David Michael Reif
predictive toxicology, data science, environmental health science, genetics, bioinformatics, NAMs, risk assessment, Artificial Intelligence / Machine Learning (AI / ML)
Works (171)
2025 article
Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes
Sakamuru, S., Travers, J., Klumpp-Thomas, C., Huang, R., Witt, K. L., Ferguson, S. S., … Xia, M. (2025, May 22). International Journal of Molecular Sciences.
open access via www.mdpi.com (publisher PDF)2025 article
Updated Guidance for Communicating PFAS Identification Confidence with Ion Mobility Spectrometry
Boatman, A. K., Chappel, J. R., Kirkwood-Donelson, K. I., Fleming, J. F., Reif, D. M., Schymanski, E. L., … Baker, E. S. (2025, January 28). BioRxiv (Cold Spring Harbor Laboratory).
2024 article
An in vitro and machine learning framework for quantifying serum albumin binding of per- and polyfluoroalkyl substances
Starnes, H. M., Green, A. J., Reif, D. M., & Belcher, S. M. (2024, September 19). Toxicological Sciences, Vol. 10.
2024 article
Deep autoencoder-based behavioral pattern recognition outperforms standard statistical methods in high-dimensional zebrafish studies
Green, A. J., Truong, L., Thunga, P., Leong, C., Hancock, M., Tanguay, R. L., & Reif, D. M. (2024, September 10). (S. V. Scarpino, Ed.). PLoS Computational Biology, Vol. 20.
Ed(s): S. Scarpino
2024 article
Investigating mouse hepatic lipidome dysregulation following exposure to emerging per- and polyfluoroalkyl substances (PFAS)
Kirkwood-Donelson, K. I., Chappel, J., Tobin, E., Dodds, J. N., Reif, D. M., DeWitt, J. C., & Baker, E. S. (2024, March 8). Chemosphere.
2024 article
Streamlining Phenotype Classification and Highlighting Feature Candidates: A Screening Method for Non-Targeted Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS) Data
Chappel, J. R., Kirkwood-Donelson, K. I., Dodds, J. N., Fleming, J., Reif, D. M., & Baker, E. S. (2024, September 18). Analytical Chemistry, Vol. 9.
2024 article
The GeoTox Package: Open-source software for connecting spatiotemporal exposure to individual and population-level risk
Messier, K. P., Reif, D. M., & Marvel, S. W. (2024, September 24). BioRxiv (Cold Spring Harbor Laboratory).
2023 article
Aggregated Molecular Phenotype Scores: Enhancing Assessment and Visualization of Mass Spectrometry Imaging Data for Tissue-Based Diagnostics
Chappel, J. R., King, M. E., Fleming, J., Eberlin, L. S., Reif, D. M., & Baker, E. S. (2023, August 14). Analytical Chemistry, Vol. 8.
2023 article
Bayesian matrix completion for hypothesis testing
Jin, B., Dunson, D. B., Rager, J. E., Reif, D. M., Engel, S. M., & Herring, A. H. (2023, March 15). Journal of the Royal Statistical Society Series C (Applied Statistics), Vol. 3.
2023 article
Deep autoencoder-based behavioral pattern recognition outperforms standard statistical methods in high-dimensional zebrafish studies
Green, A. J., Truong, L., Thunga, P., Leong, C., Hancock, M., Tanguay, R. L., & Reif, D. M. (2023, September 17).
2023 article
Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community
Wallis, D. J., Kotlarz, N., Knappe, D. R. U., Collier, D. N., Lea, C. S., Reif, D., … Hoppin, J. A. (2023, October 6). Environmental Science & Technology, Vol. 57, pp. 15348–15355.
2023 article
From big data to big insights: statistical and bioinformatic approaches for exploring the lipidome
Chappel, J. R., Kirkwood-Donelson, K. I., Reif, D. M., & Baker, E. S. (2023, October 25). Analytical and Bioanalytical Chemistry, Vol. 10.
2023 article
Guided optimization of ToxPi model weights using a Semi-Automated approach
Fleming, J. F., House, J. S., Chappel, J. R., Motsinger-Reif, A. A., & Reif, D. M. (2023, December 9). Computational Toxicology, Vol. 29.
2023 article
Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst
Phelps, D. W., Palekar, A. I., Conley, H. E., Ferrero, G., Driggers, J. H., Linder, K. E., … Yoder, J. A. (2023, February 14). Journal of Immunotoxicology, Vol. 20.
2023 article
MKX-AS1 Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients
Gonzalez, R. D., Small, G. W., Green, A. J., Akhtari, F. S., Motsinger-Reif, A. A., Quintanilha, J. C. F., … Wiltshire, T. (2023, May 17). Pharmaceuticals, Vol. 16.
2023 article
Pharmacogenomic Analyses Implicate B Cell Developmental Status and MKL1 as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy
Small, G. W., Akhtari, F. S., Green, A. J., Havener, T. M., Sikes, M., Quintanhila, J., … Wiltshire, T. (2023, June 7). Cells, Vol. 12.
2023 article
RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients
Gonzalez, R. D., Small, G. W., Green, A. J., Akhtari, F. S., Havener, T. M., Quintanilha, J. C. F., … Wiltshire, T. (2023, May 10). Pharmaceuticals, Vol. 16.
2023 article
Uncovering the common factors of chemical exposure and behavior: Evaluating behavioral effects across a testing battery using factor analysis
Marinello, W. P., Gillera, S. E. A., Huang, L., Rollman, J., Reif, D. M., & Patisaul, H. B. (2023, October 31). NeuroToxicology, Vol. 99, pp. 264–273.
2023 article
Utilizing Aggregated Molecular Phenotype (AMP) Scores to Visualize Simultaneous Molecular Changes in Mass Spectrometry Imaging Data
Chappel, J. R., King, M. E., Fleming, J., Eberlin, L. S., Reif, D. M., & Baker, E. S. (2023, June 5).
2022 journal article
Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response
Public Health Reports, 137(4), 803–812.
2022 article
Demonstrating a systems approach for integrating disparate data streams to inform decisions on children’s environmental health
Hubal, E. A. C., DeLuca, N. M., Mullikin, A., Slover, R., Little, J. C., & Reif, D. M. (2022, February 15). BMC Public Health, Vol. 2.
2022 article
Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish
Truong, L., Rericha, Y., Thunga, P., Marvel, S., Wallis, D., Simonich, M. T., … Tanguay, R. L. (2022, March 2). Journal of Hazardous Materials, Vol. 6, p. 128615.
2022 article
TCDD alters essential transcriptional regulators of osteogenic differentiation in multipotent mesenchymal stem cells
Watson, A. L. T. D., Baez, A. C., Jima, D., Reif, D., Ding, J., Roberts, R., & Kullman, S. W. (2022, November 11). Toxicological Sciences, Vol. 11, pp. 149–162.
2022 article
The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior
Shankar, P., Garcia, G. R., Du, J. K. L., Sullivan, C. M., Dunham, C. L., Goodale, B. C., … Tanguay, R. L. (2022, April 4). Toxicological Sciences, Vol. 4.
2022 article
ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS
Fleming, J., Marvel, S. W., Supak, S., Motsinger-Reif, A. A., & Reif, D. M. (2022, April 26). Journal of Exposure Science & Environmental Epidemiology, Vol. 4.
