Daniel Haller
College of Engineering
Works (3)
Updated: January 26th, 2024 05:00
2023 journal article
Particulate matter composition drives differential molecular and morphological responses in lung epithelial cells
PNAS NEXUS, 3(1).
author keywords: systems biology; transcriptomics; cell morphology; cell phenotyping; air pollution
TL;DR:
The results demonstrate that quantitative measurement of cellular morphology provides a robust approach to gauge the effects of environmental stressors on biological systems and determine cellular susceptibilities to pollution.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
Source: Web Of Science
Added: January 22, 2024
2022 journal article
A Novel Method of Inducible Directed Evolution to Evolve Complex Phenotypes
BIO-PROTOCOL, 12(20).
author keywords: Directed Evolution; Inducible Systems; Complex Phenotypes; Pathways; Gene Clusters; P1 Phage; Mutagenesis
TL;DR:
A new directed evolution method (Inducible Directed Evolution, IDE) is developed that combines the specificity and throughput of recent continuous directed evolution methods with the ease of ALE, which enables long DNA sequences to be mutated in a high throughput manner via a simple series of incubation steps.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 12, 2023
2022 article
Inducible directed evolution of complex phenotypes in bacteria
Al'Abri, I. S., Haller, D. J., Li, Z., & Crook, N. (2022, February 12). NUCLEIC ACIDS RESEARCH, Vol. 2.
MeSH headings : Bacteria / genetics; Bacteria / metabolism; Bacteria / virology; Bacteriophages / genetics; Directed Molecular Evolution / methods; Mutagenesis; Phenotype; Plasmids / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 13, 2022
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