Dylan DeProspero

College of Veterinary Medicine

Works (4)

Updated: July 5th, 2023 14:42

2021 journal article

A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat

ORPHANET JOURNAL OF RARE DISEASES, 16(1).

By: K. Meurs n , B. Williams n, D. DeProspero n, S. Friedenberg*, D. Malarkey*, J. Ezzell *, B. Keene n, D. Adin n, T. DeFrancesco n , S. Tou n

author keywords: Hypertrophic cardiomyopathy; ALMS1; Feline; Mitogenic; Sphynx
MeSH headings : Animals; Cardiomyopathy, Hypertrophic / genetics; Cats / genetics; Cell Cycle Proteins / genetics; Exons; Mice; Mutation / genetics
TL;DR: This study demonstrates a novel form of cardiomyopathy associated with ALMS1 in the cat, and suggests that variants in genes involved with cardiac development and cell regulation, like the AL MS1 gene, may deserve further consideration for association with familial hypertrophic cardiopathy. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: April 12, 2021

2021 journal article

A novel career development course for animal science students pursuing veterinary college admissions

TRANSLATIONAL ANIMAL SCIENCE, 5(3).

By: S. Trivedi n, J. Clark n, D. Deprospero n, K. Royal n  & M. See  n

author keywords: career development course; pre-professional identity development; pre-veterinary advising; pre-veterinary curriculum; self-efficacy; vicarious experiences
TL;DR: The results of the study showed that students experienced significant gains in self-appraisal, gathering occupational information, and planning and problem-solving as well as experienced a decrease in five misperceptions about veterinary admissions. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: November 8, 2021

2021 journal article

Myxomatous mitral valve disease in Miniature Schnauzers and Yorkshire Terriers: 134 cases (2007-2016)

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 259(12), 1428–1432.

By: D. DeProspero n, . Kerry A. O'Donnell n, T. DeFrancesco n , B. Keene n, S. Tou n, D. Adin n, C. Atkins n, K. Meurs n 

MeSH headings : Animals; Dog Diseases / epidemiology; Dogs; Heart Valve Diseases / veterinary; Humans; Mitral Valve; Mitral Valve Prolapse / epidemiology; Mitral Valve Prolapse / veterinary; Prospective Studies
TL;DR: Features of the disease among Miniature Schnauzers and Yorkshire Terriers were similar, but there were also a few discernable differences between these 2 breeds and from historical findings for dogs with MMVD of other breeds. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 21, 2022

2020 journal article

A mutation in MTM1 causes X-Linked myotubular myopathy in Boykin spaniels

Neuromuscular Disorders, 30(5), 353–359.

By: N. Olby n , S. Friedenberg*, K. Meurs n , D. DeProspero n, J. Guevar n, J. Lau  n, O. Yost n, L. Guo *, G. Shelton *

author keywords: Canine; Centronuclear myopathy; Myotubularin myopathy
MeSH headings : Animals; Dogs; Male; Myopathies, Structural, Congenital / genetics; Myopathies, Structural, Congenital / pathology; Myopathies, Structural, Congenital / physiopathology; Pedigree; Phenotype; Protein Tyrosine Phosphatases, Non-Receptor / genetics
TL;DR: The purpose of this study was to report the findings of clinical and genetic evaluation of a 3-month old male Boykin spaniel that presented with progressive weakness that causes a severe form of X-linked myotubular myopathy, comparable to the human counterpart. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: June 29, 2020

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