergot alkaloids, and provides evidence to warrant additional analysis to examine the impact of ergotAlkaloids on immune responsiveness in cattle experiencing fescues toxicosis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021

2020 journal article

Evaluation of a commercial genetic test for fescue toxicosis in pregnant Angus beef cattle

TRANSLATIONAL ANIMAL SCIENCE, 4(4).

By: J. Galliou n, P. Khanal n, K. Mayberry n, M. Poore n, D. Poole n & N. Serao n

author keywords: Bos taurus; Epichloe coenophiala; fescue toxicity; host genetics; T-Snip test
TL;DR: Results indicate that the T-Snip test may be predictive of cow performance (aBWd, aBCSd, and adjWW) in an endophyte-infected tall fescue environment. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021

2020 article

In Utero Exposure of Ergot Alkaloids does not Impact Heifer Growth and Reproductive Performance.

Haimon, M. K. L., Brown, A. R., Poore, M. H., & Poole, D. H. (2020, November). JOURNAL OF ANIMAL SCIENCE, Vol. 98, pp. 44–44.

By: M. Haimon n, A. Brown n, M. Poore n & D. Poole n

TL;DR: While consumption of EI fescue during gestation impacts cow performance and onset of puberty in heifers, it has minimal effect on heifer growth and reproductive development and performance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 1, 2021

2020 journal article

Physiological response, function of sweat glands, and hair follicle cycling in cattle in response to fescue toxicosis and hair genotype

Journal of Animal Science, 98(3).

By: J. Eisemann n, M. Ashwell n, T. Devine n, D. Poole n, M. Poore n & K. Linder n

author keywords: beef heifers; hair follicle; prolactin receptor; slick hair trait; sweat gland; tall fescue
MeSH headings : Animal Feed; Animals; Cattle / genetics; Cattle / physiology; Cattle Diseases / microbiology; Cattle Diseases / physiopathology; Diet / veterinary; Endophytes / physiology; Female; Festuca / microbiology; Gene Expression Regulation; Genotype; Hair; Hair Follicle / physiology; Heat-Shock Response; Mycotoxicosis / microbiology; Mycotoxicosis / physiopathology; Mycotoxicosis / veterinary; Plant Poisoning / microbiology; Plant Poisoning / physiopathology; Plant Poisoning / veterinary; Sweat Glands / physiology
TL;DR: EI fescue resulted in increased ST, changes in hair follicle cycling that support greater hair growth, and decreased TEWL for heifers with the W compared to S genotype suggesting greater heat stress in response to EI. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 1, 2020

2019 journal article

111 Changes in proinflammatory cytokines and chemokines in beef steers chronically exposed to endophyte-infected tall fescue seed

Journal of Animal Science, 97(Supplement_1), 42–43.

By: A. Brown n, R. Poole n, M. Jackson n, M. Poore n, C. Pickworth n & D. Poole n

author keywords: fescue toxicity; cytokines; protein supplementation; immunity; beef steers
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 12, 2019

2019 journal article

47 Interaction of dietary protein and endophyte- infected Tall Fescue seed in stocker steers on finishing phase performance and carcass traits

Journal of Animal Science, 97(Supplement_1), 83–83.

By: M. Davis n, R. Poole n, M. Poore n, D. Poole n & C. Pickworth n

author keywords: fescue toxicity; stocker cattle; dietary protein
TL;DR: Finishing growth and carcass characteristics were not affected by exposure to ergot alkaloids at weaning as much as dietary protein when cattle had a background period prior to feedlot entry. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 12, 2019

2019 journal article

Effects of endophyte-infected tall fescue seed and protein supplementation on stocker steers: I. Growth performance and hemodynamic responses

Journal of Animal Science, 97(9), 3776–3785.