2022 article
Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS)
Kirkwood, K. I., Fleming, J., Nguyen, H., Reif, D. M., Baker, E. S., & Belcher, S. M. (2022, February 17). Environmental Science & Technology, Vol. 2.
2022 article
Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure
Thunga, P., Truong, L., Rericha, Y., Du, J., Morshead, M., Tanguay, R., & Reif, D. (2022, December 9). Toxics, Vol. 10.
2022 article
Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke
Carberry, C. K., Koval, L. E., Payton, A., Hartwell, H., Kim, Y. H., Smith, G. J., … Rager, J. E. (2022, July 16). Environment International, Vol. 9.
2021 article
Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification
Thunga, P., Truong, L., Tanguay, R. L., & Reif, D. M. (2021, June 15). Frontiers in Toxicology, Vol. 3.
2021 article
Development of a Pandemic Awareness STEM Outreach Curriculum: Utilizing a Computational Thinking Taxonomy Framework
Gilchrist, P. O., Alexander, A. B., Green, A. J., Sanders, F. E., Hooker, A. Q., & Reif, D. M. (2021, March 8). Education Sciences.
2021 article
Extending the Lymphoblastoid Cell Line Model for Drug Combination Pharmacogenomics
Green, A. J., Anchang, B., Akhtari, F. S., Reif, D. M., & Motsinger-Reif, A. (2021, May 28). Pharmacogenomics, Vol. 5.
2021 article
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs
Akhtari, F. S., Green, A. J., Small, G. W., Havener, T. M., House, J. S., Roell, K. R., … Motsinger-Reif, A. A. (2021, August 26). (F. Vazquez, Ed.). PLoS Genetics, Vol. 17, p. e1009732.
Ed(s): F. Vazquez
2021 article
Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology
Green, A. J., Mohlenkamp, M. J., Das, J., Chaudhari, M., Truong, L., Tanguay, R. L., & Reif, D. M. (2021, July 2). (V. Hatzimanikatis, Ed.). PLoS Computational Biology, Vol. 17, p. e1009135.
Ed(s): V. Hatzimanikatis
2021 article
Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments
Odenkirk, M. T., Reif, D. M., & Baker, E. S. (2021, May 24). Analytical Chemistry, Vol. 6.
2021 article
The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning
Marvel, S. W., House, J. S., Wheeler, M., Song, K., Zhou, Y.-H., Wright, F. A., … Reif, D. M. (2021, January 1). Environmental Health Perspectives, Vol. 129, pp. 017701–017701-017701–017703.
Contributors: S. Marvel n, J. House* , M. Wheeler *, K. Song n, Y. Zhou n , F. Wright n, W. Chiu *, I. Rusyn *, A. Motsinger-Reif*, n
2021 article
ToxPi*GIS Toolkit: Creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS
Fleming, J., Marvel, S. W., Motsinger-Reif, A. A., & Reif, D. M. (2021, October 11). (Vol. 10). Vol. 10.
2021 article
Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions
Wallis, D., Truong, L., Du, J. L., Tanguay, R., & Reif, D. (2021, April 6). Toxics, Vol. 9, p. 77.
2021 article
Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances
Kirkwood, K. I., Fleming, J., Nguyen, H., Reif, D. M., Baker, E. S., & Belcher, S. M. (2021, August 26). (Vol. 8). Vol. 8.
2020 article
In vivoassessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish
Phelps, D. W., Fletcher, A. A., Rodriguez-Nunez, I., Balik-Meisner, M. R., Tokarz, D. A., Reif, D. M., … Yoder, J. A. (2020, January 1). Journal of Immunotoxicology, Vol. 17, pp. 94–104.
2020 article
Bayesian Matrix Completion for Hypothesis Testing
(2020, September 17).
2020 article
Children’s Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals
Hubal, E. A. C., Reif, D. M., Slover, R., Mullikin, A., & Little, J. C. (2020, November 11). International Journal of Environmental Research and Public Health, Vol. 17, p. 8337.
2020 article
HGBEnviroScreen: Enabling Community Action through Data Integration in the Houston–Galveston–Brazoria Region
Bhandari, S., Lewis, P. G. T., Craft, E., Marvel, S. W., Reif, D. M., & Chiu, W. A. (2020, February 11). International Journal of Environmental Research and Public Health, Vol. 17, p. 1130.
2020 article
Structural-based connectivity and omic phenotype evaluations (SCOPE): a cheminformatics toolbox for investigating lipidomic changes in complex systems
Odenkirk, M. T., Zin, P. P. K., Ash, J. R., Reif, D. M., Fourches, D., & Baker, E. S. (2020, January 1). The Analyst, Vol. 145, pp. 7197–7209.
2020 article
The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: monitoring county level vulnerability
Marvel, S. W., House, J. S., Wheeler, M., Song, K., Zhou, Y., Wright, F. A., … Reif, D. M. (2020, August 13). MedRxiv, Vol. 8.
Contributors: S. Marvel n, J. House* , M. Wheeler *, K. Song n, Y. Zhou n, F. Wright n, W. Chiu *, I. Rusyn *, A. Motsinger-Reif *, n
2020 article
The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity
Truong, L., Marvel, S., Reif, D. M., Thomas, D. G., Pande, P., Dasgupta, S., … Tanguay, R. L. (2020, August 19). Reproductive Toxicology, Vol. 96, pp. 359–369.
2019 article
Associations between access to healthcare, environmental quality, and end-stage renal disease survival time: Proportional-hazards models of over 1,000,000 people over 14 years
Kosnik, M. B., Reif, D. M., Lobdell, D. T., Astell-Burt, T., Feng, X., Hader, J. D., & Hoppin, J. A. (2019, March 21). (W. Cheungpasitporn, Ed.). PLoS ONE, Vol. 14, p. e0214094.
Contributors: M. Kosnik n, n , D. Lobdell *, T. Astell-Burt *, X. Feng *, J. Hader*, J. Hoppin n
Ed(s): W. Cheungpasitporn
2019 article
Concentration–response evaluation of ToxCast compounds for multivariate activity patterns of neural network function
Kosnik, M. B., Strickland, J. D., Marvel, S. W., Wallis, D. J., Wallace, K., Richard, A. M., … Shafer, T. J. (2019, December 10). Archives of Toxicology, Vol. 94, pp. 469–484.
2019 article
Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases
Kosnik, M. B., & Reif, D. M. (2019, July 16). Toxicology and Applied Pharmacology, Vol. 379, p. 114674.
Contributors: M. Kosnik n & n
2019 article
Inappropriate Citation of Vaccine Article
Reif, D. M., Chanock, S. J., Edwards, K. M., & Crowe, J. E. (2019, May 30). The Journal of Infectious Diseases, Vol. 222, pp. 1413–1414.
2019 journal article
Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways
Computational Toxicology, 12, 100094.
Contributors: M. Kosnik n, A. Planchart n , S. Marvel n, n & C. Mattingly n
2019 article
Multivariate modeling of engineered nanomaterial features associated with developmental toxicity
To, K. T., Truong, L., Edwards, S., Tanguay, R. L., & Reif, D. M. (2019, April 1). NanoImpact, Vol. 16.
Contributors: K. To n, L. Truong *, S. Edwards *, R. Tanguay * & n
2019 article
Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes
Burnett, S. D., Blanchette, A. D., Grimm, F. A., House, J. S., Reif, D. M., Wright, F. A., … Rusyn, I. (2019, August 16). Toxicology and Applied Pharmacology, Vol. 381.
