David Lawrence Aylor

Phenotype variability in diet-induced obesity and response to (−)-epigallocatechin gallate supplementation in a Diversity Outbred mouse cohort: A model for exploring gene x diet interactions for dietary bioactives

Nutrition Research, 133, 78–93.

A cross-species approach using an in vivo evaluation platform in mice demonstrates that sequence variation in human RABEP2 modulates ischemic stroke outcomes

AMERICAN JOURNAL OF HUMAN GENETICS, 109(10), 1814–1827.

Impacts of Gestational FireMaster 550 Exposure on the Neonatal Cortex Are Sex Specific and Largely Attributable to the Organophosphate Esters

Neuroendocrinology, 113(12), 1262–1282.

A Neuroprotective Locus Modulates Ischemic Stroke Infarction Independent of Collateral Vessel Anatomy

FRONTIERS IN NEUROSCIENCE, 15.

A neuroprotective locus modulates ischemic stroke infarction independent of collateral vessel anatomy

Lee, H. K., Wetzel-Strong, S. E., Aylor, D. L., & Marchuk, D. A. (2020, December 4).

Age and Genetic Background Modify Hybrid Male Sterility in House Mice

GENETICS, 216(2), 585–597.

Age and genetic background modify hybrid male sterility in house mice

Widmayer, S. J., Handel, M. A., & Aylor, D. L. (2020, June 26).

Derivation of stable embryonic stem cell-like, but transcriptionally heterogenous, induced pluripotent stem cells from non-permissive mouse strains

MAMMALIAN GENOME, 31(9-12), 263–286.

Identification of novel neuroprotective loci modulating ischemic stroke volume in a cross between wild-derived inbred mouse strains

Lee, H. K., Widmayer, S. J., Huang, M.-N., Aylor, D. L., & Marchuk, D. A. (2019, March 28). (Vol. 3). Vol. 3.

Novel Neuroprotective Loci Modulating Ischemic Stroke Volume in Wild-Derived Inbred Mouse Strains

GENETICS, 213(3), 1079–1092.

Age and genetic background determine hybrid male sterility in house mice

Widmayer, S. J., & Aylor, D. L. (2018, August 1). (Vol. 8). Vol. 8.

Animal models of endocrine disruption

Best Practice & Research Clinical Endocrinology & Metabolism, 32(3), 283–297.

Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus muscuius

SCIENTIFIC REPORTS, 8.

Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse

MAMMALIAN GENOME, 29(1-2), 168–181.

The NIEHS TaRGET II Consortium and environmental epigenomics

Nature Biotechnology, 36(3), 225–227.

The NIEHS TaRGET II Consortium and environmental epigenomics

Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism

TOXICOLOGICAL SCIENCES, 158(1), 48–62.

Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross

GENETICS, 206(2), 557–572.

Genetic Background, Maternal Age, and Interaction Effects Mediate Rates of Crossing Over in Drosophila melanogaster Females

G3-GENES GENOMES GENETICS, 6(5), 1409–1416.

A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2

PLOS GENETICS, 11(2).

Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance

Nature Genetics, 47(4), 353–360.

Erratum: Corrigendum: Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance

Nature Genetics, 47(6), 690–690.

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross

PLOS Genetics, 11(10), e1005504.

Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study

TOXICOLOGICAL SCIENCES, 148(2), 341–354.

The Founder Strains of the Collaborative Cross Express a Complex Combination of Advantageous and Deleterious Traits for Male Reproduction

G3-GENES GENOMES GENETICS, 5(12), 2671–2683.

Genetic Regulation of Zfp30, CXCL1, and Neutrophilic Inflammation in Murine Lung

GENETICS, 198(2), 735–U376.

Integrative Genetic Analysis of Allergic Inflammation in the Murine Lung

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 51(3), 436–445.

Genetically Determined Severity of Anti-Myeloperoxidase Glomerulonephritis

The American Journal of Pathology, 182(4), 1219–1226.

Modeling Host Genetic Regulation of Influenza Pathogenesis in the Collaborative Cross

PLoS Pathogens, 9(2), e1003196.

Using the emerging Collaborative Cross to probe the immune system

Genes & Immunity, 15(1), 38–46.

Expression Quantitative Trait Loci for Extreme Host Response to Influenza A in Pre-Collaborative Cross Mice

G3 Genes|Genomes|Genetics, 2(2), 213–221.

Genetic Analysis of Hematological Parameters in Incipient Lines of the Collaborative Cross

G3 Genes|Genomes|Genetics, 2(2), 157–165.

Architecture of energy balance traits in emerging lines of the Collaborative Cross

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 300(6), E1124–E1134.

Genetic analysis of complex traits in the emerging Collaborative Cross

Genome Research, 21(8), 1213–1222.

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal

Genes & Development, 23(21), 2521–2536.

From classical genetics to quantitative genetics to systems biology: Modeling epistasis

PLoS Genetics, 4(3).

eQTL Viewer: visualizing how sequence variation affects genome-wide transcription

BMC Bioinformatics, 8(7).

SNAP: Combine and Map modules for multilocus population genetic analysis

Bioinformatics, 22(11), 1399–1401.