Works (135)

Updated: February 2nd, 2024 05:00

2022 report

Combinations of carnosine and zinc for the treatment and prevention of viral infections

(Patent No. WO2022005848A1).

By: D. Nelson

Source: NC State University Libraries
Added: May 14, 2022

2022 article

Ramatroban for chemoprophylaxis and treatment of COVID-19: David takes on Goliath

Chiang, K. C., Rizk, J. G., Nelson, D. J., Krishnamurti, L., Subbian, S., Imig, J. D., … Gupta, A. (2022, February 24). EXPERT OPINION ON THERAPEUTIC TARGETS, Vol. 2.

By: K. Chiang*, J. Rizk*, D. Nelson n, L. Krishnamurti*, S. Subbian*, J. Imig*, I. Khan*, S. Reddy*, A. Gupta*

co-author countries: United States of America 🇺🇸
author keywords: Ramatroban; pharmacotherapy; COVID-19; long-haul COVID; thromboinflammation; thromboxane A(2); prostaglandin D-2; ARDS; interferon; lymphopenia; SARS-CoV-2; acute kidney injury; fibrosis; ischemia; platelets; immunomodulator; anti-platelet; IL-13; thrombosis; antithrombotic; cyclooxygenase (COX)
MeSH headings : Animals; COVID-19 / complications; Carbazoles / therapeutic use; Chemoprevention; Humans; Inflammation / drug therapy; SARS-CoV-2; Sulfonamides / therapeutic use; Thrombosis / drug therapy; Post-Acute COVID-19 Syndrome; COVID-19 Drug Treatment
Sources: Web Of Science, ORCID
Added: March 7, 2022

2021 report

Magnesium biotinate compositions and methods of use

(U.S. Patent Pending No. US20180071264A1).

By: D. Nelson & J. Komorowski

Source: NC State University Libraries
Added: May 14, 2022

2021 report

Pharmaceutical quality strontium L-lactate. U.S

(Patent No. US11026906B2).

By: D. Nelson

Source: NC State University Libraries
Added: July 27, 2021

2020 report

Drug delivery via ferric citrate

[U.S. Patent Pending].

By: D. Nelson

Source: NC State University Libraries
Added: May 14, 2022

2020 report

Liquid concentrate of calcium and magnesium

(Patent No. WO2020210608A1).

By: D. Nelson

Source: NC State University Libraries
Added: May 14, 2022

2020 report

Pharmaceutical quality strontium L-lactate

(Republic of South Africa Patent No. 2019/02258).

By: D. Nelson

Source: NC State University Libraries
Added: July 27, 2021

2019 report

Pharmaceutical quality strontium L-lactate

(Patent No. US10463636B2).

By: D. Nelson

Source: NC State University Libraries
Added: July 27, 2021

2018 report

Magnesium biotinate compositions and methods of use

(U.S. Patent No. 20180071264).

By: D. Nelson & J. Komorowski

Source: NC State University Libraries
Added: July 28, 2021

2018 report

Magnesium picolinate compositions and methods of use

(US Patent No. US20180098976).

By: D. Nelson & J. Komorowski

Source: NC State University Libraries
Added: July 28, 2021

2014 report

Phosphorus binder composition for treatment of hyperphosphatemia

(U.S. Patent No. US8759398B2).

By: D. Nelson

Source: NC State University Libraries
Added: July 28, 2021

2013 chapter

Blood Substitutes: Hemoglobin-Based Oxygen Carriers

In J. Swarbrick (Ed.), Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition (4th ed., pp. 330–341).

By: D. Nelson*

Ed(s): J. Swarbrick

Source: Crossref
Added: July 27, 2021

2012 report

Combined calcium, magnesium, and Vitamin D supplements

(U.S. Patent No. 8324191).

By: D. Nelson & W. Holberg

Source: NC State University Libraries
Added: July 29, 2021

2012 report

Iron preparation suitable for pharmaceutical formulation and process for the preparation thereof

(U.S. Patent No. US8178709B2).

By: D. Nelson & B. Mosley

Source: NC State University Libraries
Added: July 28, 2021

2012 conference paper

Phosphate Binder Comparison: Sevelamer Carbonate & CaSuccinate/MgLipoate

Nelson, D. J., Holberg, W. C., Hruska, K. A., & Fang, Y. (2012, November). Phosphate Binder Comparison: Sevelamer Carbonate & CaSuccinate/MgLipoate. Presented at the American Society of Nephrology 2012 National Meeting (Kidney Week 2012), San Diego, CA.

By: D. Nelson, W. Holberg, K. Hruska & Y. Fang

Event: American Society of Nephrology 2012 National Meeting (Kidney Week 2012) at San Diego, CA

Source: NC State University Libraries
Added: July 29, 2021

2011 report

Phosphorus binder for treatment of kidney disease

(U.S. Patent No. 8034833).

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2011 report

Phosphorus binder for treatment of kidney disease

(U.S. Patent No. 7862836).

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2011 report

Stable, water-insoluble R-(+)-alpha-lipoic acid salt useful for the treatment of diabetes mellitus and its co-morbidities

(U.S. Patent No. 8222432).

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2009 journal article

Comparing Soluble Ferric Pyrophosphate to Common Iron Salts and Chelates as Sources of Bioavailable Iron in a Caco-2 Cell Culture Model

Journal of Agricultural and Food Chemistry, 57(11), 5014–5019.

By: L. Zhu*, R. Glahn*, D. Nelson* & D. Miller*

co-author countries: United States of America 🇺🇸
author keywords: Soluble ferric pyrophosphate; ferritin; ascorbic acid; pH; divalent metal ions; Caco-2 cells; iron bioavailability
MeSH headings : Biological Availability; Caco-2 Cells; Diphosphates / chemistry; Diphosphates / pharmacokinetics; Humans; Iron / chemistry; Iron / pharmacokinetics; Iron Chelating Agents / chemistry; Iron Chelating Agents / pharmacokinetics; Iron, Dietary / pharmacokinetics; Models, Biological; Phytic Acid / chemistry; Solubility; Tannins / chemistry
Sources: Crossref, ORCID
Added: July 25, 2021

2009 report

Non-hygroscopic L-carnitine salts

(U.S. Patent No. 7572832).