Contributors: S. Burnett *, A. Blanchette *, F. Grimm *, J. House n , n , F. Wright n, W. Chiu *, I. Rusyn *
2019 article
Sex-specific effects of perinatal FireMaster® 550 (FM 550) exposure on socioemotional behavior in prairie voles
Gillera, S. E. A., Marinello, W. P., Horman, B. M., Phillips, A. L., Ruis, M. T., Stapleton, H. M., … Patisaul, H. B. (2019, November 12). Neurotoxicology and Teratology, Vol. 79, p. 106840.
Contributors: S. Gillera n , W. Marinello n , B. Horman n, A. Phillips *, M. Ruis*, H. Stapleton *, n , H. Patisaul n
2019 article
Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines
Roell, K. R., Havener, T. M., Reif, D. M., Jack, J., McLeod, H. L., Wiltshire, T., & Motsinger-Reif, A. A. (2019, October 15). Frontiers in Genetics, Vol. 10.
Contributors: K. Roell n, T. Havener *, n , J. Jack n, H. McLeod *, T. Wiltshire *, A. Motsinger-Reif*
2019 article
Systematic determination of the relationship between nanoparticle core diameter and toxicity for a series of structurally analogous gold nanoparticles in zebrafish
Truong, L., Zaikova, T., Baldock, B. L., Balik-Meisner, M., To, K., Reif, D. M., … Tanguay, R. L. (2019, April 2). Nanotoxicology, Vol. 4, p. 1—15.
Contributors: L. Truong *, T. Zaikova *, B. Baldock *, M. Balik-Meisner n, K. To n, n , Z. Kennedy *, J. Hutchison *, R. Tanguay *
2018 article
Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi
To, K. T., Fry, R. C., & Reif, D. M. (2018, June 13). BioData Mining, Vol. 11.
2018 journal article
Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays
Scientific Reports, 8(1).
Contributors: D. Mahapatra n, J. Franzosa*, K. Roell n, M. Kuenemann n, K. Houck *, n , D. Fourches n, S. Kullman n
2018 journal article
Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays
Scientific Reports, 8.
2018 article
Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure
Balik-Meisner, M., Truong, L., Scholl, E. H., Du, J. K. L., Tanguay, R. L., & Reif, D. M. (2018, June 15). Environmental Health Perspectives, Vol. 6.
Contributors: M. Balik-Meisner n, L. Truong *, E. Scholl n, J. La Du*, R. Tanguay * & n
2018 article
Neonatal mice exposed to a high-fat diet in utero influence the behaviour of their nursing dam
Baptissart, M., Lamb, H. E., To, K., Bradish, C., Tehrani, J., Reif, D., & Cowley, M. (2018, November 14). Proceedings of the Royal Society B Biological Sciences, Vol. 285, p. 20181237.
Contributors: M. Baptissart n, H. Lamb n, K. To n, C. Bradish n , J. Tehrani n, n , M. Cowley n
2018 article
Population genetic diversity in zebrafish lines
Balik-Meisner, M., Truong, L., Scholl, E. H., Tanguay, R. L., & Reif, D. M. (2018, January 24). Mammalian Genome, Vol. 29, pp. 90–100.
Contributors: M. Balik-Meisner n, L. Truong *, E. Scholl n, R. Tanguay * & n
2018 article
ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models
Marvel, S. W., To, K., Grimm, F. A., Wright, F. A., Rusyn, I., & Reif, D. M. (2018, March 5). BMC Bioinformatics, Vol. 3.
Contributors: S. Marvel n, K. To n, F. Grimm *, F. Wright n, I. Rusyn * & n
2018 journal article
ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models
BMC Bioinformatics, 19.
2018 journal article
Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC monograph working groups
Altex-Alternatives to Animal Experimentation, 35(1), 51–64.
2017 article
A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish
Zhang, G., Truong, L., Tanguay, R. L., & Reif, D. M. (2017, January 18). (S. C. F. Neuhauss, Ed.). PLoS ONE, Vol. 12.
Contributors: G. Zhang n, L. Truong *, R. Tanguay * & n
Ed(s): S. Neuhauss
2017 article
An Introduction to Terminology and Methodology of Chemical Synergy—Perspectives from Across Disciplines
Roell, K. R., Reif, D. M., & Motsinger-Reif, A. A. (2017, April 20). Frontiers in Pharmacology, Vol. 8.
Contributors: K. Roell n, n & A. Motsinger-Reif n
2017 review
An introduction to terminology and methodology of chemical synergy-perspectives from across disciplines
[Review of ]. Frontiers in Pharmacology, 8.
2017 article
Incorporating ToxCast and Tox21 datasets to rank biological activity of chemicals at Superfund sites in North Carolina
Tilley, S. K., Reif, D. M., & Fry, R. C. (2017, January 31). Environment International, Vol. 101, pp. 19–26.
Contributors: S. Tilley *, n & R. Fry *
2017 article
Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish
Zhang, G., Truong, L., Tanguay, R. L., & Reif, D. M. (2017, January 1). The Rights and Wrongs of Zebrafish: Behavioral Phenotyping of Zebrafish, pp. 259–272.
Contributors: G. Zhang n, L. Truong *, R. Tanguay * & n
2017 article
Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish
Knecht, A. L., Truong, L., Marvel, S. W., Reif, D. M., Garcia, A., Lu, C., … Tanguay, R. L. (2017, June 3). Toxicology and Applied Pharmacology, Vol. 8, pp. 148–157.
Contributors: A. Knecht*, L. Truong *, S. Marvel n, n , A. Garcia*, C. Lu *, M. Simonich *, J. Teeguarden *, R. Tanguay *
2017 article
Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups
Chiu, W. A., Guyton, K. Z., Martin, M. T., Reif, D. M., & Rusyn, I. (2017, July 24). ALTEX, Vol. 35, pp. 51–64.
Contributors: W. Chiu *, K. Guyton, M. Martin, & I. Rusyn
2016 article
A chemical–biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives
Grimm, F. A., Iwata, Y., Sirenko, O., Chappell, G. A., Wright, F. A., Reif, D. M., … Rusyn, I. (2016, January 1). Green Chemistry, Vol. 8, pp. 4407–4419.
Contributors: F. Grimm *, Y. Iwata*, O. Sirenko*, G. Chappell *, F. Wright n, n , J. Braisted *, D. Gerhold *
2016 article
A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades
Zhang, G., Roell, K. R., Truong, L., Tanguay, R. L., & Reif, D. M. (2016, November 22). Toxicology and Applied Pharmacology, Vol. 314, pp. 109–117.
Contributors: G. Zhang n, K. Roell n, L. Truong *, R. Tanguay * & n
2016 journal article
Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database
Environmental Health Perspectives, 124(10), 1592–1599.
Contributors: C. Grondin n, A. Davis n, T. Wiegers n, B. King *, J. Wiegers n, n , J. Hoppin n , C. Mattingly n
2016 journal article
Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database.
Environmental Health Perspectives, 10. http://europepmc.org/abstract/med/27170236
2016 journal article
Advancing toxicology research using in vivo high throughput toxicology with small fish models
ALTEX, 33(4), 435–452.
