Daniel Haller

College of Engineering

Works (3)

Updated: January 26th, 2024 05:00

2023 journal article

Particulate matter composition drives differential molecular and morphological responses in lung epithelial cells

PNAS NEXUS, 3(1).

By: S. Engels *, P. Kamat *, G. Pafilis *, Y. Li *, A. Agrawal *, D. Haller n, J. Phillip *, L. Contreras *

author keywords: systems biology; transcriptomics; cell morphology; cell phenotyping; air pollution
TL;DR: The results demonstrate that quantitative measurement of cellular morphology provides a robust approach to gauge the effects of environmental stressors on biological systems and determine cellular susceptibilities to pollution. (via Semantic Scholar)
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Added: January 22, 2024

2022 journal article

A Novel Method of Inducible Directed Evolution to Evolve Complex Phenotypes

BIO-PROTOCOL, 12(20).

By: I. Al'Abri n, Z. Li n, D. Haller n & N. Crook n 

author keywords: Directed Evolution; Inducible Systems; Complex Phenotypes; Pathways; Gene Clusters; P1 Phage; Mutagenesis
TL;DR: A new directed evolution method (Inducible Directed Evolution, IDE) is developed that combines the specificity and throughput of recent continuous directed evolution methods with the ease of ALE, which enables long DNA sequences to be mutated in a high throughput manner via a simple series of incubation steps. (via Semantic Scholar)
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Added: June 12, 2023

2022 article

Inducible directed evolution of complex phenotypes in bacteria

Al'Abri, I. S., Haller, D. J., Li, Z., & Crook, N. (2022, February 12). NUCLEIC ACIDS RESEARCH, Vol. 2.

By: I. Al'Abri n, D. Haller n, Z. Li n & N. Crook n 

MeSH headings : Bacteria / genetics; Bacteria / metabolism; Bacteria / virology; Bacteriophages / genetics; Directed Molecular Evolution / methods; Mutagenesis; Phenotype; Plasmids / genetics
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Added: February 13, 2022

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