By: R. Poole n, C. Womble n, M. Poore n, D. Poole n & C. Pickworth n

author keywords: fescue toxicosis; growth; hemodynamics; stocker steers
MeSH headings : Animal Feed / analysis; Animals; Body Weight; Cattle / growth & development; Cattle / physiology; Cattle Diseases / prevention & control; Diet / veterinary; Dietary Supplements / analysis; Endophytes / physiology; Ergot Alkaloids / adverse effects; Hemodynamics; Lolium / chemistry; Lolium / microbiology; Male; Plant Poisoning / prevention & control; Plant Poisoning / veterinary; Prolactin / blood; Proteins / analysis; Random Allocation; Seeds / chemistry; Seeds / microbiology
TL;DR: Based on the data, exposure to low to moderate levels of ergot alkaloids during the stocker phase had a negative impact on hemodynamic responses and supplemental CP had minimal impact to alleviate symptoms and feeding additional protein above established requirements is not expected to help alleviate fescue toxicosis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: November 4, 2019

2019 journal article

Effects of endophyte-infected tall fescue seed and protein supplementation on stocker steers: II. Adaptive and innate immune function

Journal of Animal Science, 97(10), 4160–4170.

By: R. Poole n, A. Brown n, M. Poore n, C. Pickworth n & D. Poole n

author keywords: beef steers; ergovaline; immunity; vaccination
MeSH headings : Animal Feed / analysis; Animals; Cattle / immunology; Dietary Supplements / analysis; Endophytes / physiology; Ergotamines / pharmacology; Festuca / chemistry; Festuca / microbiology; Immunity, Innate; Male; Plant Poisoning / veterinary; Vaccines / immunology
TL;DR: Steers exposed to ergovaline have an increase in pro- and anti-inflammatory cytokines and supplemental CP had minimal impact to mitigate this response, however, in the current study exposure to ergovine had little to no effect on adaptive immunity and response to vaccination. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: November 25, 2019

2019 article

Evaluation of cytokine response as an indicator of genetic resistance to fescue toxicosis in purebred Angus cattle.

Mayberry, K., Poole, R. K., Newsome, M. K. A., Khanal, P., Poore, M. H., Serao, N. V. L., & Poole, D. H. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 45–46.

By: K. Mayberry n, R. Poole n, M. Newsome n, P. Khanal n, M. Poore n, N. Serao*, D. Poole n

author keywords: fescue toxicosis; genetic tolerance; cytokines
TL;DR: Evaluating the cytokine response of cows deemed either tolerant or susceptible to endophyte-infected fescue found greater concentrations of GASP-1, VEGF-A, and IL-4 in tolerant compared to susceptible cattle may mitigate the detrimental effects of fescUE toxicosis, including suppressed PRL and vasoconstriction, leading to improved animal performance in a fescues environment. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 article

Genes and functions associated with tolerance to fescue toxicosis in Angus cows

Khanal, P., Sanglard, L. P., Mayberry, K., Sommer, J., Poore, M. H., Poole, D. H., & Serao, N. V. L. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 167–167.

By: P. Khanal n, L. Sanglard*, K. Mayberry n, J. Sommer n, M. Poore n, D. Poole n, N. Serao*

author keywords: fescue toxicosis; differentially expressed genes; tolerance
TL;DR: Enrichment analysis showed that DEG between genetic groups have general functions, such as metabolic, biosynthetic, and catabolic processes, as well as DNA and RNA-related functions,such as translation, transcription, and repair. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 review

Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species

[Review of ]. TOXINS, 11(6).

By: R. Poole n & D. Poole n

author keywords: ergot alkaloids; livestock; reproduction
MeSH headings : Animals; Brain / drug effects; Brain / physiology; Ergot Alkaloids / toxicity; Female; Festuca; Lactation; Livestock; Ovary / drug effects; Ovary / physiology; Plant Poisoning / complications; Plant Poisoning / veterinary; Pregnancy; Reproduction / drug effects; Uterus / drug effects; Uterus / physiology
TL;DR: This review will summarize the various effects of ergot alkaloids on female reproduction in grazing livestock species and investigate the physiological and cellular mechanisms of these reproductive failures associated with fescue toxicosis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 5, 2019

2019 journal article

Impact of slick hair trait on physiological and reproductive performance in beef heifers consuming ergot alkaloids from endophyte-infected tall fescue

JOURNAL OF ANIMAL SCIENCE, 97(4), 1456–1467.