Contributors: A. Planchart n , C. Mattingly, D. Allen, P. Ceger, W. Casey, D. Hinton, J. Kanungo, S. Kullman
2016 journal article
Advancing toxicology research using in vivo high throughput toxicology with small fish models
Altex-Alternatives to Animal Experimentation, 33(4), 435–452.
2016 article
Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure
Zhang, G., Marvel, S., Truong, L., Tanguay, R. L., & Reif, D. M. (2016, April 30). Reproductive Toxicology, Vol. 62, pp. 92–99.
Contributors: G. Zhang n, S. Marvel n, L. Truong *, R. Tanguay * & n
2016 article
Analysis of the Effects of Cell Stress and Cytotoxicity onIn Vitro Assay Activity Across a Diverse Chemical and Assay Space
Judson, R., Houck, K., Martin, M., Richard, A. M., Knudsen, T. B., Shah, I., … Thomas, R. S. (2016, September 7). Toxicological Sciences, Vol. 10, pp. 409–409.
Contributors: R. Judson *, K. Houck *, M. Martin*, A. Richard *, T. Knudsen *, I. Shah *, S. Little *, J. Wambaugh *
2016 journal article
Decoupling of a neutron interferometer from temperature gradients
Review of Scientific Instruments, 87(12), 123507.
2016 article
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity onIn VitroAssay Activity Across a Diverse Chemical and Assay Space
Judson, R., Houck, K., Martin, M., Richard, A. M., Knudsen, T. B., Shah, I., … Thomas, R. S. (2016, May 20). Toxicological Sciences, Vol. 8, pp. 323–339.
Contributors: R. Judson *, K. Houck *, M. Martin*, A. Richard *, T. Knudsen *, I. Shah *, S. Little *, J. Wambaugh *
2016 article
Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes
Chialvo, C. H. S., Che, R., Reif, D., Motsinger-Reif, A., & Reed, L. K. (2016, September 20). Metabolomics, Vol. 12.
Contributors: C. Scott Chialvo *, R. Che n, n , A. Motsinger-Reif n & L. Reed *
2016 article
Evolutionary and Functional Diversification of the Vitamin D Receptor-Lithocholic Acid Partnership
Kollitz, E. M., Zhang, G., Hawkins, M. B., Whitfield, G. K., Reif, D. M., & Kullman, S. W. (2016, December 12). (C. Zhang, Ed.). PLoS ONE, Vol. 11, p. e0168278.
Contributors: E. Kollitz n, G. Zhang n, M. Hawkins n, G. Whitfield*, n & S. Kullman n
Ed(s): C. Zhang n
2016 journal article
From the Cover: Embryonic Exposure to TCDD Impacts Osteogenesis of the Axial Skeleton in Japanese medaka,Oryzias latipes
Toxicological Sciences, 155(2), 485–496.
Contributors: A. Watson*, A. Planchart n , C. Mattingly n , C. Winkler *, n & S. Kullman n
2016 journal article
Lifetime substance use as a predictor of postpartum mental health
Archives of Women's Mental Health, 20(1), 189–199.
2016 article
Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast™ High-Throughput Data
Auerbach, S., Filer, D., Reif, D., Walker, V., Holloway, A. C., Schlezinger, J., … Thayer, K. A. (2016, March 15). Environmental Health Perspectives, Vol. 124, pp. 1141–1154.
Contributors: S. Auerbach *, D. Filer *, n , V. Walker *, A. Holloway*, J. Schlezinger *, S. Srinivasan *, D. Svoboda*
2016 journal article
Using ToxCast (TM) data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure
Environmental Health Perspectives, 124(7), 910–919.
2015 article
Carcinogenicity of lindane, DDT, and 2,4-dichlorophenoxyacetic acid
Loomis, D., Guyton, K., Grosse, Y., El, G. F., Bouvard, V., Benbrahim-Tallaa, L., … France. (2015, June 23). The Lancet Oncology, Vol. 8.
2015 article
Computational Methods Used in Systems Biology
Meisner, M., & Reif, D. M. (2015, January 1). Elsevier EBooks, pp. 85–115.
2015 article
Data-Driven Asthma Endotypes Defined from Blood Biomarker and Gene Expression Data
George, B. J., Reif, D. M., Gallagher, J. E., Williams-DeVane, C. L. R., Heidenfelder, B. L., Hudgens, E. E., … Edwards, S. W. (2015, February 2). PLoS ONE, Vol. 10.
Contributors: B. George *, * , J. Gallagher*, C. Williams-DeVane *, B. Heidenfelder*, E. Hudgens *, W. Jones *, L. Neas *, E. Cohen Hubal*, S. Edwards *
2015 article
Genomics and Proteomics
Bentley, W. E., & Toghrol, F. (2015, June 9). Apple Academic Press EBooks, pp. 19–58.
2015 article
High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes
Reif, D. M., Truong, L., Mandrell, D., Marvel, S., Zhang, G., & Tanguay, R. L. (2015, June 30). Archives of Toxicology, Vol. 90, pp. 1459–1470.
Contributors: n , L. Truong *, D. Mandrell*, S. Marvel n, G. Zhang n & R. Tanguay *
2015 article
Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study
Rebuli, M. E., Camacho, L., Adonay, M. E., Reif, D. M., Aylor, D. L., & Patisaul, H. B. (2015, July 23). Toxicological Sciences, Vol. 148, pp. 341–354.
Contributors: M. Rebuli n, L. Camacho *, M. Adonay n, n , D. Aylor n & H. Patisaul n
2015 article
Molecular Cloning, Functional Characterization, and Evolutionary Analysis of Vitamin D Receptors Isolated from Basal Vertebrates
Kollitz, E. M., Zhang, G., Hawkins, M. B., Whitfield, G. K., Reif, D. M., & Kullman, S. W. (2015, April 9). PLoS ONE, Vol. 10.
Contributors: E. Kollitz n, G. Zhang n, M. Hawkins n, G. Whitfield*, n & S. Kullman n
2015 article
Toxicity testing in the 21st century beyond environmental chemicals
Rovida, C., Asakura, S., Daneshian, M., Hofman-Huether, H., Leist, M., Meunier, L., … Hartung, T. (2015, January 1). ALTEX, Vol. 32, pp. 171–181.
Contributors: C. Rovida *, S. Asakura*, M. Daneshian*, H. Hofman-Huether*, M. Leist *, L. Meunier *, n , A. Rossi*
2015 article
Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure
Shah, I., Setzer, R. W., Jack, J., Houck, K. A., Judson, R. S., Knudsen, T. B., … Kavlock, R. J. (2015, October 16). Environmental Health Perspectives, Vol. 124, pp. 910–919.
Contributors: I. Shah *, R. Setzer *, J. Jack n, K. Houck *, R. Judson *, T. Knudsen *, J. Liu *, M. Martin *
2014 article
Comparison of toxicity values across zebrafish early life stages and mammalian studies: Implications for chemical testing
Ducharme, N. A., Reif, D. M., Gustafsson, J.-A., & Bondesson, M. (2014, September 28). Reproductive Toxicology, Vol. 55, pp. 3–10.
Contributors: N. Ducharme *, n , J. Gustafsson * & M. Bondesson *
2014 article
Erratum
Rotroff, D. M., Wetmore, B. A., Dix, D. J., Ferguson, S. S., Clewell, H. J., Houck, K. A., … Thomas, R. S. (2014, January 30). Toxicological Sciences, Vol. 137.