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2008 report

Methods for the preparation and formulation and use of lithium valproate

(U.S. Patent No. 7790921).

By: N. Malkar & D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2007 report

Methods for the preparation and formulation and use of lithium valproate

(U.S. Patent No. 7449598).

By: N. Malkar & D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2007 report

Methods for the preparation and formulation of L-carnitine valproate salts

(U.S. Patent No. 7456216).

By: N. Malkar & D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2007 report

Synthesis of hydrazine and chlorinated derivatives of bicyclic pyridazines

(U.S. Patent No. 7220858).

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2007 journal article

Uptake and reduction of α-lipoic acid by human erythrocytes

Clinical Biochemistry, 40(15), 1135–1142.

By: J. May*, Z. Qu* & D. Nelson*

co-author countries: United States of America 🇺🇸
author keywords: lipoic acid; dehydroascorbic acid; phenylarsine oxide; ferricyanide; oxidant stress; pyridine nueleotide disulfide reductase; human erythrocytes
Sources: Crossref, ORCID
Added: July 28, 2021

2006 journal article

Cellular disulfide-reducing capacity: An integrated measure of cell redox capacity

Biochemical and Biophysical Research Communications, 344(4), 1352–1359.

By: J. May*, Z. Qu* & D. Nelson*

co-author countries: United States of America 🇺🇸
author keywords: alpha-lipoic acid; alpha-lipoamide; redox regulation; dehydroascorbate; GSH; oxidant stress; EA.hy926 endothelial cells
MeSH headings : Cell Line; Disulfides / metabolism; Dithionitrobenzoic Acid / metabolism; Endothelial Cells / enzymology; Endothelial Cells / metabolism; Glutathione / metabolism; Humans; NADH, NADPH Oxidoreductases / metabolism; Oxidation-Reduction; Thioctic Acid / analogs & derivatives; Thioctic Acid / analysis; Thioctic Acid / metabolism
Sources: Crossref, ORCID
Added: July 25, 2021

2006 chapter

DCLHb and rHb1.1

In Blood Substitutes (pp. 399–414).

By: D. Nelson*

Sources: Crossref, ORCID
Added: July 25, 2021

2006 conference paper

Stability of parenteral nutrition admixtures admixed with a novel parenteral iron dosage form

Presented at the National Meeting, Society for Free Radical Biology & Medicine, Denver, CO.

By: D. Nelson, D. Driscoll, A. Gupta, J. Joy, A. Silvestri & B. Bistrian

Event: National Meeting, Society for Free Radical Biology & Medicine at Denver, CO

Source: NC State University Libraries
Added: July 29, 2021

2005 report

Methods for the preparation and formulation of magnesium valproate hydrate

(U.S. Patent No. 7482486).

By: D. Nelson & N. Malkar

Source: NC State University Libraries
Added: July 29, 2021

2004 journal article

Effective attenuation of endotoxin-induced acute lung injury by 2,3-diacetyloxybenzoic acid in two independent animal models

Pulmonary Pharmacology & Therapeutics, 17(2), 105–110.

By: D. Eiznhamer, M. Flavin, G. Jesmok*, J. Borgia*, D. Nelson*, K. Burhop*, Z. Xu

co-author countries: United States of America 🇺🇸
author keywords: acute lung injury; acute respiratory distress syndrome; benzoic acids; endotoxin; microvascular permeability
MeSH headings : Acetates; Animals; Blood-Air Barrier / drug effects; Capillary Permeability / drug effects; Disease Models, Animal; Endotoxins; Guinea Pigs; Hydroxybenzoates / pharmacology; Lipopolysaccharides; Lung / blood supply; Neutrophils / pathology; Prodrugs / pharmacology; Respiratory Distress Syndrome / chemically induced; Respiratory Distress Syndrome / drug therapy; Sheep
Sources: Crossref, ORCID
Added: July 25, 2021

2004 report

Oligo(ethylene glycol)-terminated 1,2-dithiolanes and their conjugates useful for preparing self-assembled monolayers

(U.S. Patent No. 6756354).

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2004 conference paper

Oxygen Carriers as Alternatives to Red Blood Cell Transfusions

Nelson, D. J. (2004, May 1). Presented at the Annual Meeting, Infusion Nurses Society, Salt Lake City, UT.

By: D. Nelson

Event: Annual Meeting, Infusion Nurses Society at Salt Lake City, UT on May 1, 2004

Source: NC State University Libraries
Added: July 29, 2021

2003 report

Aminosalicylate derivatives for treatment of inflammatory bowel disease

(U.S. Patent No. 7157444).

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2003 report

Stable hydralazine pharmaceutical compositions

(U.S. Patent Application No. 7989452).

By: D. Nelson & D. Barbeau

Source: NC State University Libraries
Added: July 29, 2021

2002 chapter

Blood substitutes: Hemoglobin-based oxygen carriers

In J. Swarbrick & J. C. Boylan (Eds.), Encyclopedia of Pharmaceutical Technology (Vol. 20, pp. 236–262). New York: Marcel Dekker, Inc.

By: D. Nelson

Ed(s): J. Swarbrick & J. Boylan

Source: NC State University Libraries
Added: July 29, 2021

2001 report

Biocompatible surfaces and a method for their preparation

(U.S. Patent No. US6204254B1).

By: D. Nelson, T. Hai, D. Pereira & T. Estep

Source: NC State University Libraries
Added: July 29, 2021

2000 chapter

Blood substitutes: Hemoglobin-based oxygen carriers

In J. Swarbrick & J. C. Boylan (Eds.), Encyclopedia of Pharmaceutical Technology (Vol. 19, pp. 1–33). New York: Marcel Dekker, Inc.