By: R. Poole n, T. Devine n, K. Mayberry n, J. Eisemann n, M. Poore n, N. Long*, D. Poole n

author keywords: fescue toxicosis; slick hair trait; beef heifer; ovary
MeSH headings : Animal Feed / analysis; Animals; Body Weight / drug effects; Cattle / physiology; Corpus Luteum / physiology; Diet / veterinary; Endophytes / physiology; Ergot Alkaloids / adverse effects; Estrus / drug effects; Female; Festuca / microbiology; Hair; Ovarian Follicle / physiology; Ovary / physiology; Phenotype; Pregnancy; Random Allocation; Reproduction / drug effects
TL;DR: The slick hair mutation appears to aid in offsetting the physiological symptoms associated with fescue toxicosis and helps to improve reproductive performance in heifers experiencing fescUE toxicosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 22, 2019

2019 article

Interaction of dietary protein and endophyte-infected Tall Fescue seed in stocker steers on finishing phase performance and carcass traits.

Davis, M. E., Poole, R. K., Poore, M. H., Poole, D. H., & Pickworth, C. L. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 38–38.

By: M. Davis n, R. Poole n, M. Poore n, D. Poole n & C. Pickworth n

Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 article

Long term impact of ergot alkaloids on fetal heifer development and subsequent growth and reproductive performance.

Jackson, M. K. L., Newsome, M. K. A., Brown, A. R., Poole, R. K., Dudley, H. B., Poore, M. H., & Poole, D. H. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 46–46.

By: M. Jackson n, M. Newsome n, A. Brown n, R. Poole n, H. Dudley n, M. Poore n, D. Poole n

author keywords: fetal programming; heifer development; fescue
TL;DR: While consumption of EI fescue impacts cow performance, calf birthweight, and ratio of cotyledon to placenta weight, it has minimal effect on postnatal growth and development through 10 mo of age, further studies are needed to determine the impact on heifer reproductive performance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 article

Renovating toxic-infected tall fescue pastures for profitability, animal performance, and soil health.

Ingram, S., Poore, M. H., & Poole, D. H. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 37–38.

By: S. Ingram n, M. Poore n & D. Poole n

author keywords: tall fescue; renovation; cover crop
TL;DR: Data suggests agronomic and animal performance for 3-CM and 3-SM were improved compared to C and could partially alleviate initial renovation costs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 article

Renovating toxic-infected tall fescue pastures for profitability, animal performance, and soil health.

Ingram, S., Poore, M. H., & Poole, D. H. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 20–20.

By: S. Ingram n, M. Poore n & D. Poole n

author keywords: Tall fescue; renovation; cover crop
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 article

Timing of progesterone exposure effects pregnancy rates following fixed time artificial insemination in postpartum beef cows.

Smith, A. L., Poole, R. K., Mayberry, K., Newsome, M. K. A., Dudley, H. B., & Poole, D. H. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 43–44.

By: A. Smith n, R. Poole n, K. Mayberry n, M. Newsome n, H. Dudley n & D. Poole n

author keywords: fFixed timed AI; postpartum beef cows; corpus luteum
TL;DR: Incorporating a presynchronization program to ensure the presence of a functional CL at the start of a FTAI protocol may improve pregnancy success in postpartum beef cows. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2019 article

Timing of progesterone exposure effects pregnancy rates following fixed timed artificial insemination in postpartum beef cows.

Smith, A. L., Poole, R. K., Mayberry, K., Newsome, M. K. A., Dudley, H. B., & Poole, D. H. (2019, July). JOURNAL OF ANIMAL SCIENCE, Vol. 97, pp. 85–85.

By: A. Smith n, R. Poole n, K. Mayberry n, M. Newsome n, H. Dudley* & D. Poole n

author keywords: fixed timed AI; postpartum beef cows; corpus luteum
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 12, 2019

2018 journal article

142 Impact of Protein Supplementation on Physiological Response of Steers Consuming Endophyte-Infected Tall Fescue Seed.

Journal of Animal Science, 96(suppl_1), 75–76.

By: C. Womble n, R. Poole n, D. Poole n & C. Pickworth n

author keywords: protein supplementation; beef steers; fescue toxicity
Sources: Web Of Science, NC State University Libraries, Crossref
Added: November 26, 2018

2018 journal article

41 “Effect of Protein Supplementation on Immune Response of Weaned Steers Consuming Endophyte-Infected Tall Fescue Seed”.

Journal of Animal Science, 96(suppl_1), 21–22.