Contributors: D. Rotroff, B. Wetmore, D. Dix, S. Ferguson, H. Clewell, K. Houck, E. LeCluyse, M. Andersen
2014 article
Hierarchical dose–response modeling for high‐throughput toxicity screening of environmental chemicals
Wilson, A., Reif, D. M., & Reich, B. J. (2014, January 7). Biometrics, Vol. 70, pp. 237–246.
Contributors: A. Wilson, n & B. Reich*
2014 article
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms
Kleinstreuer, N. C., Yang, J., Berg, E. L., Knudsen, T. B., Richard, A. M., Martin, M. T., … Houck, K. A. (2014, May 18). Nature Biotechnology, Vol. 32, pp. 583–591.
Contributors: N. Kleinstreuer *, J. Yang *, E. Berg *, T. Knudsen *, A. Richard *, M. Martin *, * , R. Judson *
2014 article
Predictive Endocrine Testing in the 21st Century Usingin VitroAssays of Estrogen Receptor Signaling Responses
Rotroff, D. M., Martin, M. T., Dix, D. J., Filer, D. L., Houck, K. A., Knudsen, T. B., … Judson, R. S. (2014, June 24). Environmental Science & Technology, Vol. 48, pp. 8706–8716.
Contributors: D. Rotroff *, M. Martin*, D. Dix*, D. Filer *, K. Houck *, T. Knudsen *, N. Sipes *, *
2014 article
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway
Huang, R., Sakamuru, S., Martin, M. T., Reif, D. M., Judson, R. S., Houck, K. A., … Xia, M. (2014, July 11). Scientific Reports, Vol. 4.
Contributors: R. Huang *, S. Sakamuru *, M. Martin*, * , R. Judson *, K. Houck *, W. Casey *, J. Hsieh *
2014 article
Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II
Filer, D., Patisaul, H. B., Schug, T., Reif, D., & Thayer, K. (2014, October 15). Current Opinion in Pharmacology, Vol. 19, pp. 145–152.
Contributors: D. Filer *, H. Patisaul n , T. Schug*, n & K. Thayer *
2014 journal article
ToxiFly: Can fruit flies be used to identify toxicity pathways for airborne chemicals?
Neurotoxicology and Teratology, 43, 89.
2013 article
A Computational Model Predicting Disruption of Blood Vessel Development
Kleinstreuer, N., Dix, D., Rountree, M., Baker, N., Sipes, N., Reif, D., … Knudsen, T. (2013, April 4). (S. M. Peirce, Ed.). PLoS Computational Biology, Vol. 9, p. e1002996.
Contributors: N. Kleinstreuer *, D. Dix*, M. Rountree *, N. Baker *, N. Sipes *, * , R. Spencer*, T. Knudsen *
Ed(s): S. Peirce
2013 article
Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer’s disease from normal cognitive aging
Motsinger-Reif, A. A., Zhu, H., Kling, M. A., Matson, W., Sharma, S., Fiehn, O., … Arnold, S. E. (2013, June 27). Acta Neuropathologica Communications, Vol. 1, p. 28.
Contributors: A. Motsinger-Reif n, H. Zhu *, M. Kling *, W. Matson*, S. Sharma *, O. Fiehn *, n , D. Appleby*
2013 article
Decision tree-based method for integrating gene expression, demographic, and clinical data to determine disease endotypes
Williams-DeVane, C. L. R., Reif, D. M., Hubal, E. C., Bushel, P. R., Hudgens, E. E., Gallagher, J. E., & Edwards, S. W. (2013, January 1). BMC Systems Biology, Vol. 7, p. 119.
Contributors: C. Williams-DeVane *, * , E. Hubal*, P. Bushel *, E. Hudgens *, J. Gallagher*, S. Edwards *
2013 article
Dosimetric Anchoring of In Vivo and In Vitro Studies for Perfluorooctanoate and Perfluorooctanesulfonate
Wambaugh, J. F., Setzer, R. W., Pitruzzello, A. M., Liu, J., Reif, D. M., Kleinstreuer, N. C., … Lau, C. (2013, September 17). Toxicological Sciences, Vol. 136, pp. 308–327.
Contributors: J. Wambaugh *, R. Setzer *, A. Pitruzzello*, J. Liu *, * , N. Kleinstreuer *, N. Wang*, N. Sipes *
2013 article
High-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project
Wambaugh, J. F., Setzer, R. W., Reif, D. M., Gangwal, S., Mitchell-Blackwood, J., Arnot, J. A., … E.A. (2013, June 12). Environmental Science & Technology, Vol. 47, pp. 8479–8488.
Contributors: J. Wambaugh *, R. Setzer *, * , S. Gangwal*, J. Mitchell-Blackwood*, J. Arnot *, O. Joliet*, A. Frame*
2013 article
Meta-analysis of toxicity and teratogenicity of 133 chemicals from zebrafish developmental toxicity studies
Ducharme, N. A., Peterson, L. E., Benfenati, E., Reif, D., McCollum, C. W., Gustafsson, J.-Å., & Bondesson, M. (2013, June 22). Reproductive Toxicology, Vol. 41, pp. 98–108.
Contributors: N. Ducharme *, L. Peterson *, E. Benfenati *, * , C. McCollum *, J. Gustafsson *, M. Bondesson *
2013 article
Multidimensional In Vivo Hazard Assessment Using Zebrafish
Truong, L., Reif, D. M., Mary, L. S., Geier, M. C., Truong, H. D., & Tanguay, R. L. (2013, October 17). Toxicological Sciences, Vol. 137, pp. 212–233.
Contributors: L. Truong *, n , L. Mary *, M. Geier*, H. Truong* & R. Tanguay *
2013 journal article
Perspectives on validation of high-throughput assays supporting 21st century toxicity testing.
Altex, 30(1), 51–66. http://europepmc.org/abstract/med/23338806
2013 article
Profiling 976 ToxCast Chemicals across 331 Enzymatic and Receptor Signaling Assays
Sipes, N. S., Martin, M. T., Kothiya, P., Reif, D. M., Judson, R. S., Richard, A. M., … Knudsen, T. B. (2013, April 23). Chemical Research in Toxicology, Vol. 26, p. 878â895.
Contributors: N. Sipes *, M. Martin *, P. Kothiya *, * , R. Judson *, A. Richard *, K. Houck *, D. Dix*, R. Kavlock*, T. Knudsen *
2013 article
Real-Time Growth Kinetics Measuring Hormone Mimicry for ToxCast Chemicals in T-47D Human Ductal Carcinoma Cells
Rotroff, D. M., Dix, D. J., Houck, K. A., Kavlock, R. J., Knudsen, T. B., Martin, M. T., … Judson, R. S. (2013, May 17). Chemical Research in Toxicology, Vol. 26, pp. 1097–1107.
Contributors: D. Rotroff *, D. Dix*, K. Houck *, R. Kavlock*, T. Knudsen *, M. Martin *, * , A. Richard *
2013 article
ToxCast: Predicting Toxicity Potential Through High‐Throughput Bioactivity Profiling
Houck, K. A., Richard, A. M., Judson, R. S., Martin, M. T., Reif, D. M., & Shah, I. (2013, February 13). High-Throughput Screening Methods in Toxicity Testing, Vol. 2, p. 1â31.