By: D. Nelson

Ed(s): J. Swarbrick & J. Boylan

Source: NC State University Libraries
Added: July 29, 2021

2000 report

Reagents for isotropic size enhancement of a peptide, protein, nucleotide or other substrate

(U.S. Patent No. 6018035).

By: T. Hai, D. Pereira & D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

2000 journal article

Surface Modification of Diaspirin Cross-linked Hemoglobin (DCLHb) with Chondroitin-4-sulfate Derivatives. Part 1

Bioconjugate Chemistry, 11(5), 705–713.

By: T. Hai*, D. Pereira*, D. Nelson*, J. Catarello* & A. Srnak*

co-author countries: United States of America 🇺🇸
MeSH headings : Aspirin / analogs & derivatives; Aspirin / chemistry; Aspirin / pharmacology; Blood Substitutes / chemistry; Blood Substitutes / pharmacology; Carbohydrate Sequence; Chondroitin Sulfates / chemistry; Chondroitin Sulfates / pharmacology; Erythrocyte Aggregation / drug effects; Hemoglobins / chemistry; Hemoglobins / pharmacology; Humans; Molecular Sequence Data; Structure-Activity Relationship; Surface Properties
Sources: Crossref, ORCID
Added: July 25, 2021

1999 report

Covalently modified hemoglobin composition having low temperature-dependent oxygen-binding function

(U.S. Patent Application No. 6180598).

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

1999 journal article

Polymerization of Diaspirin Cross-Linked Hemoglobin (DCLHb) with Water-Soluble, Nonimmunogenic Polyamide Cross-Linking Agents

Bioconjugate Chemistry, 10(6), 1013–1020.

By: T. Hai*, D. Pereira*, D. Nelson*, A. Srnak* & J. Catarello*

co-author countries: United States of America 🇺🇸
MeSH headings : Aspirin / analogs & derivatives; Aspirin / chemistry; Aspirin / metabolism; Cross-Linking Reagents; Hemoglobins / chemistry; Hemoglobins / metabolism; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Molecular Weight; Nylons / chemistry; Oxygen / metabolism; Oxyhemoglobins / chemistry; Polymers / chemistry; Solubility; Water
Sources: Crossref, ORCID
Added: July 25, 2021

1999 journal article

Polymerization of diaspirin crosslinked hemoglobin (DCLHb) with PEG activated with benzenesulfonate bearing electron-withdrawing groups

Tetrahedron, 55(8), 2147–2156.

By: T. Hai*, D. Pereira*, D. Nelson* & A. Srnak*

co-author countries: United States of America 🇺🇸
author keywords: proteins; polymerisation
Sources: Crossref, ORCID
Added: July 25, 2021

1999 report

Therapeutic hemoglobin composition having isotropically increased size

(U.S. Patent No. 5981710).

By: T. Hai, D. Nelson, D. Pereira & T. Estep

Source: NC State University Libraries
Added: July 29, 2021

1998 chapter

*HemAssist™: Development and Clinical Profile

In A. S. Rudolph, R. Rabinovici, & G. Z. Feuerstein (Eds.), Red Blood Cell Substitutes (pp. 365–412).

By: D. Nelson

Ed(s): A. Rudolph, R. Rabinovici & G. Feuerstein

Sources: Crossref, ORCID
Added: July 28, 2021

1998 journal article

A Convenient Large Scale Synthesis of N, N'-Disuccinimidyl Carbonate

Synthetic Communications, 28(21), 4019–4024.

By: D. Pereira*, T. Hai* & D. Nelson*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: July 28, 2021

1998 journal article

Absence of Immunogenicity of Diaspirin Cross-Linked Hemoglobin in Humans

Blood, 91(2), 710–716.

By: M. Patel*, E. Webb*, T. Shelbourn*, C. Mattia-Goldberg*, A. George*, F. Zhang*, E. Moore*, D. Nelson*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
Sources: Crossref, ORCID
Added: July 25, 2021

1998 conference paper

Hemoglobin Therapeutics: Current status and clinical trials

Nelson, D. J. (1998, March 18). Presented at the Annual Meeting, Southeastern Area Blood Bankers, Atlanta, GA.

By: D. Nelson

Event: Annual Meeting, Southeastern Area Blood Bankers at Atlanta, GA on March 18-20, 1998

Source: NC State University Libraries
Added: July 29, 2021

1998 journal article

Synthesis of Water-Soluble, Nonimmunogenic Polyamide Cross-Linking Agents†

Bioconjugate Chemistry, 9(6), 645–654.

By: T. Hai*, D. Pereira* & D. Nelson*

co-author countries: United States of America 🇺🇸
MeSH headings : Chromatography, Gel; Cross-Linking Reagents / chemical synthesis; Detergents / chemistry; Hemoglobins / chemistry; Magnetic Resonance Spectroscopy; Nylons / chemistry; Protein Denaturation; Proteins / chemistry; Solubility; Terminology as Topic
Sources: Crossref, ORCID
Added: July 25, 2021

1997 chapter

Blood and HemAssist (DCLHb): Potentially a Complementary Therapeutic Team

In T. M. S. Chang (Ed.), Blood Substitutes: Principles, Methods, Products and Clinical Trials (pp. 36–91). New York: Karger Landes Systems.

By: D. Nelson

Ed(s): T. Chang

Source: NC State University Libraries
Added: July 29, 2021

1997 conference paper

DCLHb, a well-characterized hemoglobin

VII International Symposium on Blood Substitutes, Program and Abstracts, (P08-b), 101.

By: D. Nelson, M. Patel, T. Shelbourn, E. Webb, T. Lo-Tseng & E. Moore

Event: VII International Symposium on Blood Substitutes at Waseda University, Tokyo, Japan on September 7-10, 1997

Source: NC State University Libraries
Added: July 29, 2021

1997 journal article

Progress in developing therapeutic blood substitutes. Chicago Section of the American Chemical Society

Chemical Bulletin, 1–2.