By: R. Poole n, C. Womble n, C. Pickworth n & D. Poole n

author keywords: protein supplementation; fescue toxicity; immunity
Sources: Web Of Science, NC State University Libraries, Crossref
Added: November 26, 2018

2018 journal article

A two-injection prostaglandin F-2 alpha presynchronization treatment decreases pregnancy rates of cycling replacement beef heifers

TRANSLATIONAL ANIMAL SCIENCE, 3(1), 456–463.

By: R. Monn n, R. Poole n, J. Mackey n, K. Mayberry n, H. Dudley n, M. Alley*, D. Poole n

author keywords: cattle; estrous synchronization; heifer growth; pregnancy
Sources: Web Of Science, NC State University Libraries
Added: July 8, 2019

2018 journal article

Ergot alkaloids induce vasoconstriction of bovine uterine and ovarian blood vessels

JOURNAL OF ANIMAL SCIENCE, 96(11), 4812–4822.

By: D. Poole n, S. Lyons n, R. Poole n & M. Poore n

author keywords: fescue toxicosis; ergovaline; reproductive tract
MeSH headings : Animals; Cattle / physiology; Endophytes; Epichloe / physiology; Ergot Alkaloids / chemistry; Ergot Alkaloids / pharmacology; Ergotamines; Estrous Cycle / drug effects; Female; Festuca / chemistry; Festuca / microbiology; Heart Rate / drug effects; Hemodynamics / drug effects; Ovary / blood supply; Pregnancy; Random Allocation; Reproduction / drug effects; Uterus / blood supply; Vasoconstriction / drug effects
TL;DR: Reduction in blood flow to the reproductive organs during critical times in the estrous cycle may contribute to the reduced ovarian function and pregnancy rates associated with fescue toxicosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: December 10, 2018

2018 article

Evaluation of Angus Calf Performance Based on Dams Tolerance or Susceptibility to Fescue Toxicosis.

Mayberry, K., Khanal, P., Poore, M. H., Serao, N. V. L., & Poole, D. H. (2018, March). JOURNAL OF ANIMAL SCIENCE, Vol. 96, pp. 55–55.

By: K. Mayberry n, P. Khanal n, M. Poore n, N. Serao* & D. Poole n

author keywords: calf performance; cow productivity; fescue toxicosis
Sources: Web Of Science, NC State University Libraries
Added: November 26, 2018

2018 article

Grazing Novel or Endophyte-Infected Tall Fescue during Mid-Gestation Impacts Cow Performance.

Newsome, M. A., Monn, R. E., Mayberry, K., Poole, R. K., Young, Z., Poore, M. H., & Poole, D. H. (2018, March). JOURNAL OF ANIMAL SCIENCE, Vol. 96, pp. 13–13.

By: M. Newsome n, R. Monn n, K. Mayberry n, R. Poole n, Z. Young n, M. Poore n, D. Poole n

author keywords: beef cows; fescue toxicosis; novel endophyte
Sources: Web Of Science, NC State University Libraries
Added: November 26, 2018

2018 article

Implementing Shade and Slick Hair Phenotypes Improves Heifer Performance

Monn, R. E., Shea, T. P., Mayberry, K., Freeman, S. R., Poole, D. H., & Poore, M. H. (2018, March). JOURNAL OF ANIMAL SCIENCE, Vol. 96, pp. 79–80.

By: R. Monn n, T. Shea n, K. Mayberry n, S. Freeman n, D. Poole n & M. Poore n

author keywords: Beef Heifers; SLICK hair Phenotype; Silvopasture
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 26, 2018

2017 journal article

Toll-like receptor and related cytokine mRNA expression in bovine corpora lutea during the oestrous cycle and pregnancy

REPRODUCTION IN DOMESTIC ANIMALS, 52(3), 495–504.

