David Nieman

Works (10)

Updated: February 3rd, 2024 05:01

2023 journal article

Almond intake alters the acute plasma dihydroxy-octadecenoic acid (DiHOME) response to eccentric exercise

FRONTIERS IN NUTRITION, 9.

By: D. Nieman*, A. Omar*, C. Kay n , D. Kasote  n, C. Sakaguchi *, A. Lkhagva*, M. Weldemariam*, Q. Zhang *

author keywords: almonds; exercise; oxylipins; inflammation; cytokines; metabolites; (poly)phenols
TL;DR: Positive effects of almond intake in improving mood state, retaining strength, decreasing muscle damage, increasing the generation of gut-derived phenolic metabolites, and altering the plasma oxylipin DiHOME response to unaccustomed eccentric exercise in untrained adults are supported. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: February 13, 2023

2023 journal article

Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins

FRONTIERS IN NUTRITION, 10.

By: D. Nieman*, J. Woo *, C. Sakaguchi *, A. Omar*, Y. Tang *, K. Davis*, A. Pecorelli n , G. Valacchi n , Q. Zhang *

author keywords: astaxanthin; exercise; proteomics; oxylipins; inflammation; cytokines
TL;DR: It is supported that 4-week astaxanthin versus placebo supplementation did not counter exercise-induced increases in plasma cytokines and oxylipins but was linked to normalization of post-exercise plasma levels of numerous immune-related proteins including immunoglobulins within 24 h. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 17, 2023

2023 journal article

Blueberry intake elevates post-exercise anti-inflammatory oxylipins: a randomized trial

SCIENTIFIC REPORTS, 13(1).

By: D. Nieman*, C. Sakaguchi *, A. Omar*, K. Davis*, C. Shaffner*, R. Strauch n, M. Lila n , Q. Zhang *

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2023 journal article

Influence of 2 Weeks of Mango Ingestion on Inflammation Resolution after Vigorous Exercise

NUTRIENTS, 16(1).

By: C. Sakaguchi *, D. Nieman*, A. Omar*, R. Strauch n, J. Williams *, M. Lila n , Q. Zhang *

author keywords: mangoes; exercise; inflammation; metabolites; gallotannins; oxylipins; tandem mass spectrometry
TL;DR: The 2.25 h cycling bouts induced significant inflammation, but no countermeasure effect was found after 2 weeks of mango ingestion despite the elevation of mango gut-derived phenolic metabolites. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 26, 2024

2022 journal article

Enhancing the Cognitive Effects of Flavonoids With Physical Activity: Is There a Case for the Gut Microbiome?

Frontiers in Neuroscience, 16.

By: C. Cheatham *, D. Nieman*, A. Neilson n  & M. Lila n 

author keywords: age-related; cognition; neuroprotective; phenolic metabolites; prebiotic flavonoids; exercise; microbiome
TL;DR: There is a potential for combined impacts of flavonoids intake and physical exertion on cognitive function, as modulated by the gut microbiome, and that the combination of a flavonoid-rich diet and routine aerobic exercise may potentiate cognitive benefits and reduce cognitive decline in an aging population, via mechanisms mediated by the Gut microbiome. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: March 28, 2022

2021 journal article

Phytoecdysteroids Do Not Have Anabolic Effects in Skeletal Muscle in Sedentary Aging Mice

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(2).

By: M. Lawrence *, K. Zwetsloot *, S. Arthur*, C. Sherman*, J. Huot *, V. Badmaev *, M. Grace n , M. Lila n , D. Nieman*, R. Shanely *

author keywords: skeletal muscle; hypertrophy; Akt; atrogenes; 20-hydroxyecdysone
MeSH headings : Aging; Anabolic Agents; Animals; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Rats
TL;DR: Data indicate that phytoecdysteroid treatment does not alter muscle mass or fiber type, nor does it activate protein synthesis signaling in the skeletal muscle of sedentary aging mice. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 7, 2021

2020 journal article

Blueberry and/or Banana Consumption Mitigate Arachidonic, Cytochrome P450 Oxylipin Generation During Recovery From 75-Km Cycling: A Randomized Trial

FRONTIERS IN NUTRITION, 7.

By: D. Nieman*, N. Gillitt*, G. Chen *, Q. Zhang *, W. Sha *, C. Kay n , P. Chandra  n, K. Kay*, M. Lila n 

author keywords: exercise; lipid mediators; carbohydrate; polyphenols; metabolites; inflammation; fatty acids
TL;DR: Heavy exertion evoked a transient but robust increase in plasma levels of oxylipins in cyclists, with a strong attenuation effect linked to both chronic blueberry and acute banana intake on pro-inflammatory ARA-CYP oxylIPins. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 21, 2020

2020 journal article

Postexercise Inflammasome Activation and IL-1 beta Production Mitigated by Flavonoid Supplementation in Cyclists

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(6), 396–404.

By: D. Nieman*, F. Ferrara*, A. Pecorelli* , B. Woodby*, A. Hoyle*, A. Simonson*, G. Valacchi* 

author keywords: cytokines; gasdermin D; IL-18; inflammation
TL;DR: The data indicate that 2-week FLAV ingestion mitigated inflammasome activation, with a corresponding decrease in IL-1β release in cyclists after a 75-km cycling time trial, and support the strategy of ingesting high amounts of FLAV to mitigate postexercise inflammation. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: November 9, 2020

2019 article

Immunometabolism: A Multi-Omics Approach to Interpreting the Influence of Exercise and Diet on the Immune System

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 10, Vol. 10, pp. 341–363.

By: D. Nieman*, M. Lila n  & N. Gillitt*

author keywords: exercise; diet; immune function; metabolomics; lipidomics; proteomics
MeSH headings : Diet; Exercise; Humans; Immune System; Metabolism
TL;DR: Emerging evidence using large multi-omics data sets supports the combined intake of fruit sugars and phytochemicals by athletes during heavy exertion as an effective strategy to improve metabolic recovery, augment viral defense, and counter postexercise inflammation and immune dysfunction at the cell level. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 22, 2019

2019 journal article

Mixed Flavonoid Supplementation Attenuates Postexercise Plasma Levels of 4-Hydroxynonenal and Protein Carbonyls in Endurance Athletes

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(2), 112–119.

By: D. Nieman*, G. Valacchi* , L. Wentz *, F. Ferrara*, A. Pecorelli* , B. Woodby*, C. Sakaguchi *, A. Simonson*

author keywords: inflammation exercise; oxidative stress; peripheral blood mononuclear cells
TL;DR: Flavonoid supplementation prior to intensive exercise decreased plasma peroxidation and oxidative damage, as determined by 4-hydroxynonenal. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: July 6, 2020

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.