By: D. Nelson

Source: NC State University Libraries
Added: July 29, 2021

1997 report

Stabilization of therapeutic hemoglobin compositions

(Patent No. WO1997039027A1).

By: T. Hai & D. Nelson

Source: NC State University Libraries
Added: July 27, 2021

1996 journal article

Cyclizations during the Grignard reactions of omega-bromoalkynes

Croatica Chimica Acta, 69(4), 1473–1490.

By: J. Crandall, W. Michaely, F. Collonges, T. Ayers, J. Gajewski & D. Nelson

Source: NC State University Libraries
Added: July 30, 2021

1996 conference paper

Diaspirin Crosslinked Hemoglobin (DCLHb): Biocompatibility Studies

Presented at the American Association of Pharmaceutical Scientists.

By: M. Patel, E. Webb, T. Shelbourn & D. Nelson

Event: American Association of Pharmaceutical Scientists

Source: NC State University Libraries
Added: July 27, 2021

1996 conference paper

Hemoglobin Based Blood Substitutes: New Biologics with Unique and Unexpected Pharmacologic Properties

Nelson, D. J. (1996, May 20). Presented at the American Association of Pharmaceutical Scientists Midwest Regional Meeting, Chicago, IL.

By: D. Nelson

Event: American Association of Pharmaceutical Scientists Midwest Regional Meeting at Chicago, IL on May 20, 1996

Source: NC State University Libraries
Added: July 30, 2021

1996 report

Method and composition for administration of beneficial agent by controlled dissolution

(U.S. Patent No. 5510115).

By: J. Breillatt, L. Woo, D. Nelson, R. Appl, N. Weinless, S. Pokropinski, P. Soltys, S. Barenburg

Source: NC State University Libraries
Added: July 30, 2021

1996 journal article

Modification of DCLHb with proprietary polyamides

Artif Cells Blood Subs Immob Biotech, 24(4), 347.

By: T. Hai, D. Pereira, A. Srnak & D. Nelson

Source: NC State University Libraries
Added: July 30, 2021

1996 report

Use of 2,3-alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome

(U.S. Patent No. 5502111).

By: M. Flavin, D. Nelson, J. Borgia & G. Jesmok

Source: NC State University Libraries
Added: July 30, 2021

1995 conference paper

Hemoglobin Based Blood Substitutes

Presented at the Annual Meeting of the Oxygen Society.

By: D. Nelson

Event: Annual Meeting of the Oxygen Society

Source: NC State University Libraries
Added: July 30, 2021

1994 journal article

Diaspirin Crosslinked Hemoglobin (DCLHbTM): Bioanalytical Studies in Swine

Artificial Cells, Blood Substitutes, and Biotechnology, 22(3), 917–922.

By: S. Bush*, T. Marshall*, J. Spicuzza* & D. Nelson*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Aspirin / administration & dosage; Aspirin / analogs & derivatives; Aspirin / pharmacokinetics; Aspirin / toxicity; Blood Substitutes / administration & dosage; Blood Substitutes / pharmacokinetics; Blood Substitutes / toxicity; Hemoglobins / administration & dosage; Hemoglobins / pharmacokinetics; Hemoglobins / toxicity; Infusions, Intravenous; Iron / blood; Iron / metabolism; Kidney / metabolism; Liver / metabolism; Methemoglobinemia / etiology; Oxygen / blood; Oxygen / metabolism; Swine
Source: Crossref
Added: July 28, 2021

1994 journal article

Diaspirin Crosslinked Hemoglobin (DCLHbTM)Polymerization

Artificial Cells, Blood Substitutes, and Biotechnology, 22(3), 923–931.

By: T. Hai*, D. Nelson*, D. Pereira* & A. Srnak*

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acids, Diamino; Aspirin / analogs & derivatives; Aspirin / chemistry; Aspirin / isolation & purification; Aspirin / metabolism; Binding Sites; Blood Substitutes / chemistry; Blood Substitutes / isolation & purification; Blood Substitutes / metabolism; Cyanobacteria Toxins; Hemoglobins / chemistry; Hemoglobins / isolation & purification; Hemoglobins / metabolism; Humans; In Vitro Techniques; Indicators and Reagents; Oxygen / metabolism; Polyethylene Glycols; Polymers / chemistry; Polymers / isolation & purification
Source: Crossref
Added: July 28, 2021

1994 report

Water-soluble nonimmunogenic polyamide crosslinking agents

(Patent No. WO1994012220A2).

By: T. Hai & D. Nelson

Source: NC State University Libraries
Added: May 14, 2022

1993 conference paper

Diaspirin Crosslinked Hemoglobin (DCLHbTM) Polymerization

Vth International Symposium on Blood Substitutes, Program and Abstracts, (H66).

By: T. Hai, D. Nelson, D. Pereira & A. Srnak

Event: Vth International Symposium on Blood Substitutes at San Diego, CA on March 17-20, 1993

Source: NC State University Libraries
Added: July 30, 2021

1993 conference paper

Diaspirin Crosslinked Hemoglobin (DCLHb): Bioanalytical Studies in Swine

Vth International Symposium on Blood Substitutes, Program and Abstracts, (H36).

By: S. Bush, T. Marshall, J. Spicuzza & D. Nelson

Event: Vth International Symposium on Blood Substitutes at San Diego, CA on March 17-20, 1993

Source: NC State University Libraries
Added: July 30, 2021

1993 report

Glassy sugar matrix for administration of beneficial agent in blood preservation and drug delivery

(Patent No. EP0343239B1).

By: J. Breillatt, L. Woo, D. Nelson & R. Appl

Source: NC State University Libraries
Added: May 14, 2022

1993 conference paper

Interactions of Human Monocytes with Hemoglobins: In Vitro Assessment

Vth International Symposium on Blood Substitutes, Program and Abstracts, (H37).

By: D. Nelson, N. Mozier & K. Gard

Event: Vth International Symposium on Blood Substitutes at San Diego, CA on March 17-20, 1993

Source: NC State University Libraries
Added: July 30, 2021

1993 report

Oxirane-modified hemoglobin based composition

(U.S. Patent No. US5248766A).

