Works (27)

2019 journal article

Cheminformatics approach to exploring and modeling trait-associated metabolite profiles

JOURNAL OF CHEMINFORMATICS, 11.

Source: Web Of Science
Added: July 15, 2019

2018 journal article

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial

DIABETES CARE, 41(11), 2404–2413.

By: M. Morieri, H. Gao, M. Pigeyre, H. Shah, J. Sjaarda, C. Mendonca, T. Hastings, P. Buranasupkajorn ...

Source: NC State University Libraries
Added: November 5, 2018

2018 journal article

Sphingolipid metabolic pathway impacts thiazide diuretics blood pressure response: Insights from genomics, metabolomics, and lipidomics

Journal of the American Heart Association, 7(1).

By: M. Shahin, Y. Gong, R. Frye, D. Rotroff, A. Beitelshees, R. Baillie, A. Chapman, J. Gums ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Assessment of potential miRNA biomarkers of VERO-cell tumorigenicity in a new line (AGMK1-9T7) of African green monkey kidney cells

Vaccine, 35(41), 5503–5509.

By: B. Teferedegne, D. Rotroff, J. Macauley, G. Foseh, G. Lewis, A. Motsinger-Rief, A. Lewis

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial

PeerJ, 5.

By: S. Marvel, D. Rotroff, M. Wagner, J. Buse, T. Havener, H. McLeod, A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2017 article

Common genetic variants in neurobeachin (nbea) are associated with metformin drug response in individuals with type 2 diabetes in the accord clinical trial

Clinical Pharmacology & Therapeutics, Vol. 101, pp. S9–9.

By: D. Rotroff, S. Marvel, J. Jack, T. Havener, A. Doria, H. Shah, J. Mychaleckyi, H. McLeod ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Data descriptor: Targeted metabolomics and medication classification data from participants in the ADNI1 cohort

Scientific Data, 4.

By: L. St John-Williams, C. Blach, J. Toledo, D. Rotroff, S. Kim, K. Klavins, R. Baillie, X. Han ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Metabolic network failures in Alzheimer's disease: A biochemical road map

Alzheimers & Dementia, 13(9), 965–984.

By: J. Toledo, M. Arnold, G. Kastenmuller, R. Chang, R. Baillie, X. Han, M. Thambisetty, J. Tenenbaum ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: Effects of estradiol and progesterone addback

Translational Psychiatry, 7.

By: T. Nguyen, J. Reuter, N. Gaikwad, D. Rotroff, H. Kucera, A. Motsinger-Reif, C. Smith, L. Nieman ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Tumor exome sequencing and copy number alterations reveal potential predictors of intrinsic resistance to multi-targeted tyrosine kinase inhibitors

Oncotarget, 8(70), 115114–115127.

By: N. Gillis, D. Rotroff, T. Mesa, J. Yao, Z. Chen, M. Carulli, S. Yoder, C. Walko, J. Teer, H. McLeod

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

A genetic response score for hydrochlorothiazide use insights from genomics and metabolomics integration

Hypertension, 68(3), 621-.

By: M. Shahin, Y. Gong, C. McDonough, D. Rotroff, A. Beitelshees, T. Garrett, J. Gums, A. Motsinger-Reif ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studies

Pharmacogenetics and Genomics, 26(7), 324–333.

By: M. Irvin, D. Rotroff, S. Aslibekyan, D. Zhi, B. Hidalgo, A. Motsinger-Reif, S. Marvel, V. Srinivasasainagendra ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Analysis of the effects of cell stress and cytotoxicity on in vitro assay activity across a diverse chemical and assay space

Toxicological Sciences, 152(2), 323–339.

By: R. Judson, K. Houck, M. Martin, A. Richard, T. Knudsen, I. Shah, S. Little, J. Wambaugh ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Comprehensive genomic characterization of five canine lymphoid tumor cell lines

BMC Veterinary Research, 12.

By: S. Roode, D. Rotroff, K. Richards, P. Moore, A. Motsinger-Reif, Y. Okamura, T. Mizuno, H. Tsujimoto, S. Suter, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2016 review

Embracing integrative multiomics approaches

[Review of ]. International Journal of Genomics.

By: D. Rotroff & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Incorporating concomitant medications into genome-wide analyses for the study of complex disease and drug response

Frontiers in Genetics, 7.

By: H. Graham, D. Rotroff, S. Marvel, J. Buse, T. Havener, A. Wilson, M. Wagner, A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero

BMC Genomics, 17.

By: D. Rotroff, B. Joubert, S. Marvel, S. Haberg, M. Wu, R. Nilsen, P. Ueland, W. Nystad, S. London, A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: New mechanistic insights for rapid acting antidepressants

Translational Psychiatry, 6.

By: D. Rotroff, D. Corum, A. Motsinger-Reif, O. Fiehn, N. Bottrel, W. Drevets, J. Singh, G. Salvadore, R. Kaddurah-Daouk

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Pharmacometabolomic assessment of metformin in non-diabetic, African Americans

Frontiers in Pharmacology, 7.

By: D. Rotroff, N. Oki, X. Liang, S. Yee, S. Stocker, D. Corum, M. Meisner, O. Fiehn ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

Nature Genetics, 48(9), 1055-.

By: K. Zhou, S. Yee, E. Seiser, N. Leeuwen, R. Tavendalel, A. Bennett, C. Groves, R. Coleman ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation

Chromosome Research, 23(4), 681–708.

By: S. Roode, D. Rotroff, A. Avery, S. Suter, D. Bienzle, J. Schiffman, A. Motsinger-Reif, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Integrated model of chemical perturbations of a biological pathway using 18 in vitro high-throughput screening assays for the estrogen receptor

Toxicological Sciences, 148(1), 137–154.

By: R. Judson, F. Magpantay, V. Chickarmane, C. Haskell, N. Tania, J. Taylor, M. Xia, R. Huang ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma

Chromosome Research, 22(3), 305–319.

By: R. Thomas, L. Borst, D. Rotroff, A. Motsinger-Reif, K. Lindblad-Toh, J. Modiano, M. Breen

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Lymphoblastoid cell lines models of drug response: Successes and lessons from this pharmacogenomic model

Current Molecular Medicine, 14(7), 833–840.

By: J. Jack, D. Rotroff & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

PGxClean: a quality control GUI for the Affymetrix DMET chip and other candidate gene studies with non-biallelic alleles

Biodata Mining, 7.

By: D. Rotroff, J. Jack, N. Campbell, S. Clark & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Binary classification of a large collection of environmental chemicals from estrogen receptor assays by quantitative structure-activity relationship and machine learning methods

Journal of Chemical Information and Modeling, 53(12), 3244–3261.

By: Q. Zang, D. Rotroff & R. Judson

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine

Pharmacogenomics, 14(16), 1929–1931.

By: D. Rotroff, R. Thomas, M. Breen & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018