By: J. Gadsby n, A. Nipper n, H. Faircloth n, . M. D'Annibale-Tolhurst, J. Chang n, P. Farin n, I. Sheldon*, D. Poole n

MeSH headings : Animals; Cattle; Corpus Luteum / drug effects; Corpus Luteum / metabolism; Cytokines / genetics; Estrous Cycle / genetics; Estrous Cycle / metabolism; Female; Gene Expression Regulation; Lipopolysaccharides / pharmacology; Luteolysis / genetics; Pregnancy; Pregnancy, Animal / genetics; Pregnancy, Animal / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Toll-Like Receptors / genetics; Toll-Like Receptors / metabolism
TL;DR: Based on data, one or more of the TLRs found within the CL may play a role in luteolysis, perhaps via pro-inflammatory cytokine mRNA expression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Anti-Mullerian hormone (AMH) receptor type II expression and AMH activity in bovine granulosa cells

THERIOGENOLOGY, 86(5), 1353–1360.

By: D. Poole*, O. Ocon-Grove* & A. Johnson*

author keywords: Follicle development; Granulosa cell proliferation; Bone morphogenetic proteins
MeSH headings : Animals; Anti-Mullerian Hormone / metabolism; Cattle / physiology; Cell Proliferation; Cells, Cultured; Female; Gene Expression Regulation; Granulosa Cells / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptors, Peptide / genetics; Receptors, Peptide / metabolism; Receptors, Transforming Growth Factor beta / genetics; Receptors, Transforming Growth Factor beta / metabolism
TL;DR: Results from these studies indicate that AMH signaling plays a role in both regulating granulosa cell proliferation and preventinggranulosa cells from 5- to 8-mm follicles from undergoing premature differentiation before follicle selection. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Effect of protein supplementation and forage allowance on the growth and reproduction of beef heifers grazing stockpiled tall fescue

JOURNAL OF ANIMAL SCIENCE, 94(4), 1677–1688.

By: S. Lyons n, A. Shaeffer n, M. Drewnoski*, M. Poore n & D. Poole n

author keywords: beef heifer development; stockpiled fescue; supplementation
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Blood Urea Nitrogen; Body Weight / drug effects; Cattle / physiology; Diet / veterinary; Dietary Proteins / administration & dosage; Dietary Proteins / pharmacology; Dietary Supplements; Female; Festuca / metabolism; Minerals; Pregnancy; Reproduction; Seasons; Sexual Maturation; Weight Gain / drug effects
TL;DR: Overall, feeding a protein supplement or providing extra forage increased gain and interacted to increase BCS but did not have an effect on reproductive performance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Site of PGF 2α injection does not alter effectiveness of the Select Synch + controlled internal drug release and timed artificial insemination protocol

Theriogenology, 87, 161–166.

By: C. Pickworth n, L. Bell n, W. Greene*, C. Whisnant n & D. Poole n

author keywords: Estrus synchronization; Quality assurance; Beef production; Injection site
MeSH headings : Animals; Cattle / physiology; Dinoprost / administration & dosage; Dinoprost / pharmacology; Drug Administration Schedule; Estrus Detection / instrumentation; Female; Gonadotropin-Releasing Hormone / administration & dosage; Gonadotropin-Releasing Hormone / pharmacology; Insemination, Artificial / veterinary; Pregnancy; Progesterone / pharmacology; Time Factors
TL;DR: Overall, altering the location of the PGF2α injection during ES did not change circulating hormone concentrations at AI or pregnancy rates; therefore, cattle producers should follow Beef Quality Assurance guidelines when administering ES protocols. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Comparison of pregnancy rates in beef cattle after a fixedtime Al with once-or twice-used controlled internal drug release devices

THERIOGENOLOGY, 85(3), 447–451.

By: A. Muth-Spurlock n, D. Poole n & C. Whisnant n

author keywords: Controlled internal drug release; Artificial insemination; Estrus synchronization; Beef cattle
MeSH headings : Animals; Cattle / physiology; Dinoprost / administration & dosage; Dinoprost / adverse effects; Drug Delivery Systems / instrumentation; Drug Delivery Systems / veterinary; Estrus Synchronization / methods; Female; Food Quality; Infusion Pumps, Implantable; Injections, Intramuscular / adverse effects; Insemination, Artificial / methods; Insemination, Artificial / veterinary; Pregnancy; Pregnancy Rate; Progesterone / blood; Red Meat
TL;DR: Evidence is provided that although concentration of progesterone is decreased in animals treated with a twice-used CIDR device, there is still a sufficient release of progestersone from the device to effectively synchronize estrus without adversely affecting the fertility of a herd. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Progesterone effects on lymphocytes may be mediated by membrane progesterone receptors

Journal of Reproductive Immunology, 95(1-2), 15–26.