By: D. Nelson, T. Hai & A. Srnak

Source: NC State University Libraries
Added: July 30, 2021

1992 conference paper

Diaspirin cross-linked hemoglobin: an investigational drug exemplifying hemoglobin-based blood substitutes

Nelson, D. J., Bush, S. L., Farmer, M. C., & Picken, J. (1992, December). Presented at the American Society of Hospital Pharmacists National Meeting, Orlando, FL.

By: D. Nelson, S. Bush, M. Farmer & J. Picken

Event: American Society of Hospital Pharmacists National Meeting at Orlando, FL

Source: NC State University Libraries
Added: July 30, 2021

1992 conference paper

New blood product: diaspirin cross-linked hemoglobin as a blood substitute, I: Characterization and oxygen transport.

Transfusion, 32(S8), S21.

By: D. Nelson, S. Bush, T. Marshall & J. Spicuzza

Event: American Association of Blood Banks National Meeting at San Francisco, CA

Source: NC State University Libraries
Added: July 30, 2021

1992 conference paper

New blood product: diaspirin cross-linked hemoglobin as a blood substitute, II: Storage stability

Transfusion, 32(8S), S22.

By: S. Bush, D. Nelson & T. Shelbourn

Event: American Association of Blood Banks National Meeting at San Francisco, CA

Source: NC State University Libraries
Added: July 30, 2021

1992 report

Non-immunogenic hemoglobin oligomer composition used as oxygen carrier, maintains normal oxygen tension in organs and tissues, is non-toxic or pyrogenic and free from contamination

(U.S. Patent Application No. WO9203-155-A).

By: D. Nelson & T. Hai

Source: NC State University Libraries
Added: July 30, 2021

1992 journal article

Preparation and Characterization of Diaspirin Cross-Linked Hemoglobin Solutions for Preclinical Studies

Biomaterials, Artificial Cells and Immobilization Biotechnology, 20(2-4), 423–427.

By: D. Nelson*, M. Azari*, R. Brown*, K. Burhop*, S. Bush*, J. Catarello*, H. Chuang*, C. Downing* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Aspirin / analogs & derivatives; Blood Substitutes / isolation & purification; Cross-Linking Reagents; Drug Evaluation, Preclinical; Drug Stability; Hemoglobins / isolation & purification; Humans; Solutions
Source: Crossref
Added: July 28, 2021

1992 report

Process for the Production of Crosslinked Hemoglobin in the Presence of Sodium Tripolyphosphate

(U.S. Patent No. 5128452).

By: T. Hai & D. Nelson

Source: NC State University Libraries
Added: July 30, 2021

1992 journal article

Synthesis and Properties of Polymerized, Diaspirin Cross-Linked Hemoglobins

Biomaterials, Artificial Cells and Immobilization Biotechnology, 20(2-4), 253–258.

By: D. Nelson*, T. Hai*, A. Smak*, A. Ebeling*, G. Kunas*, J. Catarello*, K. Burhop*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Aspirin / analogs & derivatives; Blood Substitutes / chemical synthesis; Blood Substitutes / therapeutic use; Blood Substitutes / toxicity; Chlorocebus aethiops; Cross-Linking Reagents; Drug Evaluation, Preclinical; Female; Glutaral; Hemoglobins / chemical synthesis; Hemoglobins / therapeutic use; Hemoglobins / toxicity; Male; Rats; Rats, Sprague-Dawley; Shock / therapy; Swine
Source: Crossref
Added: July 28, 2021

1991 conference paper

Diaspirin Crosslinked Hemoglobin (DCLHb): An Update

Presented at the Annual Scientific Meeting IX, British Blood Transfusion Society, Nottingham, England.

By: D. Nelson

Event: Annual Scientific Meeting IX, British Blood Transfusion Society at Nottingham, England on September 3-6, 1991

Source: NC State University Libraries
Added: July 30, 2021

1991 conference paper

Immunological Implications of Protein Formulations

Presented at the American Association of Pharmaceutical Sciences Eastern Regional Meeting, New Brunswick, NJ.

By: D. Nelson

Event: American Association of Pharmaceutical Sciences Eastern Regional Meeting at New Brunswick, NJ on June 6-7, 1991

Source: NC State University Libraries
Added: July 30, 2021

1991 report

Pharmaceutical Grade 3,5-Dibromosalicylic Acid

(U.S. Patent No. 5013866).

By: T. Hai & D. Nelson

Source: NC State University Libraries
Added: July 30, 2021

1991 journal article

Preparation and characterization of diaspirin cross-linked hemoglobin solutions for preclinical studies

Biomaterials, Artificial Cells and Immobilization Biotechnology, 19(2), 452.

By: D. Nelson, M. Azari, C. Baron, S. Bush, J. Catarello, T. Marshall, J. Spicuzza, P. Zieske

Source: NC State University Libraries
Added: July 30, 2021

1991 report

Preparation of Bis(Salicyl) Diesters

(U.S. Patent No. 5041615).

By: T. Hai, D. Nelson & A. Srnak

Source: NC State University Libraries
Added: July 30, 2021

1991 journal article

Synthesis and properties of polymerized, diaspirin cross-linked hemoglobins

Biomaterials, Artificial Cells and Immobilization Biotechnology, 19(2), 451.

By: D. Nelson, T. Hai & A. Srnak

Source: NC State University Libraries
Added: July 30, 2021

1990 conference paper

Analytical Characterization of alpha,alpha-Crosslinked Hemoglobin

Presented at the 23rd Great Lakes Regional Meeting, American Chemical Society, DeKalb, IL.