Contributors: K. Houck *, A. Richard *, R. Judson *, M. Martin *, * & I. Shah *
2012 article
A comparison of GE optimized neural networks and decision trees
Hoover, K., Marceau, R., Harris, T., Reif, D., & Motsinger-Reif, A. (2012, July 7). Proceedings of the Fourteenth International Conference on Genetic and Evolutionary Computation Conference Companion - GECCO Companion '12, pp. 611–614.
Contributors: K. Hoover, n , R. Marceau n, T. Harris n & A. Motsinger-Reif n
2012 article
A comparison of internal model validation methods for multifactor dimensionality reduction in the case of genetic heterogeneity
Gory, J. J., Sweeney, H. C., Reif, D. M., & Motsinger-Reif, A. A. (2012, November 5). BMC Research Notes, Vol. 5, p. 623.
Contributors: J. Gory n, H. Sweeney n, n & A. Motsinger-Reif n
2012 article
Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System
Judson, R. S., Martin, M. T., Egeghy, P., Gangwal, S., Reif, D. M., Kothiya, P., … A.M. (2012, February 9). International Journal of Molecular Sciences, Vol. 13, pp. 1805–1831.
Contributors: R. Judson *, M. Martin *, P. Egeghy *, S. Gangwal*, * , P. Kothiya *, M. Wolf*, T. Cathey *
2012 article
In Vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis
Kleinstreuer, N. C., Dix, D. J., Houck, K. A., Kavlock, R. J., Knudsen, T. B., Martin, M. T., … Judson, R. S. (2012, September 28). Toxicological Sciences, Vol. 131, pp. 40–55.
Contributors: N. Kleinstreuer *, D. Dix*, K. Houck *, R. Kavlock*, T. Knudsen *, M. Martin *, K. Paul*, *
2012 article
Incorporating Biological, Chemical, and Toxicological Knowledge Into Predictive Models of Toxicity
Dix, D. J., Houck, K. A., Judson, R. S., Kleinstreuer, N. C., Knudsen, T. B., Martin, M. T., … Kavlock, R. J. (2012, September 14). Toxicological Sciences, Vol. 130, pp. 440–441.
Contributors: D. Dix*, K. Houck *, R. Judson *, N. Kleinstreuer *, T. Knudsen *, M. Martin *, * , A. Richard *
2012 article
Incorporating exposure information into the toxicological prioritization index decision support framework
Gangwal, S., Reif, D. M., Mosher, S., Egeghy, P. P., Wambaugh, J. F., Judson, R. S., & Hubal, E. A. C. (2012, August 2). The Science of The Total Environment, Vol. 435-436, p. 316â325.
Contributors: S. Gangwal*, * , S. Mosher*, P. Egeghy *, J. Wambaugh *, R. Judson *, E. Hubal*
2012 article
ToxPi GUI: an interactive visualization tool for transparent integration of data from diverse sources of evidence
Reif, D. M., Sypa, M., Lock, E. F., Wright, F. A., Wilson, A., Cathey, T., … Rusyn, I. (2012, November 29). Bioinformatics, Vol. 29, pp. 402–403.
Contributors: * , M. Sypa*, E. Lock *, F. Wright *, A. Wilson *, T. Cathey *, R. Judson *, I. Rusyn *
2012 article
Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management
Kavlock, R., Chandler, K., Houck, K., Hunter, S., Judson, R., Kleinstreuer, N., … Dix, D. (2012, April 21). Chemical Research in Toxicology, Vol. 25, p. 1287â1302.
Contributors: R. Kavlock*, K. Chandler*, K. Houck *, S. Hunter*, R. Judson *, N. Kleinstreuer *, T. Knudsen *, M. Martin *
2012 article
Usingin VitroHigh Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals
Rotroff, D. M., Dix, D. J., Houck, K. A., Knudsen, T. B., Martin, M. T., McLaurin, K. W., … Judson, R. S. (2012, November 19). Environmental Health Perspectives, Vol. 121, pp. 7–14.
Contributors: D. Rotroff *, D. Dix, K. Houck, T. Knudsen, M. Martin, K. McLaurin, * , K. Crofton *
2011 article
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets
Knudsen, T. B., Houck, K. A., Sipes, N. S., Singh, A. V., Judson, R. S., Martin, M. T., … Kavlock, R. J. (2011, January 19). Toxicology, Vol. 282, p. 1â15.
Contributors: T. Knudsen *, K. Houck *, N. Sipes *, A. Singh *, R. Judson *, M. Martin *, A. Weissman, N. Kleinstreuer *
2011 article
Environmental Impact on Vascular Development Predicted by High-Throughput Screening
Kleinstreuer, N. C., Judson, R. S., Reif, D. M., Sipes, N. S., Singh, A. V., Chandler, K. J., … Knudsen, T. B. (2011, July 25). Environmental Health Perspectives, Vol. 119, p. 1596â1603.
Contributors: N. Kleinstreuer *, R. Judson *, * , N. Sipes *, A. Singh *, K. Chandler*, R. DeWoskin*, D. Dix*, R. Kavlock*, T. Knudsen *
2011 article
Evaluation of 309 Environmental Chemicals Using a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity Assay
Chandler, K. J., Barrier, M., Jeffay, S., Nichols, H. P., Kleinstreuer, N. C., Singh, A. V., … Knudsen, T. B. (2011, June 7). (A. J. Cooney, Ed.). PLoS ONE, Vol. 6, p. e18540.
Contributors: K. Chandler*, M. Barrier*, S. Jeffay*, H. Nichols*, N. Kleinstreuer *, A. Singh *, * , N. Sipes *
Ed(s): A. Cooney
2011 article
Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population
Joubert, B. R., Reif, D. M., Edwards, S. W., Leiner, K. A., Hudgens, E. E., Egeghy, P., … Hubal, E. C. (2011, February 14). BMC Medical Genetics, Vol. 12, p. 25.
Contributors: B. Joubert *, * , S. Edwards *, K. Leiner*, E. Hudgens *, P. Egeghy *, J. Gallagher*, E. Hubal
2011 article
Mechanistic Indicators of Childhood Asthma (MICA) Study: piloting an integrative design for evaluating environmental health
Gallagher, J., Hudgens, E., Williams, A., Inmon, J., Rhoney, S., Andrews, G., … Hubal, E. C. (2011, May 19). BMC Public Health, Vol. 11, p. 344.
Contributors: J. Gallagher*, E. Hudgens *, A. Williams*, J. Inmon*, S. Rhoney*, G. Andrews*, * , B. Heidenfelder*
2011 article
Optimization of grammatical evolution decision trees
Hoover, K., Marceau, R., Harris, T., Hardison, N., Reif, D., & Motsinger-Reif, A. (2011, July 12). Proceedings of the 13th Annual Conference Companion on Genetic and Evolutionary Computation - GECCO '11, pp. 35–36.
Contributors: K. Hoover n, R. Marceau n, T. Harris n, N. Hardison n, n & A. Motsinger-Reif n
2011 article
Predictive Model of Rat Reproductive Toxicity from ToxCast High Throughput Screening1
Martin, M. T., Knudsen, T. B., Reif, D. M., Houck, K. A., Judson, R. S., Kavlock, R. J., & Dix, D. J. (2011, May 13). Biology of Reproduction, Vol. 85, pp. 327–339.