By: K. Ndiaye*, D. Poole*, S. Walusimbi*, M. Cannon*, K. Toyokawa*, S. Maalouf*, J. Dong, P. Thomas, J. Pate*

author keywords: Lymphocytes; Progesterone; mPR; PGRMC1; Corpus luteum
MeSH headings : Animals; Cattle; Cell Membrane / immunology; Cell Membrane / metabolism; Corpus Luteum / cytology; Corpus Luteum / immunology; Corpus Luteum / metabolism; Female; Gene Expression Regulation / drug effects; Gene Expression Regulation / immunology; Interleukin-2 Receptor alpha Subunit / immunology; Interleukin-2 Receptor alpha Subunit / metabolism; Progesterone / immunology; Progesterone / metabolism; Progesterone / pharmacology; RNA, Messenger / biosynthesis; RNA, Messenger / immunology; Receptors, Progesterone / immunology; Receptors, Progesterone / metabolism; T-Lymphocytes / cytology; T-Lymphocytes / immunology; T-Lymphocytes / metabolism
TL;DR: Progesterone induces specific and rapid functional effects on T lymphocytes in the absence of PGR, and a specific, saturable, and single progesterone binding site with a steroid specificity characteristic of mPRs was demonstrated by saturation and competitive binding assays using T lymphocyte membranes. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: June 6, 2020

2007 journal article

Microarray analysis of gene expression in granulosal cells from persistent follicles in cattle

Animal Reproduction Science, 104(2-4), 405–413.

By: B. Lingenfelter*, R. Dailey, E. Inskeep, M. Vernon, D. Poole*, J. Rhinehart, J. Yao

author keywords: oocyte; cow; granulosal cells; persistent follicle
MeSH headings : Animals; Cattle / genetics; Cattle / metabolism; Female; Gene Expression Profiling; Granulosa Cells / metabolism; Granulosa Cells / physiology; Oligonucleotide Array Sequence Analysis / veterinary; Ovarian Follicle / cytology; Ovarian Follicle / metabolism; Ovarian Follicle / physiology; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction / veterinary
TL;DR: Data suggest that aged granulosal cells may have a reduced capacity to provide energy and amino acids to the oocyte, as revealed in a direct comparison microarray experiment using a bovine long oligo array representing approximately 8400 known genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2006 journal article

Changes of maternal transcripts in oocytes from persistent follicles in cattle

Molecular Reproduction and Development, 74(3), 265–272.

By: B. Lingenfelter*, R. Dailey*, E. Inskeep*, M. Vernon*, D. Poole*, J. Rhinehart*, J. Yao*

author keywords: cow; gene expression; embryonic development
MeSH headings : Animals; Cattle; Estrus / metabolism; Female; Oocytes / metabolism; Ovarian Follicle / metabolism; RNA, Messenger / metabolism; Transcription, Genetic
TL;DR: The data indicate that persistence of a follicle leads to altered abundances of mRNA for genes important for regulation of transcription and protein translation in the oocyte, which could compromise development of early embryos in cows that ovulate a persistent follicle. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 2, 2020

Employment

Updated: June 20th, 2024 10:57

2022 - present

North Carolina State University Raleigh, US
Professor Animal Science

2021 - present

North Carolina State University Raleigh, US
Co-Chair Food Animal Scholars Program Animal Science

2017 - 2022

NC State University Raleigh, NC, US
Associate Professor Animal Science

2011 - 2017

North Carolina State University Raleigh, NC, US
Assistant Professor Animal Science

2009 - 2011

Pennsylvania State University University Park, PA, US
Post Doctoral Fellow Poutlry Science

Education

Updated: July 2nd, 2018 09:20

2005 - 2009

The Ohio State University Columbus, Ohio, US
Doctorate of Philosophy Animal Science

2002 - 2005

West Virginia University Morgantown, WV, US
Master of Science in Reproductive Physiology Animal and Nutritional Sciences

2000 - 2002

West Virginia University Morgantown, WV, US
Bachelors of Science Animal and Nutritional Sciences

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