By: R. Kandler, S. Bush, J. Spicuzza, K. Bosman, T. Marshall, C. Baron, P. Zieske, D. Nelson

Event: 23rd Great Lakes Regional Meeting, American Chemical Society at DeKalb, IL on May 30 - June 1, 1990

Source: NC State University Libraries
Added: July 30, 2021

1990 conference paper

Determination of the Percent cross-linking in Diaspirin Cross-lined Hemoglobin (DCLHb) using Size-exclusion Chromatography

Presented at the Annual Meeting, American Institute of Chemical Engineers, Chicago, IL.

By: C. Baron, S. Bush & D. Nelson

Event: Annual Meeting, American Institute of Chemical Engineers at Chicago, IL on November 11-16, 1990

Source: NC State University Libraries
Added: July 30, 2021

1990 conference paper

Diaspirin Crosslinked Hemoglobin (DCLHb): Preparation and Properties

Presented at the 23rd Great Lakes Regional Meeting, American Chemical Society, DeKalb, IL.

By: D. Nelson, T. Estep, T. Hai, E. Bobka & S. Bush

Event: 23rd Great Lakes Regional Meeting, American Chemical Society at DeKalb, IL on May 30 - June 1, 1990

Source: NC State University Libraries
Added: July 30, 2021

1990 conference paper

Directing Intramolecular Crosslinking of Hemoglobin

Presented at the 23rd Great Lakes Regional Meeting, American Chemical Society, DeKalb, IL.

By: T. Hai, D. Nelson & A. Srnak

Event: 23rd Great Lakes Regional Meeting, American Chemical Society at DeKalb, IL on May 30 - June 1, 1990

Source: NC State University Libraries
Added: July 30, 2021

1989 journal article

Novel aspects of diaspirin cross-linked hemoglobin synthesis and purification

Biomaterials, Artificial Cells and Artificial Organs, 17(5), 636.

By: T. Estep, E. Bobka, A. Ebeling, T. Hai, D. Nelson, R. Pankau, A. Srnak

Source: NC State University Libraries
Added: July 30, 2021

1989 conference paper

The Use of 31P NMR in Determining the Enan¬tiomeric Purity of Lactic and Malic Acid Samples

Smith, W. J., Flavin, M., Nelson, D., Pereira, D., & Ziemnicka-Merchant, B. (1989, May 11). Presented at the Baxter Healthcare Corporation Parenterals R & D Symposium.

By: W. Smith, M. Flavin, D. Nelson, D. Pereira & B. Ziemnicka-Merchant

Event: Baxter Healthcare Corporation Parenterals R & D Symposium on May 11, 1989

Source: NC State University Libraries
Added: August 3, 2021

1988 conference paper

Cardiovascular Maintenance with Blood Substitutes

Presented at the Baxter Travenol Science and Technology Seminar, Laguna Niguel, CA.

By: K. Burhop & D. Nelson

Event: Baxter Travenol Science and Technology Seminar at Laguna Niguel, CA on July 19-22, 1988

Source: NC State University Libraries
Added: July 30, 2021

1987 report

Nutrient Monoesters

(U.S. Patents No. 4655057).

By: D. Nelson & B. Rowe

Source: NC State University Libraries
Added: July 30, 2021

1987 report

Nutrient Polyesters

(U.S. Patent No. 4701443).

By: D. Nelson & B. Rowe

Source: NC State University Libraries
Added: July 30, 2021

1985 journal article

The Reaction of D-Glucose With Substituted Anilines: Investigation by Carbon-13 NMR Spectroscopy

Journal of Carbohydrate Chemistry, 4(1), 91–97.

By: D. Nelson* & M. Lavin

Sources: Crossref, ORCID
Added: July 25, 2021

1984 journal article

Maillard polymers derived from D-glucose, D-fructose, 5-(hydroxymethyl)-2-furaldehyde and glycine and methionine

Journal of Agricultural and Food Chemistry, 32(6), 1428–1432.

By: M. Feather & D. Nelson*

Sources: Crossref, ORCID
Added: July 28, 2021

1979 journal article

CIDNP/FTNMR as a mechanistic probe in the pulse radiolysis of aqueous acetone and acetaldehyde

The Journal of Physical Chemistry, 83(17), 2186–2195.

By: D. Nelson*

Sources: Crossref, ORCID
Added: July 28, 2021

1979 journal article

Carbon-13 CIDNP from reactions of some simple organic and inorganic radicals during pulse radiolysis

The Journal of Physical Chemistry, 83(26), 3444–3448.

By: R. Lawler, D. Nelson* & A. Trifunac

Sources: Crossref, ORCID
Added: July 25, 2021

1979 journal article

Chemically induced magnetic polarization studies in radiation and photochemistry

Reviews of Chemical Intermediates, 3(1-2), 131–168.

By: D. Nelson*, A. Trifunac*, M. Thurnauer* & J. Norris*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: July 25, 2021

1979 journal article

Synthesis of aryl alkynes

Preprints, American Chemical Society Division of Petroleum Chemistry, 24(1), 240–242.

By: D. Nelson

Source: NC State University Libraries
Added: August 3, 2021

1978 journal article

CIDNP in pulse radiolysis of aqueous dimethyl sulfoxide

The Journal of Physical Chemistry, 82(12), 1400–1403.

By: D. Nelson*

Sources: Crossref, ORCID
Added: July 25, 2021

1978 journal article

CIDNP in the radiolysis of aqueous methanol indication of methoxy radical involvement

Chemical Physics Letters, 55(2), 323–326.

By: D. Nelson*, C. Mottley* & A. Trifunac*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: July 25, 2021

1978 journal article

Chemically induced dynamic electron polarization. Examples; of S-T±1 polarization

[Report]. Journal of Magnetic Resonance (1969), 30(2), 263–272.

By: A. Trifunac, D. Nelson* & C. Mottley

Sources: Crossref, ORCID, NC State University Libraries
Added: July 25, 2021

1978 journal article

Time-resolved electron paramagnetic resonance and flow-Fourier transform nuclear magnetic resonance study in radiation chemistry. An example of Overhauser CIDNP

Journal of the American Chemical Society, 100(16), 5244–5246.