Contributors: M. Martin *, T. Knudsen *, * , K. Houck *, R. Judson *, R. Kavlock*, D. Dix*
2011 article
Predictive Models of Prenatal Developmental Toxicity from ToxCast High-Throughput Screening Data
Sipes, N. S., Martin, M. T., Reif, D. M., Kleinstreuer, N. C., Judson, R. S., Singh, A. V., … Knudsen, T. B. (2011, August 26). Toxicological Sciences, Vol. 124, pp. 109–127.
Contributors: N. Sipes *, M. Martin *, * , N. Kleinstreuer *, R. Judson *, A. Singh *, K. Chandler*, D. Dix*, R. Kavlock*, T. Knudsen *
2011 article
Using Nuclear Receptor Activity to Stratify Hepatocarcinogens
Shah, I., Houck, K., Judson, R. S., Kavlock, R. J., Martin, M. T., Reif, D. M., … Dix, D. J. (2011, February 14). (S. Wölfl, Ed.). PLoS ONE, Vol. 6.
Contributors: I. Shah *, K. Houck *, R. Judson *, R. Kavlock*, M. Martin *, * , J. Wambaugh *, D. Dix*
Ed(s): S. Wölfl
2011 article
Zebrafish developmental screening of the ToxCast™ Phase I chemical library
Padilla, S., Corum, D., Padnos, B., Hunter, D. L., Beam, A., Houck, K. A., … Reif, D. M. (2011, December 11). Reproductive Toxicology, Vol. 33, pp. 174–187.
Contributors: S. Padilla *, D. Corum*, B. Padnos*, D. Hunter *, A. Beam *, K. Houck *, N. Sipes *, N. Kleinstreuer *
2010 article
Analysis of Eight Oil Spill Dispersants Using Rapid, In Vitro Tests for Endocrine and Other Biological Activity
Judson, R. S., Martin, M. T., Reif, D. M., Houck, K. A., Knudsen, T. B., Rotroff, D. M., … Dix, D. J. (2010, July 6). Environmental Science & Technology, Vol. 44, pp. 5979–5985.
Contributors: R. Judson *, M. Martin *, * , K. Houck *, T. Knudsen *, D. Rotroff *, M. Xia *, S. Sakamuru *
2010 article
Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data
Reif, D. M., Martin, M. T., Tan, S. W., Houck, K. A., Judson, R. S., Richard, A. M., … Kavlock, R. J. (2010, September 8). Environmental Health Perspectives, Vol. 118, p. 1714â1720.
Contributors: * , M. Martin *, S. Tan*, K. Houck *, R. Judson *, A. Richard *, T. Knudsen *, D. Dix*, R. Kavlock*
2010 article
Impact of Environmental Chemicals on Key Transcription Regulators and Correlation to Toxicity End Points within EPA’s ToxCast Program
Martin, M. T., Dix, D. J., Judson, R. S., Kavlock, R. J., Reif, D. M., Richard, A. M., … Houck, K. A. (2010, February 10). Chemical Research in Toxicology, Vol. 23, pp. 578–590.
Contributors: M. Martin *, D. Dix*, R. Judson *, R. Kavlock*, * , A. Richard *, D. Rotroff *, S. Romanov*
2010 article
Incorporating Human Dosimetry and Exposure into High-ThroughputIn VitroToxicity Screening
Rotroff, D. M., Wetmore, B. A., Dix, D. J., Ferguson, S. S., Clewell, H. J., Houck, K. A., … Thomas, R. S. (2010, July 16). Toxicological Sciences, Vol. 117, pp. 348–358.
Contributors: D. Rotroff *, B. Wetmore *, D. Dix*, S. Ferguson, H. Clewell *, K. Houck *, E. LeCluyse, M. Andersen *
2010 article
Xenobiotic-Metabolizing Enzyme and Transporter Gene Expression in Primary Cultures of Human Hepatocytes Modulated by Toxcast Chemicals
Rotroff, D. M., Beam, A. L., Dix, D. J., Farmer, A., Freeman, K. M., Houck, K. A., … Ferguson, S. S. (2010, June 17). Journal of Toxicology and Environmental Health Part B, Vol. 13, pp. 329–346.
Contributors: D. Rotroff *, A. Beam, D. Dix*, A. Farmer, K. Freeman, K. Houck *, R. Judson *, E. Lecluyse
2009 article
In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project
Judson, R. S., Houck, K. A., Kavlock, R. J., Knudsen, T. B., Martin, M. T., Mortensen, H. M., … Dix, D. J. (2009, December 14). Environmental Health Perspectives, Vol. 118, p. 485â492.
Contributors: R. Judson *, K. Houck *, R. Kavlock*, T. Knudsen *, M. Martin *, H. Mortensen *, * , D. Rotroff *
2009 article
A comparison of analytical methods for genetic association studies
Motsinger‐Reif, A. A., Reif, D. M., Fanelli, T. J., & Ritchie, M. D. (2009, March 17). Genetic Epidemiology, Vol. 33, p. 751â751.
Contributors: A. Motsinger-Reif n, * , T. Fanelli* & M. Ritchie *
2009 article
Comparative Microarray Analysis and Pulmonary Changes in Brown Norway Rats Exposed to Ovalbumin and Concentrated Air Particulates
Heidenfelder, B. L., Reif, D. M., Harkema, J. R., Hubal, E. A. C., Hudgens, E. E., Bramble, L. A., … Gallagher, J. E. (2009, January 27). Toxicological Sciences, Vol. 108, pp. 207–221.
Contributors: B. Heidenfelder*, * , J. Harkema *, E. Cohen Hubal*, E. Hudgens *, L. Bramble*, J. Wagner *, M. Morishita *
2009 article
Research needs for community-based risk assessment: findings from a multi-disciplinary workshop
Sanchez, Y. A., Deener, K., Hubal, E. C., Knowlton, C., Reif, D., & Segal, D. (2009, February 25). Journal of Exposure Science & Environmental Epidemiology, Vol. 20, p. 186â195.
Contributors: Y. Sanchez*, K. Deener*, E. Hubal*, C. Knowlton*, * & D. Segal *
2008 article
A balanced accuracy fitness function leads to robust analysis using grammatical evolution neural networks in the case of class imbalance
Hardison, N. E., Fanelli, T. J., Dudek, S. M., Reif, D. M., Ritchie, M. D., & Motsinger-Reif, A. A. (2008, July 12). Proceedings of the 10th Annual Conference on Genetic and Evolutionary Computation - GECCO '08.
2008 conference paper
A balanced accuracy fitness function leads to robust analysis using grammatical evolution neural networks in the case of class imbalance
GECCO'08: Proceedings of the 10th Annual Conference on Genetic and Evolutionary Computation 2008, 353–354. http://www.scopus.com/inward/record.url?eid=2-s2.0-57349087730&partnerID=MN8TOARS
2008 article
A comparison of analytical methods for genetic association studies
Motsinger‐Reif, A. A., Reif, D. M., Fanelli, T. J., & Ritchie, M. D. (2008, June 16). Genetic Epidemiology, Vol. 32, p. 767â778.
Contributors: A. Motsinger-Reif n, * , T. Fanelli* & M. Ritchie *
2008 journal article
Genetic Basis for Adverse Events after Smallpox Vaccination
The Journal of Infectious Diseases, 198(1), 16–22.
