@article{choudhary_lamichhane_singamsetty_vo_brombacher_patial_saini_2024, title={Cell-Specific Contribution of IL-4 Receptor α Signaling Shapes the Overall Manifestation of Allergic Airway Disease}, volume={71}, ISSN={["1535-4989"]}, url={https://doi.org/10.1165/rcmb.2024-0208OC}, DOI={10.1165/rcmb.2024-0208OC}, abstractNote={IL-4 and IL-13 play a critical role in allergic asthma pathogenesis via their common receptor, i.e., IL4Rα. However, the cell-specific role of IL4Rα in mixed allergens (MA)-induced allergic asthma has remained unclear. Therefore, we aimed to identify the cell-specific contribution of IL4Rα signaling in the manifestation of various pathological outcomes in mice with allergic airway disease. We compared MA-induced pathological outcomes between hematopoietic progenitor cells (HPCs)- or non-HPCs-specific IL4Rα-deficient chimera, myeloid cell-specific IL4Rα-deficient (LysMcre}, number={6}, journal={AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY}, author={Choudhary, Ishita and Lamichhane, Richa and Singamsetty, Dhruthi and Vo, Thao and Brombacher, Frank and Patial, Sonika and Saini, Yogesh}, year={2024}, month={Dec}, pages={702–717} }