By: A. Trifunac & D. Nelson*

Sources: Crossref, ORCID
Added: July 25, 2021

1978 journal article

Unstable intermediates. Part 179. Electron spin resonance studies of radicals formed in irradiated organic sulphides and disulphides

Journal of the Chemical Society, Perkin Transactions 2, (3), 225.

By: R. Petersen, D. Nelson* & M. Symons

Sources: Crossref, ORCID
Added: July 28, 2021

1977 conference paper

Chemically Induced Dynamic Electron Polarization (CIDEP) in Pulse Radiolysis Examples of S-T-1 Polarization

Presented at the 174th National Meeting of the American Chemical Society, Division of Physical Chemistry, Chicago, Illinois.

By: A. Trifunac & D. Nelson

Event: 174th National Meeting of the American Chemical Society, Division of Physical Chemistry at Chicago, Illinois on August 28 - September 2, 1977

Source: NC State University Libraries
Added: August 3, 2021

1977 conference paper

Chemically Induced Dynamic Nuclear Polarization in Pulse Radiolysis of Aqueous Solutions

Presented at the 174th National Meeting, The American Chemical Society, Division of Organic Chemistry, Chicago, Illinois.

By: A. Trifunac & D. Nelson

Event: 174th National Meeting, The American Chemical Society, Division of Organic Chemistry at Chicago, Illinois on August 28 - September 2, 1977

Source: NC State University Libraries
Added: August 3, 2021

1977 journal article

Chemically induced dynamic electron polarization in pulse radiolysis. S-T.+-.1 polarization from hydrogen radical reactions

Journal of the American Chemical Society, 99(1), 289–290.

By: A. Trifunac & D. Nelson*

Sources: Crossref, ORCID
Added: July 25, 2021

1977 journal article

Chemically induced dynamic electron polarization. Pulse radiolysis of aqueous solutions of micelles

Chemical Physics Letters, 46(2), 346–348.

By: A. Trifunac* & D. Nelson*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: July 25, 2021

1977 journal article

Electron addition to organic halides: an ESR study of PhC2I−

Chemical Physics Letters, 47(3), 436–439.

By: D. Nelson* & M. Symons

Sources: Crossref, ORCID
Added: July 25, 2021

1977 journal article

Modification of the Grignard reaction

Journal of Chemical Education, 54(10), 648.

By: D. Nelson*, R. DiFrancesco & D. Petters

Sources: Crossref, ORCID
Added: July 25, 2021

1977 journal article

Nuclear magnetic resonance in pulse radiolysis. 2. CIDNP in radiolysis of aqueous solutions

Journal of the American Chemical Society, 99(6), 1745–1752.

By: A. Trifunac & D. Nelson*

Sources: Crossref, ORCID
Added: July 28, 2021

1977 journal article

Synthesis of aryl alkynes. 1. 2-Ethyl-4-methoxyphenylacetylene

The Journal of Organic Chemistry, 42(20), 3308–3309.

By: D. Nelson* & E. Uschak

Sources: Crossref, ORCID
Added: July 28, 2021

1977 journal article

Unstable intermediates. Part 169. Electron capture processes in organic phosphates: an electron spin resonance study

Journal of the Chemical Society, Perkin Transactions 2, (3), 286.

By: D. Nelson* & M. Symons

Sources: Crossref, Web Of Science, ORCID
Added: July 25, 2021

1977 journal article

Unstable intermediates. Part 178. The structure of intermediates formed in the radiolysis of thiols

Journal of the Chemical Society, Perkin Transactions 2, (15), 2005.

By: D. Nelson*, R. Petersen & M. Symons

Sources: Crossref, ORCID
Added: July 28, 2021

1976 conference paper

An ESR Study of Radiation Damage in Organophosphates

Presented at the 8th Central Regional Meeting,The American Chemical Society, Division of Organic Chemistry.

By: M. Symons & D. Nelson

Event: 8th Central Regional Meeting,The American Chemical Society, Division of Organic Chemistry

Source: NC State University Libraries
Added: August 3, 2021

1975 conference paper

Electron Capture by Phosphate Esters

Presented at the The Chemical Society, Spring Meeting.

By: M. Symons & D. Nelson

Event: The Chemical Society, Spring Meeting

Source: NC State University Libraries
Added: July 30, 2021

1975 journal article

Electron capture by pyrophosphate ions: an electron spin resonance study

International Journal for Radiation Physics and Chemistry, 7(4), 581–583.

By: S. Mishra*, D. Nelson* & M. Symons*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: July 28, 2021

1975 journal article

On the conformation of β-bromo radicals

Tetrahedron Letters, 16(34), 2953–2954.

By: D. Nelson* & M. Symons*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: July 25, 2021

1975 journal article

The detection of thiyl radicals by ESR spectroscopy

Chemical Physics Letters, 36(3), 340–341.

By: D. Nelson* & M. Symons*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Sources: Crossref, ORCID
Added: July 28, 2021

1975 journal article

Unstable intermediates. Part CLIII. Electron spin resonance spectra and structure of dichlorophosphoranyl radicals

Journal of the Chemical Society, Dalton Transactions, (12), 1164.

By: D. Nelson* & M. Symons

Sources: Crossref, ORCID
Added: July 25, 2021

1973 journal article

A new synthesis of allene alcohols

Journal of the Chemical Society, Chemical Communications, 444.

By: D. Nelson

Source: NC State University Libraries
Added: July 30, 2021

1973 journal article

Synthesis of a 5,6-dienol

Journal of the Chemical Society, Chemical Communications, (13), 444a.

By: D. Nelson* & W. Miller

Sources: Crossref, ORCID
Added: July 25, 2021

1970 conference paper

Synthetic Route to Polycyclic Conjugated Systems Containing Fused Four-Membered Rings

Presented at the 159th National Meeting, The American Chemical Society, Division of Organic Chemistry.