Contributors: * , B. McKinney *, A. Motsinger*, S. Chanock *, K. Edwards *, M. Rock*, J. Moore, J. Crowe Jr. *
2008 article
Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination
Reif, D. M., Motsinger-Reif, A. A., McKinney, B. A., Rock, M. T., Crowe, J. E., & Moore, J. H. (2008, October 16). Genes and Immunity, Vol. 10, pp. 112–119.
Contributors: * , A. Motsinger-Reif n, B. McKinney *, M. Rock*, J. Crowe Jr. * & J. Moore *
2008 article
Profiling Chemicals Based on Chronic Toxicity Results from the U.S. EPA ToxRef Database
Martin, M. T., Judson, R. S., Reif, D. M., Kavlock, R. J., & Dix, D. J. (2008, October 19). Environmental Health Perspectives, Vol. 117, p. 392â399.
Contributors: M. Martin *, R. Judson *, * , R. Kavlock* & D. Dix*
2008 article
Reif et al. (2008; 198:16–22)
Reif, D. M., McKinney, B. A., & Motsinger, A. A. (2008, August 11). The Journal of Infectious Diseases, Vol. 198.
2007 article
Evaporative cooling feature selection for genotypic data involving interactions
McKinney, B. A., Reif, D. M., White, B. C., Crowe, J. E., & Moore, J. H. (2007, June 22). Bioinformatics, Vol. 23, pp. 2113–2120.
Contributors: B. McKinney *, * , B. White *, J. Crowe Jr. * & J. Moore *
2007 journal article
Exploratory Visual Analysis of statistical results from microarray experiments comparing high and low grade glioma.
Cancer Informatics, 5, 19–24. http://europepmc.org/abstract/med/19390666
2007 journal article
Linkage Disequilibrium in Genetic Association Studies Improves the Performance of Grammatical Evolution Neural Networks.
Proceedings of the ... IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology. IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, 2007, 1–8. http://europepmc.org/abstract/med/21572972
2007 conference paper
Linkage disequilibrium in genetic association studies improves the performance of grammatical evolution neural networks
2007 IEEE Symposium on Computational Intelligence and Bioinformatics and Computational Biology, CIBCB 2007, 1–8. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650698880&partnerID=MN8TOARS
2007 article
Novel Methods for Detecting Epistasis in Pharmacogenomics Studies
Motsinger, A. A., Ritchie, M. D., & Reif, D. M. (2007, September 1). Pharmacogenomics, Vol. 8, p. 1229â1241.
Contributors: A. Motsinger n, M. Ritchie * & *
2006 article
Cytokine Expression Patterns Associated with Systemic Adverse Events following Smallpox Immunization
McKinney, B. A., Reif, D. M., Rock, M. T., Edwards, K. M., Kingsmore, S. F., Moore, J. H., & Crowe, J. E., Jr. (2006, July 25). The Journal of Infectious Diseases, Vol. 194, pp. 444–453.
Contributors: B. McKinney *, * , M. Rock*, K. Edwards *, S. Kingsmore *, J. Moore, J. Crowe Jr. *
2006 article
Feature Selection using a Random Forests Classifier for the Integrated Analysis of Multiple Data Types
Reif, D. M., Motsinger, A. A., McKinney, B. A., Crowe, J. E., & Moore, J. H. (2006, September 1). Proceedings of the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB'06, pp. 171–178.
Contributors: * , A. Motsinger *, B. McKinney *, J. Crowe Jr. * & J. Moore
2006 article
Integrated analysis of genetic and proteomic data.
http://europepmc.org/theses/ETH/7299
2006 article
Machine Learning for Detecting Gene-Gene Interactions
McKinney, B. A., Reif, D. M., Ritchie, M. D., & Moore, J. H. (2006, January 1). Applied Bioinformatics, Vol. 5, p. 77â88.
Contributors: B. McKinney *, * , M. Ritchie * & J. Moore *
2006 article
Understanding the Evolutionary Process of Grammatical Evolution Neural Networks for Feature Selection in Genetic Epidemiology
Motsinger, A. A., Reif, D. M., Dudek, S. M., & Ritchie, M. D. (2006, September 1). Proceedings of the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB'06, pp. 263–270.
Contributors: A. Motsinger *, * , S. Dudek * & M. Ritchie *
2006 article
Visual analysis of statistical results from microarray studies of human breast cancer
Reif, D., & Moore, J. (2006, April 1). Oncology Reports, Vol. 4, pp. 1043–1047.
Contributors: * & J. Moore *
2006 journal article
Visual analysis of statistical results from microarray studies of human breast cancer
Oncology Reports, 15(4), 1043–1047. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645789817&partnerID=MN8TOARS
2005 conference paper
A statistical comparison of grammatical evolution strategies in the domain of human genetics
2005 IEEE Congress on Evolutionary Computation, IEEE CEC 2005. Proceedings, 1, 676–682. http://www.scopus.com/inward/record.url?eid=2-s2.0-27144535907&partnerID=MN8TOARS
2005 article
Combinatorial Pharmacogenetics
Wilke, R. A., Reif, D. M., & Moore, J. H. (2005, November 1). Nature Reviews Drug Discovery, Vol. 4, p. 911â918.
Contributors: R. Wilke *, * & J. Moore *
2005 conference paper
Exploratory visual analysis of pharmacogenomic results
Proceedings of the Pacific Symposium on Biocomputing 2005, PSB 2005, 296–307. http://www.scopus.com/inward/record.url?eid=2-s2.0-15944408038&partnerID=MN8TOARS
2005 journal article
Exploratory visual analysis of pharmacogenomic results.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. http://europepmc.org/abstract/med/15759635
2004 article
EXPLORATORY VISUAL ANALYSIS OF PHARMACOGENOMIC RESULTS
REIF, D. A. V. I. D. M., DUDEK, S. C. O. T. T. M., SHAFFER, C. H. R. I. S. T. I. A. N. M., WANG, J. A. N. E. Y., & MOORE, J. A. S. O. N. H. (2004, December 1). Biocomputing 2005 - Proceedings of the Pacific Symposium.
2004 article
Integrated analysis of genetic, genomic and proteomic data
Reif, D. M., White, B. C., & Moore, J. H. (2004, June 1). Expert Review of Proteomics, Vol. 1, p. 67â75.
Contributors: * , B. White * & J. Moore *
2004 article
The effect of bioactive glass ceramics on the expression of bone‐related genes and proteins in vitro
Knabe, C., Stiller, M., Berger, G., Reif, D., Gildenhaar, R., Howlett, C. R., & Zreiqat, H. (2004, August 13). Clinical Oral Implants Research, Vol. 16, pp. 119–127.
2003 article
Complex Function Sets Improve Symbolic Discriminant Analysis of Microarray Data
Reif, D. M., White, B. C., Olsen, N., Aune, T., & Moore, J. H. (2003, January 1). Lecture Notes in Computer Science, p. 2277â2287.
2003 book
Complex function sets improve symbolic discriminant analysis of microarray data
In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 2724, pp. 2277–2287). http://www.scopus.com/inward/record.url?eid=2-s2.0-33744780676&partnerID=MN8TOARS
Employment
Updated: November 2nd, 2022 14:26
2022 - present
2020 - 2022
2013 - 2020
2008 - 2012
2006 - 2008
Education
Updated: July 22nd, 2014 00:15