By: D. Nelson

Event: 159th National Meeting, The American Chemical Society, Division of Organic Chemistry

Source: NC State University Libraries
Added: July 30, 2021

1969 journal article

Chemistry of sulfoacetic acid derivatives. II. Reactions of phenyl esters and anilides of sulfoacetic acid

The Journal of Organic Chemistry, 34(11), 3414–3420.

By: B. Hoogenboom, M. El-Faghi, S. Fink, E. Hoganson, S. Lindberg, T. Lindell, C. Linn, D. Nelson ...

Sources: Crossref, ORCID
Added: July 28, 2021

1969 journal article

Cyclization of acetylenic alkyl radicals

Tetrahedron Letters, 10(21), 1653–1656.

By: J. Crandall* & D. Keyton*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: July 28, 2021

1969 conference paper

Organolithium Cyclizations of Acetylene Derivatives

Crandall, J. K., & Nelson, D. J. (1969, January). Presented at the 158th National Meeting, The American Chemical Society, Division of Organic Chemistry.

By: J. Crandall & D. Nelson

Event: 158th National Meeting, The American Chemical Society, Division of Organic Chemistry

Source: NC State University Libraries
Added: July 30, 2021

1969 conference paper

The Chemistry of Sulfoacetic Acid Derivatives

Presented at the 156th National Meeting, The American Chemical Society.

By: B. Hoogenboom & D. Nelson

Event: 156th National Meeting, The American Chemical Society

Source: NC State University Libraries
Added: July 30, 2021

1969 journal article

The reaction of arynes with enamines: A new ring expansion leading to benzocycloheptenone

Tetrahedron Letters, 10(47), 4163–4168.

By: D. Keyton*, G. Griffin*, M. Kuehne* & C. Bayha*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: July 28, 2021

1968 journal article

Allenes by lithium aluminum hydride reduction of propargyl derivatives

The Journal of Organic Chemistry, 33(9), 3655–3657.

By: J. Crandall, D. Keyton & J. Kohne

Sources: Crossref, ORCID
Added: July 28, 2021

1968 journal article

An intramolecular alkylation route to cycloalkylacetylenes

Chemical Communications (London), (18), 1069.

By: J. Crandall & D. Keyton

Sources: Crossref, ORCID
Added: July 28, 2021

1968 thesis

Organometallic cyclization of acetylene derivatives

(Ph.D. Dissertation). Indiana University.

By: D. Nelson

Source: NC State University Libraries
Added: August 3, 2021

conference paper

DCLHb, a hemoglobin-based oxygen carrier: manufacture and characterization for use in clinical studies

Nelson, D. J., Azari, M., Moore, E., Estep, T., Picken, J., & Rohn, K. VII International Symposium on Blood Substitutes, Program and Abstracts, (3B-04), 34.

By: D. Nelson, M. Azari, E. Moore, T. Estep, J. Picken & K. Rohn

Event: VII International Symposium on Blood Substitutes at Waseda University, Tokyo, Japan on September 7-10, 1997

Source: NC State University Libraries
Added: July 29, 2021

conference paper

Evaluation of the immunogenicity of diaspirin crosslinked hemoglobin (DCLHb)

Nelson, D., Webb, E., Shelbourn, T., Moore, E., Mattia-Goldberg, C., & Patel, M. VII International Symposium on Blood Substitutes, Program and Abstracts, (P09-b), 102.

By: D. Nelson, E. Webb, T. Shelbourn, E. Moore, C. Mattia-Goldberg & M. Patel

Event: VII International Symposium on Blood Substitutes at Waseda University, Tokyo, Japan on September 7-10, 1997

Source: NC State University Libraries
Added: July 29, 2021

conference paper

Moisture Analysis in Pharmaceutical Products

Ryan, J. A., & Nelson, D. Presented at the Labcon Central, Rosemont, IL.

By: J. Ryan & D. Nelson

Event: Labcon Central at Rosemont, IL on September 20-22, 1983

Source: NC State University Libraries
Added: August 3, 2021

conference paper

New Light on an old Reaction: An NMR Study of Glucose-Amine Adducts

Ryan, J. A., Lavin, M., & Nelson, D. J. 327.

By: J. Ryan, M. Lavin & D. Nelson

Event: Labcon at Rosemont, IL on September 28-30, 1982

Source: NC State University Libraries
Added: August 3, 2021

manuscript

Physiological Calcium Phosphate Management in Two Biofluids

Deanna Nelson

Source: ORCID
Added: February 1, 2024

conference paper

Synthesis of Aryl Alkynes

Nelson, D. J. Presented at the Symposium on Synthesis and Reactions of Acetylenes, Division of Petroleum Chemistry, Inc., National Meeting of the American Chemical Society, Honolulu, Hawaii.

By: D. Nelson

Event: Symposium on Synthesis and Reactions of Acetylenes, Division of Petroleum Chemistry, Inc., National Meeting of the American Chemical Society at Honolulu, Hawaii on April 1-6, 1979

Source: NC State University Libraries
Added: August 3, 2021

conference paper

Variable Field CIDNP in Pulse Radiolysis

Nelson, D. J. Presented at the Conference on Chemically Induced Magnetic Polarization, Queen's University, Kingston, Ontario.

By: D. Nelson

Event: Conference on Chemically Induced Magnetic Polarization at Queen's University, Kingston, Ontario on June 7-11, 1978

Source: NC State University Libraries
Added: August 3, 2021

conference paper

Variable Field CIDNP/Flow FTNMR in the Study of Pulse Radiolysis

Nelson, D. J. Presented at the Division of Physical Chemistry, National Meeting of the American Chemical Society, Honolulu, Hawaii.

By: D. Nelson

Event: Division of Physical Chemistry, National Meeting of the American Chemical Society at Honolulu, Hawaii on April 1-6, 1979

Source: NC State University Libraries
Added: August 3, 2021

Education

Updated: November 30th, 2016 09:55

1964 - 1968

Indiana University Bloomington Bloomington, IN, US
Ph.D.

1960 - 1964

Gustavus Adolphus College Saint Peter, MN, US
B.S. Chemistry/Mathematics

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.